Home › NDC Lookup › Ingredients › Avobenzone, Octisalate And Octocrylene › 11559-0052-01
RESILIENCE MULTI-EFFECT TRI-PEPTIDE FACE AND NECK CREME BROAD SPECTRUM SPF 15 AVOBENZONE, OCTISALATE, and OCTOCRYLENE 30 mg/mL; 45 mg/mL; 27 mg/mL Cream — NDC 11559-0052-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

RESILIENCE MULTI-EFFECT TRI-PEPTIDE FACE AND NECK CREME BROAD SPECTRUM SPF 15 AVOBENZONE, OCTISALATE, and OCTOCRYLENE 30 mg/mL; 45 mg/mL; 27 mg/mL Cream — NDC 11559-052-01 (Billing 11559-0052-01)

by ESTEE LAUDER INC · 1 JAR in 1 CARTON / 50 mL in 1 JAR

This is a package of RESILIENCE MULTI-EFFECT TRI-PEPTIDE FACE AND NECK CREME BROAD SPECTRUM SPF 15 AVOBENZONE, OCTISALATE, and OCTOCRYLENE 30 mg/mL; 45 mg/mL; 27 mg/mL Cream from ESTEE LAUDER INC, no longer marketed (first marketed Nov 2018), no longer in the FDA NDC Directory. It is the main listing for this product, which comes in 6 package sizes.

NDC 11559-0052-01
🏷️ FDA NDC (as labeled) 11559-052-01 billing pads the product segment with a zero
This package
Contains50 mL in 1 jar Pack sizes6 compare ↓
Main listing for product 11559-052 · Also comes in: 75 mL 11559-052-02 30 mL 11559-052-03 15 mL 11559-052-04 7 ml 11559-052-05 7 ml 11559-052-06
OTC Discontinued Non-controlled ⚠ Inactivated by FDA ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 11559-052-01 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
11559 labeler · 052 product · 01 package
Package marketed since
Nov 1, 2018
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 1155905201 4
FDA record last changed
Jul 24, 2026
⚠️
Excluded from the active FDA NDC Directory. FDA inactivated this product’s listing record, so it is excluded from the active NDC Directory. The listing was last certified through Dec 2026. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 11559-052-01
Product NDC 11559-052
11-digit billing NDC 11559005201
UNII G63QQF2NOX, 4X49Y0596W, 5A68WGF6WM
Application # M020
SPL Set ID 1c6b62cd-ebe3-4043-b256-0f3e0614b390
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Inactivated by FDA (certified through Dec 2026)
Marketing start 2018-11-01
Route TOPICAL
Dosage form CREAM
Substance AVOBENZONE; OCTISALATE; OCTOCRYLENE
Why two NDCs? The FDA registers this code as 11559-052-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 11559-0052-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

This is a topical cream for the face and neck marketed as an over-the-counter monograph sunscreen product. It contains three UV-filtering ingredients, avobenzone, octisalate, and octocrylene, which are commonly used together in sunscreens to absorb ultraviolet radiation and help protect skin from sun exposure. The product is formulated with a broad-spectrum SPF 15 rating. Topical sunscreen creams of this type are typically applied to exposed skin as part of sun protection routines.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 75 mL 30 mL 15 mL 7 ml 7 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
11559-0052-01 You're viewing this Main listing 1 JAR in 1 CARTON / 50 mL in 1 JAR 2018-11-01 — Inactivated by FDA
11559-0052-02 11559-052-02 1 JAR in 1 CARTON / 75 mL in 1 JAR 2022-03-02 — Inactivated by FDA
11559-0052-03 11559-052-03 1 JAR in 1 CARTON / 30 mL in 1 JAR 2022-03-02 — Inactivated by FDA
11559-0052-04 11559-052-04 1 JAR in 1 CARTON / 15 mL in 1 JAR 2022-03-02 — Inactivated by FDA
11559-0052-05 11559-052-05 7 mL in 1 PACKET 2022-03-02 — Discontinued by firm
11559-0052-06 11559-052-06 7 mL in 1 JAR 2023-11-01 — Inactivated by FDA

Pack size FAQ

What quantity is in this package?
This package is listed by the FDA — 1 jar in 1 carton / 50 ml in 1 jar.
What NDC number is used to bill for this package of RESILIENCE MULTI-EFFECT TRI-PEPTIDE FACE AND NECK CREME BROAD SPECTRUM SPF 15 AVOBENZONE, OCTISALATE, and OCTOCRYLENE 30 mg/mL; 45 mg/mL; 27 mg/mL Cream?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Resilience Multi-Effect Tri-Peptide Face And Neck Creme Broad Spectrum Spf 15 30 mg/mL; 45 mg/mL; 27 mg/mLthis 11559-0052-01 ESTEE 1 jar — — Discontinued —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2018
On the market since
Nov 2018
📍
2026
Currently FDA-listed
8 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII L4EL31FWIL
    A synthetic peptide (short chain of amino acids) used as a conditioning or texture-enhancing agent in topical formulations. It helps improve product feel and skin compatibility in creams and lotions.
  • UNII 290O2PQ83R
    A stabilized form of vitamin C used in topical products as an antioxidant ingredient. It helps prevent degradation of other active ingredients and maintains product stability during storage.
  • UNII 5SL0G7R0OK
    A simple sugar made from corn or other plants, used in medicines as a filler and sweetener. It helps create the right texture and taste in tablets, powders, and liquid formulations.
  • UNII SDS87L369F
    A natural oil extracted from avocado fruit. It's used as an emollient and skin-conditioning agent in topical formulations to help soften and smooth the product's texture.
  • UNII 1P9D0Z171K
    BHT is a synthetic antioxidant that prevents fats and oils in medicines from breaking down and becoming rancid. It helps keep the product stable and effective during storage.
  • UNII 3XUS85K0RA
    Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
  • UNII 2EH13UN8D3
    A synthetic compound used as a solvent and penetration enhancer in topical formulations. It helps dissolve active ingredients and allows them to penetrate the skin more effectively.
  • UNII S4827SZE3L
    A mixture of fatty alcohols derived from plant or petroleum sources with 12 to 16 carbon atoms. Used as an emulsifier and thickening agent to help blend water and oil components and give the product its desired texture.
  • UNII 3G6A5W338E
    Caffeine is a natural stimulant compound commonly extracted from coffee beans and tea leaves. In medicines, it serves as an active booster in pain relievers and cold products to enhance alertness and improve the effectiveness of other ingredients.
  • UNII 00YIU5438U
    Caprylyl glycol is a clear liquid derived from coconut oil. In medicines, it acts as a humectant to retain moisture, a preservative booster to prevent microbial growth, and a solvent to help dissolve or mix other ingredients.
  • UNII 936JST6JCN
    Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
  • UNII 97C5T2UQ7J
    Cholesterol is a fatty substance found naturally in animal tissues. In medications, it's used as an ingredient in liposomal formulations and lipid-based drug delivery systems to help encapsulate and stabilize active drugs for better absorption.
  • UNII 6X7K9I5QR7
    A dipeptide compound derived from carnosine, used as an antioxidant and stabilizing agent in formulations to help protect the product and maintain ingredient stability during storage.
  • UNII A1CB3Z898P
    A synthetic oily compound made from plant-derived fatty acids and fumaric acid. It acts as a solubilizer and emulsifier to help dissolve and stabilize active ingredients in the medicine.
  • UNII 92RU3N3Y1O
    Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
  • UNII 9G1OE216XY
    Docosanol is a waxy, fatty alcohol derived from plant sources. It acts as an emollient and thickener in topical medicines, helping to soften the skin and improve product texture and stability.
  • UNII 8NLQ36F6MM
    Edetate disodium anhydrous is a chemical compound that binds to metal ions in a medicine. It's used as a stabilizer to prevent unwanted chemical reactions and help keep the drug product effective during storage.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII X3W0AM1JLX
    A synthetic red dye used to color medicines and products. It helps make pills, liquids, and capsules visually distinct and easier to identify.
  • UNII 0T8392U5N1
    Glucose oxidase is an enzyme derived from fungi that breaks down glucose. It's used in medicines as a preservative and oxygen scavenger to protect other ingredients from degradation and extend shelf life.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 230OU9XXE4
    A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
  • UNII OJX2P28Y14
    A synthetic ester oil made from long-chain fatty acids. It works as an emollient and lubricant in topical formulations, helping the product spread smoothly on skin and improve texture.
  • UNII KEH0A3F75J
    Hexylene glycol is a clear liquid alcohol used as a solvent and preservative in medicines. It helps dissolve other ingredients and keeps the product stable during storage.
  • UNII UG00KM4WR7
    A plastic polymer used as a container material and film coating. It helps protect the medicine from moisture and air exposure during storage and shipping.
  • UNII YSE9PPT4TH
    Hyaluronate sodium is a natural carbohydrate that holds moisture. It's used in medicines as a lubricant, thickener, and moisture-retaining agent to improve texture and delivery of the active ingredient.
  • UNII 7D1YQ9Y5EZ
    Hydrogenated polybutene is a thick, wax-like ingredient made by chemically processing petroleum. It acts as a binder and lubricant, helping hold tablet ingredients together and allowing pills to slide smoothly during manufacturing and packaging.
  • UNII H1109Z9J4N
    A natural emulsifier derived from soybean oil. It helps mix oil and water-based ingredients together, ensuring even distribution of active ingredients throughout the medicine.
  • UNII 918X1OUF1E
    Isohexadecane is a synthetic hydrocarbon oil used as an emollient and solvent in topical medicines. It helps dissolve active ingredients and improves spreadability and absorption through the skin.
  • UNII 5CIT1X6U5V
    A naturally derived flavoring ingredient from melon fruit, used to add taste and aroma to make medicines more pleasant to take, especially for children.
  • UNII V8A1AW0880
    Mica is a naturally occurring mineral that's ground into fine powder. It's used in medicines as a colorant and anti-caking agent to improve appearance and prevent clumping in tablets or powders.
  • UNII JQZ6YM58U5
    A protein enzyme derived from white blood cells that breaks down harmful substances. In medicines, it may serve as an active biological component in certain therapeutic formulations rather than a traditional inactive filler or binder.
  • UNII V956696549
    N-Acetylglucosamine is a naturally occurring sugar compound derived from chitin. In medicines, it typically serves as a filler or binding agent to help hold tablet ingredients together and add bulk to the formulation.
  • UNII 5LKW3C543X
    A synthetic oily liquid derived from neopentyl glycol and heptanoic acid. It serves as an emollient and solvent in formulations, helping to dissolve or suspend active ingredients and improve the texture and spreadability of topical products.
  • UNII S013N99GR8
    Octyldodecyl myristate is a synthetic oil derived from myristic acid. It serves as an emollient and skin-conditioning agent in topical medicines, helping the product spread smoothly and keeping the skin soft.
  • UNII 2V16EO95H1
    Palmitic acid is a saturated fatty acid derived from plant and animal sources. It serves as an emulsifier and lubricant in medicines, helping ingredients mix smoothly and preventing sticking during manufacturing.
  • UNII YD01N1999R
    A waxy substance made from polyethylene glycol and stearic acid. It helps mix oil and water-based ingredients together and serves as an emulsifier and solubilizer in liquid and semi-solid medicines.
  • UNII XJ7052W897
    A synthetic ester derived from pentaerythritol, used primarily as an emollient and skin-conditioning agent in topical formulations. It helps soften and smooth the product's texture while improving how it spreads on skin.
  • UNII 4T6H12BN9U
    Petrolatum is a purified mineral oil-based jelly derived from petroleum. In medicines, it acts as an emollient, lubricant, and moisture barrier to soften skin, reduce friction, and help prevent water loss from formulations.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII Z47NNT4J11
    A synthetic plastic polymer used as a film-coating material on tablets and capsules. It helps protect the medicine, control how fast it dissolves, and improve appearance by creating a smooth, glossy outer layer.
  • UNII 6OZP39ZG8H
    Polysorbate 80 is a synthetic emulsifier derived from sorbitol and oleic acid. It helps mix oil and water-based ingredients together in medications and improves how the product disperses in the body.
  • UNII 1VPU26JZZ4
    Potassium sorbate is a salt derived from sorbic acid, a naturally occurring preservative. It prevents growth of mold, yeast, and some bacteria, extending the medicine's shelf life.
  • UNII 1K573LC5TV
    A mineral salt used in medications as an electrolyte source and to adjust the osmotic balance of liquid formulations, helping the medicine absorb properly in the body.
  • UNII 5965N8W85T
    Propanediol is a clear liquid organic compound derived from vegetable sources or synthesized chemically. It acts as a humectant to retain moisture, a solvent to dissolve active ingredients, and a preservative booster in liquid medications and supplements.
  • UNII 581437HWX2
    A synthetic oily liquid made from propylene glycol and fatty acids. It works as an emollient and solubilizer in medicines, helping dissolve active ingredients and improve how the product spreads or absorbs.
  • UNII 55X04QC32I
    A strong alkaline chemical used to adjust and maintain the pH balance of liquid medicines. It helps keep the medicine stable and ensures it stays effective during storage.
  • UNII PL360EPO9J
    Soy sterol is a plant-derived fat extracted from soybeans. It's used as an emulsifier and stabilizer to help keep oil and water mixed together and maintain the medicine's texture and consistency.
  • UNII 8I089SAH3T
    A carbohydrate powder extracted from potatoes. It serves as a filler to add bulk and volume to the tablet or capsule, and as a disintegrant to help the medicine break apart and release its active ingredient in your body.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
  • UNII B8WCK70T7I
    Trehalose is a natural sugar made from two glucose molecules linked together. It's used in medicines as a filler to add bulk, a sweetener for taste, and a stabilizer to help keep active ingredients effective during storage.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII TTV12P4NEE
    Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.
  • UNII C32PQ86DH4
    Zinc PCA is a zinc salt of pyroglutamic acid, a naturally occurring amino acid derivative. It's used in medications as a skin-conditioning agent and to help maintain product stability and texture in topical formulations.

54 inactive ingredients listed in the exact product block matched to this NDC.

The official label also stateswater\aqua\eau • neopentyl glycol diheptanoate • cetyl alcohol • glycerin • butyloctyl salicylate • pentaerythrityl tetraethylhexanoate • polyethylene • di-c12-15 alkyl fumarate • petrolatum • hydrogenated lecithin • butylene glycol • propanediol • hydrogenated polyisobutene • octyldodecyl myristate • hexyldecyl stearate • behenyl alcohol • cucumis melo (melon) fruit extract • polygonum aviculare extract • myrtus communis leaf extract • laminaria digitata extract • acetyl hexapeptide-8 • tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate • lactoperoxidase • glucose oxidase • cholesterol • propylene glycol dicaprylate • aminopropyl ascorbyl phosphate • sodium hyaluronate • glucose • algae extract • artemia extract • acetyl glucosamine • sigesbeckia orientalis (st. paul's wort) extract • glyceryl stearate • persea gratissima (avocado) oil • dimethicone • c12-16 alcohols • trehalose • ethylhexylglycerin • peg-100 stearate • caffeine • palmitic acid • glycine soja (soybean) sterols • caprylyl glycol • isohexadecane • polymethyl methacrylate • trifluoroacetyl tripeptide-2 • tocopheryl acetate • zinc pca • polysilicone-11 • polysorbate 80 • yeast extract\faex\extrait de levure • potato starch modified • decarboxy carnosine hcl • xanthan gum • fragrance (parfum) • sodium hydroxide • potassium sulfate • acrylamide/sodium acryloyldimethyltaurate copolymer • dextran • hexylene glycol • disodium edta • bht • potassium sorbate • phenoxyethanol • red 4 (ci 14700) • mica • titanium dioxide (ci 77891) <iln44790>

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerESTEE LAUDER INC
FDA applicationM020 (OTC MONOGRAPH DRUG)
Labeler code11559
First marketedNov 2018
Product typeHuman Otc Drug
Portfolio23 products on file

More NDCs from ESTEE LAUDER INC labeler code 11559

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 30 words ▾

Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ) decreases the risk of skin cancer and early skin aging caused by the sun

⏱️ Dosage and Administration 98 words ▾

Directions For sunscreen use: apply liberally and evenly 15 minutes before sun exposure reapply at least every two hours use a water resistant sunscreen if swimming or sweating Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m. – 2 p.m. wear long-sleeved shirts, pants, hats and sunglasses children under 6 months of age: ask a doctor

⚠️ Warnings 56 words ▾

Warnings For external use only Do not use on damaged or broken skin When using this product keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if rash occurs Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 14 words ▾

Other information protect the product in this container from excessive heat and direct sun

🧪 Active Ingredient 12 words ▾

Active ingredients Purpose Avobenzone 3.0% Sunscreen Octisalate 4.5% Sunscreen Octocrylene 2.7% Sunscreen

🧪 Inactive Ingredients 218 words ▾

Inactive ingredients water\aqua\eau • neopentyl glycol diheptanoate • cetyl alcohol • glycerin • butyloctyl salicylate • pentaerythrityl tetraethylhexanoate • polyethylene • di-c12-15 alkyl fumarate • petrolatum • hydrogenated lecithin • butylene glycol • propanediol • hydrogenated polyisobutene • octyldodecyl myristate • hexyldecyl stearate • behenyl alcohol • cucumis melo (melon) fruit extract • polygonum aviculare extract • myrtus communis leaf extract • laminaria digitata extract • acetyl hexapeptide-8 • tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate • lactoperoxidase • glucose oxidase • cholesterol • propylene glycol dicaprylate • aminopropyl ascorbyl phosphate • sodium hyaluronate • glucose • algae extract • artemia extract • acetyl glucosamine • sigesbeckia orientalis (st. paul's wort) extract • glyceryl stearate • persea gratissima (avocado) oil • dimethicone • c12-16 alcohols • trehalose • ethylhexylglycerin • peg-100 stearate • caffeine • palmitic acid • glycine soja (soybean) sterols • caprylyl glycol • isohexadecane • polymethyl methacrylate • trifluoroacetyl tripeptide-2 • tocopheryl acetate • zinc pca • polysilicone-11 • polysorbate 80 • yeast extract\faex\extrait de levure • potato starch modified • decarboxy carnosine hcl • xanthan gum • fragrance (parfum) • sodium hydroxide • potassium sulfate • acrylamide/sodium acryloyldimethyltaurate copolymer • dextran • hexylene glycol • disodium edta • bht • potassium sorbate • phenoxyethanol • red 4 (ci 14700) • mica • titanium dioxide (ci 77891) <iln44790>

🎯 Purpose 12 words ▾

Active ingredients Purpose Avobenzone 3.0% Sunscreen Octisalate 4.5% Sunscreen Octocrylene 2.7% Sunscreen

📄 Do Not Use 8 words ▾

Do not use on damaged or broken skin

📄 When Using This Product 13 words ▾

When using this product keep out of eyes. Rinse with water to remove.

📄 Stop Use and Ask a Doctor If 9 words ▾

Stop use and ask a doctor if rash occurs

📄 Keep Out of Reach of Children 21 words ▾

Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

📄 Package Label / Principal Display Panel 37 words ▾

PRINCIPAL DISPLAY PANEL - 50 ml Jar Carton ESTĒE LAUDER Resilience Multi-Effect Tri-Peptide Face and Neck Creme Broad Spectrum SPF 15 Normal/Combination Skin NET WT.

1.7OZ./50 ml e Principal Display Panel - 50 ml Jar Carton

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for AVOBENZONE, OCTISALATE, and OCTOCRYLENE — the ingredient across all brands.

Top reported reactions

Acne258
Skin Burning Sensation236
Dry Skin217
Erythema178
Skin Irritation148
Skin Exfoliation90
Hypersensitivity70

Reporter sex

1,001 reports
Female · 100%
Reports over time (by year) — tap or hover for the count & year
2022 2023 2024 2026 757 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Does this product come in other package sizes?
Yes — the FDA directory lists 5 other package presentations of this same product, including 1 jar (11559-0052-02), 1 jar (11559-0052-03), 1 jar (11559-0052-04). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
ESTEE LAUDER INC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 11559-0050-01 · ESTEE 11559-0053-01 · ESTEE →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.