Home › NDC Lookup › Ingredients › Chloroxylenol › 21749-0521-53
GOJO Antimicrobial Foam Handwash with PCMX CHLOROXYLENOL .005 mg/mL Liquid, 535 mL — NDC 21749-0521-53 package photo

GOJO Antimicrobial Foam Handwash with PCMX CHLOROXYLENOL .005 mg/mL Liquid, 535 mL

by GOJO Industries, Inc. · 535 mL in 1 BOTTLE (21749-521-53)
NDC 21749-0521-53
🏷️ FDA NDC (as labeled) 21749-521-53 billing pads the product segment with a zero
This package
Contains535 mL Pack sizes4 compare ↓
Also comes in: 700 ml 21749-0521-97 1200 ml 21749-0521-89 1250 ml 21749-0521-90
OTC Discontinued Non-controlled ⚠ Discontinued by firm
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

🆔 Identity & classification

FDA NDC (as labeled) 21749-521-53
Product NDC 21749-521
11-digit billing NDC 21749052153
RxCUI 436367
UNII 0F32U78V2Q
Application # 505G(a)(3)
SPL Set ID 1f531296-f826-4354-919a-ed356d70e4ba
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Discontinued by firm
Marketing start 2014-07-30
Route TOPICAL
Dosage form LIQUID
Substance CHLOROXYLENOL
Why two NDCs? The FDA registers this code as 21749-521-53 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 21749-0521-53. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Phenol and derivatives class.

Drug family (ATC) Phenol and derivatives
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerGOJO Industries, Inc.
FDA application505G(a)(3) (OTC MONOGRAPH DRUG)
Labeler code21749
First marketedJul 2014
Product typeHuman Otc Drug
Portfolio79 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

GOJO Antimicrobial Foam Handwash is a liquid topical product applied to the skin as a hand cleanser. It contains chloroxylenol, an antimicrobial agent commonly used in over-the-counter antiseptic soaps and washes. This product is marketed under FDA's OTC monograph rules for antimicrobial hand cleansers, meaning it follows established safety and use guidelines for this category rather than undergoing individual FDA review. Chloroxylenol is typically used to reduce bacteria on the skin during handwashing.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
  • UNII 9DBA0SBB0L
    A synthetic red dye derived from coal tar used as a colorant in medicines and cosmetics. It gives tablets, capsules, and liquids their red or pink appearance for identification and visual appeal.
  • UNII E107L85C40
    Dipropylene glycol is a clear liquid made from propylene glycol. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
  • UNII MP1J8420LU
    A salt derived from edetic acid that binds to trace metals in medicines. It serves as a chelating agent and preservative to prevent metal-catalyzed breakdown of the drug and extend shelf life.
  • UNII 3P3ONR6O1S
    A synthetic green dye approved by the FDA for use in medicines and foods. It serves as a colorant to make the pill or liquid visually distinctive and help with product identification.
  • UNII ND2M416302
    Isopropyl alcohol is a clear liquid solvent derived from petroleum. In medicines, it dissolves active ingredients and other components, helps the product flow smoothly, and aids in sterilization during manufacturing.
  • UNII 33X04XA5AT
    Lactic acid is a naturally occurring organic acid derived from milk or plant sources. It lowers and maintains pH in formulations, helps preserve the product, and can enhance ingredient stability and absorption.
  • UNII 1160N9NU9U
    Lauric acid is a natural saturated fatty acid derived from coconut or palm oil. It serves as an emulsifier and lubricant in medicines, helping ingredients mix smoothly and preventing sticking during manufacturing.
  • UNII A2I8C7HI9T
    Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
  • UNII 5KV86114PT
    A chemical compound used in medicines as a pH buffer and neutralizing agent. It helps maintain the proper acidity level in liquid formulations to improve stability and make the medicine easier to take.
  • UNII 1S66E28KXA
    Poloxamer 124 is a synthetic polymer that acts as a surfactant and solubilizer in medicines. It helps dissolve and stabilize active ingredients, particularly in liquid formulations and gels.
  • UNII Z8IX2SC1OH
    Propylparaben is a chemical preservative used to prevent bacterial and fungal growth in medicines and personal care products. It helps extend shelf life and maintain product safety during storage.
  • UNII 4VON5FNS3C
    Sodium metabisulfite is a preservative derived from sulfur compounds. It prevents microbial growth and oxidation in medicines, helping extend shelf life and maintain product stability.
  • UNII 0YPR65R21J
    Sodium sulfate is a mineral salt used in pharmaceuticals as a filler and diluent. It helps provide bulk and stability to tablets and capsules while remaining inert in the body.
  • UNII VTK01UQK3G
    Sodium sulfite is a salt preservative derived from sulfur. It prevents discoloration and microbial growth in medicines, helping keep products stable during storage.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

16 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesWater (Aqua), Alcohol, Lauric Acid, Ethanolamine, Dipropylene Glycol, Lactic Acid, Poloxamer 124, Isopropyl Alcohol, Sodium Metabisulfite, Sodium Sulfite, Tetrasodium EDTA, Sodium Sulfate, Fragrance (Parfum), Methylparaben, Propylparaben, Green 3 (CI 42053), Red 33 (CI 17200)

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 700 ml 1200 ml 1250 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
MICRELL Antibacterial Foam Handwash .005 mg/mL 21749-0095-22 GOJO 200 ml — — Discontinued —
GOJO Antimicrobial Foam Handwash with PCMX .005 mg/mLthis 21749-0521-53 GOJO 535 ml — — Discontinued —
PROVON Foaming Antimicrobial Handwash with PCMX .005 mg/mL 21749-0541-20 GOJO 2000 ml — — Discontinued —
Ecolab Keystone 5 mg/mL 47593-0465-25 Ecolab 800 ml — — FDA listed —
Ecolab 5.2 mg/mL 47593-0501-11 Ecolab 3780 ml — — FDA listed —
Ecolab Inc. 5 mg/mL 47593-0503-41 Ecolab 750 ml — — Discontinued —
Ecolab Clean Force 5 mg/mL 47593-0515-25 Ecolab 800 ml — — FDA listed —
Members Mark 5 mg/mL 47593-0573-11 Ecolab 3780 ml — — FDA listed —
Kay Foaming Antibacterial Handsoap PLUS 5 mg/mL 47593-0659-70 Ecolab 1200 ml — — FDA listed —
McD Foaming Antibacterial Handsoap 5 mg/mL 47593-0669-59 Ecolab 1250 ml — — FDA listed —
Kay QSR Antibacterial Handsoap 5 mg/mL 47593-0671-11 Ecolab 3800 ml — — FDA listed —
Qsr Foaming Antibacterial Handsoap 5 mg/mL 47593-0672-41 Ecolab 750 ml — — FDA listed —
Ecolab Foaming Antibacterial Handsoap 5 mg/mL 47593-0678-59 Ecolab 1250 ml — — FDA listed —
Rushing Foaming Antibacterial Handsoap 5 mg/mL 47593-0682-59 Ecolab 1250 ml — — FDA listed —
Kay RTU Foaming AB HandSoap 5 mg/mL 47593-0693-70 Ecolab 1200 ml — — FDA listed —
Fortress Foaming Antibacterial HandSoap 5 mg/mL 47593-0694-41 Ecolab 750 ml — — FDA listed —
CleanGenic Antibacterial Foam Hand 5 mg/.001L 60933-0050-00 Fuller 1 l — — FDA listed —
Simple Hygiene Antibacterial Foam Hand 5 mg/mL 60933-0106-01 Fuller 3790 ml — — FDA listed —
Sierra Soft Antibacterial Wash 5 g/L 70415-0001-01 CWGC 1 l — — FDA listed —
Sierrasoft Clear Antibacterial Wash Foam .5 g/100mL 70415-0901-01 CWGC 1000 ml — — FDA listed —
Hillyard Citrus Fresh Antimicrobial Foaming .5 g/100mL 76402-0408-02 Hillyard 1000 ml — — FDA listed —
ProPower Originals Antimicrobial Foaming So ap .005 mg/mL 66294-0521-40 BUNZL 1200 ml — — FDA listed —
PURELL Food Processing HEALTHY SP 0.5pct PCMX Antimicrobial E2 Foam Handwash .005 mg/mL 21749-0528-20 GOJO 2000 ml — — Discontinued —
ADVANTAGE CHEMICAL Premium Antibacterial Foaming Hand So ap .005 mg/mL 71912-0521-42 Advantage 1250 ml — — FDA listed —
PURELL HEALTHY SP PCMX E2 Antimicrobial Foam .005 mg/mL 21749-0531-40 GOJO 1200 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2014
On the market since
Jul 2014
📍
2026
Currently FDA-listed
12 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
21749-0521-53 You're viewing this 535 mL in 1 BOTTLE (21749-521-53) 2014-07-30 Discontinued by firm
21749-0521-89 1200 mL in 1 BOTTLE (21749-521-89) 2014-07-30 Discontinued by firm
21749-0521-90 1250 mL in 1 BOTTLE (21749-521-90) 2014-07-30 Active
21749-0521-97 700 mL in 1 BOTTLE (21749-521-97) 2014-07-30 Discontinued by firm

You're viewing the smallest of 4 pack sizes for this product.

Pack size FAQ

What quantity is in NDC 21749-0521-53?
NDC 21749-0521-53 contains 535 mL — 535 ml in 1 bottle.
What is the difference between NDC 21749-0521-53 and NDC 21749-0521-97?
Both are GOJO Antimicrobial Foam Handwash with PCMX CHLOROXYLENOL .005 mg/mL Liquid — the drug itself is identical. NDC 21749-0521-53 is the 535 mL package, while NDC 21749-0521-97 is the 700 ml package.
What NDC number is used to bill for this package of GOJO Antimicrobial Foam Handwash with PCMX CHLOROXYLENOL .005 mg/mL Liquid?
Bill NDC 21749-0521-53 — the 11-digit billing format is 21749052153. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 21749-521-53, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 21749-0521-53, written without dashes as 21749052153. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 21749-0521-53, the first segment (21749) is the labeler code FDA assigned to GOJO Industries, Inc.; the middle segment (0521) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (53) identifies this exact package size and type. Together they name one specific package of one specific product.
Does this product come in other package sizes?
Yes — the FDA directory lists 3 other package presentations of this same product, including 700 ml (21749-0521-97), 1200 ml (21749-0521-89), 1250 ml (21749-0521-90). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
GOJO Industries, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 13 words ▾

Use Handwash to help decrease bacteria on the skin Recommended for repeated use

⏱️ Dosage and Administration 17 words ▾

Directions Wet hands. Apply product and thoroughly cover hands with lather. Rinse well and dry hands completely.

⚠️ Warnings 58 words ▾

Warnings For external use only When using this product do not use in or near the eyes. In case of contact, rinse eyes thoroughly with water. Stop use and ask a doctor if irritation or rash appears and lasts Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 4 words ▾

Active ingredient Chloroxylenol 0.5%

🧪 Inactive Ingredients 36 words ▾

Inactive ingredients Water (Aqua), Alcohol, Lauric Acid, Ethanolamine, Dipropylene Glycol, Lactic Acid, Poloxamer 124, Isopropyl Alcohol, Sodium Metabisulfite, Sodium Sulfite, Tetrasodium EDTA, Sodium Sulfate, Fragrance (Parfum), Methylparaben, Propylparaben, Green 3 (CI 42053), Red 33 (CI 17200)

🎯 Purpose 2 words ▾

Purpose Antimicrobial

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 21749-0501-80 · GOJO 21749-0523-20 · GOJO →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.