good sense anti diarrheal anti gas loperamide hydrochloride, simethicone 2 mg; 125 mg Tablet, 30-count
by L. Perrigo Company · 1 BOTTLE in 1 CARTON (0113-0087-65) / 30 TABLET in 1 BOTTLE
NDC 00113-0087-65
🏷️ FDA NDC (as labeled)
0113-0087-65
billing pads the labeler segment with a zero
This package
OTC
Generic
Discontinued
Non-controlled
⚠ Discontinued by firm
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
⚠️
Excluded from the active FDA NDC Directory.
The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory.
Search the FDA NDC Directory ↗
🆔 Identity & classification
FDA NDC (as labeled)
0113-0087-65
Product NDC
0113-0087
11-digit billing NDC
00113008765
NCPDP billing unit
EA — each (per item)
RxCUI
978001
UNII
77TI35393C, 92RU3N3Y1O
Application #
ANDA209837
SPL Set ID
2cda08a8-3f5e-430c-84a3-d29b97d647af
Physiologic effect
Skin Barrier Activity
DEA schedule
Non-controlled
Marketing category
ANDA
Marketing status
Discontinued
FDA listing status
Discontinued by firm
Marketing start
2018-10-11
Route
ORAL
Dosage form
TABLET
Substance
LOPERAMIDE HYDROCHLORIDE; DIMETHICONE
GPI-14
47991002080320
GPI class
GoodSense Anti-Diarr/Ant-Gas
GCN Seq No
048990
GCN
14984
HICL code
015777
Ingredient (HICL)
Loperamide Hcl/Simethicone
HIC1 code
D
Therapeutic class — broad (HIC1)
Biliary System/Gastro-Intestinal System
HIC2 code
D6
Therapeutic class — intermediate (HIC2)
Drugs Acting Principally On The Colon
HIC3 code
D6D
Therapeutic class — specific (HIC3)
Antidiarrheals
AHFS code
56:08.00.00
AHFS class
Antidiarrhea Agents
FDB label name
GS ANTI-DIARRHEAL-ANTIGAS CPLT
FDB brand name
Anti-Diarrheal-Anti-Gas
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 0113-0087-65 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00113-0087-65. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Opioid Agonist class.
Pharmacologic class
Opioid Agonist
Drug family (ATC)
Antipropulsives
How it works
Opioid Agonists
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerL. Perrigo Company
Application holderPERRIGO R AND D CO
FDA applicationANDA209837 (ANDA)
Labeler code00113
First marketedOct 2018
Product typeHuman Otc Drug
Portfolio228 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name GS ANTI-DIARRHEAL-ANTIGAS CPLT Ingredient Loperamide Hcl/Simethicone
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about loperamide hydrochloride, simethicone?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Color
White
ShapeOval
ImprintL0R1;2;125
Size17 mm
ScoringScored — splits in 2
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per ea | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.294 | $8.81 / 30 tablets |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per ea) — tap or hover for the price & month
▼ Down 6% over the last 9 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| good neighbor pharmacy anti diarrheal anti gas 2 mg/1; 125 mg 46122-0620-62 | Amerisource | 24 tablets | $0.286 | — | Availability likely | save 3% |
| foster and thrive anti diarrheal anti gas 2 mg/1; 125 mg 70677-1105-01 | Strategic | 12 tablets | $0.286 | — | Availability likely | save 3% |
| good sense anti diarrheal anti gas 2 mg/1; 125 mgthis 00113-0087-65 | L. | 30 tablets | $0.293 | — | Discontinued | — |
| Good Sense Anti Diarrheal Anti Gas 2 mg/1; 125 mg 00113-1087-89 | L. | 18 tablets | — | — | FDA listed | — |
| anti diarrheal and anti gas 2 mg/1; 125 mg 00363-1830-53 | Walgreen | 12 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 00363-9606-75 | WALGREEN | 12 tablets | — | — | FDA listed | — |
| up and up anti diarrheal anti gas 2 mg/1; 125 mg 11673-0646-62 | Target | 24 tablets | — | — | FDA listed | — |
| signature care anti diarrheal anti gas 2 mg/1; 125 mg 21130-0183-62 | Safeway | 24 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 21130-0222-24 | Better | 24 tablets | — | — | FDA listed | — |
| Anti Diarrheal Anti Gas 2 mg/1; 125 mg 30142-0581-53 | Kroger | 12 tablets | — | — | FDA listed | — |
| anti diarrheal anti gas 2 mg/1; 125 mg 37808-0714-53 | H | 12 tablets | — | — | FDA listed | — |
| equaline anti diarrheal plus anti gas 2 mg/1; 125 mg 41163-0553-89 | United | 18 tablets | — | — | FDA listed | — |
| anti diarrheal plus anti gas 2 mg/1; 125 mg 41250-0375-55 | Meijer | 42 tablets | — | — | Discontinued | — |
| CareOne Diarrhea and Gas Control 2 mg/1; 125 mg 41520-0772-53 | American | 12 tablets | — | — | FDA listed | — |
| anti diarrheal anti gas 2 mg/1; 125 mg 42507-0699-53 | HyVee | 12 tablets | — | — | FDA listed | — |
| IMODIUM Multi-Symptom Relief 2 mg/1; 125 mg 50580-0338-12 | Kenvue | 12 tablets | — | — | FDA listed | — |
| Loperamide HCl and Simethicone 2 mg/1; 125 mg 51660-0069-06 | Ohm | 6 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride, Simethicone 2 mg/1; 125 mg 53041-0263-50 | Guardian | 6 tablets | — | — | FDA listed | — |
| Anti-Diarrheal/Anti-Gas 2 mg/1; 125 mg 53943-0263-33 | Discount | 24 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 55319-0052-75 | Family | 12 tablets | — | — | FDA listed | — |
| dg health anti diarrheal anti gas 2 mg/1; 125 mg 55910-0383-53 | Dolgencorp, | 12 tablets | — | — | FDA listed | — |
| antidiarrheal multi symptom relief 125 mg/1; 2 mg 56062-0511-62 | Publix | 24 tablets | — | — | Discontinued | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 58602-0815-74 | Aurohealth | 6 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 58602-0868-76 | Aurohealth | 24 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 58602-0869-76 | Aurohealth | 24 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 62207-0739-69 | Granules | 12 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 69230-0325-04 | Camber | 4 tablets | — | — | FDA listed | — |
| Anti-Diarrheal/Anti-Gas 2 mg/1; 125 mg 69256-0265-31 | Harris | 12 tablets | — | — | FDA listed | — |
| Loperamide hydrochloride and Simethicone 2 mg/1; 125 mg 69452-0210-04 | Bionpharma | 6 tablets | — | — | FDA listed | — |
| Loperamide hydrochloride and Simethicone 2 mg/1; 125 mg 69452-0531-12 | Bionpharma | 24 tablets | — | — | FDA listed | — |
| anti diarrheal and anti gas 2 mg/1; 125 mg 69842-0644-53 | CVS | 12 tablets | — | — | FDA listed | — |
| Basic Care Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 72288-0001-62 | Amazon.com | 24 tablets | — | — | FDA listed | — |
| Anti-Diarrheal/Anti-Gas Caplets 2 mg/1; 125 mg 73581-0178-24 | YYBA | 24 tablets | — | — | FDA listed | — |
| Anti-Diarrheal/Anti-Gas Multi-Symptom Relief 2 mg/1; 125 mg 79903-0116-33 | Wal-Mart | 24 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 79903-0223-12 | WALMART | 12 tablets | — | — | FDA listed | — |
| Equate Anti Diarrheal Anti Gas Multi-Symptom Relief 2 mg/1; 125 mg 79903-0302-12 | WALMART | 12 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 80136-0384-24 | NORTHEAST | 24 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 2 mg/1; 125 mg 81522-0325-24 | FSA | 24 tablets | — | — | FDA listed | — |
| Loperamide Hydrochloride and Simethicone 125 mg/1; 2 mg 84441-0713-10 | IMO-GEN | 100 tablets | — | — | FDA listed | — |
| anti diarrheal anti gas 2 mg/1; 125 mg 11822-1003-01 | Rite | 42 tablets | — | — | Discontinued | — |
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2018
On the market since
Oct 2018
📍
2026
Currently FDA-listed
8 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug
This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Good Sense Anti Diarrheal Anti Gas (this brand).
Top reported reactions
Reporter sex
Male · 100%
Serious outcomes
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Status |
|---|---|---|---|---|---|
| 00113-0087-53 | 12 BLISTER PACK in 1 CARTON (0113-0087-53) / 1 TABLET in 1 BLISTER PACK | $0.2857 / ea | $3.43 | 2018-10-11 | Active |
| 00113-0087-62 | 24 BLISTER PACK in 1 CARTON (0113-0087-62) / 1 TABLET in 1 BLISTER PACK | $0.2857 / ea | $6.86 | 2019-06-10 | Active |
| 00113-0087-65 You're viewing this | 1 BOTTLE in 1 CARTON (0113-0087-65) / 30 TABLET in 1 BOTTLE | $0.2935 / ea | $8.80 | 2018-10-16 | Discontinued by firm |
Per ea, this pack runs about 3% above the cheapest pack (NDC 00113-0087-53, $0.2857 vs $0.2935 NADAC).
Pack size FAQ
What quantity is in NDC 00113-0087-65?
NDC 00113-0087-65 is a 30-count package — 1 bottle in 1 carton / 30 tablet in 1 bottle.
What is the difference between NDC 00113-0087-65 and NDC 00113-0087-53?
Both are good sense anti diarrheal anti gas loperamide hydrochloride, simethicone 2 mg; 125 mg Tablet — the drug itself is identical. NDC 00113-0087-65 is the 30-count package, while NDC 00113-0087-53 is the 12 tablets package. Per-ea NADAC also differs: $0.2935 here vs $0.2857 for the 12 tablets pack.
What NDC number is used to bill for this package of good sense anti diarrheal anti gas loperamide hydrochloride, simethicone 2 mg; 125 mg Tablet?
Bill NDC 00113-0087-65 — the 11-digit billing format is 00113008765. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available. |
| NADAC pharmacy acquisition price (CMS) | ✓ Available |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 0113-0087-65, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 00113-0087-65, written without dashes as 00113008765. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 00113-0087-65, the first segment (00113) is the labeler code FDA assigned to L. Perrigo Company; the middle segment (0087) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (65) identifies this exact package size and type. Together they name one specific package of one specific product.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 12 tablets (00113-0087-53), 24 tablets (00113-0087-62). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
L. Perrigo Company is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses relieves symptoms of diarrhea plus bloating, pressure and cramps, commonly referred to as gas
⏱️ Dosage and Administration ▾
Directions • drink plenty of clear fluids to help prevent dehydration caused by diarrhea • take only on an empty stomach (1 hour before or 2 hours after a meal) • take with a full (8 oz.) glass of water • find right dose on chart below. If possible, use weight to dose; otherwise, use age. adults and children 12 years and over 2 caplets after the first loose stool; 1 caplet after each subsequent loose stool; but no more than 4 caplets in 24 hours children 9-11 years (60-95 lbs) 1 caplet after the first loose stool; ½ caplet after each subsequent loose stool; but no more than 3 caplets in 24 hours children 6-8 years (48-59 lbs) 1 caplet after the first loose stool; ½ caplet after each subsequent loose stool; but no more than 2 caplets in 24 hours children 2-5 years (34 to 47 lbs) ask a doctor children under 2 years (up to 33 lbs) do not use
⚠️ Warnings ▾
Warnings Allergy alert: Do not use if you have ever had a rash or other allergic reaction to loperamide HCl Heart alert: Taking more than directed can cause serious heart problems or death Do not use • if you have bloody or black stool • if you have difficulty swallowing Ask a doctor before use if you have • fever • mucus in the stool • a history of liver disease • a history of abnormal heart rhythm Ask a doctor or pharmacist before use if you are taking a prescription drug. Loperamide may interact with certain prescription drugs.
When using this product tiredness, drowsiness or dizziness may occur. Be careful when driving or operating machinery. Stop use and ask a doctor if • symptoms get worse • diarrhea lasts for more than 2 days • you get abdominal swelling or bulging.
These may be signs of a serious condition. • you have difficulty swallowing the caplet If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
(1-800-222-1222)
📦 Storage and Handling ▾
Other information • each caplet contains: calcium 165 mg, sodium 3 mg • store between 20 ° -25 ° C (68 ° -77 ° F). Protect from light. • do not use if printed blister unit is broken or torn
🧪 Active Ingredient ▾
Active ingredients (in each caplet) Loperamide HCl 2 mg Simethicone 125 mg
🧪 Inactive Ingredients ▾
Inactive ingredients acesulfame potassium, croscarmellose sodium, dibasic calcium phosphate, maltodextrin, microcrystalline cellulose, natural and artificial flavor, propylene glycol, stearic acid
🎯 Purpose ▾
Purposes Anti-diarrheal Anti-gas
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.