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Esomeprazole magnesium 20 mg Capsule, Delayed Release, 14-count — NDC 21130-0718-45 package photo

Esomeprazole magnesium 20 mg Capsule, Delayed Release, 14-count

by BETTER LIVING BRANDS, LLC · 1 BOTTLE in 1 CARTON (21130-718-45) / 14 CAPSULE, DELAYED RELEASE in 1 BOTTLE
NDC 21130-0718-45
🏷️ FDA NDC (as labeled) 21130-718-45 billing pads the product segment with a zero
This package
Contains14-count Pack sizes3 compare ↓
Also priced by: Part D plans $0.3386/unit — full pricing hub ↓
Also comes in: 14 capsules 21130-0718-41 14 capsules 21130-0718-82
OTC Generic On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Other active recalls for Esomeprazole Magnesium (different manufacturers) — 3 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · May 13, 2025 — Failed Impurities/Degradation Specifications: Out-of-Specification test results obtained for any individual unknown degradation product during Related Compounds testing during long term stability. (Zydus Pharmaceuticals (USA) Inc) · FDA recall D-0443-2025
Class II · May 13, 2025 — Failed Impurities/Degradation Specifications: Out-of-Specification test results obtained for any individual unknown degradation product during Related Compounds testing during long term stability. (Zydus Pharmaceuticals (USA) Inc) · FDA recall D-0442-2025
Class III · Nov 14, 2024 — Labeling: Not Elsewhere Classified - Wrong NDC number (Zydus Pharmaceuticals (USA) Inc) · FDA recall D-0102-2025
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗

🆔 Identity & classification

FDA NDC (as labeled) 21130-718-45
Product NDC 21130-718
11-digit billing NDC 21130071845
RxCUI 606726
UNII R6DXU4WAY9
UPC 0321130277033
Application # ANDA217264
SPL Set ID eb4c1cac-89a2-c040-e053-2995a90ae1cd
Established class (EPC) Proton Pump Inhibitor
Mechanism of action Cytochrome P450 2C19 Inhibitors; Proton Pump Inhibitors
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2023-10-20
Route ORAL
Dosage form CAPSULE, DELAYED RELEASE
Substance ESOMEPRAZOLE MAGNESIUM
Why two NDCs? The FDA registers this code as 21130-718-45 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 21130-0718-45. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Proton Pump Inhibitor class.

Pharmacologic class Proton Pump Inhibitor
Drug family (ATC) Proton pump inhibitors, Propionic acid derivatives
How it works Proton Pump Inhibitors, Cytochrome P450 2C19 Inhibitors
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerBETTER LIVING BRANDS, LLC
Application holderMARKSANS PHARMA LTD
FDA applicationANDA217264 (ANDA)
Labeler code21130
First marketedOct 2023
Product typeHuman Otc Drug
Portfolio84 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • It's blocking the 'acid pump' — a tiny enzyme in your stomach lining that releases acid. By shutting down that pump, esomeprazole cuts the amount of acid your stomach produces, giv...
  • What is esomeprazole actually doing in my body?
  • Before eating is best — ideally at least 30 minutes before your first meal of the day. Food can reduce how much of the medicine your body absorbs by nearly half, so timing really d...
  • Should I take it before or after eating?
📖 Read our full Esomeprazole guide →
9
Nutrient depletion considerations

Esomeprazole Magnesium may be associated with lower levels of 9 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Esomeprazole Magnesium nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color purple
ShapeCapsule
Imprint75
Size14 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 92RU3N3Y1O
    Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
  • UNII H3R47K3TBD
    FD&C Blue No. 1 is a synthetic blue dye approved for use in foods and medicines. It serves as a colorant to give the medication its distinctive appearance and help with product identification.
  • UNII PN2ZH5LOQY
    A synthetic red dye approved by the FDA for use in foods, medicines, and cosmetics. It serves as a colorant to make tablets, capsules, and liquids visually distinctive for product identification.
  • UNII EX438O2MRT
    Ferric oxide yellow is a naturally occurring iron compound used as a colorant in medications. It gives tablets, capsules, and other forms a yellow or golden hue for identification and appearance.
  • UNII XM0M87F357
    A dark iron oxide compound that gives medicines their black or dark color. It's used as a colorant in tablets and capsules to help identify the product and make it visually distinctive.
  • UNII 2G86QN327L
    Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
  • UNII 230OU9XXE4
    A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
  • UNII 9XZ8H6N6OH
    A plant-based cellulose derivative used as a binder to hold tablet ingredients together, a thickener in liquids, and a coating agent to control how fast the medicine dissolves.
  • UNII 3NXW29V3WO
    Hypromellose is a plant-based thickener made from cellulose. It's used in medicines as a binder to hold ingredients together, a coating for tablets, and a thickener for liquids.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII 74G4R6TH13
    A synthetic polymer made by combining two plastic-like chemicals. It forms a coating on tablets or capsules that dissolves at a specific point in the digestive tract, controlling where and when the medicine releases.
  • UNII 6OZP39ZG8H
    Polysorbate 80 is a synthetic emulsifier derived from sorbitol and oleic acid. It helps mix oil and water-based ingredients together in medications and improves how the product disperses in the body.
  • UNII WZH3C48M4T
    Potassium hydroxide is a strong alkaline chemical used in medicines to adjust and maintain the pH level of liquid formulations, helping keep the product stable and the active ingredients effective.
  • UNII 46N107B71O
    Shellac is a natural resin secreted by the lac beetle. It's used as a coating on tablets and capsules to control how quickly the medicine dissolves and to improve appearance and stability.
  • UNII 368GB5141J
    A detergent and foaming agent derived from coconut or palm oil. In medications, it helps break down and mix oil and water-based ingredients, aids in tablet disintegration, and improves how the drug dissolves and spreads in the mouth or digestive system.
  • UNII C151H8M554
    A natural sugar derived from sugar cane or sugar beets. It's used as a sweetener, filler, and binder to improve taste, add bulk, and help hold tablet or capsule ingredients together.
  • UNII 7SEV7J4R1U
    A powder made from a naturally occurring mineral. In medicines, talc works as a glidant and anti-caking agent, helping tablets and capsules flow smoothly during manufacturing and preventing clumping.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
  • UNII 8Z96QXD6UM
    Triethyl citrate is a clear liquid derived from citric acid. It acts as a plasticizer and solvent in tablet coatings and film formulations, helping the coating remain flexible and adhere properly to the medicine.

19 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesInactive ingredients black iron oxide, eudragit, FD&C blue 1, FD&C red 3, ferric oxide yellow, gelatin, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, magnesium stearate, polysorbate 80, potassium hydroxide, shellac, simethicone, sodium lauryl sulfate, sugar spheres, talc, titanium dioxide, triethyl citrate.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · Q2 2026 $0.3386 $4.74 / 14 capsules
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Esomeprazole Magnesium 20 mg 00378-2350-77 Mylan 90 capsules $0.153 AB Availability likely —
Esomeprazole Magnesium 20 mg 16714-0979-01 NorthStar 30 capsules $0.153 AB Availability likely —
Esomeprazole Magnesium 20 mg 31722-0664-10 Camber 1000 capsules $0.153 AB Availability likely —
Esomeprazole magnesium 20 mg 43547-0001-03 Solco 30 capsules $0.153 AB Availability likely —
Esomeprazole Magnesium 20 mg 43598-0509-10 Dr. 1000 capsules $0.153 AB Availability likely —
Esomeprazole Magnesium 20 mg 62175-0820-32 Lannett 30 capsules $0.153 AB Availability likely —
Esomeprazole magnesium 20 mg 63304-0734-10 Sun 1000 capsules $0.153 AB Availability likely —
Esomeprazole magnesium 20 mg 64980-0632-03 Rising 30 capsules $0.153 AB Availability likely —
esomeprazole magnesium 20 mg 68382-0441-06 Zydus 30 capsules $0.153 AB Availability likely —
Esomeprazole Magnesium 20 mg 70069-0814-10 Somerset 1000 capsules $0.153 AB Availability likely —
esomeprazole magnesium 20 mg 70377-0055-11 Biocon 30 capsules $0.153 AB Availability likely —
Esomeprazole Magnesium 20 mg 82009-0033-10 Quallent 1000 capsules $0.153 AB Availability likely —
Esomeprazole Magnesium 20 mg 68462-0390-10 Glenmark 1000 capsules $0.177 — FDA listed —
Esomeprazole 20 mg 51660-0027-14 Ohm 14 capsules $0.343 — FDA listed —
Good Sense Esomeprazole Magnesium 20 mg 00113-0898-01 L. 14 capsules $0.349 — Availability likely —
Esomeprazole Magnesium 20 mg 16571-0880-41 Rising 14 capsules $0.349 — Availability likely —
Good Neighbor Pharmacy Esomeprazole Magnesium 20 mg 46122-0641-04 Amerisource 14 capsules $0.349 — Availability likely —
Esomeprazole Magnesium 20 mg 46122-0736-03 Amerisource 14 capsules $0.349 — Availability likely —
Esomeprazole Magnesium 20 mg 69230-0320-31 Camber 14 capsules $0.349 — Availability likely —
leader esomeprazole magnesium 20 mg 70000-0727-01 Cardinal 14 capsules $0.349 — Availability likely —
Esomeprazole Magnesium 20 mg 70000-0731-01 LEADER/ 14 capsules $0.349 — Availability likely —
Foster and Thrive Acid Reducer 20 mg 70677-1099-01 Strategic 14 capsules $0.349 — Availability likely —
Esomeprazole Magnesium 20 mg 43598-0407-27 Dr. 14 capsules $0.349 — Availability likely —
Esomeprazole Magnesium 20 mg 63868-0425-14 CHAIN 14 capsules $0.361 — FDA listed —
Nexium 20 mg 00186-5020-31 AstraZeneca 30 capsules $8.781 AB Availability likely —
good sense esomeprazole magnesium 20 mg 00113-0651-01 L. 14 capsules — — Discontinued —
good sense esomeprazole magnesium 20 mg 00113-2022-02 L. 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 00363-0508-05 WALGREEN 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 00363-0772-14 WALGREENS 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 00363-1699-01 Walgreen 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 00363-3298-01 Walgreens 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 00363-7223-01 Walgreen 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed Release 20 mg 00363-7810-41 WALGREENS 14 capsules — — FDA listed —
Nexium 24HR 20 mg 00573-2450-02 Haleon 2 capsules — — FDA listed —
Nexium 24HR ClearMinis 20 mg 00573-2452-02 Haleon 2 capsules — — FDA listed —
Up and Up Esomeprazole Magnesium 20 mg 11673-0753-01 Target 14 capsules — — FDA listed —
up and up esomeprazole magnesium 20 mg 11673-0898-01 Target 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 11822-0024-05 Rite 1 capsule — — FDA listed —
esomeprazole magnesium 20 mg 11822-0898-01 Rite 14 capsules — — Discontinued —
signature care esomeprazole magnesium 20 mg 21130-0088-01 Safeway 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 21130-0100-05 Better 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 21130-0257-41 BETTER 14 capsules — — FDA listed —
signature care esomeprazole magnesium 20 mg 21130-0714-01 Safeway 14 capsules — — Discontinued —
Esomeprazole magnesium 20 mgthis 21130-0718-45 BETTER 14 capsules — — FDA listed —
Esomeprazole 20 mg 21130-0926-14 Safeway, 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed-Release Capsules, 20 mg 25000-0075-76 MARKSANS 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed-Release 20 mg (OTC) 25000-0088-76 MARKSANS 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed Release 20 mg mini 25000-0096-76 MARKSANS 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed-Release 20 mg mini 25000-0112-76 MARKSANS 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 30142-0261-14 The 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 30142-0273-01 Kroger 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 30142-0528-14 KROGER 14 capsules — — FDA listed —
esomeprazole 20 mg 30142-0989-28 THE 14 capsules — — FDA listed —
esomeprazole 20 mg 33342-0306-07 Macleods 30 capsules — — FDA listed —
topcare esomeprazole magnesium 20 mg 36800-0627-01 Topco 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 37808-0115-14 HEB 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 37808-0364-14 H 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 37808-0719-01 H 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 41250-0727-01 Meijer 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 41250-0900-01 Meijer 14 capsules — — FDA listed —
careone esomeprazole magnesium 20 mg 41520-0727-01 American 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 42507-0774-42 HyVee 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 42507-0898-42 HyVee 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 43598-0067-42 Dr. 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 43598-0327-27 Dr. 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 43598-0812-14 Dr. 14 capsules — — Discontinued —
Esomeprazole Magnesium 20 mg 43598-0926-28 Dr. 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 45865-0163-30 Medsource 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 46122-0821-59 Amerisource 14 capsules — — FDA listed —
equate esomeprazole magnesium 20 mg 49035-0921-14 Wal-Mart 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 49035-0980-05 Wal-Mart 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 49483-0718-41 TIME 14 capsules — — FDA listed —
Nexium 24HR 20 mg 50090-1492-00 A-S 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 50090-6198-00 A-S 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 50090-6213-00 A-S 30 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 51316-0220-01 CVS 14 capsules — — FDA listed —
Esomeprazole 20 mg 51316-0715-14 CVS 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 51407-0742-10 Golden 1000 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 53041-0666-07 Guardian 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 53943-0039-14 DISCOUNT 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 53943-0527-14 Discount 14 capsules — — FDA listed —
Exchange Select Esomeprazole Magnesium 20 mg 55301-0898-01 Army 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 55319-0051-03 Family 14 capsules — — FDA listed —
dg health esomeprazole magnesium 20 mg 55910-0250-01 Dolgencorp, 14 capsules — — FDA listed —
DG Health Esomeprazole Magnesium 20 mg 55910-0593-01 Dolgencorp 14 capsules — — FDA listed —
dg health esomeprazole magnesium 20 mg 55910-0640-01 Dolgencorp 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 56062-0020-06 Publix 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 56062-0898-01 Publix 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 57483-0225-42 INNOVUS 14 capsules — — FDA listed —
Esomeprazole 20 mg 57483-0900-42 INNOVUS 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0707-05 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0809-05 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0822-05 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0846-05 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0896-62 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 59651-0561-50 Aurobindo 50000 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 60000-0109-03 Ahold 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 60687-0934-21 American 1 capsule — AB FDA listed —
Esomeprazole Magnesium 20 mg 63187-0964-30 Proficient 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 63941-0971-03 Best 14 capsules — — FDA listed —
Esomeprazole 20 mg 63941-0999-14 VALU 14 capsules — — FDA listed —
kirkland signature esomeprazole magnesium 20 mg 63981-0898-03 Costco 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 64980-0664-19 Rising 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 65862-0783-01 Aurobindo 100 capsules — AB FDA listed —
Esomeprazole magnesium 20 mg 67877-0478-05 Ascend 500 capsules — AB FDA listed —
Esomeprazole magnesium 20 mg 67877-0571-05 Ascend 500 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 68071-3419-06 NuCare 60 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 68071-3735-03 NuCare 30 capsules — AB FDA listed —
members mark esomeprazole magnesium 20 mg 68196-0898-03 Sam's 14 capsules — — FDA listed —
berkley and jensen heartburn treatment 20 mg 68391-0898-03 BJWC 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 68788-4014-09 Preferred 90 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 68788-8511-01 Preferred 100 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 69168-0472-14 Allegiant 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 69434-0012-01 Zhejiang 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 69618-0073-42 Reliable 14 capsules — — FDA listed —
Riopan 20 mg 69729-0791-14 OPMX 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 69842-0248-06 CVS 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 69842-0703-01 CVS 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 69842-0898-01 CVS 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 69844-0115-01 Graviti 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 70000-0738-01 LEADER/ 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 70010-0133-03 Granules 30 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 70771-1493-00 Zydus 1000 capsules — AB FDA listed —
Esomeprazole magnesium 20 mg 71205-0706-30 Proficient 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 71335-0807-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 71335-1170-01 Bryant 30 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 71335-1368-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 71335-2018-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 71335-2505-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole magnesium 20 mg 71335-9678-01 Bryant 30 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 71335-9713-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole DR 20 mg 72189-0381-30 Direct_Rx 30 capsules — AB FDA listed —
Basic Care Esomeprazole Magnesium 20 mg 72288-0560-01 Amazon.com 14 capsules — — FDA listed —
basic care esomeprazole magnesium 20 mg 72288-0700-03 Amazon.com 14 capsules — — FDA listed —
basic care esomeprazole magnesium 20 mg 72288-0898-01 Amazon.com 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 72476-0500-03 Retail 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 72559-0011-06 LITTLE 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 72657-0124-42 GLENMARK 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 72657-0127-42 GLENMARK 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 72789-0352-30 PD-Rx 30 capsules — AB FDA listed —
Esomeprazole 20 mg 73581-0013-42 YYBA 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 73581-0014-42 YYBA 42 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 76420-0226-30 Asclemed 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 76420-0904-00 Asclemed 1000 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 79481-0411-00 Meijer, 14 capsules — — FDA listed —
equate esomeprazole magnesium 20 mg 79903-0293-42 WALMART 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 79903-0382-42 Walmart 14 capsules — — FDA listed —
Equate Esomeprazole Magnesium 20 mg 79903-0419-42 WALMART 14 capsules — — FDA listed —
Esomeprazole Magnesium DR 20 mg 80425-0111-01 Advanced 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 80425-0419-01 Advanced 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 80425-0420-01 Advanced 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 83324-0200-14 CHAIN 14 capsules — — FDA listed —
24 HOUR Esomeprazole Magnesium 20 mg 85828-0718-45 Grocery 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 37808-0646-41 H-E-B 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 50090-7990-00 A-S 30 capsules — AB FDA listed —
Esomeprazole 20 mg 57896-0740-42 GERI-CARE 14 capsules — — FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2023
On the market since
Oct 2023
📍
2026
Currently FDA-listed
3 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📊 Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Esomeprazole Magnesium — the program that covers self-administered drugs. 18 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Esomeprazole Magnesium. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$26.52M
Claims incl. refills
740.1K
Beneficiaries
544.7K
Spend / beneficiary
$48.68
Spend / claim
$35.83
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
21130-0718-41 3 BOTTLE in 1 CARTON (21130-718-41) / 14 CAPSULE, DELAYED RELEASE in 1 BOTTLE 2023-10-20 Active
21130-0718-45 You're viewing this 1 BOTTLE in 1 CARTON (21130-718-45) / 14 CAPSULE, DELAYED RELEASE in 1 BOTTLE 2023-10-20 Active
21130-0718-82 2 CARTON in 1 CARTON (21130-718-82) / 14 CAPSULE, DELAYED RELEASE in 1 CARTON 2023-11-13 Active

Pack size FAQ

What quantity is in NDC 21130-0718-45?
NDC 21130-0718-45 is a 14-count package — 1 bottle in 1 carton / 14 capsule, delayed release in 1 bottle.
What NDC number is used to bill for this package of Esomeprazole magnesium 20 mg Capsule, Delayed Release?
Bill NDC 21130-0718-45 — the 11-digit billing format is 21130071845. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 21130-718-45, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 21130-0718-45, written without dashes as 21130071845. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 21130-0718-45, the first segment (21130) is the labeler code FDA assigned to BETTER LIVING BRANDS, LLC; the middle segment (0718) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (45) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by BETTER LIVING BRANDS, LLC. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 14 capsules (21130-0718-41), 14 capsules (21130-0718-82). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
BETTER LIVING BRANDS, LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 29 words ▾

Uses treats frequent heartburn (occurs 2 or more days a week) not intended for immediate relief of heartburn; this drug may take 1 to 4 days for full effect

⏱️ Dosage and Administration 143 words ▾

Directions adults 18 years of age and older this product is to be used once a day (every 24 hours), every day for 14 days may take 1 to 4 days for full effect 14-Day Course of Treatment swallow 1 capsule with a glass of water before eating in the morning take every day for 14 days do not take more than 1 capsule a day swallow whole. Do not crush or chew capsules. do not use for more than 14 days unless directed by your doctor Repeated 14-Day Courses (if needed) you may repeat a 14-day course every 4 months do not take for more than 14 days or more often than every 4 months unless directed by a doctor children under 18 years of age: ask a doctor before use.

Heartburn in children may sometimes be caused by a serious condition.

⚠️ Warnings 37 words ▾

Warnings Allergy alert Do not use if you are allergic to esomeprazole Esomeprazole may cause severe skin reactions. Symptoms include: -skin reddening -blisters -rash If an allergic reaction occurs, stop use and seek medical attention right away.

🧪 Active Ingredient 18 words ▾

Active ingredient (in each capsule) Esomeprazole 20 mg (Each delayed-release capsule corresponds to 22.3 mg esomeprazole magnesium trihydrate)

🧪 Inactive Ingredients 39 words ▾

Inactive ingredients black iron oxide, eudragit, FD&C blue 1, FD&C red 3, ferric oxide yellow, gelatin, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, magnesium stearate, polysorbate 80, potassium hydroxide, shellac, simethicone, sodium lauryl sulfate, sugar spheres, talc, titanium dioxide, triethyl citrate.

🎯 Purpose 3 words ▾

Purpose Acid reducer

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 21130-0717-06 · BETTER 21130-0719-78 · Safeway →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.