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Banophen Diphenhydramine HCl 25 mg Tablet, Film Coated — NDC 00904-5551-24 package photo

Banophen Diphenhydramine HCl 25 mg Tablet, Film Coated

by Major Pharmaceuticals · 2 BLISTER PACK in 1 CARTON (0904-5551-24) / 12 TABLET, FILM COATED in 1 BLISTER PACK
NDC 00904-5551-24
🏷️ FDA NDC (as labeled) 0904-5551-24 billing pads the labeler segment with a zero
This package
Contains12 tablet, film coated in 1 blister pack Cost per ea$0.0370 NADAC Per package$0.89 / 24 tablets Pack sizes2 compare ↓
Also priced by: Medicaid pays $0.5227/unit — full pricing hub ↓
Also comes in: 100 tablets 00904-5551-59
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 0904-5551-24
Product NDC 0904-5551
11-digit billing NDC 00904555124
NCPDP billing unit EA — each (per item)
RxCUI 1049630, 1092421
UNII TC2D6JAD40
UPC 0309045551240
Application # M012
SPL Set ID 69b7f7ca-7a3a-4fe6-a9bb-90b0e6ad62c1
Established class (EPC) Histamine-1 Receptor Antagonist
Mechanism of action Histamine H1 Receptor Antagonists
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 1990-03-02
Route ORAL
Dosage form TABLET, FILM COATED
Substance DIPHENHYDRAMINE HYDROCHLORIDE
GPI-14 41200030100305
GPI class Banophen
GCN Seq No 011594
GCN 46071
HICL code 004480
Ingredient (HICL) Diphenhydramine Hcl
HIC1 code Z
Therapeutic class — broad (HIC1) Body As A Whole
HIC2 code Z2
Therapeutic class — intermediate (HIC2) Antihistamines, Antiserotonins, Immunosuppressants
HIC3 code Z2P
Therapeutic class — specific (HIC3) Antihistamines - 1St Generation
AHFS code 04:04.00.00
AHFS class First Generation Antihistamines
FDB label name BANOPHEN 25 MG TABLET
FDB brand name Banophen
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 0904-5551-24 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00904-5551-24. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Histamine-1 Receptor Antagonist class.

Pharmacologic class Histamine-1 Receptor Antagonist
Drug family (ATC) Propionic acid derivatives, Antihistamines for topical use, Aminoalkyl ethers
How it works Histamine H1 Receptor Antagonists
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerMajor Pharmaceuticals
FDA applicationM012 (OTC MONOGRAPH DRUG)
Labeler code00904
First marketedMar 1990
Product typeHuman Otc Drug
Portfolio630 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name BANOPHEN 25 MG TABLET Ingredient Diphenhydramine Hcl
📖 What it is MedlinePlus · NLM

Diphenhydramine is used to treat allergy and cold symptoms: sneezing runny nose red, itchy, watery eyes itching of the nose or throat Diphenhydramine is also used to treat insomnia (difficulty falling asleep or staying asleep) in adults, but should not be used to make a child sleepy. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Diphenhydramine is also available in combination with other medications. This monograph only includes information about the use of diphenh...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Diphenhydramine is mainly used to temporarily ease the stuffy, sneezy, itchy symptoms of allergies — like hay fever — and the common cold. Think runny nose, sneezing, watery or itc...
  • What exactly does diphenhydramine treat?
  • Yes, and that's one of the most important things to know about this medicine. Drowsiness is one of its most common effects — it crosses into the brain and that's what causes the se...
  • It depends on your child's age and the product. Most oral diphenhydramine products are not recommended for children under 6, and liquid products labeled for children are generally...
📖 Read our full Diphenhydramine guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color pink
ShapeOval
Imprint44;329
Size11 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII ZK64F7XSTX
    A red synthetic colorant made by combining D&C Red No. 27 dye with aluminum salts. It's used to give tablets, capsules, or other medicines their red or pink color.
  • UNII O7TSZ97GEP
    A mineral compound that serves as a filler and binding agent in tablets and capsules. It adds bulk to the medicine and helps hold ingredients together during manufacturing.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII OP1R32D61U
    Microcrystalline cellulose is a purified form of cellulose, a natural fiber from plant sources. It acts as a binder and filler in tablets and capsules, helping hold ingredients together and give the medicine its shape and size.
  • UNII 3WJQ0SDW1A
    Polyethylene glycol is a synthetic liquid or solid polymer used in medicines as a solvent, lubricant, and humectant. It helps dissolve active ingredients, reduces friction during manufacturing, and retains moisture in the final product.
  • UNII 532B59J990
    Polyvinyl alcohol is a synthetic polymer made from plant-derived materials. It's used as a binder to hold ingredients together, a film-former in coatings, and a thickener in liquid formulations.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
  • UNII O8232NY3SJ
    A plant-based carbohydrate derived from corn kernels. It acts as a filler to add bulk, a binder to hold ingredients together, and a disintegrant to help the tablet break apart in your stomach for absorption.
  • UNII 4ELV7Z65AP
    Stearic acid is a fatty acid derived from plant or animal sources. It acts as a binder and lubricant in tablets and capsules, helping them hold together and flow smoothly during manufacturing.
  • UNII 7SEV7J4R1U
    A powder made from a naturally occurring mineral. In medicines, talc works as a glidant and anti-caking agent, helping tablets and capsules flow smoothly during manufacturing and preventing clumping.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.

11 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescorn starch, D&C red #27 aluminum lake, dibasic calcium phosphate dihydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, silicon dioxide, stearic acid, talc, titanium dioxide

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.037 $0.89 / 24 tablets
Medicaid paysCMS SDUD · 12 mo $0.5227 $12.54 / 24 tablets
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Jan 2022 Aug 2022 Jan 2026 Sep 2026 $0.040 $0.032
▲ Up 8% over the last 24 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
good sense allergy relief 25 mg 00113-0479-62 L. 24 tablets $0.037 — Availability likely —
Diphenhydramine HCl 25 mg 00536-1214-29 Rugby 100 tablets $0.037 — Availability likely —
Banophen 25 mgthis 00904-5551-24 Major 12 tablets $0.037 — Availability likely —
Allergy Relief 25 mg 46122-0441-62 Amerisource 12 tablets $0.037 — Availability likely —
Allergy Relief 25 mg 49483-0061-01 TIME 100 tablets $0.037 — Availability likely —
Diphenhydramine Hydrochloride 25 mg 68094-0018-61 Precision 100 tablets $0.037 — Availability likely —
Allergy Relief 25 mg 70000-0136-01 Cardinal 12 tablets $0.037 — Availability likely —
Allergy Relief 25 mg 70677-1014-01 Strategic 12 tablets $0.037 — Availability likely —
Allergy Relief 25 mg 70677-1238-01 Strategic 120 tablets $0.037 — Availability likely —
Allergy Relief 25 mg 83324-0088-01 CHAIN 100 tablets $0.037 — Availability likely —
good sense nighttime sleep aid 25 mg 00113-0431-62 L. 2 tablets $0.060 — Availability likely +62%
Sleep Tabs 25 mg 00904-4274-51 Major 50 tablets $0.060 — Availability likely +62%
Sleep Aid 25 mg 46122-0651-62 Amerisource 12 tablets $0.060 — Availability likely +62%
Nighttime Sleep Aid 25 mg 70677-1128-01 Strategic 12 tablets $0.060 — Availability likely +62%
Nighttime Sleep Aid 25 mg 83324-0110-32 CHAIN 32 tablets $0.060 — Availability likely +62%
Rest Simply 25 mg 83324-0113-01 CHAIN 100 tablets $0.060 — Availability likely +62%
Nighttime Sleep Aid 25 mg 63868-0611-32 Chain 32 tablets $0.066 — FDA listed +77%
Sleep Aid 25 mg 70000-0244-01 Cardinal 12 tablets $0.066 — FDA listed +77%
Allergy Relief 25 mg 00363-0100-61 WALGREENS 600 tablets — — FDA listed —
Sleep II Nighttime Sleep Aid 25 mg 00363-0189-46 Walgreen 96 tablets — — FDA listed —
Sleep Aid Nighttime 25 mg 00363-0367-08 Walgreen 12 tablets — — FDA listed —
Allergy Relief 25 mg 00363-3291-08 Walgreen 12 tablets — — FDA listed —
Allergy Relief 25 mg 00363-6141-12 Walgreen 100 tablets — — FDA listed —
Sleep Aid 25 mg 00363-6720-12 Walgreen 100 tablets — — FDA listed —
Allergy Relief 25 mg 00363-9023-36 Walgreens 365 tablets — — FDA listed —
Allergy Relief 25 mg 00363-9024-60 Walgreens 600 tablets — — FDA listed —
PhysiciansCare Allergy Antihistamine 25 mg 00924-0056-01 Acme 1 tablet — — FDA listed —
Allergy Relief 25 mg 11673-0494-01 TARGET 100 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 11673-0496-01 TARGET 100 tablets — — FDA listed —
Allergy Relief 25 mg 11822-0329-01 Rite 365 tablets — — FDA listed —
sleep aid 25 mg 11822-0672-06 Rite 200 tablets — — FDA listed —
Sleep Aid 25 mg 11822-3670-02 Rite 100 tablets — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 17714-0135-01 Advance 100 tablets — — FDA listed —
Allergy Relief 25 mg 21130-0329-06 Better 200 tablets — — Discontinued —
Allergy Relief 25 mg 21130-0596-01 BETTER 100 tablets — — FDA listed —
Sleep Aid Nighttime 25 mg 21130-0763-06 Better 200 tablets — — FDA listed —
Good Neighbor Pharmacy allergy 25 mg 24385-0479-62 Amerisource 24 tablets — — Discontinued —
Allergy Relief 25 mg 29485-9285-02 Lil' 2 tablets — — FDA listed —
topcare sleep aid nighttime 25 mg 36800-0431-62 Topco 2 tablets — — FDA listed —
Sleep Aid 25 mg 36800-0672-06 Topco 200 tablets — — FDA listed —
Allergy Relief 25 mg 36800-0909-01 TopCo 12 tablets — — FDA listed —
Allergy Relief Caplet 25 mg 36800-0937-40 TOPCO 400 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 37808-0019-02 HEB 32 tablets — — FDA listed —
nighttime sleep aid 25 mg 37808-0431-62 H 2 tablets — — FDA listed —
Allergy Relief 25 mg 37808-0590-02 HEB 12 tablets — — FDA listed —
Allergy Relief 25 mg 37808-0932-08 H 12 tablets — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 37835-0641-01 Bi-Mart 100 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 37835-0812-36 Bi-Mart 36 tablets — — FDA listed —
Allergy Relief 25 mg 41163-0290-03 United 100 tablets — — FDA listed —
Allergy Relief 25 mg 41163-0329-08 United 12 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 41163-0367-06 United 200 tablets — — FDA listed —
Allergy 25 mg 41226-0160-01 Kroger 100 tablets — — FDA listed —
allergy 25 mg 41250-0479-53 Meijer 12 tablets — — Discontinued —
allergy relief 25 mg 41250-0614-12 Meijer 100 tablets — — FDA listed —
Allergy Relief 25 mg 41520-0290-11 FOODHOLD 300 tablets — — FDA listed —
careone nighttime sleep aid 25 mg 41520-0431-62 American 2 tablets — — FDA listed —
careone allergy relief 25 mg 41520-0778-62 American 24 tablets — — Discontinued —
Allergy Relief 25 mg 42507-0290-01 HYVEE 12 tablets — — FDA listed —
Rest Simply 25 mg 42507-0291-03 HYVEE 100 tablets — — FDA listed —
Medique at Home Diphen 25 mg 47682-0166-50 Unifirst 1 tablet — — FDA listed —
Medique Diphen 25 mg 47682-0167-46 Unifirst 1 tablet — — FDA listed —
Allergy Relief 25 mg 49035-0164-12 Wal-Mart 100 tablets — — Discontinued —
Sleep Aid Nighttime 25 mg 49035-0367-08 Wal-Mart 12 tablets — — FDA listed —
Sleep Aid NightTime 25 mg 49035-0672-51 Wal-Mart 365 tablets — — FDA listed —
Allergy Relief 25 mg 49035-0929-12 Wal-Mart 100 tablets — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 49483-0329-00 Time-Cap 100000 tablets — — FDA listed —
Banophen 25 mg 50090-5546-00 A-S 12 tablets — — FDA listed —
Benadryl Ultra Tab 25 mg 50269-0226-54 JC 25 tablets — — FDA listed —
Benadryl Allergy 25 mg 50269-0528-00 JC 20 tablets — — FDA listed —
Histaprin 25 mg 50332-0150-04 NorMed 50 tablets — — FDA listed —
Benadryl 25 mg 50580-0226-50 Kenvue 100 tablets — — FDA listed —
Benadryl 50580-0370-01 Kenvue 100 tablets — — FDA listed —
Simply Sleep 25 mg 50580-0843-12 Kenvue 100 tablets — — FDA listed —
Allergy Relief 25 mg 50804-0048-93 Good 24 tablets — — FDA listed —
Allergy Relief 25 mg 50844-0229-08 L.N.K. 12 tablets — — FDA listed —
Allergy Relief 25 mg 50844-0329-02 L.N.K. 12 tablets — — FDA listed —
CVS Diphenhydramine Hydrochloride 25 mg 51316-0186-25 CVS 365 tablets — — FDA listed —
CVS Diphenhydramine Hydrochloride 25 mg 51316-0191-00 CVS 365 tablets — — FDA listed —
Sleep Aid Nighttime 25 mg 51316-0367-12 CVS 100 tablets — — FDA listed —
diphenhydramine hydrochloride 25 mg 51662-1674-01 HF 1 tablet — — FDA listed —
CAREALL Diphenhydramine 25 mg 51824-0056-01 New 100 tablets — — FDA listed —
CAREALL Allergy Relief 25 mg 51824-0102-01 New 100 tablets — — FDA listed —
Benadryl 25 mg 53209-3001-02 Morning 2 tablets — — FDA listed —
Allergy Relief 25 mg 53942-0190-05 Demoulas 400 tablets — — FDA listed —
Allergy 25 mg 53943-0090-01 Discount 12 tablets — — FDA listed —
Nyt Time Sleep Caps 25 mg 53943-0128-03 DISCOUNT 72 tablets — — FDA listed —
Rest Simply 25 mg 53943-0191-01 DISCOUNT 6 tablets — — FDA listed —
Sleep-Aid 25 mg 55301-0189-23 ARMY 72 tablets — — FDA listed —
Allergy Relief 25 mg 55301-0329-12 ARMY 100 tablets — — FDA listed —
Allergy Relief 25 mg 55319-0329-02 Family 12 tablets — — FDA listed —
Sleep Aid Nighttime 25 mg 55319-0367-08 Family 12 tablets — — FDA listed —
Allergy Relief 25 mg 55681-0323-03 TWIN 300 tablets — — FDA listed —
Allergy Relief 25 mg 55910-0293-08 DOLGENCORP, 12 tablets — — FDA listed —
Allergy Relief 25 mg 55910-0329-51 DOLGENCORP, 365 tablets — — FDA listed —
dg health sleep aid 25 mg 55910-0431-62 Dolgencorp 2 tablets — — FDA listed —
DG Health Allergy 25 mg 55910-0479-78 Dolgencorp 100 tablets — — Discontinued —
Sleep Aid 25 mg 55910-0614-12 DOLGENCORP, 100 tablets — — FDA listed —
Sleep Aid Night Time 25 mg 55910-0687-08 DOLGENCORP, 12 tablets — — FDA listed —
Sleep Aid Night Time 25 mg 55910-0772-51 DOLGENCORP, 365 tablets — — FDA listed —
Allergy Relief 25 mg 55910-0959-24 DOLGENCORP, 24 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 56062-0091-01 PUBLIX 6 tablets — — FDA listed —
allergy 25 mg 56062-0479-62 Publix 24 tablets — — Discontinued —
Allergy 25 mg 56062-0923-08 Publix 12 tablets — — FDA listed —
Sleep 25 mg 57243-0189-21 Salado 16 tablets — — FDA listed —
Diphenhydramine 25 mg 57344-0090-02 AAA 12 tablets — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 57344-0091-03 AAA 100 tablets — — FDA listed —
Geri-Dryl allergy relief 25 mg 57896-0683-01 Geri-Care 100 tablets — — FDA listed —
Nighttime Sleep-aid 25 mg 57896-0785-72 Geri-Care 72 tablets — — FDA listed —
Kroger Nighttime Sleep Aid CAPLET 25 mg 59450-0601-01 The 100 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 59779-0367-08 CVS 12 tablets — — Discontinued —
Allergy Relief Dye-Free 25 mg 59779-0614-06 CVS 200 tablets — — FDA listed —
Allergy Relief 25 mg 59779-0923-03 CVS 10 tablets — — FDA listed —
Allergy Relief 25 mg 61504-0090-03 AMERIFOODS 100 tablets — — FDA listed —
Nighttime SleepAid 25 mg 61504-0091-03 AMERIFOODS 100 tablets — — FDA listed —
Nytol 25 mg 63029-0211-01 Medtech 32 tablets — — FDA listed —
Sominex 25 mg 63029-0554-01 Medtech 8 tablets — — FDA listed —
Allergy Relief 25 mg 63868-0492-10 Chain 100 tablets — — FDA listed —
Rest Simply 25 mg 63868-0772-10 Chain 100 tablets — — FDA listed —
Allergy Relief 25 mg 63941-0090-01 VALU 12 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 63941-0091-01 VALU 6 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 63941-0219-01 VALU 16 tablets — — FDA listed —
Allergy Medicine 25 mg 63981-0329-78 COSTCO 600 tablets — — FDA listed —
welby allergy relief 25 mg 64024-0479-78 Aldi 100 tablets — — FDA listed —
Allergy, Circle K 25 mg 66715-5154-08 Lil' 12 tablets — — FDA listed —
Sleep-Aid, Circle K 25 mg 66715-5503-08 Lil' 12 tablets — — FDA listed —
Circle K Allergy Antihistamine 25 mg 66715-5554-02 Lil' 2 tablets — — Discontinued —
Allergy 36ct, Caseys 4good 25 mg 66715-6314-08 Lil' 12 tablets — — FDA listed —
Benadryl 25 mg 66715-6406-02 Lil' 2 tablets — — FDA listed —
Benadryl 25 mg 66715-6506-02 Lil' 2 tablets — — FDA listed —
Allergy Relief, 24-7 Lift by 7-Eleven 25 mg 66715-6514-08 Lil' 12 tablets — — FDA listed —
Sleep-Aid, Lil Drug Store 25 mg 66715-6643-08 Lil' 12 tablets — — FDA listed —
Allergy, Lil Drug Store 25 mg 66715-6914-08 Lil' 12 tablets — — FDA listed —
Allergy Relief, 24-7 Life by 7-Eleven 25 mg 66715-8157-03 Lil' 6 tablets — — FDA listed —
Benadryl 25 mg 66715-9706-02 Lil' 2 tablets — — FDA listed —
Allergy 25 mg 66715-9711-07 Lil' 100 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 67091-0115-10 WinCo 100 tablets — — FDA listed —
Allergy Relief Complete 25 mg 67091-0200-10 WinCo 100 tablets — — FDA listed —
Sleep Aid 25 mg 67091-0339-24 WinCo 12 tablets — — FDA listed —
Benadryl Allergy Ultratab 25 mg 67414-0226-00 Jones 2 tablets — — FDA listed —
Benadryl Ultratabs 25 mg 67751-0166-01 Navajo 2 tablets — — FDA listed —
Sominex 25 mg 67751-0221-01 Navajo 8 tablets — — FDA listed —
Allergy Relief 25 mg 68196-0160-60 SAM'S 600 tablets — — FDA listed —
Aller-Ben 25 mg 68196-0829-78 Sam's 600 tablets — — Discontinued —
Allergy Relief 25 mg 68391-0160-33 BJWC 600 tablets — — FDA listed —
Berkley and Jensen Allergy Relief 25 mg 68391-0200-79 BJWC 400 tablets — — FDA listed —
Geri-Dryl allergy relief 25 mg 68788-8104-00 Preferred 10 tablets — — FDA listed —
Allergy Relief 25 mg 68998-0090-03 Marc 100 tablets — — FDA listed —
Rest Simply 25 mg 68998-0091-01 Marc 12 tablets — — FDA listed —
Diphenhydramine HCl 25mg 25 mg 69168-0002-93 Allegiant 24 tablets — — FDA listed —
Allergy 25 mg 69168-0048-01 Allegiant 100 tablets — — FDA listed —
Sleep Tabs For Nighttime use 25 mg 69168-0247-24 Allegiant 24 tablets — — FDA listed —
Sleep Aid 25 mg 69168-0263-30 Allegiant 30 tablets — — FDA listed —
Allergy Relief 25 mg 69452-0444-31 BIONPHARMA 600 tablets — — FDA listed —
Allergy Relief 25 mg 69517-0003-01 HealthLife 100 tablets — — Discontinued —
Nighttime Sleep Aid 25 mg 69517-0004-03 HealthLife 300 tablets — — Discontinued —
Diphenhydramine HCL 25 mg 69618-0025-01 Reliable 100 tablets — — FDA listed —
Sleep-Aid Nighttime 25 mg 69842-0672-51 CVS 365 tablets — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 69842-0834-51 CVS 365 tablets — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 69842-0981-08 CVS 200 tablets — — FDA listed —
Benadryl Allergy 25 mg 70264-0024-01 R 2 tablets — — FDA listed —
GOOD REMEDIES Nighttime Sleep Aid Caplets 25 mg 70692-0011-06 Strive 60 tablets — — FDA listed —
GOOD REMEDIES Allergy Relief 25 mg 70692-0022-06 Strive 60 tablets — — FDA listed —
Diphenhydramine Hydrochloride 25mg 25 mg 70692-0148-01 Strive 100 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 70692-0151-46 Strive 72 tablets — — FDA listed —
Allergy Relief 25 mg 71141-0177-32 Lidl 100 tablets — — FDA listed —
Benadryl 25 mg 71205-0521-06 Proficient 2 tablets — — FDA listed —
Banophen 25 mg 71205-0611-20 Proficient 20 tablets — — FDA listed —
Allergy Relief 25 mg 71679-0106-06 Health 600 tablets — — FDA listed —
Nighttime Sleep Aid 25 mg 71679-0110-06 Health 600 tablets — — FDA listed —
Somnitabs 25 mg 72036-0019-02 HARRIS 32 tablets — — FDA listed —
Allergy Relief 25 mg 72036-0090-01 Harris 12 tablets — — FDA listed —
Rest Simply 25 mg 72036-0091-01 Harris 12 tablets — — FDA listed —
Sleep Aid 25 mg 72090-0020-10 Pioneer 100 tablets — — FDA listed —
Allergy Relief 25 mg 72090-0021-60 Pioneer 600 tablets — — FDA listed —
Allergy Relief 25 mg 72090-0029-60 Pioneer 600 tablets — — FDA listed —
Allergy Relief 25 mg 72090-0040-01 Pioneer 1000 tablets — — FDA listed —
basic care allergy relief 25 mg 72288-0479-78 Amazon.com 100 tablets — — FDA listed —
Benadryl Allergy Ultratab 25 mg 73097-0004-02 Savings 2 tablets — — FDA listed —
Diphenhydramine HCl 25 mg/25mg 73376-0003-80 INVAHEALTH 1000 mg — — FDA listed —
Sleep Aid 25 mg 76168-0015-07 Velocity 36 tablets — — FDA listed —
Allergy 25 mg 76168-0121-12 Velocity 100 tablets — — FDA listed —
diphenhydramine hydrochloride 25 mg 76457-0002-00 Simpex 100 tablets — — FDA listed —
meijer Allergy Relief 25 mg 79481-0148-04 Meijer, 24 tablets — — FDA listed —
meijer NIGHTTIME Sleep Aid CAPLET 25 mg 79481-0151-01 Meijer, 100 tablets — — FDA listed —
Allergy Relief 25 mg 79903-0056-10 Wal-Mart 100 tablets — — FDA listed —
equate nighttime sleep aid 25 mg 79903-0274-36 WALMART 365 tablets — — FDA listed —
equate allergy relief 25 mg 79903-0297-10 WALMART 100 tablets — — FDA listed —
Allergy Relief 25 mg 79903-0491-10 Walmart 100 tablets — — FDA listed —
Nighttime Sleep-aid 25 mg 80136-0785-96 NORTHEAST 96 tablets — — FDA listed —
Betr sleep aid 25 mg 80267-0431-67 Live 2 tablets — — FDA listed —
Night Time Sleep-Aid 25 mg 80513-0383-22 Advanced 220 tablets — — FDA listed —
Allergy Relief 25 mg 80513-0722-06 Advanced 600 tablets — — FDA listed —
Allergy Relief 25 mg 81522-0109-03 FSA 100 tablets — — FDA listed —
AXIV Allergy Relief 25 mg 82706-0021-02 VIVUNT 100 tablets — — FDA listed —
Allergy Relief 25 mg 82725-1001-01 Cabinet 600 tablets — — FDA listed —
ValuMeds Allergy Relief Antihistamine Diphenhydramine HCl 25 mg 82725-1101-01 Cabinet 600 tablets — — FDA listed —
Cabinet Allergy Relief Refill Diphenhydramine HCI 25 mg 82725-3001-02 Cabinet 120 tablets — — FDA listed —
Goodmeds Allergy Relief Diphenhydramine HCl 25 mg 82725-4001-01 Cabinet 600 tablets — — FDA listed —
Goodmeds Allergy Relief Diphenhydramine HCl 25 mg 82725-4101-01 Cabinet 600 tablets — — FDA listed —
Goodmeds Allergy Relief 25 mg 82725-4201-01 Cabinet 600 tablets — — FDA listed —
Allergy Relief 25 mg 83059-0021-03 Shield 36 tablets — — FDA listed —
Banophen 25 mg 83112-0555-59 Health 1 tablet — — FDA listed —
Dormmy-Lon 25 mg 83164-0000-01 Haendel 60 tablets — — FDA listed —
Geri-Dryl allergy relief 25 mg 83939-0683-01 VerityRx 1 tablet — — FDA listed —
Allergy Relief 25 mg 84324-0004-01 NUVICARE 300 tablets — — FDA listed —
Sleep Aid 25 mg 84324-0016-01 NUVICARE 200 tablets — — FDA listed —
Geri-Dryl allergy relief 25 mg 85766-0092-01 Sportpharm 100 tablets — — FDA listed —
Dr. Simi Allergy Relief 25 mg 85786-0202-24 Farmacias 24 tablets — — FDA listed —
Allergy Relief 25 mg 85828-0048-32 Grocery 100 tablets — — FDA listed —
Allergy Relief 25 mg 87509-0001-06 Famora 650 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
1990
On the market since
Mar 1990
📍
2026
Currently FDA-listed
36 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🗺️ Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 00904-5551-24, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
8.3K
Units reimbursed last 4 qtrs
276.4K
Gross reimbursed last 4 qtrs
$144.5K
Avg / prescription
$17.40
Avg / unit
$0.5227
Latest quarter Q1 2026
2.4KRx
Medicaid pays / ea
$0.5227
gross reimbursed
vs
NADAC / ea
$0.0370
acquisition cost
=
Spread
+$0.4857
+1313% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
51% FFS 49% MCO
Fee-for-service · 4,214 Rx Managed care · 4,092 Rx
State Medicaid map
Alaska: no data reported AK Maine: 377 units · 27.0 per 100k residents ME Washington: 4,863 units · 62.3 per 100k residents WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: 16,762 units · 292 per 100k residents MN Wisconsin: no data reported WI Michigan: 16,822 units · 168 per 100k residents MI New York: 33,473 units · 171 per 100k residents NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: 558 units · 13.2 per 100k residents OR Nevada: 3,704 units · 116 per 100k residents NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: 5,302 units · 42.3 per 100k residents IL Indiana: 4,702 units · 68.5 per 100k residents IN Ohio: 25,754 units · 219 per 100k residents OH Pennsylvania: 13,695 units · 106 per 100k residents PA New Jersey: 10,596 units · 114 per 100k residents NJ Massachusetts: 15,190 units · 217 per 100k residents MA California: 81,419 units · 209 per 100k residents CA Utah: no data reported UT Colorado: no data reported CO Nebraska: no data reported NE Missouri: no data reported MO Kentucky: 7,512 units · 166 per 100k residents KY West Virginia: no data reported WV Virginia: 3,482 units · 39.9 per 100k residents VA Maryland: 3,728 units · 60.3 per 100k residents MD Connecticut: no data reported CT Rhode Island: no data reported RI Arizona: 2,684 units · 36.1 per 100k residents AZ New Mexico: no data reported NM Kansas: 582 units · 19.8 per 100k residents KS Arkansas: no data reported AR Tennessee: 3,347 units · 47.0 per 100k residents TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: 349 units · 11.9 per 100k residents MS Alabama: no data reported AL Georgia: 21,547 units · 195 per 100k residents GA D.C.: no data reported DC Hawaii: no data reported HI Texas: no data reported TX Florida: no data reported FL
Units reimbursed · per 100k residents
11.9292
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Minnesota 292 /100k
2 Ohio 219 /100k
3 Massachusetts 217 /100k
4 California 209 /100k
5 Georgia 195 /100k
6 New York 171 /100k
7 Michigan 168 /100k
8 Kentucky 166 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

💊 Medicaid utilization by pack size

Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
100 tablets00904-5551-59 92,775 Rx · $786,059
12 tablets this page00904-5551-24 8,306 Rx · $144,488
Drug total (last 4 qtrs): 101,081 Rx · 4,011,941 units · $930,547 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.

📊 Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Diphenhydramine HCl (matched by generic name) — the program that covers self-administered drugs. 8 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Diphenhydramine HCl. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$374.3K
Claims incl. refills
20.3K
Beneficiaries
11.2K
Spend / beneficiary
$33.36
Spend / claim
$18.44
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Banophen (this brand).

Top reported reactions

Completed Suicide760
Death561
Nausea517
Fatigue508
Pain474
Infusion Related Reaction467
Dyspnoea440

Reporter sex

9,045 reports

Serious outcomes

Death2,800
Life-threatening466
Reports over time (by year) — tap or hover for the count & year
2021 2022 2024 2026 357 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startStatus
00904-5551-24 You're viewing this 2 BLISTER PACK in 1 CARTON (0904-5551-24) / 12 TABLET, FILM COATED in 1 BLISTER PACK $0.0370 / ea $0.89 1990-03-02 Active
00904-5551-59 1 BOTTLE, PLASTIC in 1 CARTON (0904-5551-59) / 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC $0.0370 / ea $3.70 1990-03-02 Active

This pack has the lowest per-ea cost of the 2 priced pack sizes ($0.0370 NADAC).

This pack accounts for about 8.2% of this product's recent Medicaid fills; most go to a different pack size. See all packs ↓

Pack size FAQ

What quantity is in NDC 00904-5551-24?
NDC 00904-5551-24 is listed by the FDA — 2 blister pack in 1 carton / 12 tablet, film coated in 1 blister pack.
What NDC number is used to bill for this package of Banophen Diphenhydramine HCl 25 mg Tablet, Film Coated?
Bill NDC 00904-5551-24 — the 11-digit billing format is 00904555124. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 38 words ▾

Uses temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose itchy, watery eyes sneezing itching of the nose or throat temporarily relieves these symptoms due to the common cold: runny nose sneezing

⏱️ Dosage and Administration 55 words ▾

Directions do not take more than directed take every 4 to 6 hours, or as directed by a doctor do not take more than 6 times in 24 hours adults and children 12 years and over 1 to 2 tablets children 6 to under 12 years 1 tablet children under 6 years do not use

⚠️ Warnings 127 words ▾

Warnings Do not use to make a child sleepy with any other product containing diphenhydramine, even one used on skin Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma difficulty in urination due to enlargement of the prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers. When using this product excitability may occur, especially in children marked drowsiness may occur alcohol, sedatives, and tranquilizers may increase drowsiness avoid alcoholic beverages use caution when driving a motor vehicle or operating machinery If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 45 words ▾

Other information each tablet contains: calcium 30 mg TAMPER EVIDENT: DO NOT USE IF OUTER PACKAGE IS OPENED OR BLISTER IS TORN OR BROKEN store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) protect from moisture see end flap for expiration date and lot number

🧪 Active Ingredient 9 words ▾

Active ingredient (in each tablet) Diphenhydramine HCl 25 mg

🧪 Inactive Ingredients 28 words ▾

Inactive ingredients corn starch, D&C red #27 aluminum lake, dibasic calcium phosphate dihydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, silicon dioxide, stearic acid, talc, titanium dioxide

🎯 Purpose 2 words ▾

Purpose Antihistamine

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 00904-5529-52 · Major 00904-5577-20 · Major →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.