Secukinumab Injection

Generic name: Pronounced as (sek'' ue kin' ue mab)
Brand names
  • Cosentyx®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 08/15/2020

Secukinumab injection is used to treat moderate to severe plaque psoriasis (a skin disease in which red, scaly patches form on some areas of the body) in adults whose psoriasis is too severe to be treated by topical medications alone. It is also used in adults to treat psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin). Secukinumab injection is used in adults to treat ankylosing spondylitis (a condition in which the body attacks the joints of the spine and other areas, causing pain, swelling, and joint damage). It is also used in adults to treat active non-radiographic axial spondyloarthritis (a condition in which the body attacks the joints of the spine and other areas, causing pain and signs of swelling, but without changes seen on x-ray). Secukinumab injection is in a class of medications called monoclonal antibodies. It works by stopping the action of certain cells in the body that cause the symptoms of psoriasis.

Secukinumab injection comes as a prefilled syringe, a dosing pen, and as a powder to be mixed with liquid and injected subcutaneously (under the skin). It is usually injected once every wee k for the first 5 doses and then once every 4 weeks. For psoriatic arthritis, ankylosing spondylitis, and axial spondyloarthritis, it may also be injected once every 4 weeks. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use secukinumab injection exactly as directed. Do not inject more or less of it or inject it more often than prescribed by your doctor.

You may receive your first subcutaneous dose of secukinumab injection in your doctor's office. After that, your doctor may allow you to inject secukinumab yourself or have a friend or relative perform the injections. Before you use secukinumab injection yourself the first time, read the manufacturer's information for the patient that comes with the medication. Ask your doctor or pharmacist to show you or the person who will be injecting the medication how to inject it.

Use each syringe or dosing pen only once and inject all the solution in the syringe or pen. Dispose of used syringes and pens in a puncture-resistant container. Talk to your doctor or pharmacist about how to dispose of the puncture-resistant container.

If you are using a prefilled syringe or a dosing pen that has been refrigerated, place the syringe or pen on a flat surface without removing the needle cap and allow it warm to room temperature for 15-30 minutes before you are ready to inject the medication. Do not try to warm the medication by heating it in a microwave, placing it in hot water, or through any other method. Use the injection at least 1 hour after taking it out of the refrigerator.

Do not shake a syringe or dosing pen that contains secukinumab.

Always look at secukinumab solution before injecting it. Check that the expiration date has not passed and that the liquid is clear and colorless. The liquid should not contain visible particles. Do not use a syringe or dosing pen if it is cracked or broken, if it is expired, or if the liquid is cloudy or contains large or colored particles.

You can inject secukinumab injection anywhere on the front of your thighs (upper leg), upper outer arms, or abdomen (stomach) except your navel and the area 2 inches (5 centimeters) around it. To reduce the chances of soreness or redness, use a different site for each injection. Do not inject into an area where the skin is tender, bruised, red, or hard or where you have scars or stretch marks.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with secukinumab injection. Read the information carefully and ask your doctor or pharmacist if you have any questions.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using secukinumab injection,

  • tell your doctor and pharmacist if you are allergic to secukinumab injection, any other medications, latex, or any of the ingredients in secukinumab injection. Ask your pharmacist for a list of the ingredients. If you will be using the prefilled syringe or dosing pen, tell your doctor if you or the person who will be injecting the medication for you are allergic to rubber or latex.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants (blood thinners) such as warfarin (Coumadin, Jantoven) and medications that suppress the immune system such as cyclosporine (Gengraf, Neoral, Sandimmune). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever) or any other medical conditions.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using secukinumab injection, call your doctor.

  • check with your doctor to see if you need to receive any vaccinations. It is important to have all vaccines appropriate for your age before beginning your treatment with secukinumab injection. Do not have any vaccinations during your treatment without talking to your doctor.

  • you should know that secukinumab injection may decrease your ability to fight infection from bacteria, viruses, and fungi and increase the risk that you will get a serious or life-threatening infection. Tell your doctor if you often get any type of infection or if you have or think you may have any type of infection now. This includes minor infections (such as open cuts or sores), infections that come and go (such as herpes or cold sores), and chronic infections that do not go away. If you experience any of the following symptoms during or shortly after your treatment with secukinumab injection, call your doctor immediately: fever, sweats, or chills, muscle aches, shortness of breath, warm, red, or painful skin or sores on your body, diarrhea, stomach pain, frequent, urgent, or painful urination, or other signs of infection.

  • you should know that using secukinumab injection increases the risk that you will develop tuberculosis (TB; a serious lung infection), especially if you are already infected with tuberculosis but do not have any symptoms of the disease. Tell your doctor if you have or have ever had TB, if you have lived in a country where TB is common, or if you have been around someone who has TB. Your doctor will perform a skin test to see if you have an inactive TB infection. If necessary, your doctor will give you medication to treat this infection before you start using secukinumab injection. If you have any of the following symptoms of TB, or if you develop any of these symptoms during your treatment, call your doctor immediately: cough, coughing up blood or mucus, weakness or tiredness, weight loss, loss of appetite, chills, fever, or night sweats.

Unless your doctor tells you otherwise, continue your normal diet.

Call your doctor to ask what to do if you miss a dose of secukinumab injection. Do not use a double dose to make up for a missed one.

  • Secukinumab injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • runny, stuffed nose, sneezing

    • sore throat

    • itching

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately or get emergency medical treatment:

    • rash

    • hives

    • difficulty breathing or swallowing

    • feeling faint

    • swelling of the eyes, face, lips, tongue, throat

    • chest tightness

    • hoarseness

  • Secukinumab injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store secukinumab injection in the refrigerator but do not freeze. Keep the vials, prefilled syringe, and dosing pens in their original cartons to protect them from light.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

Ask your pharmacist any questions you have about secukinumab injection.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The metabolism of Repaglinide can be increased when combined with Secukinumab.
Montelukast Montelukast The metabolism of Montelukast can be increased when combined with Secukinumab.
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Secukinumab is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Delavirdine can be increased when combined with Secukinumab.
Nevirapine Nevirapine The metabolism of Nevirapine can be increased when combined with Secukinumab.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be increased when combined with Secukinumab.
Dolasetron Dolasetron The metabolism of Dolasetron can be increased when combined with Secukinumab.
Aminophylline Aminophylline The metabolism of Aminophylline can be increased when combined with Secukinumab.
Anagrelide Anagrelide The metabolism of Anagrelide can be increased when combined with Secukinumab.
Candesartan Candesartan The metabolism of Candesartan can be increased when combined with Secukinumab.
Cilostazol Cilostazol The metabolism of Cilostazol can be increased when combined with Secukinumab.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be increased when combined with Secukinumab.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Erythromycin can be increased when combined with Secukinumab.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be increased when combined with Secukinumab.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be increased when combined with Secukinumab.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Secukinumab.
Paregoric Paregoric The metabolism of Morphine can be increased when combined with Secukinumab.
Penbutolol Penbutolol The metabolism of Acebutolol can be increased when combined with Secukinumab.
Prednisone Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Secukinumab.
Ranitidine Ranitidine The metabolism of Ranitidine can be increased when combined with Secukinumab.
Tacrolimus Tacrolimus Tacrolimus may increase the immunosuppressive activities of Secukinumab.
Tizanidine Tizanidine The metabolism of Tizanidine can be increased when combined with Secukinumab.
Triamcinolone Triamcinolone The metabolism of Triamcinolone can be increased when combined with Secukinumab.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Secukinumab.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be increased when combined with Secukinumab.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Secukinumab.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Secukinumab.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be increased when combined with Secukinumab.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of adverse effects can be increased when Methylprednisolone is combined with Secukinumab.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be increased when combined with Secukinumab.
Metronidazole Injection Metronidazole Injection The metabolism of Metronidazole can be increased when combined with Secukinumab.
Morphine Injection Morphine Injection The metabolism of Morphine can be increased when combined with Secukinumab.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be increased when combined with Secukinumab.
Altretamine Altretamine The metabolism of Amphetamine can be increased when combined with Secukinumab.
Cyclosporine Cyclosporine Secukinumab may increase the immunosuppressive activities of Cyclosporine.
Ondansetron Ondansetron The metabolism of Ondansetron can be increased when combined with Secukinumab.
Torsemide Torsemide The metabolism of Torasemide can be increased when combined with Secukinumab.
Olanzapine Olanzapine The metabolism of Olanzapine can be increased when combined with Secukinumab.
Alosetron Alosetron The metabolism of Alosetron can be increased when combined with Secukinumab.
Dofetilide Dofetilide The metabolism of Dofetilide can be increased when combined with Secukinumab.
Hydroxychloroquine Hydroxychloroquine The metabolism of Secukinumab can be increased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The metabolism of Meloxicam can be increased when combined with Secukinumab.
Pantoprazole Pantoprazole The metabolism of Pantoprazole can be increased when combined with Secukinumab.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Secukinumab.
Zaleplon Zaleplon The metabolism of Zaleplon can be increased when combined with Secukinumab.
Anakinra Anakinra The risk or severity of adverse effects can be increased when Anakinra is combined with Secukinumab.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Secukinumab.
Trimipramine Trimipramine The metabolism of Trimipramine can be increased when combined with Secukinumab.
Etanercept Injection Etanercept Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Secukinumab.
Tenofovir Tenofovir The metabolism of Tenofovir can be increased when combined with Secukinumab.
Sirolimus Sirolimus The metabolism of Sirolimus can be increased when combined with Secukinumab.
Dutasteride Dutasteride The metabolism of Dutasteride can be increased when combined with Secukinumab.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Secukinumab.
Eplerenone Eplerenone The metabolism of Eplerenone can be increased when combined with Secukinumab.
Escitalopram Escitalopram The metabolism of Escitalopram can be increased when combined with Secukinumab.
Zonisamide Zonisamide The metabolism of Zonisamide can be increased when combined with Secukinumab.
Adalimumab Injection Adalimumab Injection The risk or severity of adverse effects can be increased when Adalimumab is combined with Secukinumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be increased when combined with Secukinumab.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be increased when combined with Secukinumab.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Glatiramer is combined with Secukinumab.
Atazanavir Atazanavir The metabolism of Atazanavir can be increased when combined with Secukinumab.
Almotriptan Almotriptan The metabolism of Almotriptan can be increased when combined with Secukinumab.
Eletriptan Eletriptan The metabolism of Eletriptan can be increased when combined with Secukinumab.
Omalizumab Injection Omalizumab Injection The risk or severity of adverse effects can be increased when Omalizumab is combined with Secukinumab.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be increased when combined with Secukinumab.
Vardenafil Vardenafil The metabolism of Vardenafil can be increased when combined with Secukinumab.
Aprepitant Aprepitant The metabolism of Aprepitant can be increased when combined with Secukinumab.
Tegaserod Tegaserod The metabolism of Tegaserod can be increased when combined with Secukinumab.
Tadalafil Tadalafil The metabolism of Tadalafil can be increased when combined with Secukinumab.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be increased when combined with Secukinumab.
Progesterone Progesterone The metabolism of Progesterone can be increased when combined with Secukinumab.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be increased when combined with Secukinumab.
Infliximab Injection Infliximab Injection The risk or severity of adverse effects can be increased when Infliximab is combined with Secukinumab.
Protriptyline Protriptyline The metabolism of Protriptyline can be increased when combined with Secukinumab.
Duloxetine Duloxetine The metabolism of Duloxetine can be increased when combined with Secukinumab.
Norethindrone Norethindrone The metabolism of Norethisterone can be increased when combined with Secukinumab.
Bosentan Bosentan The metabolism of Bosentan can be increased when combined with Secukinumab.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be increased when combined with Secukinumab.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Natalizumab.
Erlotinib Erlotinib The metabolism of Erlotinib can be increased when combined with Secukinumab.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be increased when combined with Secukinumab.
Solifenacin Solifenacin The metabolism of Solifenacin can be increased when combined with Secukinumab.
Voriconazole Voriconazole The metabolism of Voriconazole can be increased when combined with Secukinumab.
Dextroamphetamine Dextroamphetamine The metabolism of Amphetamine can be increased when combined with Secukinumab.
Entecavir Entecavir The metabolism of Entecavir can be increased when combined with Secukinumab.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Secukinumab.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Secukinumab.
Ramelteon Ramelteon The metabolism of Ramelteon can be increased when combined with Secukinumab.
Darifenacin Darifenacin The metabolism of Darifenacin can be increased when combined with Secukinumab.
Fentanyl Fentanyl The metabolism of Fentanyl can be increased when combined with Secukinumab.
Tipranavir Tipranavir The metabolism of Tipranavir can be increased when combined with Secukinumab.
Felbamate Felbamate The metabolism of Felbamate can be increased when combined with Secukinumab.
Ranolazine Ranolazine The metabolism of Ranolazine can be increased when combined with Secukinumab.
Abatacept Injection Abatacept Injection The risk or severity of adverse effects can be increased when Abatacept is combined with Secukinumab.
Rasagiline Rasagiline The metabolism of Rasagiline can be increased when combined with Secukinumab.
Imatinib Imatinib The metabolism of Imatinib can be increased when combined with Secukinumab.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be increased when combined with Secukinumab.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Secukinumab.
Gefitinib Gefitinib The metabolism of Gefitinib can be increased when combined with Secukinumab.
Paliperidone Paliperidone The metabolism of Paliperidone can be increased when combined with Secukinumab.
Bortezomib Bortezomib The metabolism of Bortezomib can be increased when combined with Secukinumab.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Secukinumab.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Secukinumab.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Secukinumab.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Secukinumab.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Secukinumab.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Secukinumab.
Primaquine Primaquine The metabolism of Primaquine can be increased when combined with Secukinumab.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Secukinumab.
Cetuximab Injection Cetuximab Injection The risk or severity of adverse effects can be increased when Cetuximab is combined with Secukinumab.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be increased when combined with Secukinumab.
Ranibizumab Injection Ranibizumab Injection The risk or severity of adverse effects can be increased when Ranibizumab is combined with Secukinumab.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be increased when combined with Secukinumab.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Vorinostat is combined with Secukinumab.
Sorafenib Sorafenib The metabolism of Sorafenib can be increased when combined with Secukinumab.
Sunitinib Sunitinib The metabolism of Sunitinib can be increased when combined with Secukinumab.
Dronabinol Dronabinol The metabolism of Dronabinol can be increased when combined with Secukinumab.
Lapatinib Lapatinib The metabolism of Lapatinib can be increased when combined with Secukinumab.
Dasatinib Dasatinib The metabolism of Dasatinib can be increased when combined with Secukinumab.
Mexiletine Mexiletine The metabolism of Mexiletine can be increased when combined with Secukinumab.
Panitumumab Injection Panitumumab Injection The risk or severity of adverse effects can be increased when Panitumumab is combined with Secukinumab.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Secukinumab.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be increased when combined with Secukinumab.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Secukinumab.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Secukinumab.
Nilotinib Nilotinib The metabolism of Secukinumab can be increased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Bexarotene can be increased when combined with Secukinumab.
Budesonide Budesonide The risk or severity of adverse effects can be increased when Budesonide is combined with Secukinumab.
Chloramphenicol Injection Chloramphenicol Injection The risk or severity of adverse effects can be increased when Chloramphenicol is combined with Secukinumab.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Secukinumab.
Etravirine Etravirine The metabolism of Etravirine can be increased when combined with Secukinumab.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Secukinumab.
Mitoxantrone Injection Mitoxantrone Injection The risk or severity of adverse effects can be increased when Mitoxantrone is combined with Secukinumab.
Cevimeline Cevimeline The metabolism of Cevimeline can be increased when combined with Secukinumab.
Nebivolol Nebivolol The metabolism of Nebivolol can be increased when combined with Secukinumab.
Tretinoin Tretinoin The metabolism of Tretinoin can be increased when combined with Secukinumab.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Secukinumab.
Flecainide Flecainide The metabolism of Flecainide can be increased when combined with Secukinumab.
Certolizumab Injection Certolizumab Injection The risk or severity of adverse effects can be increased when Certolizumab pegol is combined with Secukinumab.
Ixabepilone Injection Ixabepilone Injection The metabolism of Secukinumab can be increased when combined with Ixabepilone.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Secukinumab.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Secukinumab.
Praziquantel Praziquantel The metabolism of Praziquantel can be increased when combined with Secukinumab.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Secukinumab.
Rufinamide Rufinamide The metabolism of Rufinamide can be increased when combined with Secukinumab.
Midazolam Midazolam The metabolism of Midazolam can be increased when combined with Secukinumab.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Secukinumab.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be increased when combined with Secukinumab.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Secukinumab.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be increased when combined with Secukinumab.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be increased when combined with Secukinumab.
Betaxolol Betaxolol The metabolism of Betaxolol can be increased when combined with Secukinumab.
Iloperidone Iloperidone The metabolism of Iloperidone can be increased when combined with Secukinumab.
Prasugrel Prasugrel The metabolism of Prasugrel can be increased when combined with Secukinumab.
Lacosamide Lacosamide The metabolism of Lacosamide can be increased when combined with Secukinumab.
Everolimus Everolimus The metabolism of Everolimus can be increased when combined with Secukinumab.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be increased when combined with Secukinumab.
Dronedarone Dronedarone The metabolism of Dronedarone can be increased when combined with Secukinumab.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Pralatrexate is combined with Secukinumab.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be increased when combined with Secukinumab.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be increased when combined with Secukinumab.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Secukinumab.
Tapentadol Tapentadol The metabolism of Tapentadol can be increased when combined with Secukinumab.
Topotecan Topotecan The risk or severity of adverse effects can be increased when Topotecan is combined with Secukinumab.
Ofatumumab Injection (Chronic Lymphocytic Leukemia) Ofatumumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Ofatumumab is combined with Secukinumab.
Golimumab Injection Golimumab Injection The risk or severity of adverse effects can be increased when Golimumab is combined with Secukinumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be increased when combined with Secukinumab.
Asenapine Asenapine The metabolism of Asenapine can be increased when combined with Secukinumab.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be increased when combined with Secukinumab.
Albendazole Albendazole The metabolism of Albendazole can be increased when combined with Secukinumab.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Secukinumab.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be increased when combined with Secukinumab.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Secukinumab.
Tocilizumab Injection Tocilizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Secukinumab.
Fingolimod Fingolimod Secukinumab may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Eribulin is combined with Secukinumab.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Secukinumab.
Ustekinumab Injection Ustekinumab Injection The risk or severity of adverse effects can be increased when Ustekinumab is combined with Secukinumab.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be increased when combined with Secukinumab.
Vilazodone Vilazodone The metabolism of Vilazodone can be increased when combined with Secukinumab.
Ipilimumab Injection Ipilimumab Injection The risk or severity of adverse effects can be increased when Ipilimumab is combined with Secukinumab.
Denileukin Diftitox Injection Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Secukinumab.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Secukinumab.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Belimumab is combined with Secukinumab.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Secukinumab.
Roflumilast Roflumilast Secukinumab may increase the immunosuppressive activities of Roflumilast.
Linagliptin Linagliptin The metabolism of Linagliptin can be increased when combined with Secukinumab.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Secukinumab.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be increased when combined with Secukinumab.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Secukinumab can be increased when combined with Brentuximab vedotin.
Ruxolitinib Ruxolitinib The metabolism of Secukinumab can be increased when combined with Ruxolitinib.
Vandetanib Vandetanib The metabolism of Vandetanib can be increased when combined with Secukinumab.
Clobazam Clobazam The metabolism of Clobazam can be increased when combined with Secukinumab.
Vemurafenib Vemurafenib The metabolism of Vemurafenib can be increased when combined with Secukinumab.
Vismodegib Vismodegib The metabolism of Vismodegib can be increased when combined with Secukinumab.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Belatacept is combined with Secukinumab.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be increased when combined with Secukinumab.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Secukinumab.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Secukinumab.
Crizotinib Crizotinib The metabolism of Crizotinib can be increased when combined with Secukinumab.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Secukinumab.
Cabergoline Cabergoline The metabolism of Cabergoline can be increased when combined with Secukinumab.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be increased when combined with Secukinumab.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Secukinumab.
Pertuzumab Injection Pertuzumab Injection The risk or severity of adverse effects can be increased when Pertuzumab is combined with Secukinumab.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Carfilzomib is combined with Secukinumab.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be increased when combined with Secukinumab.
Mirabegron Mirabegron The metabolism of Mirabegron can be increased when combined with Secukinumab.
Regorafenib Regorafenib The metabolism of Regorafenib can be increased when combined with Secukinumab.
Bosutinib Bosutinib The metabolism of Secukinumab can be increased when combined with Bosutinib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of adverse effects can be increased when Corticotropin is combined with Secukinumab.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Teriflunomide is combined with Secukinumab.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be increased when combined with Secukinumab.
Tofacitinib Tofacitinib Secukinumab may increase the immunosuppressive activities of Tofacitinib.
Alogliptin Alogliptin The metabolism of Alogliptin can be increased when combined with Secukinumab.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Dimethyl fumarate is combined with Secukinumab.
Ponatinib Ponatinib The metabolism of Ponatinib can be increased when combined with Secukinumab.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Secukinumab.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Secukinumab.
Apixaban Apixaban The metabolism of Apixaban can be increased when combined with Secukinumab.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be increased when combined with Secukinumab.
Ospemifene Ospemifene The metabolism of Ospemifene can be increased when combined with Secukinumab.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Secukinumab.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be increased when combined with Secukinumab.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Secukinumab.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be increased when combined with Secukinumab.
Lomitapide Lomitapide The metabolism of Lomitapide can be increased when combined with Secukinumab.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be increased when combined with Secukinumab.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Obinutuzumab is combined with Secukinumab.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be increased when combined with Secukinumab.
Apremilast Apremilast The metabolism of Secukinumab can be increased when combined with Apremilast.
Ramucirumab Injection Ramucirumab Injection The risk or severity of adverse effects can be increased when Ramucirumab is combined with Secukinumab.
Ceritinib Ceritinib The metabolism of Ceritinib can be increased when combined with Secukinumab.
Siltuximab Injection Siltuximab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Siltuximab.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Belinostat is combined with Secukinumab.
Idelalisib Idelalisib The metabolism of Idelalisib can be increased when combined with Secukinumab.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be increased when combined with Secukinumab.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be increased when combined with Secukinumab.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be increased when combined with Secukinumab.
Suvorexant Suvorexant The metabolism of Suvorexant can be increased when combined with Secukinumab.
Dulaglutide Injection Dulaglutide Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Dulaglutide.
Pembrolizumab Injection Pembrolizumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Pembrolizumab.
Nivolumab Injection Nivolumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Nivolumab.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be increased when combined with Secukinumab.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Blinatumomab.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be increased when combined with Secukinumab.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be increased when combined with Secukinumab.
Riociguat Riociguat The metabolism of Riociguat can be increased when combined with Secukinumab.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be increased when combined with Secukinumab.
Nintedanib Nintedanib The metabolism of Nintedanib can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be increased when combined with Secukinumab.
Palbociclib Palbociclib The metabolism of Palbociclib can be increased when combined with Secukinumab.
Panobinostat Panobinostat The metabolism of Secukinumab can be increased when combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The metabolism of Haloperidol can be increased when combined with Secukinumab.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Secukinumab.
Alirocumab Injection Alirocumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Alirocumab.
Prednisolone Prednisolone The risk or severity of adverse effects can be increased when Prednisolone is combined with Secukinumab.
Evolocumab Injection Evolocumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Evolocumab.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be increased when combined with Secukinumab.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be increased when combined with Secukinumab.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be increased when combined with Secukinumab.
Cariprazine Cariprazine The metabolism of Cariprazine can be increased when combined with Secukinumab.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be increased when combined with Secukinumab.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Mepolizumab is combined with Secukinumab.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Secukinumab.
Elotuzumab Injection Elotuzumab Injection The risk or severity of adverse effects can be increased when Elotuzumab is combined with Secukinumab.
Daratumumab Injection Daratumumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Daratumumab.
Osimertinib Osimertinib The metabolism of Osimertinib can be increased when combined with Secukinumab.
Alectinib Alectinib The metabolism of Alectinib can be increased when combined with Secukinumab.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Secukinumab.
Necitumumab Injection Necitumumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Necitumumab.
Lesinurad Lesinurad The metabolism of Lesinurad can be increased when combined with Secukinumab.
Dexamethasone Injection Dexamethasone Injection The metabolism of Secukinumab can be increased when combined with Dexamethasone.
Reslizumab Injection Reslizumab Injection The risk or severity of adverse effects can be increased when Reslizumab is combined with Secukinumab.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Ixekizumab.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be increased when combined with Secukinumab.
Venetoclax Venetoclax The metabolism of Venetoclax can be increased when combined with Secukinumab.
Cobicistat Cobicistat The metabolism of Cobicistat can be increased when combined with Secukinumab.
Selexipag Selexipag The metabolism of Selexipag can be increased when combined with Secukinumab.
Atezolizumab Injection Atezolizumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Atezolizumab.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be increased when combined with Secukinumab.
Olaratumab Injection Olaratumab Injection The risk or severity of adverse effects can be increased when Olaratumab is combined with Secukinumab.
Rucaparib Rucaparib The metabolism of Rucaparib can be increased when combined with Secukinumab.
Bezlotoxumab Injection Bezlotoxumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Bezlotoxumab.
Avelumab Injection Avelumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Avelumab.
Ribociclib Ribociclib The metabolism of Ribociclib can be increased when combined with Secukinumab.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Brigatinib can be increased when combined with Secukinumab.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be increased when combined with Secukinumab.
Dupilumab Injection Dupilumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Dupilumab.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be increased when combined with Secukinumab.
Valbenazine Valbenazine The metabolism of Valbenazine can be increased when combined with Secukinumab.
Deflazacort Deflazacort The risk or severity of adverse effects can be increased when Secukinumab is combined with Deflazacort.
Ocrelizumab Injection Ocrelizumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Ocrelizumab.
Durvalumab Injection Durvalumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Durvalumab.
Sarilumab Injection Sarilumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Midostaurin can be increased when combined with Secukinumab.
Neratinib Neratinib The metabolism of Neratinib can be increased when combined with Secukinumab.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Guselkumab.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Secukinumab.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Secukinumab.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Secukinumab.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Secukinumab.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be increased when combined with Secukinumab.
Benralizumab Injection Benralizumab Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Benralizumab.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Secukinumab.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Secukinumab.
Letermovir Letermovir The metabolism of Letermovir can be increased when combined with Secukinumab.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be increased when combined with Secukinumab.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be increased when combined with Secukinumab.
Apalutamide Apalutamide The metabolism of Apalutamide can be increased when combined with Secukinumab.
Ibalizumab-uiyk Injection Ibalizumab-uiyk Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Ibalizumab.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Secukinumab.
Tildrakizumab-asmn injection Tildrakizumab-asmn injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Tildrakizumab.
Erenumab-aooe Injection Erenumab-aooe Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Erenumab.
Baricitinib Baricitinib The metabolism of Baricitinib can be increased when combined with Secukinumab.
Burosumab-twza Injection Burosumab-twza Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Burosumab.
Lofexidine Lofexidine The metabolism of Lofexidine can be increased when combined with Secukinumab.
Eliglustat Eliglustat The metabolism of Eliglustat can be increased when combined with Secukinumab.
Encorafenib Encorafenib The metabolism of Encorafenib can be increased when combined with Secukinumab.
Binimetinib Binimetinib The metabolism of Binimetinib can be increased when combined with Secukinumab.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be increased when combined with Secukinumab.
Elagolix Elagolix The metabolism of Elagolix can be increased when combined with Secukinumab.
Doravirine Doravirine The metabolism of Doravirine can be increased when combined with Secukinumab.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be increased when combined with Secukinumab.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be increased when combined with Secukinumab.
Cemiplimab-rwlc Injection Cemiplimab-rwlc Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Cemiplimab.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be increased when combined with Secukinumab.
Duvelisib Duvelisib The metabolism of Duvelisib can be increased when combined with Secukinumab.
Galcanezumab-gnlm Injection Galcanezumab-gnlm Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Galcanezumab.
Mogamulizumab-kpkc Injection Mogamulizumab-kpkc Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Mogamulizumab.
Stiripentol Stiripentol The metabolism of Stiripentol can be increased when combined with Secukinumab.
Gilteritinib Gilteritinib The metabolism of Gilteritinib can be increased when combined with Secukinumab.
Glasdegib Glasdegib The metabolism of Glasdegib can be increased when combined with Secukinumab.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be increased when combined with Secukinumab.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Secukinumab.
Prucalopride Prucalopride The metabolism of Prucalopride can be increased when combined with Secukinumab.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Emapalumab.
Romosozumab-aqqg Injection Romosozumab-aqqg Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Romosozumab.
Siponimod Siponimod The metabolism of Siponimod can be increased when combined with Secukinumab.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be increased when combined with Secukinumab.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of adverse effects can be increased when Caplacizumab is combined with Secukinumab.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be increased when combined with Secukinumab.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be increased when combined with Secukinumab.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Risankizumab.
Alpelisib Alpelisib The metabolism of Alpelisib can be increased when combined with Secukinumab.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Secukinumab.
Polatuzumab vedotin-piiq Injection Polatuzumab vedotin-piiq Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Polatuzumab vedotin.
Triclabendazole Triclabendazole The metabolism of Triclabendazole can be increased when combined with Secukinumab.
Entrectinib Entrectinib The metabolism of Entrectinib can be increased when combined with Secukinumab.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be increased when combined with Secukinumab.
Istradefylline Istradefylline The metabolism of Istradefylline can be increased when combined with Secukinumab.
Pitolisant Pitolisant The metabolism of Pitolisant can be increased when combined with Secukinumab.
Fedratinib Fedratinib The metabolism of Fedratinib can be increased when combined with Secukinumab.
Lefamulin Lefamulin The metabolism of Lefamulin can be increased when combined with Secukinumab.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be increased when combined with Secukinumab.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be increased when combined with Secukinumab.
Brolucizumab-dbll Injection Brolucizumab-dbll Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Brolucizumab.
Fam-trastuzumab deruxtecan-nxki Injection Fam-trastuzumab deruxtecan-nxki Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Trastuzumab deruxtecan.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Secukinumab.
Voxelotor Voxelotor The metabolism of Voxelotor can be increased when combined with Secukinumab.
Avapritinib Avapritinib The metabolism of Avapritinib can be increased when combined with Secukinumab.
Tazemetostat Tazemetostat The metabolism of Tazemetostat can be increased when combined with Secukinumab.
Cenobamate Cenobamate The metabolism of Cenobamate can be increased when combined with Secukinumab.
Isatuximab-irfc Injection Isatuximab-irfc Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Isatuximab.
Teprotumumab-trbw Injection Teprotumumab-trbw Injection The risk or severity of adverse effects can be increased when Teprotumumab is combined with Secukinumab.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Secukinumab is combined with Ozanimod.
Selumetinib Selumetinib The metabolism of Selumetinib can be increased when combined with Secukinumab.
Tucatinib Tucatinib The metabolism of Tucatinib can be increased when combined with Secukinumab.
Sacituzumab govitecan-hziy Injection Sacituzumab govitecan-hziy Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Sacituzumab govitecan.
Lemborexant Lemborexant The metabolism of Lemborexant can be increased when combined with Secukinumab.
Luspatercept-aamt Injection Luspatercept-aamt Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Luspatercept.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Belantamab mafodotin.
Tafasitamab-cxix Injection Tafasitamab-cxix Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Tafasitamab.
Margetuximab-cmkb Injection Margetuximab-cmkb Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Margetuximab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Secukinumab.
Evinacumab-dgnb Injection Evinacumab-dgnb Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Evinacumab.
Aducanumab-avwa Injection Aducanumab-avwa Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Aducanumab.
Anifrolumab-fnia Injection Anifrolumab-fnia Injection The risk or severity of adverse effects can be increased when Secukinumab is combined with Anifrolumab.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Secukinumab.
Indomethacin Indomethacin The metabolism of Indomethacin can be increased when combined with Secukinumab.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be increased when combined with Secukinumab.
Naproxen Naproxen The metabolism of Naproxen can be increased when combined with Secukinumab.
Trazodone Trazodone The metabolism of Trazodone can be increased when combined with Secukinumab.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Secukinumab.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Secukinumab.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be increased when combined with Secukinumab.
Methotrexate Injection Methotrexate Injection The metabolism of Secukinumab can be increased when combined with Methotrexate.
Primidone Primidone The metabolism of Primidone can be increased when combined with Secukinumab.
Methsuximide Methsuximide The metabolism of Methsuximide can be increased when combined with Secukinumab.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Secukinumab.
Diazepam Diazepam The metabolism of Diazepam can be increased when combined with Secukinumab.
Flurazepam Flurazepam The metabolism of Flurazepam can be increased when combined with Secukinumab.
Lorazepam Lorazepam The metabolism of Lorazepam can be increased when combined with Secukinumab.
Carmustine Carmustine The metabolism of Carmustine can be increased when combined with Secukinumab.
Codeine Codeine The metabolism of Codeine can be increased when combined with Secukinumab.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Secukinumab.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Secukinumab.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be increased when combined with Secukinumab.
Thioridazine Thioridazine The metabolism of Thioridazine can be increased when combined with Secukinumab.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Secukinumab.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Secukinumab.
Dapsone Dapsone The metabolism of Dapsone can be increased when combined with Secukinumab.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be increased when combined with Secukinumab.
Oxycodone Oxycodone The metabolism of Oxycodone can be increased when combined with Secukinumab.
Methadone Methadone The metabolism of Methadone can be increased when combined with Secukinumab.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be increased when combined with Secukinumab.
Benztropine Benztropine The metabolism of Benzatropine can be increased when combined with Secukinumab.
Maprotiline Maprotiline The metabolism of Maprotiline can be increased when combined with Secukinumab.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be increased when combined with Secukinumab.
Perphenazine Perphenazine The metabolism of Perphenazine can be increased when combined with Secukinumab.
Azathioprine Azathioprine The metabolism of Azathioprine can be increased when combined with Secukinumab.
Phentermine Phentermine The metabolism of Phentermine can be increased when combined with Secukinumab.
Amoxapine Amoxapine The metabolism of Amoxapine can be increased when combined with Secukinumab.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Secukinumab.
Hydrocortisone Hydrocortisone The metabolism of Hydrocortisone can be increased when combined with Secukinumab.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Secukinumab.
Doxorubicin Doxorubicin The metabolism of Secukinumab can be increased when combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Secukinumab.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Secukinumab.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Secukinumab.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be increased when combined with Secukinumab.
Clonidine Clonidine The metabolism of Clonidine can be increased when combined with Secukinumab.
Warfarin Warfarin The metabolism of Warfarin can be increased when combined with Secukinumab.
Loperamide Loperamide The metabolism of Loperamide can be increased when combined with Secukinumab.
Promethazine Promethazine The metabolism of Promethazine can be increased when combined with Secukinumab.
Daunorubicin Daunorubicin The risk or severity of adverse effects can be increased when Daunorubicin is combined with Secukinumab.
Chloroquine Chloroquine The metabolism of Chloroquine can be increased when combined with Secukinumab.
Quinine Quinine The metabolism of Quinine can be increased when combined with Secukinumab.
Ethosuximide Ethosuximide The metabolism of Ethosuximide can be increased when combined with Secukinumab.
Triamterene Triamterene The metabolism of Triamterene can be increased when combined with Secukinumab.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Secukinumab.
Desipramine Desipramine The metabolism of Desipramine can be increased when combined with Secukinumab.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be increased when combined with Secukinumab.
Imipramine Imipramine The metabolism of Imipramine can be increased when combined with Secukinumab.
Quinidine Quinidine The metabolism of Quinidine can be increased when combined with Secukinumab.
Procainamide Procainamide The metabolism of Procainamide can be increased when combined with Secukinumab.
Disopyramide Disopyramide The metabolism of Disopyramide can be increased when combined with Secukinumab.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be increased when combined with Secukinumab.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Secukinumab.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Secukinumab.
Methimazole Methimazole The risk or severity of adverse effects can be increased when Methimazole is combined with Secukinumab.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Secukinumab.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be increased when combined with Secukinumab.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be increased when combined with Secukinumab.
Tolazamide Tolazamide The metabolism of Tolazamide can be increased when combined with Secukinumab.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be increased when combined with Secukinumab.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be increased when combined with Secukinumab.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be increased when combined with Secukinumab.
Brompheniramine Brompheniramine The metabolism of Brompheniramine can be increased when combined with Secukinumab.
Meclizine Meclizine The metabolism of Meclizine can be increased when combined with Secukinumab.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be increased when combined with Secukinumab.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be increased when combined with Secukinumab.
Disulfiram Disulfiram The metabolism of Disulfiram can be increased when combined with Secukinumab.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Propranolol can be increased when combined with Secukinumab.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be increased when combined with Secukinumab.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Secukinumab.
Nadolol Nadolol The metabolism of Nadolol can be increased when combined with Secukinumab.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be increased when combined with Secukinumab.
Colchicine Colchicine The risk or severity of adverse effects can be increased when Colchicine is combined with Secukinumab.
Cephalexin Cephalexin The metabolism of Cephalexin can be increased when combined with Secukinumab.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be increased when combined with Secukinumab.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Secukinumab.
Thiotepa Injection Thiotepa Injection The metabolism of Secukinumab can be increased when combined with Thiotepa.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be increased when combined with Secukinumab.
Vinblastine Vinblastine The metabolism of Secukinumab can be increased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Metoprolol can be increased when combined with Secukinumab.
Hydroxyzine Hydroxyzine The metabolism of Hydroxyzine can be increased when combined with Secukinumab.
Thiothixene Thiothixene The metabolism of Thiothixene can be increased when combined with Secukinumab.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be increased when combined with Secukinumab.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Secukinumab.
Alprazolam Alprazolam The metabolism of Alprazolam can be increased when combined with Secukinumab.
Triazolam Triazolam The metabolism of Triazolam can be increased when combined with Secukinumab.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be increased when combined with Secukinumab.
Diltiazem Diltiazem The metabolism of Diltiazem can be increased when combined with Secukinumab.
Nifedipine Nifedipine The metabolism of Nifedipine can be increased when combined with Secukinumab.
Timolol Timolol The metabolism of Timolol can be increased when combined with Secukinumab.
Verapamil Verapamil The metabolism of Verapamil can be increased when combined with Secukinumab.
Atenolol Atenolol The metabolism of Atenolol can be increased when combined with Secukinumab.
Pindolol Pindolol The metabolism of Pindolol can be increased when combined with Secukinumab.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Secukinumab.
Piroxicam Piroxicam The metabolism of Piroxicam can be increased when combined with Secukinumab.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Secukinumab.
Etoposide Etoposide The metabolism of Etoposide can be increased when combined with Secukinumab.
Glyburide Glyburide The metabolism of Glyburide can be increased when combined with Secukinumab.
Glipizide Glipizide The metabolism of Glipizide can be increased when combined with Secukinumab.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be increased when combined with Secukinumab.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be increased when combined with Secukinumab.
Labetalol Labetalol The metabolism of Labetalol can be increased when combined with Secukinumab.
Guanabenz Guanabenz The metabolism of Guanabenz can be increased when combined with Secukinumab.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Secukinumab.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be increased when combined with Secukinumab.
Amiodarone Amiodarone The metabolism of Amiodarone can be increased when combined with Secukinumab.
Buspirone Buspirone The metabolism of Buspirone can be increased when combined with Secukinumab.
Lovastatin Lovastatin The metabolism of Lovastatin can be increased when combined with Secukinumab.
Diclofenac Diclofenac The metabolism of Diclofenac can be increased when combined with Secukinumab.
Fluoxetine Fluoxetine The metabolism of Fluoxetine can be increased when combined with Secukinumab.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Secukinumab.
Clozapine Clozapine The metabolism of Clozapine can be increased when combined with Secukinumab.
Idarubicin Idarubicin The metabolism of Idarubicin can be increased when combined with Secukinumab.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Secukinumab.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Secukinumab.
Clarithromycin Clarithromycin The metabolism of Clarithromycin can be increased when combined with Secukinumab.
Etodolac Etodolac The metabolism of Etodolac can be increased when combined with Secukinumab.
Felodipine Felodipine The metabolism of Felodipine can be increased when combined with Secukinumab.
Nabumetone Nabumetone The metabolism of Nabumetone can be increased when combined with Secukinumab.
Simvastatin Simvastatin The metabolism of Simvastatin can be increased when combined with Secukinumab.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be increased when combined with Secukinumab.
Sotalol Sotalol The metabolism of Sotalol can be increased when combined with Secukinumab.
Zolpidem Zolpidem The metabolism of Zolpidem can be increased when combined with Secukinumab.
Doxazosin Doxazosin The metabolism of Doxazosin can be increased when combined with Secukinumab.
Omeprazole Omeprazole The metabolism of Omeprazole can be increased when combined with Secukinumab.
Cisapride Cisapride The metabolism of Cisapride can be increased when combined with Secukinumab.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be increased when combined with Secukinumab.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be increased when combined with Secukinumab.
Famciclovir Famciclovir The metabolism of Famciclovir can be increased when combined with Secukinumab.
Fluvoxamine Fluvoxamine The metabolism of Fluvoxamine can be increased when combined with Secukinumab.
Nefazodone Nefazodone The metabolism of Nefazodone can be increased when combined with Secukinumab.
Losartan Losartan The metabolism of Losartan can be increased when combined with Secukinumab.
Tramadol Tramadol The metabolism of Tramadol can be increased when combined with Secukinumab.
Vinorelbine Injection Vinorelbine Injection The metabolism of Secukinumab can be increased when combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Secukinumab.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be increased when combined with Secukinumab.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Secukinumab.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Secukinumab.
Nicardipine Nicardipine The metabolism of Nicardipine can be increased when combined with Secukinumab.
Bupropion Bupropion The metabolism of Bupropion can be increased when combined with Secukinumab.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be increased when combined with Secukinumab.
Saquinavir Saquinavir The metabolism of Saquinavir can be increased when combined with Secukinumab.
Nisoldipine Nisoldipine The metabolism of Nisoldipine can be increased when combined with Secukinumab.
Riluzole Riluzole The metabolism of Riluzole can be increased when combined with Secukinumab.
Glimepiride Glimepiride The metabolism of Glimepiride can be increased when combined with Secukinumab.
Anastrozole Anastrozole The metabolism of Anastrozole can be increased when combined with Secukinumab.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Secukinumab.
Indinavir Indinavir The metabolism of Indinavir can be increased when combined with Secukinumab.
Ritonavir Ritonavir The metabolism of Ritonavir can be increased when combined with Secukinumab.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Secukinumab.
Clomipramine Clomipramine The metabolism of Clomipramine can be increased when combined with Secukinumab.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be increased when combined with Secukinumab.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be increased when combined with Secukinumab.
Zileuton Zileuton The metabolism of Zileuton can be increased when combined with Secukinumab.
Valsartan Valsartan The metabolism of Valsartan can be increased when combined with Secukinumab.
Donepezil Donepezil The metabolism of Donepezil can be increased when combined with Secukinumab.
Azithromycin Azithromycin The metabolism of Azithromycin can be increased when combined with Secukinumab.
Carvedilol Carvedilol The metabolism of Carvedilol can be increased when combined with Secukinumab.
Flutamide Flutamide The metabolism of Flutamide can be increased when combined with Secukinumab.
Selegiline Selegiline The metabolism of Selegiline can be increased when combined with Secukinumab.
Bicalutamide Bicalutamide The metabolism of Bicalutamide can be increased when combined with Secukinumab.
Sertraline Sertraline The metabolism of Sertraline can be increased when combined with Secukinumab.
Propafenone Propafenone The metabolism of Propafenone can be increased when combined with Secukinumab.
Letrozole Letrozole The metabolism of Letrozole can be increased when combined with Secukinumab.
Irbesartan Irbesartan The metabolism of Irbesartan can be increased when combined with Secukinumab.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be increased when combined with Secukinumab.
Ropinirole Ropinirole The metabolism of Ropinirole can be increased when combined with Secukinumab.
Finasteride Finasteride The metabolism of Finasteride can be increased when combined with Secukinumab.
Quetiapine Quetiapine The metabolism of Quetiapine can be increased when combined with Secukinumab.
Paroxetine Paroxetine The metabolism of Paroxetine can be increased when combined with Secukinumab.
Palivizumab Injection Palivizumab Injection The risk or severity of adverse effects can be increased when Palivizumab is combined with Secukinumab.
Citalopram Citalopram The metabolism of Citalopram can be increased when combined with Secukinumab.
Capecitabine Capecitabine The metabolism of Secukinumab can be increased when combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Efavirenz can be increased when combined with Secukinumab.
Sildenafil Sildenafil The metabolism of Sildenafil can be increased when combined with Secukinumab.
Pioglitazone Pioglitazone The metabolism of Pioglitazone can be increased when combined with Secukinumab.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Secukinumab.
Celecoxib Celecoxib The metabolism of Celecoxib can be increased when combined with Secukinumab.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be increased when combined with Secukinumab.
Tolterodine Tolterodine The metabolism of Tolterodine can be increased when combined with Secukinumab.
Thalidomide Thalidomide The metabolism of Thalidomide can be increased when combined with Secukinumab.
Nateglinide Nateglinide The metabolism of Nateglinide can be increased when combined with Secukinumab.
Galantamine Galantamine The metabolism of Galantamine can be increased when combined with Secukinumab.
Rabeprazole Rabeprazole The metabolism of Rabeprazole can be increased when combined with Secukinumab.
Terbinafine Terbinafine The metabolism of Terbinafine can be increased when combined with Secukinumab.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists