Isoniazid
Generic name: Pronounced as (eye soe nye' a zid)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 12/15/2016
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Brand names of combination products
- Drug interactions
IMPORTANT WARNING
Isoniazid may cause severe and sometimes fatal liver damage. Tell your doctor if you have or have ever had liver disease, if you drink or have ever drunk large amounts of alcohol, or if you are using or have ever abused injectable street drugs. If you experience any of the following symptoms, call your doctor immediately: excessive tiredness, weakness, lack of energy, loss of appetite, nausea, vomiting, dark yellow or brown urine, yellowing of the skin or eyes, pain in the upper right part of the stomach, or flu-like symptoms.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to isoniazid.
Why is this medication prescribed?
Isoniazid is used with other drugs to treat tuberculosis (TB; a serious infection that affects the lungs and sometimes other parts of the body). Isoniazid is also used with other drugs to treat people with latent (resting or nongrowing) TB including those in close contact with people who have active TB, a positive tuberculin skin test, human immunodeficiency virus (HIV), and those with pulmonary fibrosis (scarring of the lungs with an unknown cause). Isoniazid is in a class of medications called antituberculosis agents. It works by killing the bacteria that cause tuberculosis.
How should this medicine be used?
Isoniazid comes as a tablet and a solution (liquid) to take by mouth without food. Isoniazid is usually is taken once a day; it may also be taken one, two, or three times weekly. Take isoniazid at around the same time every scheduled day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take isoniazid exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor may tell you to take isoniazid for 6 months or longer. Continue to take isoniazid even if you feel well. Do not skip doses or stop taking isoniazid without talking to your doctor. Stopping isoniazid too soon may cause bacteria to become resistant to antibiotics.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking isoniazid,
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tell your doctor and pharmacist if you are allergic to isoniazid, any other medications, or any of the ingredients in isoniazid tablets or oral solution. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: acetaminophen (Tylenol), antacids, carbamazepine (Carbatrol, Equetro, Tegretol, others), citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), ketoconazole (Nizoral), paroxetine (Paxil), phenytoin (Dilantin, Phenytek), sertraline (Zoloft), theophylline (Elixophyllin, Theochron, Theo-24), and valproic acid (Depakene, Depakote). Many other medications may interact with isoniazid, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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in addition to the conditions listed in the IMPORTANT WARNING section, tell your doctor if you have or have ever had kidney disease; diabetes; tingling, burning, and pain in the fingers or toes (peripheral neuropathy); or human immunodeficiency virus (HIV).
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tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking isoniazid, call your doctor.
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you should know that you should not drink alcohol while taking this drug.
What special dietary instructions should I follow?
You will need to avoid eating foods beverages that contain very high amounts of tyramine or histamine during your treatment with isoniazid. These foods and beverages include certain cheeses, red wine, and certain fish (e.g., tuna, other tropical fish). Talk to your doctor or dietitian about which foods you should avoid during your treatment or if you do not feel well after eating or drinking certain foods while taking isoniazid.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Isoniazid may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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upset stomach
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diarrhea (when taking solution)
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If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
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eye pain
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changes in vision
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numbness or tingling in the hands and feet
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rash
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fever
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swollen glands
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sore throat
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unusual bleeding or bruising
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ongoing pain that begins in the stomach but may spread to the back
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
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nausea
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vomiting
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dizziness
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slurred speech
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vision problems
What OTHER INFORMATION should I know?
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking isoniazid.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Montelukast | Montelukast The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Montelukast is combined with Isoniazid. |
Leflunomide | Leflunomide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Leflunomide. |
Nevirapine | Nevirapine The metabolism of Nevirapine can be decreased when combined with Isoniazid. |
Atorvastatin | Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Isoniazid. |
Dolasetron | Dolasetron The risk or severity of serotonin syndrome can be increased when Dolasetron is combined with Isoniazid. |
Alendronate | Alendronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Alendronic acid is combined with Isoniazid. |
Aminophylline | Aminophylline The serum concentration of Aminophylline can be increased when it is combined with Isoniazid. |
Anagrelide | Anagrelide The metabolism of Anagrelide can be decreased when combined with Isoniazid. |
Candesartan | Candesartan The metabolism of Candesartan can be decreased when combined with Isoniazid. |
Cilostazol | Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Isoniazid. |
Clopidogrel | Clopidogrel The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Isoniazid resulting in a loss in efficacy. |
Diphenoxylate | Diphenoxylate The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Diphenoxylate. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The metabolism of Isoniazid can be decreased when combined with Conjugated estrogens. |
Fenofibrate | Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Isoniazid. |
Guanfacine | Guanfacine Isoniazid may decrease the excretion rate of Guanfacine which could result in a higher serum level. |
Magnesium Hydroxide | Magnesium Hydroxide Isoniazid may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level. |
Mycophenolate | Mycophenolate Isoniazid may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level. |
Nafarelin | Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nafarelin is combined with Isoniazid. |
Naratriptan | Naratriptan The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Naratriptan. |
Olsalazine | Olsalazine Olsalazine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Paregoric | Paregoric The risk or severity of serotonin syndrome can be increased when Morphine is combined with Isoniazid. |
Pentazocine | Pentazocine The risk or severity of serotonin syndrome can be increased when Pentazocine is combined with Isoniazid. |
Potassium | Potassium Potassium may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Prednisone | Prednisone The serum concentration of Isoniazid can be decreased when it is combined with Prednisone. |
Ranitidine | Ranitidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ranitidine is combined with Isoniazid. |
Reserpine | Reserpine Reserpine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Rizatriptan | Rizatriptan The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Rizatriptan. |
Sumatriptan | Sumatriptan The risk or severity of serotonin syndrome can be increased when Sumatriptan is combined with Isoniazid. |
Tacrolimus | Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Isoniazid. |
Tizanidine | Tizanidine The metabolism of Tizanidine can be decreased when combined with Isoniazid. |
Triamcinolone | Triamcinolone The serum concentration of Isoniazid can be decreased when it is combined with Triamcinolone. |
Zolmitriptan | Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Isoniazid. |
Ampicillin Injection | Ampicillin Injection Ampicillin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Doxycycline Injection | Doxycycline Injection Doxycycline may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Fluconazole Injection | Fluconazole Injection Fluconazole may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Foscarnet Injection | Foscarnet Injection Foscarnet may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Hydromorphone Injection | Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Isoniazid. |
Levofloxacin Injection | Levofloxacin Injection Isoniazid may decrease the excretion rate of Levofloxacin which could result in a higher serum level. |
Meperidine Injection | Meperidine Injection The metabolism of Meperidine can be decreased when combined with Isoniazid. |
Methylprednisolone Injection | Methylprednisolone Injection The serum concentration of Isoniazid can be decreased when it is combined with Methylprednisolone. |
Metoclopramide Injection | Metoclopramide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Metoclopramide. |
Metronidazole Injection | Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Isoniazid. |
Morphine Injection | Morphine Injection The risk or severity of serotonin syndrome can be increased when Morphine is combined with Isoniazid. |
Pamidronate Injection | Pamidronate Injection Pamidronic acid may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Vancomycin Injection | Vancomycin Injection Isoniazid may decrease the excretion rate of Vancomycin which could result in a higher serum level. |
Zidovudine Injection | Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Isoniazid. |
Altretamine | Altretamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Isoniazid. |
Cefuroxime | Cefuroxime Cefuroxime may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cyclosporine | Cyclosporine The metabolism of Isoniazid can be decreased when combined with Cyclosporine. |
Ondansetron | Ondansetron The metabolism of Ondansetron can be decreased when combined with Isoniazid. |
Granisetron | Granisetron The risk or severity of serotonin syndrome can be increased when Granisetron is combined with Isoniazid. |
Torsemide | Torsemide The metabolism of Torasemide can be decreased when combined with Isoniazid. |
Olanzapine | Olanzapine The metabolism of Olanzapine can be decreased when combined with Isoniazid. |
Alosetron | Alosetron The metabolism of Alosetron can be decreased when combined with Isoniazid. |
Dofetilide | Dofetilide The metabolism of Dofetilide can be decreased when combined with Isoniazid. |
Eprosartan | Eprosartan The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Eprosartan is combined with Isoniazid. |
Meloxicam | Meloxicam The metabolism of Meloxicam can be decreased when combined with Isoniazid. |
Oxcarbazepine | Oxcarbazepine The therapeutic efficacy of Oxcarbazepine can be decreased when used in combination with Isoniazid. |
Pantoprazole | Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Isoniazid. |
Risedronate | Risedronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Risedronic acid is combined with Isoniazid. |
Temozolomide | Temozolomide Temozolomide may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Zaleplon | Zaleplon The therapeutic efficacy of Zaleplon can be decreased when used in combination with Isoniazid. |
Linezolid | Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Isoniazid. |
Trimipramine | Trimipramine The metabolism of Trimipramine can be decreased when combined with Isoniazid. |
Perindopril | Perindopril Perindopril may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Tenofovir | Tenofovir Tenofovir may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Sirolimus | Sirolimus The metabolism of Sirolimus can be decreased when combined with Isoniazid. |
Eplerenone | Eplerenone The metabolism of Eplerenone can be decreased when combined with Isoniazid. |
Escitalopram | Escitalopram The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Escitalopram. |
Zonisamide | Zonisamide The metabolism of Zonisamide can be decreased when combined with Isoniazid. |
Aripiprazole | Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Isoniazid. |
Atomoxetine | Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Isoniazid. |
Dexmethylphenidate | Dexmethylphenidate The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Dexmethylphenidate. |
Atazanavir | Atazanavir Atazanavir may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Almotriptan | Almotriptan The risk or severity of serotonin syndrome can be increased when Almotriptan is combined with Isoniazid. |
Eletriptan | Eletriptan The metabolism of Eletriptan can be decreased when combined with Isoniazid. |
Mefloquine | Mefloquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Mefloquine is combined with Isoniazid. |
Rosuvastatin | Rosuvastatin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Rosuvastatin. |
Vardenafil | Vardenafil The metabolism of Vardenafil can be decreased when combined with Isoniazid. |
Alfuzosin | Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Isoniazid. |
Emtricitabine | Emtricitabine Emtricitabine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Memantine | Memantine Isoniazid may decrease the excretion rate of Memantine which could result in a higher serum level. |
Tegaserod | Tegaserod The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Tegaserod. |
Tadalafil | Tadalafil Tadalafil may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Frovatriptan | Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Isoniazid. |
Progesterone | Progesterone The metabolism of Progesterone can be decreased when combined with Isoniazid. |
Apomorphine Injection | Apomorphine Injection The risk or severity of serotonin syndrome can be increased when Apomorphine is combined with Isoniazid. |
Infliximab Injection | Infliximab Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Infliximab is combined with Isoniazid. |
Protriptyline | Protriptyline The risk or severity of serotonin syndrome can be increased when Protriptyline is combined with Isoniazid. |
Rifaximin | Rifaximin Rifaximin may increase the hepatotoxic activities of Isoniazid. |
Duloxetine | Duloxetine The metabolism of Duloxetine can be decreased when combined with Isoniazid. |
Norethindrone | Norethindrone The metabolism of Norethisterone can be decreased when combined with Isoniazid. |
Tinidazole | Tinidazole Tinidazole may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Bosentan | Bosentan The metabolism of Bosentan can be decreased when combined with Isoniazid. |
Cefditoren | Cefditoren Cefdinir may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cinacalcet | Cinacalcet The metabolism of Cinacalcet can be decreased when combined with Isoniazid. |
Cyanocobalamin Injection | Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Erlotinib | Erlotinib The metabolism of Erlotinib can be decreased when combined with Isoniazid. |
Eszopiclone | Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Isoniazid. |
Ganciclovir | Ganciclovir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Ganciclovir. |
Ribavirin | Ribavirin Ribavirin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Valganciclovir | Valganciclovir Isoniazid may decrease the excretion rate of Valganciclovir which could result in a higher serum level. |
Voriconazole | Voriconazole The metabolism of Voriconazole can be decreased when combined with Isoniazid. |
Adefovir | Adefovir Adefovir may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Dextroamphetamine | Dextroamphetamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Isoniazid. |
Entecavir | Entecavir The metabolism of Entecavir can be decreased when combined with Isoniazid. |
Ibandronate | Ibandronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ibandronate is combined with Isoniazid. |
Isocarboxazid | Isocarboxazid The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Isocarboxazid. |
Ramelteon | Ramelteon The metabolism of Ramelteon can be decreased when combined with Isoniazid. |
Fentanyl | Fentanyl The metabolism of Fentanyl can be decreased when combined with Isoniazid. |
Pregabalin | Pregabalin The therapeutic efficacy of Isoniazid can be decreased when used in combination with Pregabalin. |
Felbamate | Felbamate The metabolism of Felbamate can be decreased when combined with Isoniazid. |
Ranolazine | Ranolazine The metabolism of Isoniazid can be decreased when combined with Ranolazine. |
Rasagiline | Rasagiline The metabolism of Rasagiline can be decreased when combined with Isoniazid. |
Imatinib | Imatinib The metabolism of Imatinib can be decreased when combined with Isoniazid. |
Sitagliptin | Sitagliptin Isoniazid may decrease the excretion rate of Sitagliptin which could result in a higher serum level. |
Varenicline | Varenicline Isoniazid may decrease the excretion rate of Varenicline which could result in a higher serum level. |
Albuterol | Albuterol Isoniazid may decrease the excretion rate of Salbutamol which could result in a higher serum level. |
Paliperidone | Paliperidone The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Paliperidone. |
Bortezomib | Bortezomib The metabolism of Bortezomib can be decreased when combined with Isoniazid. |
Clofarabine Injection | Clofarabine Injection Clofarabine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Lubiprostone | Lubiprostone Isoniazid may decrease the excretion rate of Lubiprostone which could result in a higher serum level. |
Primaquine | Primaquine The metabolism of Primaquine can be decreased when combined with Isoniazid. |
Pemetrexed Injection | Pemetrexed Injection Isoniazid may decrease the excretion rate of Pemetrexed which could result in a higher serum level. |
Lisdexamfetamine | Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Lisdexamfetamine. |
Retapamulin | Retapamulin The metabolism of Retapamulin can be decreased when combined with Isoniazid. |
Sorafenib | Sorafenib The metabolism of Sorafenib can be decreased when combined with Isoniazid. |
Sunitinib | Sunitinib The metabolism of Sunitinib can be decreased when combined with Isoniazid. |
Dronabinol | Dronabinol The metabolism of Dronabinol can be decreased when combined with Isoniazid. |
Lapatinib | Lapatinib The metabolism of Lapatinib can be decreased when combined with Isoniazid. |
Levocetirizine | Levocetirizine Isoniazid may decrease the excretion rate of Levocetirizine which could result in a higher serum level. |
Pegaptanib Injection | Pegaptanib Injection Isoniazid may decrease the excretion rate of Pegaptanib which could result in a higher serum level. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be decreased when combined with Isoniazid. |
Mexiletine | Mexiletine The metabolism of Mexiletine can be decreased when combined with Isoniazid. |
Azacitidine Injection | Azacitidine Injection Azacitidine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Ivermectin | Ivermectin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ivermectin is combined with Isoniazid. |
Temsirolimus | Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Isoniazid. |
Lenalidomide | Lenalidomide Lenalidomide may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Nilotinib | Nilotinib The metabolism of Nilotinib can be decreased when combined with Isoniazid. |
Raltegravir | Raltegravir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Raltegravir. |
Bexarotene | Bexarotene The metabolism of Bexarotene can be decreased when combined with Isoniazid. |
Budesonide | Budesonide The serum concentration of Isoniazid can be decreased when it is combined with Budesonide. |
Desmopressin | Desmopressin Desmopressin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Doripenem Injection | Doripenem Injection Isoniazid may decrease the excretion rate of Doripenem which could result in a higher serum level. |
Etravirine | Etravirine The metabolism of Etravirine can be decreased when combined with Isoniazid. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection Isoniazid may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. |
Desvenlafaxine | Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Desvenlafaxine. |
Cevimeline | Cevimeline Cevimeline may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Nebivolol | Nebivolol The metabolism of Nebivolol can be decreased when combined with Isoniazid. |
Tretinoin | Tretinoin The metabolism of Tretinoin can be decreased when combined with Isoniazid. |
Bendamustine Injection | Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Isoniazid. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Isoniazid. |
Certolizumab Injection | Certolizumab Injection Isoniazid may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level. |
Ixabepilone Injection | Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Isoniazid. |
Irinotecan Injection | Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Isoniazid. |
Daptomycin Injection | Daptomycin Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Isoniazid. |
Praziquantel | Praziquantel The metabolism of Praziquantel can be decreased when combined with Isoniazid. |
Methylnaltrexone Injection | Methylnaltrexone Injection Isoniazid may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level. |
Rufinamide | Rufinamide The metabolism of Rufinamide can be decreased when combined with Isoniazid. |
Midazolam | Midazolam The serum concentration of Midazolam can be increased when it is combined with Isoniazid. |
Naltrexone Injection | Naltrexone Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Naltrexone is combined with Isoniazid. |
Dexrazoxane Injection | Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Eltrombopag | Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Isoniazid. |
Milnacipran | Milnacipran The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Milnacipran. |
Dexlansoprazole | Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Isoniazid. |
Plerixafor Injection | Plerixafor Injection Isoniazid may decrease the excretion rate of Plerixafor which could result in a higher serum level. |
Fesoterodine | Fesoterodine Isoniazid may decrease the excretion rate of Fesoterodine which could result in a higher serum level. |
Betaxolol | Betaxolol The metabolism of Betaxolol can be decreased when combined with Isoniazid. |
Iloperidone | Iloperidone The metabolism of Iloperidone can be decreased when combined with Isoniazid. |
Prasugrel | Prasugrel The metabolism of Prasugrel can be decreased when combined with Isoniazid. |
Lacosamide | Lacosamide The metabolism of Lacosamide can be decreased when combined with Isoniazid. |
Everolimus | Everolimus The metabolism of Everolimus can be decreased when combined with Isoniazid. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The metabolism of Isoniazid can be decreased when combined with Tolvaptan. |
Dronedarone | Dronedarone The metabolism of Dronedarone can be decreased when combined with Isoniazid. |
Pralatrexate Injection | Pralatrexate Injection Isoniazid may decrease the excretion rate of Pralatrexate which could result in a higher serum level. |
Palonosetron Injection | Palonosetron Injection The risk or severity of serotonin syndrome can be increased when Palonosetron is combined with Isoniazid. |
Saxagliptin | Saxagliptin Isoniazid may decrease the excretion rate of Saxagliptin which could result in a higher serum level. |
Telavancin Injection | Telavancin Injection Isoniazid may decrease the excretion rate of Telavancin which could result in a higher serum level. |
Romidepsin Injection | Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Isoniazid. |
Tapentadol | Tapentadol The metabolism of Tapentadol can be decreased when combined with Isoniazid. |
Topotecan | Topotecan Isoniazid may decrease the excretion rate of Topotecan which could result in a higher serum level. |
Pazopanib | Pazopanib The metabolism of Pazopanib can be decreased when combined with Isoniazid. |
Asenapine | Asenapine The metabolism of Asenapine can be decreased when combined with Isoniazid. |
Vigabatrin | Vigabatrin The therapeutic efficacy of Vigabatrin can be decreased when used in combination with Isoniazid. |
Pitavastatin | Pitavastatin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Pitavastatin. |
Albendazole | Albendazole The metabolism of Albendazole can be decreased when combined with Isoniazid. |
Oxymorphone | Oxymorphone The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Oxymorphone. |
Dalfampridine | Dalfampridine The risk or severity of seizure can be increased when Isoniazid is combined with Dalfampridine. |
Fingolimod | Fingolimod The metabolism of Fingolimod can be decreased when combined with Isoniazid. |
Cabazitaxel Injection | Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Isoniazid. |
Ceftaroline Injection | Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Lurasidone | Lurasidone The metabolism of Lurasidone can be decreased when combined with Isoniazid. |
Acetaminophen Injection | Acetaminophen Injection Isoniazid may increase the hepatotoxic activities of Acetaminophen. |
Vilazodone | Vilazodone The metabolism of Vilazodone can be decreased when combined with Isoniazid. |
Ipilimumab Injection | Ipilimumab Injection Isoniazid may decrease the excretion rate of Ipilimumab which could result in a higher serum level. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Terbutaline Injection | Terbutaline Injection Terbutaline may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Busulfan Injection | Busulfan Injection The metabolism of Busulfan can be decreased when combined with Isoniazid. |
Roflumilast | Roflumilast The metabolism of Roflumilast can be decreased when combined with Isoniazid. |
Linagliptin | Linagliptin The metabolism of Linagliptin can be decreased when combined with Isoniazid. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Isoniazid. |
Rivaroxaban | Rivaroxaban Isoniazid may decrease the excretion rate of Rivaroxaban which could result in a higher serum level. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Isoniazid. |
Ruxolitinib | Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Isoniazid. |
Vandetanib | Vandetanib The metabolism of Vandetanib can be decreased when combined with Isoniazid. |
Clobazam | Clobazam The metabolism of Clobazam can be decreased when combined with Isoniazid. |
Vemurafenib | Vemurafenib The metabolism of Vemurafenib can be decreased when combined with Isoniazid. |
Vismodegib | Vismodegib The metabolism of Vismodegib can be decreased when combined with Isoniazid. |
Ivacaftor | Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Isoniazid. |
Deferiprone | Deferiprone Isoniazid may decrease the excretion rate of Deferiprone which could result in a higher serum level. |
Axitinib | Axitinib The metabolism of Axitinib can be decreased when combined with Isoniazid. |
Crizotinib | Crizotinib The metabolism of Crizotinib can be decreased when combined with Isoniazid. |
Cabergoline | Cabergoline The metabolism of Isoniazid can be decreased when combined with Cabergoline. |
Naloxone Injection | Naloxone Injection Isoniazid may decrease the excretion rate of Naloxone which could result in a higher serum level. |
Fondaparinux Injection | Fondaparinux Injection Fondaparinux may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Ezogabine | Ezogabine The therapeutic efficacy of Tiagabine can be decreased when used in combination with Isoniazid. |
Iloprost | Iloprost The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Iloprost. |
Enzalutamide | Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Isoniazid. |
Mirabegron | Mirabegron Isoniazid may decrease the excretion rate of Mirabegron which could result in a higher serum level. |
Regorafenib | Regorafenib The metabolism of Regorafenib can be decreased when combined with Isoniazid. |
Bosutinib | Bosutinib The metabolism of Bosutinib can be decreased when combined with Isoniazid. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The serum concentration of Isoniazid can be decreased when it is combined with Corticotropin. |
Cabozantinib (thyroid cancer) | Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Isoniazid. |
Teduglutide Injection | Teduglutide Injection Isoniazid may decrease the excretion rate of Teduglutide which could result in a higher serum level. |
Tofacitinib | Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Isoniazid. |
Alogliptin | Alogliptin Isoniazid may decrease the excretion rate of Alogliptin which could result in a higher serum level. |
Ponatinib | Ponatinib The metabolism of Ponatinib can be decreased when combined with Isoniazid. |
Pomalidomide | Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Isoniazid. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Isoniazid. |
Apixaban | Apixaban The metabolism of Apixaban can be decreased when combined with Isoniazid. |
Canagliflozin | Canagliflozin Isoniazid may increase the excretion rate of Canagliflozin which could result in a lower serum level and potentially a reduction in efficacy. |
Methazolamide | Methazolamide Methazolamide may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Dabrafenib | Dabrafenib The metabolism of Dabrafenib can be decreased when combined with Isoniazid. |
Ospemifene | Ospemifene The metabolism of Ospemifene can be decreased when combined with Isoniazid. |
Trametinib | Trametinib Isoniazid may decrease the excretion rate of Trametinib which could result in a higher serum level. |
Levomilnacipran | Levomilnacipran The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Levomilnacipran. |
Ertapenem Injection | Ertapenem Injection Ertapenem may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Vortioxetine | Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Isoniazid. |
Perampanel | Perampanel The metabolism of Perampanel can be decreased when combined with Isoniazid. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Isoniazid. |
Lomitapide | Lomitapide The metabolism of Lomitapide can be decreased when combined with Isoniazid. |
Avanafil | Avanafil The metabolism of Avanafil can be decreased when combined with Isoniazid. |
Ketorolac Injection | Ketorolac Injection Ketorolac may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Sofosbuvir | Sofosbuvir Isoniazid may decrease the excretion rate of Sofosbuvir which could result in a higher serum level. |
Dapagliflozin | Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Isoniazid. |
Apremilast | Apremilast The metabolism of Apremilast can be decreased when combined with Isoniazid. |
Droxidopa | Droxidopa Isoniazid may decrease the excretion rate of Droxidopa which could result in a higher serum level. |
Ceritinib | Ceritinib The metabolism of Ceritinib can be decreased when combined with Isoniazid. |
Eslicarbazepine | Eslicarbazepine The therapeutic efficacy of Eslicarbazepine can be decreased when used in combination with Isoniazid. |
Idelalisib | Idelalisib The metabolism of Idelalisib can be decreased when combined with Isoniazid. |
Testosterone Injection | Testosterone Injection The metabolism of Testosterone can be decreased when combined with Isoniazid. |
Vorapaxar | Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Isoniazid. |
Hydrocodone | Hydrocodone The risk or severity of serotonin syndrome can be increased when Hydrocodone is combined with Isoniazid. |
Suvorexant | Suvorexant The metabolism of Suvorexant can be decreased when combined with Isoniazid. |
Edoxaban | Edoxaban Isoniazid may decrease the excretion rate of Edoxaban which could result in a higher serum level. |
Olaparib | Olaparib The metabolism of Olaparib can be decreased when combined with Isoniazid. |
Methamphetamine | Methamphetamine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Metamfetamine. |
Tasimelteon | Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Isoniazid. |
Pirfenidone | Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Isoniazid. |
Nintedanib | Nintedanib The metabolism of Nintedanib can be decreased when combined with Isoniazid. |
Risperidone Injection | Risperidone Injection The risk or severity of serotonin syndrome can be increased when Risperidone is combined with Isoniazid. |
Palbociclib | Palbociclib The metabolism of Palbociclib can be decreased when combined with Isoniazid. |
Naloxegol | Naloxegol The metabolism of Naloxegol can be decreased when combined with Isoniazid. |
Panobinostat | Panobinostat The metabolism of Panobinostat can be decreased when combined with Isoniazid. |
Haloperidol Injection | Haloperidol Injection The serum concentration of Isoniazid can be increased when it is combined with Haloperidol. |
Ivabradine | Ivabradine The metabolism of Ivabradine can be decreased when combined with Isoniazid. |
Amiloride | Amiloride Amiloride may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Macitentan | Macitentan Isoniazid may decrease the excretion rate of Macitentan which could result in a higher serum level. |
Sonidegib | Sonidegib The metabolism of Sonidegib can be decreased when combined with Isoniazid. |
Flibanserin | Flibanserin The metabolism of Flibanserin can be decreased when combined with Isoniazid. |
Prednisolone | Prednisolone The serum concentration of Isoniazid can be decreased when it is combined with Prednisolone. |
Brexpiprazole | Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Isoniazid. |
Ziprasidone Injection | Ziprasidone Injection The metabolism of Ziprasidone can be decreased when combined with Isoniazid. |
Cariprazine | Cariprazine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Cariprazine. |
Penicillin G Procaine Injection | Penicillin G Procaine Injection Isoniazid may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level. |
Eluxadoline | Eluxadoline The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Eluxadoline. |
Cobimetinib | Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Isoniazid. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Isoniazid. |
Osimertinib | Osimertinib The metabolism of Osimertinib can be decreased when combined with Isoniazid. |
Alectinib | Alectinib The metabolism of Alectinib can be decreased when combined with Isoniazid. |
Ixazomib | Ixazomib The metabolism of Ixazomib can be decreased when combined with Isoniazid. |
Rifapentine | Rifapentine Rifapentine may increase the hepatotoxic activities of Isoniazid. |
Lesinurad | Lesinurad The metabolism of Lesinurad can be decreased when combined with Isoniazid. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Dexamethasone Injection | Dexamethasone Injection The serum concentration of Isoniazid can be decreased when it is combined with Dexamethasone. |
Brivaracetam Injection | Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Isoniazid. |
Venetoclax | Venetoclax The metabolism of Venetoclax can be decreased when combined with Isoniazid. |
Pimavanserin | Pimavanserin The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Pimavanserin. |
Diphenhydramine Injection | Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Isoniazid. |
Furosemide Injection | Furosemide Injection Furosemide may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Rucaparib | Rucaparib The metabolism of Rucaparib can be decreased when combined with Isoniazid. |
Lixisenatide Injection | Lixisenatide Injection Isoniazid may decrease the excretion rate of Lixisenatide which could result in a higher serum level. |
Ribociclib | Ribociclib The metabolism of Ribociclib can be decreased when combined with Isoniazid. |
Brigatinib | Brigatinib The metabolism of Brigatinib can be decreased when combined with Isoniazid. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Isoniazid. |
Deutetrabenazine | Deutetrabenazine Isoniazid may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level. |
Valbenazine | Valbenazine Isoniazid may decrease the excretion rate of Valbenazine which could result in a higher serum level. |
Deflazacort | Deflazacort The serum concentration of Deflazacort can be increased when it is combined with Isoniazid. |
Safinamide | Safinamide The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Safinamide. |
Naldemedine | Naldemedine Isoniazid may decrease the excretion rate of Naldemedine which could result in a higher serum level. |
Midostaurin | Midostaurin The metabolism of Midostaurin can be decreased when combined with Isoniazid. |
Neratinib | Neratinib The metabolism of Neratinib can be decreased when combined with Isoniazid. |
Enasidenib | Enasidenib The metabolism of Enasidenib can be decreased when combined with Isoniazid. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Isoniazid. |
Benznidazole | Benznidazole Isoniazid may decrease the excretion rate of Benznidazole which could result in a higher serum level. |
Copanlisib Injection | Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Isoniazid. |
Delafloxacin | Delafloxacin Isoniazid may decrease the excretion rate of Delafloxacin which could result in a higher serum level. |
Abemaciclib | Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Isoniazid. |
Acalabrutinib | Acalabrutinib The metabolism of Acalabrutinib can be decreased when combined with Isoniazid. |
Ertugliflozin | Ertugliflozin Ertugliflozin may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Isoniazid. |
Apalutamide | Apalutamide Isoniazid may decrease the excretion rate of Apalutamide which could result in a higher serum level. |
Penicillamine | Penicillamine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Penicillamine is combined with Isoniazid. |
Baricitinib | Baricitinib The metabolism of Baricitinib can be decreased when combined with Isoniazid. |
Lofexidine | Lofexidine The metabolism of Lofexidine can be decreased when combined with Isoniazid. |
Plazomicin Injection | Plazomicin Injection Isoniazid may decrease the excretion rate of Plazomicin which could result in a higher serum level. |
Eliglustat | Eliglustat The metabolism of Eliglustat can be decreased when combined with Isoniazid. |
Binimetinib | Binimetinib The metabolism of Binimetinib can be decreased when combined with Isoniazid. |
Ivosidenib | Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Isoniazid. |
Cannabidiol | Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Isoniazid. |
Dacomitinib | Dacomitinib The metabolism of Dacomitinib can be decreased when combined with Isoniazid. |
Duvelisib | Duvelisib The metabolism of Duvelisib can be decreased when combined with Isoniazid. |
Stiripentol | Stiripentol The metabolism of Stiripentol can be decreased when combined with Isoniazid. |
Gilteritinib | Gilteritinib The metabolism of Gilteritinib can be decreased when combined with Isoniazid. |
Lorlatinib | Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Isoniazid. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Isoniazid. |
Rifamycin | Rifamycin Rifamycin may increase the hepatotoxic activities of Isoniazid. |
Prucalopride | Prucalopride The metabolism of Prucalopride can be decreased when combined with Isoniazid. |
Siponimod | Siponimod The risk or severity of adverse effects can be increased when Isoniazid is combined with Siponimod. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Erdafitinib | Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Isoniazid. |
Esomeprazole Injection | Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Isoniazid. |
Alpelisib | Alpelisib The metabolism of Alpelisib can be decreased when combined with Isoniazid. |
Brexanolone Injection | Brexanolone Injection The therapeutic efficacy of Brexanolone can be decreased when used in combination with Isoniazid. |
Cladribine | Cladribine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cladribine is combined with Isoniazid. |
Solriamfetol | Solriamfetol Isoniazid may decrease the excretion rate of Solriamfetol which could result in a higher serum level. |
Triclabendazole | Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Isoniazid. |
Entrectinib | Entrectinib The metabolism of Entrectinib can be decreased when combined with Isoniazid. |
Pexidartinib | Pexidartinib Isoniazid may increase the hepatotoxic activities of Pexidartinib. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Isoniazid. |
Pitolisant | Pitolisant Isoniazid may decrease the excretion rate of Pitolisant which could result in a higher serum level. |
Pretomanid | Pretomanid The serum concentration of Pretomanid can be increased when it is combined with Isoniazid. |
Fedratinib | Fedratinib The metabolism of Fedratinib can be decreased when combined with Isoniazid. |
Lefamulin | Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Isoniazid. |
Phenytoin Injection | Phenytoin Injection The serum concentration of Phenytoin can be increased when it is combined with Isoniazid. |
Fosphenytoin Injection | Fosphenytoin Injection The serum concentration of Fosphenytoin can be increased when it is combined with Isoniazid. |
Zanubrutinib | Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Isoniazid. |
Voxelotor | Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Isoniazid. |
Avapritinib | Avapritinib The metabolism of Avapritinib can be decreased when combined with Isoniazid. |
Lumateperone | Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Isoniazid. |
Lasmiditan | Lasmiditan The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Lasmiditan. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Isoniazid. |
Tazemetostat | Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Isoniazid. |
Cenobamate | Cenobamate The metabolism of Cenobamate can be decreased when combined with Isoniazid. |
Pemigatinib | Pemigatinib The metabolism of Pemigatinib can be decreased when combined with Isoniazid. |
Selumetinib | Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Isoniazid. |
Rimegepant | Rimegepant The metabolism of Rimegepant can be decreased when combined with Isoniazid. |
Fenfluramine | Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Isoniazid. |
Lurbinectedin Injection | Lurbinectedin Injection The serum concentration of Lurbinectedin can be increased when it is combined with Isoniazid. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Isoniazid. |
Viloxazine | Viloxazine Isoniazid may decrease the excretion rate of Viloxazine which could result in a higher serum level. |
Tobramycin Injection | Tobramycin Injection Tobramycin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Theophylline | Theophylline The serum concentration of Theophylline can be increased when it is combined with Isoniazid. |
Fenoprofen | Fenoprofen Fenoprofen may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Indomethacin | Indomethacin Indomethacin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Mefenamic Acid | Mefenamic Acid Mefenamic acid may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Naproxen | Naproxen Naproxen may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Tolmetin | Tolmetin Tolmetin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Sulindac | Sulindac Sulindac may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Trazodone | Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Isoniazid. |
Isotretinoin | Isotretinoin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Isotretinoin. |
Sucralfate | Sucralfate Sucralfate may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Floxuridine | Floxuridine Floxuridine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Phenobarbital | Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Isoniazid. |
Metaxalone | Metaxalone The risk or severity of serotonin syndrome can be increased when Metaxalone is combined with Isoniazid. |
Methotrexate Injection | Methotrexate Injection The metabolism of Isoniazid can be decreased when combined with Methotrexate. |
Levorphanol | Levorphanol The risk or severity of serotonin syndrome can be increased when Levorphanol is combined with Isoniazid. |
Primidone | Primidone The metabolism of Primidone can be decreased when combined with Isoniazid. |
Methsuximide | Methsuximide The metabolism of Methsuximide can be decreased when combined with Isoniazid. |
Diethylpropion | Diethylpropion The risk or severity of serotonin syndrome can be increased when Diethylpropion is combined with Isoniazid. |
Chlorpromazine | Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Isoniazid. |
Diazepam | Diazepam The metabolism of Diazepam can be decreased when combined with Isoniazid. |
Oxazepam | Oxazepam Oxazepam may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Flurazepam | Flurazepam The metabolism of Isoniazid can be decreased when combined with Flurazepam. |
Clorazepate | Clorazepate The therapeutic efficacy of Isoniazid can be decreased when used in combination with Clorazepic acid. |
Lorazepam | Lorazepam The therapeutic efficacy of Isoniazid can be decreased when used in combination with Lorazepam. |
Carmustine | Carmustine The metabolism of Carmustine can be decreased when combined with Isoniazid. |
Amantadine | Amantadine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Isoniazid. |
Codeine | Codeine The risk or severity of serotonin syndrome can be increased when Codeine is combined with Isoniazid. |
Tranylcypromine | Tranylcypromine The risk or severity of serotonin syndrome can be increased when Tranylcypromine is combined with Isoniazid. |
Phenelzine | Phenelzine The risk or severity of serotonin syndrome can be increased when Phenelzine is combined with Isoniazid. |
Procarbazine | Procarbazine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Procarbazine. |
Ergoloid Mesylates | Ergoloid Mesylates The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Ergoloid mesylate. |
Tetracycline | Tetracycline Tetracycline may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Minocycline | Minocycline The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Minocycline. |
Prochlorperazine | Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Isoniazid. |
Thioridazine | Thioridazine The metabolism of Thioridazine can be decreased when combined with Isoniazid. |
Trifluoperazine | Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Isoniazid. |
Bleomycin | Bleomycin Bleomycin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Dapsone | Dapsone The metabolism of Dapsone can be decreased when combined with Isoniazid. |
Sulfadiazine | Sulfadiazine Sulfadiazine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Oxycodone | Oxycodone The risk or severity of serotonin syndrome can be increased when Oxycodone is combined with Isoniazid. |
Methadone | Methadone The metabolism of Methadone can be decreased when combined with Isoniazid. |
Benztropine | Benztropine Benzatropine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Maprotiline | Maprotiline The metabolism of Maprotiline can be decreased when combined with Isoniazid. |
Ibuprofen | Ibuprofen Ibuprofen may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Perphenazine | Perphenazine The metabolism of Perphenazine can be decreased when combined with Isoniazid. |
Azathioprine | Azathioprine The metabolism of Azathioprine can be decreased when combined with Isoniazid. |
Phentermine | Phentermine The risk or severity of serotonin syndrome can be increased when Phentermine is combined with Isoniazid. |
Methylphenidate | Methylphenidate Methylphenidate may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Amoxapine | Amoxapine The risk or severity of serotonin syndrome can be increased when Amoxapine is combined with Isoniazid. |
Sulfasalazine | Sulfasalazine Sulfasalazine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Hydrocortisone | Hydrocortisone The serum concentration of Isoniazid can be decreased when it is combined with Hydrocortisone. |
Doxorubicin | Doxorubicin The metabolism of Doxorubicin can be decreased when combined with Isoniazid. |
Cytarabine | Cytarabine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Cytarabine. |
Phenazopyridine | Phenazopyridine Phenazopyridine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Carbamazepine | Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Isoniazid. |
Methyldopa | Methyldopa The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Methyldopa. |
Clonidine | Clonidine The metabolism of Clonidine can be decreased when combined with Isoniazid. |
Hydralazine | Hydralazine Isoniazid may decrease the excretion rate of Hydralazine which could result in a higher serum level. |
Cimetidine | Cimetidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cimetidine is combined with Isoniazid. |
Gentamicin Injection | Gentamicin Injection Gentamicin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Warfarin | Warfarin The serum concentration of Warfarin can be increased when it is combined with Isoniazid. |
Clonazepam | Clonazepam The therapeutic efficacy of Clonazepam can be decreased when used in combination with Isoniazid. |
Promethazine | Promethazine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Promethazine. |
Meclofenamate | Meclofenamate Meclofenamic acid may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Nitrofurantoin | Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Digoxin | Digoxin Isoniazid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Loxapine | Loxapine The risk or severity of serotonin syndrome can be increased when Loxapine is combined with Isoniazid. |
Chloroquine | Chloroquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Chloroquine is combined with Isoniazid. |
Quinine | Quinine The metabolism of Quinine can be decreased when combined with Isoniazid. |
Ethosuximide | Ethosuximide The metabolism of Ethosuximide can be decreased when combined with Isoniazid. |
Triamterene | Triamterene The metabolism of Triamterene can be decreased when combined with Isoniazid. |
Lactulose | Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Isoniazid. |
Chlorothiazide | Chlorothiazide Chlorothiazide may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Chlorthalidone | Chlorthalidone Chlorthalidone may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Metolazone | Metolazone Metolazone may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Isosorbide | Isosorbide Isosorbide may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Secobarbital | Secobarbital The therapeutic efficacy of Isoniazid can be decreased when used in combination with Secobarbital. |
Desipramine | Desipramine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Desipramine. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Isoniazid. |
Imipramine | Imipramine The metabolism of Imipramine can be decreased when combined with Isoniazid. |
Probenecid | Probenecid Isoniazid may decrease the excretion rate of Probenecid which could result in a higher serum level. |
Quinidine | Quinidine The metabolism of Quinidine can be decreased when combined with Isoniazid. |
Procainamide | Procainamide Isoniazid may decrease the excretion rate of Procainamide which could result in a higher serum level. |
Disopyramide | Disopyramide The metabolism of Isoniazid can be decreased when combined with Disopyramide. |
Valproic Acid | Valproic Acid The metabolism of Valproic acid can be decreased when combined with Isoniazid. |
Tamoxifen | Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Isoniazid. |
Butabarbital | Butabarbital Butabarbital may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Liothyronine | Liothyronine Liothyronine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Methimazole | Methimazole Methimazole may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Propylthiouracil | Propylthiouracil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Propylthiouracil is combined with Isoniazid. |
Chlorpropamide | Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Isoniazid. |
Tolbutamide | Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Isoniazid. |
Tolazamide | Tolazamide The metabolism of Tolazamide can be decreased when combined with Isoniazid. |
Dextromethorphan | Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Isoniazid. |
Cyclobenzaprine | Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Isoniazid. |
Niacin | Niacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Niacin is combined with Isoniazid. |
Baclofen | Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Isoniazid. |
Chlorpheniramine | Chlorpheniramine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Chlorpheniramine. |
Ethambutol | Ethambutol Ethambutol may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Methyclothiazide | Methyclothiazide Methyclothiazide may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Hydrochlorothiazide | Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Chlorzoxazone | Chlorzoxazone The metabolism of Isoniazid can be decreased when combined with Chlorzoxazone. |
Carisoprodol | Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Isoniazid. |
Folic Acid | Folic Acid Folic acid may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Disulfiram | Disulfiram The risk or severity of adverse effects can be increased when Disulfiram is combined with Isoniazid. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Isoniazid. |
Pseudoephedrine | Pseudoephedrine The risk or severity of serotonin syndrome can be increased when Pseudoephedrine is combined with Isoniazid. |
Nortriptyline | Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Isoniazid. |
Spironolactone | Spironolactone Spironolactone may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Amphotericin B Injection | Amphotericin B Injection Amphotericin B may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Mercaptopurine | Mercaptopurine The serum concentration of Mercaptopurine can be increased when it is combined with Isoniazid. |
Phytonadione | Phytonadione Isoniazid may decrease the excretion rate of Phylloquinone which could result in a higher serum level. |
Amikacin Injection | Amikacin Injection Amikacin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Nadolol | Nadolol Isoniazid may decrease the excretion rate of Nadolol which could result in a higher serum level. |
Butorphanol Injection | Butorphanol Injection The risk or severity of serotonin syndrome can be increased when Butorphanol is combined with Isoniazid. |
Nalbuphine Injection | Nalbuphine Injection The risk or severity of serotonin syndrome can be increased when Nalbuphine is combined with Isoniazid. |
Allopurinol | Allopurinol Allopurinol may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Flavoxate | Flavoxate Isoniazid may decrease the excretion rate of Flavoxate which could result in a higher serum level. |
Fluorouracil Injection | Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Isoniazid. |
Colchicine | Colchicine The metabolism of Colchicine can be decreased when combined with Isoniazid. |
Cefaclor | Cefaclor Cefaclor may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cefadroxil | Cefadroxil Cefadroxil may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection Cefazolin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cephalexin | Cephalexin Cephalexin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cefoxitin Injection | Cefoxitin Injection Cefoxitin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Dacarbazine | Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Isoniazid. |
Acetazolamide | Acetazolamide Isoniazid may increase the excretion rate of Acetazolamide which could result in a lower serum level and potentially a reduction in efficacy. |
Cefotaxime Injection | Cefotaxime Injection Cefotaxime may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Ketoconazole | Ketoconazole The serum concentration of Ketoconazole can be decreased when it is combined with Isoniazid. |
Pyrantel | Pyrantel Isoniazid may decrease the excretion rate of Pyrantel which could result in a higher serum level. |
Thiotepa Injection | Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Isoniazid. |
Vincristine Injection | Vincristine Injection The metabolism of Isoniazid can be decreased when combined with Vincristine. |
Captopril | Captopril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Captopril. |
Vinblastine | Vinblastine The metabolism of Vinblastine can be decreased when combined with Isoniazid. |
Ethacrynic Acid | Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Colistimethate Injection | Colistimethate Injection Colistimethate may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Metoprolol | Metoprolol The metabolism of Isoniazid can be decreased when combined with Metoprolol. |
Thiothixene | Thiothixene The metabolism of Thiothixene can be decreased when combined with Isoniazid. |
Aspirin | Aspirin Acetylsalicylic acid may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Salsalate | Salsalate Salsalate may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Alprazolam | Alprazolam The metabolism of Alprazolam can be decreased when combined with Isoniazid. |
Temazepam | Temazepam Temazepam may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Triazolam | Triazolam The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Triazolam is combined with Isoniazid. |
Dicyclomine | Dicyclomine Dicyclomine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Propantheline | Propantheline Propantheline may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Trimethoprim | Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Isoniazid. |
Diltiazem | Diltiazem The metabolism of Diltiazem can be decreased when combined with Isoniazid. |
Nifedipine | Nifedipine The metabolism of Nifedipine can be decreased when combined with Isoniazid. |
Timolol | Timolol The metabolism of Timolol can be decreased when combined with Isoniazid. |
Verapamil | Verapamil The metabolism of Verapamil can be decreased when combined with Isoniazid. |
Pindolol | Pindolol The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Pindolol. |
Cisplatin Injection | Cisplatin Injection Isoniazid may decrease the excretion rate of Cisplatin which could result in a higher serum level. |
Diflunisal | Diflunisal Diflunisal may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Piroxicam | Piroxicam Piroxicam may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Bumetanide | Bumetanide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Bumetanide is combined with Isoniazid. |
Etoposide | Etoposide The metabolism of Etoposide can be decreased when combined with Isoniazid. |
Glyburide | Glyburide The therapeutic efficacy of Glyburide can be decreased when used in combination with Isoniazid. |
Glipizide | Glipizide The metabolism of Glipizide can be decreased when combined with Isoniazid. |
Indapamide | Indapamide Indapamide may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Amoxicillin | Amoxicillin Isoniazid may decrease the excretion rate of Amoxicillin which could result in a higher serum level. |
Oxacillin Injection | Oxacillin Injection Oxacillin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Pentoxifylline | Pentoxifylline The serum concentration of Pentoxifylline can be increased when it is combined with Isoniazid. |
Pentamidine Injection | Pentamidine Injection Pentamidine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Ceftriaxone Injection | Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Labetalol | Labetalol The metabolism of Isoniazid can be decreased when combined with Labetalol. |
Auranofin | Auranofin Isoniazid may decrease the excretion rate of Auranofin which could result in a higher serum level. |
Leuprolide Injection | Leuprolide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Isoniazid. |
Gemfibrozil | Gemfibrozil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Gemfibrozil. |
Guanabenz | Guanabenz The metabolism of Guanabenz can be decreased when combined with Isoniazid. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Ceftazidime Injection | Ceftazidime Injection Ceftazidime may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Ketoprofen | Ketoprofen Ketoprofen may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cefotetan Injection | Cefotetan Injection Cefotetan may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Pimozide | Pimozide The metabolism of Pimozide can be decreased when combined with Isoniazid. |
Enalapril | Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Enalapril is combined with Isoniazid. |
Flurbiprofen | Flurbiprofen Flurbiprofen may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Amiodarone | Amiodarone The metabolism of Amiodarone can be decreased when combined with Isoniazid. |
Aztreonam Injection | Aztreonam Injection Aztreonam may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Buspirone | Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Isoniazid. |
Lovastatin | Lovastatin The metabolism of Lovastatin can be decreased when combined with Isoniazid. |
Ciprofloxacin | Ciprofloxacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ciprofloxacin is combined with Isoniazid. |
Mesalamine | Mesalamine Mesalazine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Diclofenac | Diclofenac The metabolism of Diclofenac can be decreased when combined with Isoniazid. |
Fluoxetine | Fluoxetine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Fluoxetine. |
Clozapine | Clozapine The metabolism of Isoniazid can be decreased when combined with Clozapine. |
Estazolam | Estazolam The therapeutic efficacy of Estazolam can be decreased when used in combination with Isoniazid. |
Idarubicin | Idarubicin The metabolism of Idarubicin can be decreased when combined with Isoniazid. |
Ofloxacin | Ofloxacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Ofloxacin. |
Didanosine | Didanosine Didanosine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Pentostatin Injection | Pentostatin Injection Pentostatin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Etodolac | Etodolac Etodolac may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Fosinopril | Fosinopril Fosinopril may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Nabumetone | Nabumetone Nabumetone may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Pravastatin | Pravastatin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pravastatin is combined with Isoniazid. |
Simvastatin | Simvastatin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Simvastatin is combined with Isoniazid. |
Teniposide Injection | Teniposide Injection The metabolism of Teniposide can be decreased when combined with Isoniazid. |
Itraconazole | Itraconazole The serum concentration of Itraconazole can be decreased when it is combined with Isoniazid. |
Lisinopril | Lisinopril Lisinopril may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Oxaprozin | Oxaprozin Oxaprozin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Rifabutin | Rifabutin Rifabutin may increase the hepatotoxic activities of Isoniazid. |
Bisoprolol | Bisoprolol Bisoprolol may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Zolpidem | Zolpidem The metabolism of Zolpidem can be decreased when combined with Isoniazid. |
Doxazosin | Doxazosin The metabolism of Doxazosin can be decreased when combined with Isoniazid. |
Isradipine | Isradipine Isradipine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Omeprazole | Omeprazole The metabolism of Omeprazole can be decreased when combined with Isoniazid. |
Cisapride | Cisapride The metabolism of Cisapride can be decreased when combined with Isoniazid. |
Gabapentin | Gabapentin The therapeutic efficacy of Gabapentin can be decreased when used in combination with Isoniazid. |
Fluvastatin | Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Isoniazid. |
Venlafaxine | Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Isoniazid. |
Nizatidine | Nizatidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nizatidine is combined with Isoniazid. |
Stavudine | Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Stavudine is combined with Isoniazid. |
Famciclovir | Famciclovir The metabolism of Famciclovir can be decreased when combined with Isoniazid. |
Fluvoxamine | Fluvoxamine The metabolism of Fluvoxamine can be decreased when combined with Isoniazid. |
Nefazodone | Nefazodone The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Nefazodone. |
Lamotrigine | Lamotrigine The therapeutic efficacy of Isoniazid can be decreased when used in combination with Lamotrigine. |
Losartan | Losartan The metabolism of Losartan can be decreased when combined with Isoniazid. |
Valacyclovir | Valacyclovir Valaciclovir may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Tramadol | Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Isoniazid. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Vinorelbine can be decreased when combined with Isoniazid. |
Carboplatin Injection | Carboplatin Injection Carboplatin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Lansoprazole | Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Isoniazid. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Isoniazid. |
Bupropion | Bupropion The risk or severity of seizure can be increased when Isoniazid is combined with Bupropion. |
Ticlopidine | Ticlopidine The metabolism of Isoniazid can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Saquinavir. |
Metformin | Metformin Metformin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Nisoldipine | Nisoldipine Nisoldipine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Lamivudine | Lamivudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Lamivudine is combined with Isoniazid. |
Riluzole | Riluzole The metabolism of Riluzole can be decreased when combined with Isoniazid. |
Acarbose | Acarbose Acarbose may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Glimepiride | Glimepiride The metabolism of Glimepiride can be decreased when combined with Isoniazid. |
Gemcitabine Injection | Gemcitabine Injection Gemcitabine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Indinavir | Indinavir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Isoniazid. |
Ritonavir | Ritonavir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Isoniazid. |
Docetaxel Injection | Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Isoniazid. |
Cidofovir Injection | Cidofovir Injection Cidofovir may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Meropenem Injection | Meropenem Injection Meropenem may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be decreased when combined with Isoniazid. |
Zafirlukast | Zafirlukast The metabolism of Zafirlukast can be decreased when combined with Isoniazid. |
Fosfomycin | Fosfomycin Fosfomycin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Mirtazapine | Mirtazapine Isoniazid may increase the serotonergic activities of Mirtazapine. |
Topiramate | Topiramate The therapeutic efficacy of Isoniazid can be decreased when used in combination with Topiramate. |
Zileuton | Zileuton The metabolism of Zileuton can be decreased when combined with Isoniazid. |
Valsartan | Valsartan The metabolism of Valsartan can be decreased when combined with Isoniazid. |
Pramipexole | Pramipexole Pramipexole may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Donepezil | Donepezil The metabolism of Donepezil can be decreased when combined with Isoniazid. |
Azithromycin | Azithromycin The metabolism of Azithromycin can be decreased when combined with Isoniazid. |
Carvedilol | Carvedilol The metabolism of Carvedilol can be decreased when combined with Isoniazid. |
Nilutamide | Nilutamide Nilutamide may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Flutamide | Flutamide The metabolism of Isoniazid can be decreased when combined with Flutamide. |
Selegiline | Selegiline The metabolism of Selegiline can be decreased when combined with Isoniazid. |
Bicalutamide | Bicalutamide The metabolism of Bicalutamide can be decreased when combined with Isoniazid. |
Sertraline | Sertraline The metabolism of Sertraline can be decreased when combined with Isoniazid. |
Propafenone | Propafenone The metabolism of Propafenone can be decreased when combined with Isoniazid. |
Letrozole | Letrozole The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isoniazid is combined with Letrozole. |
Irbesartan | Irbesartan The metabolism of Irbesartan can be decreased when combined with Isoniazid. |
Tamsulosin | Tamsulosin Tamsulosin may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Ropinirole | Ropinirole The risk or severity of adverse effects can be increased when Isoniazid is combined with Ropinirole. |
Quetiapine | Quetiapine The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Quetiapine. |
Cefepime Injection | Cefepime Injection Cefepime may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cefprozil | Cefprozil Cefprozil may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cefpodoxime | Cefpodoxime Cefpodoxime may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Cetirizine | Cetirizine Cetirizine may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Paroxetine | Paroxetine The metabolism of Paroxetine can be decreased when combined with Isoniazid. |
Tolcapone | Tolcapone Tolcapone may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Citalopram | Citalopram The serum concentration of Citalopram can be increased when it is combined with Isoniazid. |
Capecitabine | Capecitabine The metabolism of Capecitabine can be decreased when combined with Isoniazid. |
Efavirenz | Efavirenz The metabolism of Efavirenz can be decreased when combined with Isoniazid. |
Abacavir | Abacavir Isoniazid may decrease the excretion rate of Abacavir which could result in a higher serum level. |
Sildenafil | Sildenafil The metabolism of Sildenafil can be decreased when combined with Isoniazid. |
Celecoxib | Celecoxib Celecoxib may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Rosiglitazone | Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Isoniazid. |
Tolterodine | Tolterodine The metabolism of Tolterodine can be decreased when combined with Isoniazid. |
Thalidomide | Thalidomide The metabolism of Thalidomide can be decreased when combined with Isoniazid. |
Oseltamivir | Oseltamivir Oseltamivir may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Balsalazide | Balsalazide Balsalazide may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Nateglinide | Nateglinide The metabolism of Isoniazid can be decreased when combined with Nateglinide. |
Levetiracetam | Levetiracetam The therapeutic efficacy of Levetiracetam can be decreased when used in combination with Isoniazid. |
Rabeprazole | Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Isoniazid. |
Terbinafine | Terbinafine The metabolism of Terbinafine can be decreased when combined with Isoniazid. |
* This branded product is no longer on the market. Generic alternatives may be available.
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists