Systane Nighttime mineral oil and white petrolatum 30 mg/g; 940 mg/g Ointment, 1 tube — NDC 0065-0509-35 (Billing 00065-0509-35)
This is a package of 1 tube of Systane Nighttime mineral oil and white petrolatum 30 mg/g; 940 mg/g Ointment from Alcon Laboratories, Inc., marketed since Jun 2008 and currently FDA-listed; retail pharmacies pay about $2.48 per g (NADAC). It is this product's only package size.
NDC database record
One package, one record: these facts belong to NDC 0065-0509-35 alone.
- Record
- FDA NDC Directory package listing · Human OTC drug
- Code segments
- 0065 labeler · 0509 product · 35 package
- Package marketed since
- Jun 26, 2008
- Sample package
- No — commercial package
- Listing certified through
- Dec 31, 2026
- Barcode (UPC)
- 0300650509350
- Medicaid fills, this package
- 26,682 prescriptions in the last four reported quarters
- FDA record last changed
- Jul 24, 2026
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification
- GSN (GCN sequence number): 064246
- GCN: 99952
- GPI-14 (Medi-Span): 86209902904220
- HICL (First Databank): 002215
- AHFS class code: 52:92.00.00
- RxCUI (RxNorm): 706820
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 5, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 1, 2026
RxNorm drug class
This medicine belongs to the Softeners, emollients class.
Where does this data come from?
- RxClass (NLM) · catalog refreshed Oct 1, 2026
Clinical
Systane Nighttime is an over-the-counter eye ointment marketed under FDA's OTC drug rules for its category. It contains mineral oil and white petrolatum, which are occlusive lubricants commonly used in nighttime eye products to coat and protect the eye surface. These ingredients are typically used to soothe dry eye discomfort and help retain moisture on the eye overnight.
Patient education
Supplement & herbal interactions
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 5, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $2.485 | $8.70 / 3.5 g |
| Medicaid paysCMS SDUD · 12 mo | $4.08 | $14.29 / 3.5 g |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
- CMS NADAC weekly file · file of Aug 26, 2026
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · through Q1 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Marketing end | Status |
|---|---|---|---|---|
| 00065-0509-35 You're viewing this Main listing | 1 TUBE in 1 CARTON / 3.5 g in 1 TUBE | 2008-06-26 | — | Active |
Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| GenTeal Tears NIGHT-TIME .03 g/g; .94 g/g 00065-0518-01 | Alcon | 1 tube | $2.480 | — | Availability likely | +0% |
| Systane Nighttime 30 mg/g; 940 mg/gthis 00065-0509-35 | Alcon | 1 tube | $2.485 | — | Availability likely | — |
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA Orange Book · refreshed Oct 3, 2026
- CMS NADAC weekly file · file of Aug 26, 2026
Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
- FDA Orange Book · refreshed Oct 3, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII 7EV65EAW6H
Lanolin is a waxy substance derived from sheep's wool. It's used in medicines as an emollient and skin-conditioning agent to soften formulations and improve spreadability in topical products like creams and ointments.
1 inactive ingredient listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.- FDA label on DailyMed · label index refreshed Oct 5, 2026
- FDA openFDA NDC Directory · synced Oct 1, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
More NDCs from Alcon Laboratories, Inc. labeler code 00065
- GenTeal Tears (Moderate) Dextran 70, Glycerin, Hypromellose 70 1 mg/mL; 2 mg/mL; 3 mg/mL Solution/ Drops NDC 0065-0426-36
- Systane Lubricant polyethylene glycol 400 and Propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops NDC 0065-0429-15
- Systane polyethylene glycol and propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops NDC 0065-0431-33
- Systane polyethylene glycol 400 and propylene 400 4 mg/mL; 3 mg/mL Gel NDC 0065-0454-07
- Systane hypromellose 2910 (4000 MPA.S) 3 mg/g Gel NDC 0065-0474-01
- Systane COMPLETE propylene glycol .06 mg/mL Emulsion NDC 0065-0481-01
- GenTeal Tears NIGHT-TIME mineral oil, white petrolatum .03 g/g; .94 g/g Ointment NDC 0065-0518-01
- Tetracaine Hydrochloride 5 mg/mL Solution NDC 0065-0741-14
- BSS balanced salt solution 6.4 mg/mL; .75 mg/mL; .48 mg/mL; .3 mg/mL; 3.9 mg/mL; 1.7 mg/mL Solution NDC 0065-0795-15
- BSS PLUS balanced salt solution enriched with bicarbonate, dextrose, and glutathione Kit NDC 0065-0800-50
- PATADAY ONCE DAILY RELIEF OLOPATADINE HYDROCHLORIDE 7 mg/mL Solution NDC 0065-0816-01
- atropine sulfate 10 mg/mL Solution NDC 0065-0817-01
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses for the temporary relief of burning and irritation due to dryness of the eye for use as a lubricant to prevent further irritation or to relieve dryness of the eye
⏱️ Dosage and Administration ▾
Directions Pull down the lower lid of the affected eye and apply a small amount (one-fourth inch) of ointment to the inside of the eyelid.
⚠️ Warnings ▾
Warnings For external use only Do not use if you are sensitive to any ingredient in this product
🧪 Inactive Ingredients ▾
Inactive ingredient anhydrous liquid lanolin 3%
🎯 Purpose ▾
Active ingredients Purpose Mineral Oil 3% Lubricant White Petrolatum 94% Lubricant
📄 When Using This Product ▾
When using this product remove contact lenses before using do not touch tip of container to any surface to avoid contamination replace cap after each use
📄 Stop Use and Ask a Doctor If ▾
Stop use and ask a doctor if you are experiencing any of the following: eye pain changes in vision continued redness or irritation of the eye condition worsens or persist for more than 72 hours
📄 Keep Out of Reach of Children ▾
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
📄 Other Information ▾
Other information Not for use with contact lenses Store at 8° - 27° C (46° - 80° F)
📄 Questions or Comments ▾
Questions? In the U.S. call 1-800-757-9195 [email protected] www.systane.com
📄 Package Label / Principal Display Panel ▾
PRINCIPAL DISPLAY PANEL Systane ® LUBRICANT EYE OINTMENT NIGHTTIME SEVERE DRY EYE RELIEF For nighttime protection from further irritation Systane ® LUBRICANT EYE OINTMENT NIGHTTIME SEVERE DRY EYE RELIEF #1 DOCTOR RECOMMENDED BRAND 1 Intensive relief Preservative free OINTMENT Alcon STERILE 3.5 g Tube (1/8 OZ NET WT) TAMPER EVIDENT: For your protection, do not use if carton security seal is damaged or missing at the time of purchase. 1 Based on a survey of eye care professionals. Data on file.
1635970-0623 LOT: EXP.: Systane ® LUBRICANT EYE OINTMENT Alcon Made in Belgium ALCON LABORATORIES, INC. Fort Worth, Texas 76134 USA Systane® LUBRICANT EYE OINTMENT NIGHTTIME SEVERE DRY EYE RELIEF For nighttime protection from further irritation Systane ® LUBRICANT EYE OINTMENT NIGHTTIME SEVERE DRY EYE RELIEF #1 DOCTOR RECOMMENDED BRAND 1 Intensive relief Preservative free OINTMENT Alcon STERILE 3.5 g Tube (1/8 OZ NET WT) TAMPER EVIDENT: For your protection, do not use if carton security seal is damaged or missing at the time of purchase.
1 Based on a survey of eye care professionals. Data on file. 3601179 01-1024 Systane® LUBRICANT EYE OINTMENT Alcon Made in Spain ALCON LABORATORIES, INC.
Fort Worth, Texas 76134 USA