Home › NDC Lookup › Ingredients › Methylcellulose › 00904-5675-16
FIBER THERAPY methylcellulose 2 g/19g Powder, For Solution, 454 g — NDC 00904-5675-16 package photo

FIBER THERAPY methylcellulose 2 g/19g Powder, For Solution, 454 g

by Major Pharmaceuticals · 454 g in 1 BOTTLE (0904-5675-16)
NDC 00904-5675-16
🏷️ FDA NDC (as labeled) 0904-5675-16 billing pads the labeler segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

🆔 Identity & classification

FDA NDC (as labeled) 0904-5675-16
Product NDC 0904-5675
11-digit billing NDC 00904567516
NCPDP billing unit GM — per gram (weight)
RxCUI 1868843
UNII MRJ667KA5E
Application # M007
SPL Set ID 5dddab8d-0041-4486-9ed9-1dbd13575b47
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2008-04-18
Route ORAL
Dosage form POWDER, FOR SOLUTION
Substance METHYLCELLULOSE (4000 MPA.S)
GPI-14 46300010002900
GPI class Soluble Fiber Therapy
GCN Seq No 068137
GCN 30848
HICL code 034504
Ingredient (HICL) Methylcellulose (With Sugar)
HIC1 code D
Therapeutic class — broad (HIC1) Biliary System/Gastro-Intestinal System
HIC2 code D6
Therapeutic class — intermediate (HIC2) Drugs Acting Principally On The Colon
HIC3 code D6S
Therapeutic class — specific (HIC3) Laxatives And Cathartics
AHFS code 56:12.00.00
AHFS class Cathartics And Laxatives
FDB label name FIBER THERAPY POWDER
FDB brand name Fiber Therapy
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 0904-5675-16 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00904-5675-16. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Bulk-forming laxatives class.

Drug family (ATC) Bulk-forming laxatives
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerMajor Pharmaceuticals
FDA applicationM007 (OTC MONOGRAPH DRUG)
Labeler code00904
First marketedApr 2008
Product typeHuman Otc Drug
Portfolio630 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name FIBER THERAPY POWDER Ingredient Methylcellulose (With Sugar)
🧪 What is this product?

Fiber Therapy is an over-the-counter powder product that you dissolve in liquid and drink by mouth. It contains methylcellulose, a type of fiber that is commonly used to add bulk to stool and help promote regular bowel movements. This product is marketed under FDA's OTC monograph rules for fiber supplements, meaning it follows established category standards rather than individual FDA approval.

Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color Orange
FlavorOrange
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 2968PHW8QP
    A weak organic acid derived from citrus fruits or made through fermentation. It works as a buffer to control pH, a preservative to extend shelf life, and a flavoring agent in medications.
  • UNII H77VEI93A8
    A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
  • UNII EE90ONI6FF
    Potassium citrate is a salt derived from citric acid and potassium. In medicines, it acts as a buffer to adjust and maintain the pH balance of the product, helping keep it stable and palatable.
  • UNII TLM2976OFR
    Riboflavin is a B vitamin used as a colorant and nutritional additive in medications. It gives products a yellow color and may provide supplemental vitamin B2 value.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
  • UNII 506T60A25R
    Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
  • UNII C151H8M554
    A natural sugar derived from sugar cane or sugar beets. It's used as a sweetener, filler, and binder to improve taste, add bulk, and help hold tablet or capsule ingredients together.
  • UNII 7SEV7J4R1U
    A powder made from a naturally occurring mineral. In medicines, talc works as a glidant and anti-caking agent, helping tablets and capsules flow smoothly during manufacturing and preventing clumping.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescitric acid, FD&C yellow 6 aluminum lake, maltodextrin, flavor (natural and artificial), potassium citrate,, silica, sucrose,

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly $0.014 $6.13 / 454 g
Medicaid paysCMS SDUD · 12 mo $0.0240 $10.90 / 454 g
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per g) — tap or hover for the price & month
Jul 2022 Feb 2026 May 2026 Sep 2026 $0.014 $0.013
▲ Up 5% over the last 11 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Fiber Therapy 2 g/19gthis 00904-5675-16 Major 454 g $0.013 — Availability likely —
Citrucel 2 g/19g 00135-0089-69 Haleon 454 g — — Discontinued —
Citrucel 2 g/10.2g 00135-0090-70 Haleon 479 g — — FDA listed —
HEB Fiber Therapy 2 g/10.2g 37808-0716-16 HEB 479 g — — FDA listed —
DRx Choice Fiber Therapy 2 g/10.2g 68163-0517-16 RARITAN 479 g — — FDA listed —
Fiber Therapy 2 g/19g 68788-7995-04 Preferred 454 g — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2008
On the market since
Apr 2008
📍
2026
Currently FDA-listed
18 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🗺️ Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 00904-5675-16, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
3.3K
Units reimbursed last 4 qtrs
1.6M
Gross reimbursed last 4 qtrs
$38K
Avg / prescription
$11.48
Avg / unit
$0.0240
Latest quarter Q1 2026
712Rx
Medicaid pays / g
$0.0240
gross reimbursed
vs
NADAC / g
$0.0135
acquisition cost
=
Spread
+$0.0105
+78% vs cost
What Medicaid paid per g (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
51% FFS 49% MCO
Fee-for-service · 1,680 Rx Managed care · 1,627 Rx
State Medicaid map
Alaska: no data reported AK Maine: 24,516 units · 1,757 per 100k residents ME Washington: no data reported WA Idaho: no data reported ID Montana: 15,890 units · 1,404 per 100k residents MT North Dakota: no data reported ND Minnesota: 718,980 units · 12,532 per 100k residents MN Wisconsin: no data reported WI Michigan: 27,890 units · 278 per 100k residents MI New York: no data reported NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: 37,682 units · 890 per 100k residents OR Nevada: no data reported NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: 174,377 units · 1,390 per 100k residents IL Indiana: 64,922 units · 946 per 100k residents IN Ohio: no data reported OH Pennsylvania: 236,774 units · 1,827 per 100k residents PA New Jersey: 79,416 units · 855 per 100k residents NJ Massachusetts: 138,349 units · 1,976 per 100k residents MA California: no data reported CA Utah: no data reported UT Colorado: no data reported CO Nebraska: 165 units · 8.3 per 100k residents NE Missouri: no data reported MO Kentucky: 40,860 units · 903 per 100k residents KY West Virginia: no data reported WV Virginia: 24,516 units · 281 per 100k residents VA Maryland: no data reported MD Connecticut: no data reported CT Rhode Island: no data reported RI Arizona: no data reported AZ New Mexico: no data reported NM Kansas: no data reported KS Arkansas: no data reported AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: no data reported GA D.C.: no data reported DC Hawaii: no data reported HI Texas: no data reported TX Florida: no data reported FL
Units reimbursed · per 100k residents
8.312,532
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Minnesota 12,532 /100k
2 Massachusetts 1,976 /100k
3 Pennsylvania 1,827 /100k
4 Maine 1,757 /100k
5 Montana 1,404 /100k
6 Illinois 1,390 /100k
7 Indiana 946 /100k
8 Kentucky 903 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Fiber Therapy (this brand).

Top reported reactions

Constipation107
Fall106
Pain95
Hypotension82
Balance Disorder74
Cognitive Disorder73
Dyspnoea72

Age at onset

Child3
Adolescent4
Adult51
Elderly100

Reporter sex

844 reports
Male · 41%
Female · 59%

Serious outcomes

Hospitalization396
Life-threatening95
Death76
Disabling25
Reports over time (by year) — tap or hover for the count & year
2023 2024 2025 2026 110 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
00904-5675-16 You're viewing this 454 g in 1 BOTTLE (0904-5675-16) 2008-04-18 Active

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🚨 Boxed Warning 15 words ▾

TAMPER EVIDENT PACKAGE Do not use if printed seal under cap is torn or missing.

🎯 Indications and Usage 25 words ▾

Uses relieves constipation (irregularity) helps to restore and maintain regularity for treating bowel disorders when recommended by a doctor generally provide effect in 12-72 hours

⏱️ Dosage and Administration 128 words ▾

Directions MIX THIS PRODUCT (CHILD OR ADULT DOSE) WITH AT LEAST 8 OUNCES (A FULL GLASS) OF WATER OR OTHER FLUID. TAKING THIS PRODUCT WITHOUT ENOUGH LIQUID MAY CAUSE CHOKING. SEE CHOKING WARNING use product at the first sign of constipation or irregularity put one dose in a full glass of cold water stir briskly and drink promptly drinking another glass of water is helpful Age Dose adults & children above 12 years of age and over One rounded tablespoon.

(19 g) in 8 ounces of water fluid up to 3 times daily at the first sign of constipation or irregularity children 6 - 12 years of age Children under 6 years of age half the adult dose in 8 ounces of water once daily. ask a doctor

⚠️ Warnings 171 words ▾

Warnings CHOKING: taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking. Do not take this product if you have difficulty in swallowing. If you experience chest pain, vomiting, or difficulty in swallowing or breathing after taking this product, seek immediate medical attention.

Ask a doctor before use if you have abdominal pain, nausea or vomiting a sudden change in bowel habits that persists over a period of 2 weeks sensitivity to any of the ingredients Stop use and ask a doctor if you have rectal bleeding you fail to have a bowl movement after use. These could be signs of a serious condition. Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222. When using this product do not exceed recommended maximum daily dose unless directed by a doctor do not use laxative products for a period longer than one week unless directed by a doctor

🧪 Active Ingredient 14 words ▾

Active ingredient (in each 19g adult dose/ rounded tablespoon) Methylcellulose 2g (a non-allergenic fiber)

🧪 Inactive Ingredients 19 words ▾

Inactive ingredients citric acid, FD&C yellow 6 aluminum lake, maltodextrin, flavor (natural and artificial), potassium citrate, , silica, sucrose,

🎯 Purpose 4 words ▾

Purpose Bulk-forming fiber laxative

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.