Inactive ingredients by manufacturer

Spironolactone and Hydrochlorothiazide inactive ingredients by manufacturer

Wondering whether your Spironolactone and Hydrochlorothiazide has lactose, gluten, soy, a dye or gelatin in it? The medicine is the same, but the fillers, coatings and colors differ from one company to the next. This page shows what each Spironolactone and Hydrochlorothiazide product's FDA label lists, so you can find a version that leaves out what you avoid and ask your pharmacist for it by its NDC.

We read 12 Spironolactone and Hydrochlorothiazide FDA labels from 7 companies.

Dr. Brian Staiger, PharmD, BCPS
Curated and coded by , clinical pharmacist. Updated October 6, 2026 · how this page is built

Don’t see your specific product? Ask us → A pharmacist answers, free.

Ask about your bottle

Is there something in your Spironolactone and Hydrochlorothiazide? Ask in plain words.

Name the company, strength or the NDC on your bottle and the ingredient you avoid. The answer comes only from the FDA labels on this page.

Answers are drawn from the FDA label data on this page and checked against it. They are not medical advice: confirm with your pharmacist before relying on them.

Check your bottle

Let's take a closer look at your Spironolactone and Hydrochlorothiazide.

Pick your bottle and tap what you want to check. The answer comes from that product's own FDA label, which is already on this page.

1 Which bottle do you have?

Or tap your way to it: the form, then the strength, then the company.

Form

2 What do you want to check?

Nothing tapped? We check the five big ones.

  • Listed on the labelthe company names it.
  • Not listedthe label does not name it.
  • Source unclearthe label names a starch or maltodextrin without saying what plant it came from.
  • Still being readwe have not finished this label yet.
Spironolactone and Hydrochlorothiazide Your bottle Pick a product and this label fills in.

Pick your bottle to read its label, or tap an ingredient to see which Spironolactone and Hydrochlorothiazide products leave it out.

At a glance

Which Spironolactone and Hydrochlorothiazide products list lactose, a gluten source, soy, dyes or gelatin?

  1. LactoseDiffers by manufacturer

    10 of 12 checked products list lactose; 2 do not. See which products do not list it

  2. Wheat or gluten sourceDiffers by manufacturer

    1 of 12 checked products list a wheat or gluten source; 11 do not. See which products do not list it

  3. SoyNo checked product

    No checked Spironolactone and Hydrochlorothiazide product lists soy.

  4. Synthetic dyesDiffers by manufacturer

    10 of 12 checked products list synthetic dyes; 2 do not. See which products do not list it

  5. GelatinNo checked product

    No checked Spironolactone and Hydrochlorothiazide product lists gelatin.

Also listed by some products: Corn 5 of 12 Titanium dioxide 2 of 12 PEG or polysorbate 2 of 12

Find a version without it

Every current Spironolactone and Hydrochlorothiazide product and what its label lists

Fastest way: search by NDC. It is printed on your bottle's pharmacy label. If it is not, call your pharmacy: they have it on record.

Hide products that list:

Spironolactone and Hydrochlorothiazide HYDROCHLOROTHIAZIDE 25 mg/1; SPIRONOLACTONE 25 mg tablet 1 company Lactose 1 Corn-derived 1 Synthetic dyes 1
CompanyListsInactive ingredients on the label
Safecor HealthNDC 48433-0090-20 Lactose Corn-derived Synthetic dyes
Show 11 ingredients

D&C YELLOW NO. 10 ALUMINUM LAKE, FD&C YELLOW NO. 6, LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, MENTHOL, UNSPECIFIED FORM, MICROCRYSTALLINE CELLULOSE 102, PEPPERMINT OIL, SILICON DIOXIDE, SODIUM LAURYL SULFATE, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN
Spironolactone and Hydrochlorothiazide SPIRONOLACTONE 25 mg/1; HYDROCHLOROTHIAZIDE 25 mg tablet 11 companies Wheat or gluten source 1 Corn-derived 4 Titanium dioxide 2 Polyethylene glycol or polysorbate 2 Lactose 9 Synthetic dyes 9
CompanyListsInactive ingredients on the label
AdvagenNDC 72888-0040-01 Other pack sizes, same label: 72888-0040-02, 72888-0040-03 Wheat or gluten source Corn-derived Titanium dioxide Polyethylene glycol or polysorbate
Show 14 ingredients

CALCIUM SULFATE DIHYDRATE, FERRIC OXIDE RED, FERRIC OXIDE YELLOW, FERROSOFERRIC OXIDE, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, MAGNESIUM STEARATE, MALTODEXTRIN, MODIFIED CORN STARCH (1-OCTENYL SUCCINIC ANHYDRIDE), PEPPERMINT, POLYETHYLENE GLYCOL, UNSPECIFIED, POVIDONE, UNSPECIFIED, STARCH, CORN, TITANIUM DIOXIDE
Bryant Ranch PrepackNDC 63629-1068-01 Lactose Synthetic dyes
Show 12 ingredients

ALUMINUM OXIDE, ANHYDROUS LACTOSE, D&C YELLOW NO. 10, DOCUSATE SODIUM, FD&C YELLOW NO. 6, MAGNESIUM STEARATE, MICROCRYSTALLINE CELLULOSE, PEPPERMINT, POVIDONE, UNSPECIFIED, SILICON DIOXIDE, SODIUM BENZOATE, SODIUM STARCH GLYCOLATE TYPE A POTATO
Bryant Ranch PrepackNDC 63629-1069-01 Lactose Synthetic dyes
Show 12 ingredients

ALUMINUM OXIDE, ANHYDROUS LACTOSE, D&C YELLOW NO. 10, DOCUSATE SODIUM, FD&C YELLOW NO. 6, MAGNESIUM STEARATE, MICROCRYSTALLINE CELLULOSE, PEPPERMINT, POVIDONE, UNSPECIFIED, SILICON DIOXIDE, SODIUM BENZOATE, SODIUM STARCH GLYCOLATE TYPE A POTATO
Bryant Ranch PrepackNDC 63629-1071-01 Other pack sizes, same label: 63629-1071-02, 63629-1071-03 Lactose Synthetic dyes
Show 12 ingredients

ALUMINUM OXIDE, ANHYDROUS LACTOSE, D&C YELLOW NO. 10, DOCUSATE SODIUM, FD&C YELLOW NO. 6, MAGNESIUM STEARATE, MICROCRYSTALLINE CELLULOSE, PEPPERMINT, POVIDONE, UNSPECIFIED, SILICON DIOXIDE, SODIUM BENZOATE, SODIUM STARCH GLYCOLATE TYPE A POTATO
Bryant Ranch PrepackNDC 71335-2202-01 Lactose Synthetic dyes
Show 12 ingredients

ALUMINUM OXIDE, ANHYDROUS LACTOSE, D&C YELLOW NO. 10, DOCUSATE SODIUM, FD&C YELLOW NO. 6, MAGNESIUM STEARATE, MICROCRYSTALLINE CELLULOSE, PEPPERMINT, POVIDONE, UNSPECIFIED, SILICON DIOXIDE, SODIUM BENZOATE, SODIUM STARCH GLYCOLATE TYPE A POTATO
Bryant Ranch PrepackNDC 71335-2674-01 Other pack sizes, same label: 71335-2674-02, 71335-2674-03 Lactose Synthetic dyes
Show 12 ingredients

ALUMINUM OXIDE, ANHYDROUS LACTOSE, D&C YELLOW NO. 10, DOCUSATE SODIUM, FD&C YELLOW NO. 6, MAGNESIUM STEARATE, MICROCRYSTALLINE CELLULOSE, PEPPERMINT, POVIDONE, UNSPECIFIED, SILICON DIOXIDE, SODIUM BENZOATE, SODIUM STARCH GLYCOLATE TYPE A POTATO
Bryant Ranch PrepackNDC 72162-1625-00 Other pack sizes, same label: 72162-1625-01, 72162-1625-03, 72162-1625-04, 72162-1625-05, 72162-1625-06 Lactose Synthetic dyes
Show 11 ingredients

ANHYDROUS LACTOSE, D&C YELLOW NO. 10, DOCUSATE SODIUM, FD&C YELLOW NO. 6, MAGNESIUM STEARATE, MICROCRYSTALLINE CELLULOSE, PEPPERMINT, POVIDONE, UNSPECIFIED, SILICON DIOXIDE, SODIUM BENZOATE, SODIUM STARCH GLYCOLATE TYPE A POTATO
MylanNDC 00378-0403-01 Other pack sizes, same label: 00378-0403-05 Lactose Corn-derived Synthetic dyes
Show 11 ingredients

D&C YELLOW NO. 10 ALUMINUM LAKE, FD&C YELLOW NO. 6, LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, MENTHOL, UNSPECIFIED FORM, MICROCRYSTALLINE CELLULOSE 102, PEPPERMINT OIL, SILICON DIOXIDE, SODIUM LAURYL SULFATE, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN
Mylan InstitutionalNDC 42292-0017-20 Lactose Corn-derived Synthetic dyes
Show 11 ingredients

D&C YELLOW NO. 10 ALUMINUM LAKE, FD&C YELLOW NO. 6, LACTOSE MONOHYDRATE, MAGNESIUM STEARATE, MENTHOL, UNSPECIFIED FORM, MICROCRYSTALLINE CELLULOSE 102, PEPPERMINT OIL, SILICON DIOXIDE, SODIUM LAURYL SULFATE, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN
PrascoNDC 66993-0188-02 Corn-derived Titanium dioxide Polyethylene glycol or polysorbate
Show 9 ingredients

CALCIUM SULFATE, UNSPECIFIED FORM, FERRIC OXIDE RED, HYDROXYPROPYL CELLULOSE, UNSPECIFIED, HYPROMELLOSE, UNSPECIFIED, MAGNESIUM STEARATE, POLYETHYLENE GLYCOL, UNSPECIFIED, POVIDONE, UNSPECIFIED, STARCH, CORN, TITANIUM DIOXIDE
SunNDC 53489-0144-01 Other pack sizes, same label: 53489-0144-05, 53489-0144-10 Lactose Synthetic dyes
Show 11 ingredients

anhydrous lactose, D&C yellow No. 10, docusate sodium, FD&C yellow no. 6, magnesium stearate, MICROCRYSTALLINE CELLULOSE, peppermint, POVIDONE, UNSPECIFIED, silicon dioxide, sodium benzoate, Sodium Starch Glycolate Type A Potato

A product with none of these on its label may still contain them. The label shows only what the company listed, and it often does not say where a starch or a flavor comes from. Some companies here repackage or sell another company's product under their own name. Tap an NDC to open that product's page with its full label.

Spironolactone and Hydrochlorothiazide without lactose

Lactose: milk sugar; a concern with lactose intolerance or a milk allergy. 10 of 12 checked products list lactose; 2 do not.

Show which Spironolactone and Hydrochlorothiazide products list lactose and which do not, by product and company

Does not list lactose

Lists lactose

Spironolactone and Hydrochlorothiazide without a wheat or gluten source

Wheat or gluten source: wheat, barley or rye; a concern with celiac disease or wheat allergy. 1 of 12 checked products list a wheat or gluten source; 11 do not.

Show which Spironolactone and Hydrochlorothiazide products list a wheat or gluten source and which do not, by product and company

Does not list a wheat or gluten source

Lists a wheat or gluten source

Spironolactone and Hydrochlorothiazide without synthetic dyes

Synthetic dyes: FD&C or D&C colorants and their aluminum lakes. 10 of 12 checked products list synthetic dyes; 2 do not.

Show which Spironolactone and Hydrochlorothiazide products list synthetic dyes and which do not, by product and company

Does not list synthetic dyes

Lists synthetic dyes

Spironolactone and Hydrochlorothiazide without corn-derived ingredients

Corn-derived: corn starch, maize or corn syrup; a concern with corn allergy. 5 of 12 checked products list corn-derived ingredients; 7 do not.

Show which Spironolactone and Hydrochlorothiazide products list corn-derived ingredients and which do not, by product and company

Does not list corn-derived ingredients

Lists corn-derived ingredients

Spironolactone and Hydrochlorothiazide without titanium dioxide

Titanium dioxide: A white colorant some people choose to avoid. 2 of 12 checked products list titanium dioxide; 10 do not.

Show which Spironolactone and Hydrochlorothiazide products list titanium dioxide and which do not, by product and company

Does not list titanium dioxide

Lists titanium dioxide

Spironolactone and Hydrochlorothiazide without polyethylene glycol or polysorbate

Polyethylene glycol or polysorbate: PEG, macrogol or polysorbate; a rare cause of allergic reactions. 2 of 12 checked products list polyethylene glycol or polysorbate; 10 do not.

Show which Spironolactone and Hydrochlorothiazide products list polyethylene glycol or polysorbate and which do not, by product and company

Does not list polyethylene glycol or polysorbate

Lists polyethylene glycol or polysorbate

At the pharmacy counter

How to use this at the pharmacy counter

  1. Pick the company whose list suits you and copy the NDC from the table. Many pharmacies order from wholesalers that carry several companies' versions and can request a particular one if you ask before the prescription is filled; some buy from one contracted source only, and a few insurance plans cover only certain NDCs, so ask the pharmacist to check.
  2. Treat "does not list" as exactly that. The label is what the manufacturer declared; a flavor or a starch may have an unstated source, and lines change. For celiac disease or a serious allergy, ask the manufacturer's medical information line for a written statement about the lot you have.
  3. Check the bottle each refill. A different company usually means a different shape, color and inactive-ingredient list; the pharmacist can tell you who made it, and the two-NDC comparison shows the difference line by line.
  4. If you need one company's version kept constant, ask your prescriber to write that company or the NDC on the prescription and tell the pharmacy you need it held. Rules vary by state and plan, so confirm with the pharmacist.
Ask Dr. Staiger which Spironolactone and Hydrochlorothiazide product suits you →

Common questions about Spironolactone and Hydrochlorothiazide inactive ingredients

Is Spironolactone and Hydrochlorothiazide gluten-free?
This page cannot promise any Spironolactone and Hydrochlorothiazide product has no gluten; it reports what each label declares. Of the 12 products checked, 1 lists a wheat, barley, rye or gluten ingredient (Advagen (SPIRONOLACTONE 25 mg/1; HYDROCHLOROTHIAZIDE 25 mg tablet)), and none lists a starch or maltodextrin without a stated source. If you have celiac disease, ask the manufacturer's medical information line for a written gluten statement for the lot you have.
Does Spironolactone and Hydrochlorothiazide contain lactose?
10 of 12 checked Spironolactone and Hydrochlorothiazide products list lactose; 2 do not: Advagen (SPIRONOLACTONE 25 mg/1; HYDROCHLOROTHIAZIDE 25 mg tablet) and Prasco (SPIRONOLACTONE 25 mg/1; HYDROCHLOROTHIAZIDE 25 mg tablet). The lactose in a tablet or capsule is a small amount, but people with a milk allergy or a strong intolerance often prefer a version that does not list it.
Does Spironolactone and Hydrochlorothiazide contain soy?
No checked Spironolactone and Hydrochlorothiazide product lists a soy ingredient (soybean oil or soy lecithin) on its label. Soy lecithin is the usual form and the amount is small, but people with a soy allergy often prefer a version that does not list it.
Is there a dye-free Spironolactone and Hydrochlorothiazide?
10 of 12 checked Spironolactone and Hydrochlorothiazide products list a synthetic dye (an FD&C or D&C colorant); 2 do not: Advagen (SPIRONOLACTONE 25 mg/1; HYDROCHLOROTHIAZIDE 25 mg tablet) and Prasco (SPIRONOLACTONE 25 mg/1; HYDROCHLOROTHIAZIDE 25 mg tablet). Colorants often differ by strength within one company's line, so compare the lists above strength by strength.
Does Spironolactone and Hydrochlorothiazide contain gelatin?
No checked Spironolactone and Hydrochlorothiazide product lists gelatin on its label. Gelatin is usually bovine or porcine and the label rarely says which; for kosher, halal or vegetarian needs, ask the manufacturer.
Why do the inactive ingredients differ between manufacturers?
A generic must match the brand's active ingredient, strength, dose form and how it is absorbed; its fillers, binders, coatings and colorants are the manufacturer's own choice. That is why one Spironolactone and Hydrochlorothiazide product can list lactose and a dye while another from a different company lists neither.
What can a label not tell me?
A label tells you every inactive ingredient the company names for that product. It cannot tell you where an unnamed flavor, starch or maltodextrin came from, whether traces come from shared equipment, or about a change made after our last read of the label (October 6, 2026). Your pharmacist can check with the manufacturer.
Who decides what counts as a gluten source, a dye or soy on this page?
Dr. Brian Staiger, PharmD, BCPS, a clinical pharmacist, wrote and maintains the classification this page applies: which ingredient names count as a lactose, wheat or gluten, soy, synthetic dye or gelatin source, and which read as "source not stated" (bare starch or maltodextrin). The ingredient lists themselves are the manufacturers' own FDA labels, shown as filed; nothing is added to or removed from a label.
The NDC on my bottle ends differently from the one on this page. Is it the same product?
Usually, yes. An NDC has three parts: the company, the product (the medicine, strength and form) and, last, the package size. Two codes that share the first two parts are the same product in different pack sizes, and a label belongs to the product, so every pack size shares one inactive-ingredient list. Each product on this page lists every pack size the FDA directory holds for it, and the NDC search accepts any of them.
Can my pharmacy give me a specific manufacturer's version?
Often, if you ask before the prescription is filled: many pharmacies order from wholesalers that carry several companies' versions and can request a particular one. Some pharmacies buy a generic from one contracted source only, and a few insurance plans cover only certain NDCs, so ask the pharmacist to check. Give them the NDC from this page; the company name alone is often enough.
How current is this list?
We have read the FDA labels of 12 of the 12 current Spironolactone and Hydrochlorothiazide products on the market today, from 7 companies listing it with the FDA, and lined them up side by side. The products are the ones in the FDA's current NDC directory as of October 6, 2026. The list is rebuilt every day, the FDA directory is re-imported every week, and each inactive-ingredient list is the manufacturer's FDA label as our label sync last read it, re-read when the FDA publishes a new version. Formulations change, so check the label on your own bottle and ask your pharmacist if a refill looks different.

Sources: the products are the finished Spironolactone and Hydrochlorothiazide products in the FDA's current NDC directory (openFDA), as of October 6, 2026; each inactive-ingredient list is the manufacturer's FDA Structured Product Label via DailyMed, as our label sync last read it. The concern groups are HelloPharmacist's classification of the names the label declares. Educational information only, not medical advice; confirm with your pharmacist before relying on a list. ← Back to the Spironolactone and Hydrochlorothiazide guide