Cold Therapy Pain Relief Menthol, unspecified form 36 mg/mL Gel, 74 mL — NDC 0363-0356-25 (Billing 00363-0356-25)
This is a package of 74 mL of Cold Therapy Pain Relief Menthol, unspecified form 36 mg/mL Gel from Walgreen Co., marketed since Apr 2024 and currently FDA-listed.
NDC database record
One package, one record: these facts belong to NDC 0363-0356-25 alone.
- Record
- FDA NDC Directory package listing · Human OTC drug
- Code segments
- 0363 labeler · 0356 product · 25 package
- Package marketed since
- Apr 1, 2024
- Sample package
- No — commercial package
- Listing certified through
- Dec 31, 2026
- Barcode (UPC)
- 0311917046549, 0311917045993
- FDA record last changed
- Jul 24, 2026
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 8, 2026
- FDA label on DailyMed · label index refreshed Oct 8, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 8, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 8, 2026
Clinical
This is a topical gel containing menthol, an over-the-counter product sold under FDA's monograph rules for pain relief products. Menthol is typically used in topical formulas to produce a cooling sensation on the skin, which is commonly combined with other pain-relief approaches for muscle and joint discomfort. The gel form is applied directly to the area of concern on intact skin.
Patient education
Supplement & herbal interactions
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 8, 2026
- FDA label on DailyMed · label index refreshed Oct 8, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
- CMS NADAC weekly file
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · refreshed Oct 9, 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Marketing end | Status |
|---|---|---|---|---|
| 00363-0356-03 0363-0356-03 Main listing | 89 mL in 1 TUBE | 2024-04-01 | — | Active |
| 00363-0356-25 You're viewing this | 74 mL in 1 BOTTLE, WITH APPLICATOR | 2024-04-01 | — | Active |
You're viewing the smallest of 2 pack sizes for this product.
Pack size FAQ
What quantity is in this package?
How does this package differ from NDC 00363-0356-03?
What NDC number is used to bill for this package of Cold Therapy Pain Relief Menthol, unspecified form 36 mg/mL Gel?
Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Overnight Cold Therapy Pain Relief 36 mg/mL 00363-0355-03 | Walgreen | 89 ml | — | — | FDA listed | — |
| Cold Therapy Pain Relief 36 mg/mLthis 00363-0356-25 | Walgreen | 74 ml | — | — | FDA listed | — |
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 8, 2026
- FDA Orange Book · refreshed Oct 9, 2026
- CMS NADAC weekly file
Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
- FDA Orange Book · refreshed Oct 9, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII H4N855PNZ1
Alpha-tocopherol is a form of vitamin E, a fat-soluble antioxidant derived from natural or synthetic sources. In medicines, it prevents oils and fats from breaking down and becoming rancid, protecting the product's stability and shelf life.
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UNII ZY81Z83H0X
Aloe vera leaf is a plant extract derived from the aloe plant. It is used in medicines as a natural moisturizer and skin-soothing agent in topical formulations.
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UNII 597E9BI3Z3
Arctium lappa root is a plant-derived ingredient used in some traditional and herbal preparations. In formulations, it may serve as a natural extract or botanical agent to support product stability or flavor.
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UNII OZ0E5Y15PZ
A plant extract from arnica flowers, used as a flavoring agent or fragrance component in medicines. It may also provide mild soothing properties to certain topical formulations.
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UNII P0M7O4Y7YD
A plant extract from calendula flowers, traditionally used in formulations. It typically serves as a botanical ingredient that may provide color, fragrance, or skin-conditioning properties to topical products.
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UNII 5TJD82A1ET
A cooling crystalline substance made synthetically that is added to medicines as a fragrance, flavoring agent, and mild local irritant to produce a cooling or warming sensation on the skin or mucous membranes.
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UNII 4Q93RCW27E
A synthetic polymer made from acrylic acid that's crosslinked for stability. It acts as a thickener and gelling agent in creams and gels, helping the medicine spread evenly and maintain its texture.
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UNII H3R47K3TBD
FD&C Blue No. 1 is a synthetic blue dye approved for use in foods and medicines. It serves as a colorant to give the medication its distinctive appearance and help with product identification.
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UNII I753WB2F1M
FD&C Yellow No. 5 is a synthetic yellow colorant approved by the FDA. It is added to medicines to make pills, tablets, or liquids visually distinct and easier to identify.
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UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
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UNII W2ZU1RY8B0
A plant extract from green tea leaves. It's used as an antioxidant ingredient to help preserve the medicine and maintain its stability during storage.
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UNII 1Q953B4O4F
Ilex paraguariensis leaf, commonly known as yerba mate, is a plant extract used in medicines as a flavoring agent and to add botanical content. It may also contribute mild preservative properties to the formulation.
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UNII 4PW41QCO2M
Indian frankincense is a natural resin extracted from trees native to India. It is used in medicines as a binder and thickening agent to help hold ingredients together and improve texture.
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UNII ND2M416302
Isopropyl alcohol is a clear liquid solvent derived from petroleum. In medicines, it dissolves active ingredients and other components, helps the product flow smoothly, and aids in sterilization during manufacturing.
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UNII 0RE8K4LNJS
Isopropyl myristate is an oily liquid made from coconut or palm oil. It's used in medicines as an emollient and penetration enhancer to help the medicine absorb through skin or improve spreadability in topical products.
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UNII ETJ7Z6XBU4
Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
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UNII 9O3K93S3TK
Trolamine is an alkaline compound used as a pH buffer and emulsifier in medicines. It helps neutralize acids, stabilize formulations, and enable mixing of oil and water-based ingredients.
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UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
18 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.- FDA label on DailyMed · label index refreshed Oct 8, 2026
- FDA openFDA NDC Directory · synced Oct 8, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
More NDCs from Walgreen Co. labeler code 00363
- Mucus Relief Severe Congestion and Cough Maximum Strength dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride 20 mg/20mL; 400 mg/20mL; 10 mg/20mL Liquid NDC 0363-0337-06
- Acetaminophen 650 mg Tablet, Extended Release NDC 0363-0340-08
- Walgreens 40 Invisible Facial Sunscreen Broad Spectrum SPF 40 Avobenzone, Homosalate, Octisalate, Octocrylene 80 mg/mL; 30 mg/mL; 50 mg/mL; 40 mg/mL Gel NDC 0363-0349-09
- Itch Relief Gel Diphenhydramine HCl 2 mg/100mL Gel NDC 0363-0353-04
- Walgreen Itch Relief Gel Diphenhydramine Hydrochloride 20 mg/mL Gel NDC 0363-0354-04
- Overnight Cold Therapy Pain Relief Menthol, unspecified form 36 mg/mL Gel NDC 0363-0355-03
- Walgreens Eczema Relief HYDROCORTISONE ACETATE 10 mg/g Cream NDC 0363-0357-02
- No Mess Hydrocortisone Applicator 10 mg/mL Liquid NDC 0363-0358-12
- Esomeprazole Magnesium 20 mg Tablet, Delayed Release NDC 0363-0361-42
- Hydrocortisone Cool Relief gel with Aloe 1 g/100g Gel NDC 0363-0363-01
- Walgreens Broad Spectrum SPF 40 Radiant Facial Sunscreen AVOBENZONE, OCTISALATE, OCTOCRYLENE 30 mg/mL; 50 mg/mL; 100 mg/mL Cream NDC 0363-0364-17
- Walgreens Broad Spectrum SPF 50 Body Oil Sunscreen Avobenzone, Homosalate, Octisalate, Octocrylene 30 mg/mL; 150 mg/mL; 50 mg/mL; 100 mg/mL Spray NDC 0363-0366-21
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 8, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses Temporarily relieves minor aches and pains of muscles and joints associated with simple backache arthritis strains bruises sprains
⏱️ Dosage and Administration ▾
Directions adults and children 2 years of age and older: rub a thin film over affected area not more than 3 to 4 times daily children under 2 years of age: consult a physician wash hands after use with cool water
⚠️ Warnings ▾
Warnings For external use only. Flammable: Keep away from excessive heat or open flame. When using this product use only as directed avoid contact with the eyes or on mucous membranes do not apply to wounds or damaged skin do not apply to irritated skin or if excessive irritation develops do not bandage tightly or use with heating pad or device Stop use and ask a doctor if you experience pain, swelling or blistering oi the skin condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days arthritic pain persists for more than 10 days, or redness is present, or in conditions affecting children under 12 years of age If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
🧪 Active Ingredient ▾
Active ingredient Menthol 4%
🧪 Inactive Ingredients ▾
Inactive ingredients Aloe Barbadensis Leaf Extract, Arctium Lappa Root Extract, Arnica Montana (Arnica Flower) Extract, Boswellia Serrata Extract, Calendula Officinalis (Calendula) Flower Extract, Camellia Sinensis (Green Tea) Extract, Camphor, Caprylic/Capric Triglyceride, Carbomer, FD&C Blue #1, FD&C Yellow #5, Glycerin, Isopropyl Alcohol, Isopropyl Myristate, Organic Ilex Paraguanensis Leaf Extract, Tocopheryl Acetate, Triethanolamine, Silicone Dioxide, Water.
🎯 Purpose ▾
Purpose Topical Analgesic
📄 When Using This Product ▾
When using this product use only as directed avoid contact with the eyes or on mucous membranes do not apply to wounds or damaged skin do not apply to irritated skin or if excessive irritation develops do not bandage tightly or use with heating pad or device
📄 Stop Use and Ask a Doctor If ▾
Stop use and ask a doctor if you experience pain, swelling or blistering oi the skin condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days arthritic pain persists for more than 10 days, or redness is present, or in conditions affecting children under 12 years of age
🤰 If Pregnant or Breast-Feeding ▾
If pregnant or breast-feeding, ask a health professional before use.
📄 Keep Out of Reach of Children ▾
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
📄 Other Information ▾
Other information store at 20-25°C (68-77°F) store in a cool dry place away from direct sunlight
📄 Package Label / Principal Display Panel ▾
Principal Display Panel – 74 mL Bottle Label Walgreens Compare to the active ingredient in Biofreeze ® Roll-On †† WALGREENS PHARMACIST RECOMMENDED Cold Therapy Pain Relief MENTHOL 4% / TOPICAL ANALGESIC Roll On Cooling Pain Relief For the temporary relief of arthritis, back pain, sore muscles & joints Soothing menthol Paraben free
2.5 FL OZ (74 ml) Principal Display Panel – 74 mL Bottle Label
Principal Display Panel – 89 mL Tube Label Walgreens Compare to the active ingredient in Biofreeze ® Gel †† WALGREENS PHARMACIST RECOMMENDED Cold Therapy Pain Relief Gel MENTHOL 4% / TOPICAL ANALGESIC Cooling Pain Relief For the temporary relief of arthritis, back pain, sore muscles & joints Soothing menthol Paraben free 3 FL OZ (89 ml) Principal Display Panel – 89 mL Tube Label
Reported adverse events (FAERS)
Top reported reactions
Age at onset
Reporter sex
Serious outcomes
Where does this data come from?
About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |