Skip to the answer

Triazolam

Triazolam is a benzodiazepine sleep aid used for the short-term treatment of insomnia in adults.

Brand name Halcion
Drug class Benzodiazepine
Rx Schedule CIV Form 1
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 11 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 5, 2026
Triazolam at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Triazolam (Halcion) is a fast-acting benzodiazepine for short-term insomnia in adults that boosts GABA, the brain’s calming chemical; on the market since the early 1980s and available generically, it is an older standby kept for brief courses, not a first choice. Most people tolerate a short course well, though next-day drowsiness, dizziness and memory gaps after a dose are common. Its boxed warning matters most, since combining it with opioid pain medicines can slow breathing fatally, and regular use risks addiction and dependence. Use the lowest dose for the shortest time, skip alcohol entirely, and never stop suddenly after regular use, because withdrawal can include seizures.

Clinical pearls

  • Take it right at bedtime and only when you can stay in bed a full night before needing to be alert.
  • Skip grapefruit juice, and flag erythromycin, clarithromycin or cimetidine (a heartburn medicine), since all raise triazolam levels in the blood.
  • Ketoconazole, itraconazole, nefazodone and HIV medicines like ritonavir must never be combined with it, so mention triazolam to every new prescriber.
  • If you learn you drove, ate or made calls while asleep with no memory of it, call your doctor right away.
How we write & review this content — our editorial policy →
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

Triazolam carries three serious FDA boxed warnings — the most urgent safety alerts the FDA issues.

1. Taking triazolam with opioid pain medicines (like oxycodone or codeine) can cause profound sedation, stopped breathing, coma, or death. This combination should only be used when no other option exists, and at the lowest possible doses for the shortest possible time. Watch for very slow or shallow breathing.

2. Triazolam can be misused and is addictive. Abuse — especially when combined with alcohol, other medicines, or illicit drugs — greatly increases the risk of overdose and death. Your doctor should assess your risk before prescribing it.

3. Your body can become physically dependent on triazolam. Stopping suddenly or cutting the dose too fast after regular use can cause life-threatening withdrawal reactions, including seizures. Never stop on your own — work with your prescriber to taper the dose slowly.

Read the full warning on DailyMed →
How you get itPrescription only
Comes asTablet
Earliest FDA record1982
Companies listing it with the FDA9
FDA label last updatedJul 10, 2026
FDA’s strongest warning (boxed)Yes, read the warning

Patient information guide A plain-language walkthrough of Triazolam, written from its FDA label.

What Triazolam is used for

▾

Triazolam is a benzodiazepine approved for short-term insomnia relief in adults.

  • Halcion (triazolam) oral tablets: Short-term treatment of insomnia in adults, generally for 7 to 10 days; prescriptions should not exceed a 1-month supply
  • Triazolam oral tablets (generic): Short-term treatment of insomnia in adults, generally for 7 to 10 days; use beyond 2 to 3 weeks requires complete reevaluation for an underlying psychiatric or medical condition

How Triazolam works

▾

Triazolam is a benzodiazepine that works by attaching to GABA-A receptors — the brain's primary braking system. By binding to a specific site on these receptors, it amplifies the calming effect of GABA (gamma-aminobutyric acid), a natural brain chemical that reduces nerve activity. The result is a slower, quieter nervous system that makes falling asleep easier.

Triazolam dosage

▾

Triazolam tablets are taken by mouth once nightly, right before going to bed. They should only be taken when you have a full night ahead — do not take this medicine if you need to be awake and alert within a few hours. Always use the lowest dose that works for you; older adults are typically started at a lower dose because they clear the drug more slowly. If you and your prescriber decide to stop triazolam, the dose should be reduced gradually — never stopped suddenly.

Dosing details from the FDA-approved label

From the Triazolam prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Adults
    • 0.25 mg once daily before bedtime
    • 0.125 mg once daily may be sufficient for some patients (e.g., patients with low body weight)
    • 0.5 mg should be used only for patients who do not respond adequately to a trial of a lower dose
    • Maximum: 0.5 mg once daily
    • Use the lowest effective dose; prescribe for short-term use (7 to 10 days), not exceeding a 1-month supply; use for more than 3 weeks requires evaluation of the patient
  • Geriatric patients
    • 0.125 mg to 0.25 mg once daily
    • Initiate therapy at 0.125 mg once daily
    • 0.25 mg dose should be used only for patients who do not respond to a trial of the lower dose
    • Maximum: 0.25 mg once daily
    • Elderly patients have an increased risk of dose related adverse reactions
Read the label’s full dosing text

2 DOSAGE AND ADMINISTRATION • Adults: Recommended dosage is 0.25 mg once daily before bedtime. Maximum recommended dosage is 0.5 mg once daily ( 2.1 ) • Geriatric patients: Reduce starting dosage to 0.125 mg once daily. May increase to 0.25 mg if no response. Geriatric patients should not exceed 0.25 mg once daily ( 2.2 , 8.5 ) • Triazolam tablets should not be prescribed in quantities exceeding a 1-month supply ( 2.1 ) 2.1 Dosing Information The recommended dosage is 0.25 mg once daily before bedtime. A dosage of 0.125 mg once daily may be sufficient for some patients (e.g., patients with low body weight). A dosage of 0.5 mg should be used only for patients who do not respond adequately to a trial of a lower dose. The maximum recommended dosage is 0.5 mg once daily. Use the lowest effective dose for the patient as there are significant dose related adverse reactions. Use of triazolam tablets for more than 3 weeks requires evaluation of the patient for a primary psychiatric or medical condition [see Warnings and Precautions ( 5.4 , 5.6 )]. Prescriptions for triazolam tablets should be written for short-term use (7 to 10 days) and it should not be prescribed in quantities exceeding a 1-month supply. 2.2 Use in Geriatric Patients In geriatric patients, the recommended dosage is 0.125 mg to 0.25 mg once daily. Initiate therapy at 0.125 mg once daily. The 0.25 mg dose should be used only for patients who do not respond to a trial of the lower dose. The maximum recommended dosage is 0.25 mg once daily. Elderly patients have an increased risk of dose related adverse reactions [see Use in Specific Populations ( 8.5 )]. 2.3 Discontinuation or Dosage Reduction of Triazolam Tablets To reduce the risk of withdrawal reactions, use a gradual taper to discontinue triazolam or reduce the dosage. If a patient develops withdrawal reactions, consider pausing the taper or increasing the dosage to the previous tapered dosage level. Subsequently decrease the dosage more slowly [see Warnings and Precautions ( 5.3 ), Drug Abuse and Dependence ( 9.3 )] .

Read the full Dosage and Administration section on DailyMed →

Triazolam side effects

▾

The most common side effects of triazolam are extensions of how it works — it's a sedating medicine, so sedation-related effects are most often reported:

Common side effects

  • Drowsiness or sleepiness the next day
  • Dizziness or light-headedness
  • Headache
  • Nervousness
  • Problems with coordination or balance
  • Nausea or vomiting
  • Memory gaps (not remembering things that happened after taking the tablet)
  • Coordination problems or unsteadiness (ataxia)
  • Memory gaps for events after taking the tablet (anterograde amnesia)

When to get medical help

  • Get emergency help if you have slow, shallow, or stopped breathing — especially if you also take opioid pain medicines
  • Call your doctor right away if you do things while asleep that you don't remember — such as driving, eating, making calls, or having sex
  • Seek care immediately for swelling of the tongue, throat, or face, or trouble breathing (signs of a serious allergic reaction)
  • Call your doctor if you notice new or worsening depression, thoughts of suicide, hallucinations, agitation, or other unusual behavior changes
  • Tell your doctor if you develop increased anxiety during the day after using triazolam
  • Seek help if you experience signs of withdrawal after stopping — such as seizures, severe anxiety, or tremors

Triazolam warnings and precautions

▾
  • Opioid combination risk: Taking triazolam with opioid medicines can cause life-threatening breathing suppression, coma, or death. This combination requires close medical supervision.
  • Dependence and withdrawal: Regular use leads to physical dependence. Stopping abruptly can trigger severe withdrawal reactions, including seizures. Always taper under prescriber guidance.
  • Abuse and addiction risk: Triazolam has real potential for misuse. Risk is higher when combined with alcohol, other drugs, or illicit substances.
  • Sleep behaviors: Some users drive, eat, make calls, or have sex while asleep — with no memory of it. If this happens, contact your doctor promptly.
  • Memory effects: Triazolam is more likely than some other benzodiazepines to cause anterograde amnesia (memory gaps for events after taking it), especially if used with alcohol or when not given adequate sleep time.
  • Respiratory depression: Patients with breathing problems are at higher risk. Triazolam can worsen respiratory function.
  • Depression: Benzodiazepines may worsen depression and, in depressed patients, may increase suicidal thinking.
  • Daytime anxiety: Increased daytime anxiety can develop after as few as 10 days of use — possibly a sign of interdose withdrawal.

Triazolam interactions

▾

Triazolam has several important drug and food interactions that can raise its levels in your blood or compound its sedating effects:

  • Opioid medicines: Combining with opioids risks fatal breathing suppression — avoid unless no alternative exists, and monitor closely
  • Alcohol: Adds to sedation and significantly raises the risk of dangerous sleep behaviors — do not drink while taking triazolam
  • Strong CYP 3A inhibitors (ketoconazole, itraconazole, nefazodone, ritonavir, indinavir, nelfinavir, saquinavir, lopinavir): Triazolam is contraindicated with these — they block its breakdown and cause dangerous drug buildup
  • Macrolide antibiotics (erythromycin, clarithromycin): Raise triazolam blood levels substantially; dose reduction may be needed
  • Cimetidine: Raises triazolam levels; use with caution
  • Isoniazid: Raises triazolam levels; use with caution
  • Oral contraceptives: Modestly raise triazolam levels; be aware of increased effect
  • Grapefruit juice: Noticeably raises triazolam levels — avoid while taking this medicine
  • Other CNS depressants (antihistamines, anti-seizure drugs, other sleep medicines, some antidepressants like fluvoxamine): Add to sedation and related risks

Interactions listed in the FDA-approved label

From the Triazolam prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Opioids: Concomitant use increases the risk of respiratory depression; benzodiazepines can significantly worsen opioid-related respiratory depression. Limit dosage and duration of concomitant use, and monitor patients closely for respiratory depression and sedation.
  • Other psychotropic medications, anticonvulsants, antihistamines, ethanol, and other CNS depressant drugs: Triazolam produces additive CNS depressant effects when coadministered.
  • Ketoconazole, itraconazole, nefazodone, and several HIV protease inhibitors: These inhibit CYP 3A metabolism of triazolam, which may have a profound effect on its clearance; triazolam is contraindicated with them. Contraindicated
  • Isoniazid: Increased the maximum plasma concentration of triazolam by 20%, decreased clearance by 42%, and increased half-life by 31%. Caution is recommended during coadministration with triazolam.
  • Oral contraceptives: Increased maximum plasma concentration by 6%, decreased clearance by 32%, and increased half-life by 16%. Caution is recommended during coadministration with triazolam.
  • Grapefruit juice: Increased the maximum plasma concentration of triazolam by 25%, increased the area under the concentration curve by 48%, and increased half-life by 18%. Caution is recommended during coadministration with triazolam.
  • Fluvoxamine, diltiazem, and verapamil: Clinical data from benzodiazepines other than triazolam suggest a possible drug interaction with triazolam. Caution is recommended during coadministration with triazolam.
  • Sertraline and paroxetine: In vitro data for triazolam suggest a possible drug interaction. Caution is recommended during coadministration with triazolam.
  • Ergotamine, cyclosporine, amiodarone, nicardipine, and nifedipine: In vitro data from benzodiazepines other than triazolam suggest a possible drug interaction with triazolam. Caution is recommended during coadministration with triazolam.
  • Ranitidine: Increased the maximum plasma concentration of triazolam by 30%, increased the area under the concentration curve by 27%, and increased half-life by 3.3%. Caution is recommended during coadministration with triazolam.
Read the label’s full interactions text

Drug interactions The concomitant use of benzodiazepines and opioids increases the risk of respiratory depression because of actions at different receptor sites in the CNS that control respiration. Benzodiazepines interact at GABA A sites and opioids interact primarily at mu receptors. When benzodiazepines and opioids are combined, the potential for benzodiazepines to significantly worsen opioid-related respiratory depression exists. Limit dosage and duration of concomitant use of benzodiazepines and opioids, and monitor patients closely for respiratory depression and sedation. Both pharmacodynamic and pharmacokinetic interactions have been reported with benzodiazepines. In particular, triazolam produces additive CNS depressant effects when coadministered with other psychotropic medications, anticonvulsants, antihistamines, ethanol, and other drugs which themselves produce CNS depression. Drugs that inhibit triazolam metabolism via cytochrome P450 3A The initial step in triazolam metabolism is hydroxylation catalyzed by cytochrome P450 3A (CYP 3A). Drugs which inhibit this metabolic pathway may have a profound effect on the clearance of triazolam (see CONTRAINDICATIONS and WARNINGS for additional drugs of this type). Triazolam is contraindicated with ketoconzaole, itraconazole, nefazodone, and several HIV protease inhibitors. Drugs and other substances demonstrated to be CYP 3A inhibitors of possible clinical significance on the basis of clinical studies involving triazolam (caution is recommended during coadministration with triazolam) Isoniazid Coadministration of isoniazid increased the maximum plasma concentration of triazolam by 20%, decreased clearance by 42%, and increased half-life by 31%. Oral contraceptives Coadministration of oral contraceptives increased maximum plasma concentration by 6%, decreased clearance by 32%, and increased half-life by 16%.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

🌿197 supplements and herbs with documented Triazolam interactions, ranked by severity Check Triazolam against a supplement or herb →

Before taking Triazolam

▾
  • Pregnancy: Triazolam is contraindicated during pregnancy. It can cause birth defects and neonatal sedation or withdrawal in newborns. Women of childbearing age should use effective contraception and stop triazolam before becoming pregnant.
  • Breastfeeding: Triazolam likely passes into breast milk. Breastfeeding mothers should pump and discard milk during treatment and for 28 hours after a dose to minimize infant exposure.
  • Children: Safety and effectiveness have not been established in pediatric patients — not for use in children.
  • Older adults (65+): Build up higher levels of triazolam due to slower clearance; at higher risk of falls, over-sedation, and other dose-related side effects. A lower starting dose is recommended.
  • Depression or suicidal thoughts: Benzodiazepines can worsen depression and suicidal ideation — tell your prescriber if you have a history of either.
  • Substance use history: History of drug or alcohol misuse increases risk of triazolam dependence and addiction.
  • Breathing problems: Conditions affecting respiratory function increase risk of breathing suppression with triazolam.
  • Allergy to benzodiazepines: Triazolam is contraindicated in anyone with a known hypersensitivity to triazolam or other benzodiazepines.

Triazolam overdose

▾

Taking too much triazolam can cause extreme drowsiness, confusion, slurred speech, loss of coordination, slow or stopped breathing, and coma; death has been reported, especially when combined with alcohol. If overdose is suspected, call 911 or go to an emergency room immediately — breathing, heart rate, and blood pressure will need to be monitored and supported. A reversal agent called flumazenil may be used in a medical setting, though it carries its own risks and is not a substitute for full emergency care.

What Triazolam does in the body

▾

Triazolam produces its sleep-inducing effects by enhancing the activity of GABA, the brain's main inhibitory (calming) chemical. This reduces nervous system activity broadly — slowing thought, reducing muscle tension, and promoting sleep onset. Because of its potent CNS depressant effects, it also impairs coordination, memory, and reaction time, which is why driving and operating machinery are unsafe while taking it.

How your body processes Triazolam

▾

After swallowing a triazolam tablet, blood levels peak within about 2 hours. The drug has a relatively short half-life — roughly 1.5 to 5.5 hours — meaning most of it clears the body within a night, which limits next-day grogginess compared to longer-acting sleep medicines. Triazolam is broken down primarily by liver enzymes (specifically CYP 3A), and its breakdown products are excreted mainly in the urine. Older adults clear triazolam more slowly, leading to higher drug levels at the same dose — which is why a lower starting dose is used in that group.

How to store Triazolam

▾

Store at controlled room temperature 20° to 25°C (68° to 77°F) .

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

197

Supplements & herbs that interact with Triazolam

197 supplements and herbal products have documented interactions with Triazolam in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 9
  • Moderate · 150
  • Minor · 38
1,4-BUTANEDIOL Major ACTIVATED CHARCOAL Major BEER Major GAMMA-HYDROXYBUTYRATE (GHB) Major GRAPEFRUIT Major KAVA Major L-TRYPTOPHAN Major ST. JOHN'S WORT Major +189 more
Every supplement checked against Triazolam — ranked by severity The full interaction hub: 9 major · 150 moderate · 38 minor · every one linked to its full report. Check Triazolam against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

Triazolam: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Triazolam — the kind of thing our pharmacy team would talk through with you at the counter.

What exactly is triazolam used for?

▾
Triazolam is used for short-term relief of insomnia — trouble falling or staying asleep. It's generally prescribed for just 7 to 10 days. It's not meant to be a long-term sleep solution. If your sleep problems continue beyond 2 to 3 weeks, your doctor will want to look for an underlying cause, because ongoing insomnia can sometimes be a sign of another condition.

How and when should I take it?

▾
Take one tablet by mouth right before you get into bed — only when you have a full night ahead of you and don't need to be up and alert within several hours. Don't take it with alcohol. Always take the smallest dose your doctor prescribed, and stick to the instructions on your label. Never take an extra dose if you wake up in the middle of the night.

Can I become dependent on triazolam?

▾
Yes, this is a real concern. Your body can become physically dependent on triazolam, especially if you take it regularly or at higher doses. If you stop suddenly, you can have withdrawal symptoms — and in serious cases, even seizures. That's why you should never just quit cold turkey. Your doctor will set up a slow tapering plan when it's time to stop.

What side effects are most likely to affect me?

▾
The most common ones are drowsiness, dizziness, light-headedness, and headache — basically extensions of how the medicine makes you sleepy. Some people also notice coordination problems or memory gaps for events that happened after taking the tablet. If you experience unusual behavior changes, worsening depression, or do things in your sleep you don't remember — like driving or eating — call your doctor right away.

Are there any medicines or foods I need to avoid?

▾
Yes — a few important ones. Avoid alcohol entirely while taking triazolam, because combining them dramatically increases sedation and the risk of dangerous sleep behaviors. Grapefruit juice raises triazolam levels in your blood, so skip it during treatment. Certain antifungals (like ketoconazole or itraconazole), HIV medicines, and the antidepressant nefazodone are completely off-limits with triazolam. Opioid pain medicines combined with triazolam can cause life-threatening breathing problems. Tell every prescriber and pharmacist you see that you are taking triazolam.

Is triazolam safe during pregnancy or while breastfeeding?

▾
No — triazolam should not be used during pregnancy. It can cause harm to a developing baby, including problems at birth. If there's any chance you could become pregnant while taking it, talk to your doctor about contraception and stopping the medicine before trying to conceive. If you're breastfeeding, triazolam likely passes into your milk. You can reduce infant exposure by pumping and discarding your breast milk during treatment and for 28 hours after your last dose.

Is Triazolam available over the counter?

▾
No. Triazolam is a prescription medicine: every Triazolam product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

Is Triazolam a controlled substance?

▾
Yes — Triazolam is a federally controlled substance (Schedule IV) in the United States, so how it is prescribed, refilled and dispensed is regulated by the DEA.

When was Triazolam first available?

▾
The earliest FDA record we hold for Triazolam is from 1982: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Triazolam was first used.

Who makes Triazolam?

▾
9 companies currently list Triazolam products in the FDA's NDC Directory, including A-S Medication Solutions, Ingenus Pharmaceuticals, LLC, Mylan Pharmaceuticals Inc.. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Triazolam on HelloPharmacist

📊Triazolam supplement interactions197 checked — ranked by severity 🌿Drug & Supplement CheckerTriazolam vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Triazolam NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
Detailed data & references for Triazolam Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Triazolam forms and strengths (how it comes)

Triazolam is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Tablet

By mouth
Brands Halcion
How this form is used
What it may be used for
  • Halcion tablets are indicated for the short-term treatment of insomnia (generally 7 to 10 days) in adults
  • Triazolam tablets are indicated for the short-term treatment of insomnia (generally 7 to 10 days) in adults; use beyond 2 to 3 weeks requires a full patient reevaluation
Important instructions
  • Halcion tablets are taken once daily by mouth immediately before bedtime; prescriptions should not exceed a 1-month supply
  • Triazolam tablets are taken once daily by mouth immediately before bedtime; prescriptions should not exceed a 1-month supply
  • Halcion: older adults should start at the lower end of the dosing range — the maximum recommended dose for elderly patients is lower than for younger adults
  • Do not stop Halcion or triazolam tablets abruptly — follow your prescriber's gradual tapering plan to reduce withdrawal risk
Available strengths 2 strengths
0.125 mg 0.25 mg
28 FDA-listed product records ⓘ

Triazolam on the U.S. market: products, makers and brands

How Triazolam appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

9 companies list 14 Triazolam product records with the FDA, mostly as tablet; the earliest marketing or approval year on record is 1982. Brand names on the directory include Halcion; the rest are generics.

1
Dose forms ⓘ
9
Labelers (makers, repackagers, distributors)
1
Brand names
14
FDA-listed product records ⓘ
1982
Earliest FDA record ⓘ

Also listed with the FDA, not a patient dose form: Powder (2) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

A-S Medication Solutions14%
Ingenus Pharmaceuticals, LLC14%
Mylan Pharmaceuticals Inc.14%
Zydus Lifesciences Limited14%
Zydus Pharmaceuticals USA Inc.14%
Aphena Pharma Solutions - Tennessee, LLC7%
Other makers21%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Triazolam is used (Medicaid data)

A general measure of how commonly Triazolam is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Triazolam is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

30,954
Medicaid prescriptions filled (Q1–Q4 2025)
$337,431 gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Triazolam prescribed? Of the 1,601 medications we measure, Triazolam ranks #734 by Medicaid prescriptions — more than 54% of them.

Where Triazolam ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #734 of 1,601
#729 Halcinonide Topical 31,482 Rx #730 Tazarotene Topical 31,374 Rx #731 Atovaquone and Proguan... 31,273 Rx #732 Meropenem Injection 31,115 Rx #733 Meropenem 31,115 Rx #734 Triazolam 30,954 Rx #735 Cobicistat / Darunavir... 30,573 Rx #736 Chlorzoxazone 30,247 Rx #737 Fluorouracil Topical 30,176 Rx #738 Febuxostat 30,153 Rx #739 Isoniazid 30,009 Rx

Utilization by Triazolam product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 0.25 mg oral tablet is the most-dispensed Triazolam product — about 92% of these Medicaid prescriptions.

triazolam 0.25 MG Oral Tablet Most dispensed

28,368 Medicaid prescriptions (Q1–Q4 2025) 92% of Triazolam prescriptions shown $314,445 gross reimbursement (before rebates) ≈ $11 per prescription (gross)

Summed across the 4 of 63 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 198318

triazolam 0.125 MG Oral Tablet

2,586 Medicaid prescriptions (Q1–Q4 2025) 8% of Triazolam prescriptions shown $22,986 gross reimbursement (before rebates) ≈ $8.89 per prescription (gross)

Summed across the 3 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 198317

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Triazolam, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 7 of 74 listed Triazolam NDCs with Medicaid activity.

Compare Triazolam products

A representative set of FDA-listed product records for Triazolam — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 14 of 14 products — FDA National Drug Code Directory. See every product, package size and price: browse all 14 Triazolam NDCs →

Triazolam recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list no Triazolam recalls since July 2021.

✅No Triazolam recalls on record since July 2021

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Triazolam RxCUI 10767 1 dose form · 2 strengths
  1. Dose form (SCDF) Oral Tablet RxCUI 374197 In current FDA listings
    Clinical drug / strength (SCD) 0.125 MG RxCUI 198317 0.25 MG RxCUI 198318

Look up RxCUI 10767 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Triazolam costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet · Oral 0.125 mg $0.263 per tablet NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Triazolam brand names

Triazolam is sold under one brand name in the FDA directory — Halcion. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Halcion

Who makes Triazolam: manufacturers and labelers

9 companies list Triazolam products with the FDA. By number of product records, the largest are A-S Medication Solutions, Ingenus Pharmaceuticals, LLC, Mylan Pharmaceuticals Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

A-S Medication Solutions 2 Ingenus Pharmaceuticals, LLC 2 Mylan Pharmaceuticals Inc. 2 Zydus Lifesciences Limited 2 Zydus Pharmaceuticals USA Inc. 2 Aphena Pharma Solutions - Tennessee, LLC 1 Bryant Ranch Prepack 1 PD-Rx Pharmaceuticals, Inc. 1 Proficient Rx LP 1

Triazolam drug class (RxNorm)

Triazolam belongs to the Benzodiazepine class.

Pharmacologic class Benzodiazepine
Drug family (ATC) Benzodiazepine derivatives

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Triazolam page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Jul 10, 2026
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Triazolam.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Triazolam after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
11
Finished products in the current FDA directory
14
Companies listing them (makers, repackagers, distributors)
9
FDA labeler codes behind them ⓘ
9
Linked representative label ⓘ
Greenstone LLC
Linked label effective
Jul 10, 2026
Composite sections available
26
Linked SPL Set ID
5add318e-11b9-42f8-b052-0d8cebb32fcf
Linked SPL Document ID
27655a51-bab0-4bde-bd82-c15aa61f4705
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Greenstone LLC is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →