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GOJO Gold and Klean Antimicrobial Ltn Sp Chloroxylenol .003 mg/mL Liquid, 800 mL — NDC 21749-0501-80 package photo

GOJO Gold and Klean Antimicrobial Ltn Sp Chloroxylenol .003 mg/mL Liquid, 800 mL

by GOJO Industries, Inc. · 800 mL in 1 PACKAGE (21749-501-80)
NDC 21749-0501-80
🏷️ FDA NDC (as labeled) 21749-501-80 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 21749-501-80
Product NDC 21749-501
11-digit billing NDC 21749050180
UNII 0F32U78V2Q
Application # 505G(a)(3)
SPL Set ID 3420d7bd-97d7-4b61-9cee-db2bbafc99e3
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2003-07-13
Route TOPICAL
Dosage form LIQUID
Substance CHLOROXYLENOL
Why two NDCs? The FDA registers this code as 21749-501-80 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 21749-0501-80. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerGOJO Industries, Inc.
FDA application505G(a)(3) (OTC MONOGRAPH DRUG)
Labeler code21749
First marketedJul 2003
Product typeHuman Otc Drug
Portfolio79 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

GOJO Gold and Klean Antimicrobial Lotion is a topical liquid cleanser containing chloroxylenol, an antimicrobial agent. This over-the-counter product is marketed under FDA's monograph rules for antimicrobial skin cleansers. Chloroxylenol is typically used in skin-cleaning products to help reduce bacteria and germs on the hands and body. The lotion form allows for easy application and rinsing.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 9E8X80D2L0
    A synthetic form of vitamin E used as an antioxidant and preservative in medications. It helps prevent the active ingredients from degrading when exposed to oxygen or light.
  • UNII C80684146D
    A foaming agent and thickener derived from coconut oil. It helps create a smooth texture and stable foam in liquid or semi-solid medicines, improving how the product feels and applies.
  • UNII 03DH2IZ3FY
    A mild cleansing agent derived from coconut oil. It's used in medicines as a surfactant to help dissolve or distribute other ingredients evenly throughout the formulation.
  • UNII 40U37V505D
    A fatty acid derived from coconut oil. It acts as an emulsifier to help mix water and oil-based ingredients, and may also serve as a surfactant or lubricant in tablet and capsule formulations.
  • UNII 8470G57WFM
    Corn oil is a vegetable oil extracted from corn kernels. It's used in medicines as a solvent to dissolve active ingredients and help the body absorb them, and sometimes as a lubricant in capsules.
  • UNII MP1J8420LU
    A salt derived from edetic acid that binds to trace metals in medicines. It serves as a chelating agent and preservative to prevent metal-catalyzed breakdown of the drug and extend shelf life.
  • UNII 5KV86114PT
    A chemical compound used in medicines as a pH buffer and neutralizing agent. It helps maintain the proper acidity level in liquid formulations to improve stability and make the medicine easier to take.
  • UNII 2UMI9U37CP
    Oleic acid is a naturally occurring fatty acid derived from plant or animal oils. It functions as an emulsifier and solvent in medicines, helping blend water and oil-based ingredients together and dissolving other components.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII 0YPR65R21J
    Sodium sulfate is a mineral salt used in pharmaceuticals as a filler and diluent. It helps provide bulk and stability to tablets and capsules while remaining inert in the body.
  • UNII 1D1K0N0VVC
    A fat-soluble form of vitamin A used as a colorant and nutritional fortification ingredient. It gives products a yellow or orange tint and increases vitamin A content in the formula.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

12 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesWater (Aqua), Coconut Acid, Oleic Acid, Sodium Sulfate, Ethanolamine, Cocamide MEA, Coco-Betaine, Propylene Glycol, Retinyl Palmitate, Tetrasodium EDTA, Tocopheryl Acetate, Zea Mays (Corn) Oil, Fragrance (Parfum)

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Luxury Foam Antibacterial .003 mg/mL 21749-0080-42 GOJO 1250 ml — — FDA listed —
GOJO PCMX E-2 Sanitizing Ltn Sp .003 mg/mL 21749-0457-20 GOJO 2000 ml — — FDA listed —
Antimicrobial Hand So ap .003 mg/mL 61666-0003-42 Waxie 1250 ml — — Discontinued —
PRO-LINK Free Hands Antibacterial Foam So ap .003 mg/mL 66908-0081-40 Pro-Link, 1200 ml — — FDA listed —
GOJO Gold and Klean Antimicrobial Ltn Sp .003 mg/mLthis 21749-0501-80 GOJO 800 ml — — FDA listed —
BRIGHTON PROFESSIONAL Antibacterial Foaming Hand So ap .003 mg/mL 49514-0080-42 Staples 1250 ml — — FDA listed —
BRIGHT SOLUTIONS Antimicrobial Foam So ap .003 mg/mL 66885-0081-40 Kel-San, 1200 ml — — FDA listed —
EXTENDED CARE Foaming Antimicrobial Handwash .003 mg/mL 71875-0080-42 TRIPLE 1250 ml — — FDA listed —
RENOWN Antibacterial Foam Cleanser .003 mg/mL 71896-0081-42 Interline 1250 ml — — FDA listed —
QSC Foam Fresh Antimicrobial Hand .003 mg/mL 59110-0081-42 Triple 1250 ml — — FDA listed —
WAXIECARE Pink Antibacterial Ltion So ap .003 mg/mL 61666-0004-67 Waxie 2000 ml — — FDA listed —
DON Luxury Foam Antibacterial Handwash .003 mg/mL 66910-0600-42 Edward 1250 ml — — FDA listed —
Premium Foam Antibacterial .003 mg/mL 21749-0085-23 GOJO 222 ml — — FDA listed —
PRIMORY Antimicrobial Foam .003 mg/mL 21749-0555-43 GOJO 1500 ml — — Discontinued —
MICRELL Antibacterial Ltn Sp .003 mg/mL 21749-0975-04 GOJO 118 ml — — Discontinued —
GRAND TOUCH Antimicrobial Ltion So ap .003 mg/mL 61666-0007-34 Waxie 1000 ml — — FDA listed —
GENUINE JOE Cleaning Supplies Antibacterial Foam So ap Refill .003 mg/mL 62832-0080-42 S.P. 1250 ml — — FDA listed —
PROVON Foaming Antimicrobial Handwash with Moisturizers .003 mg/mL 21749-0090-22 GOJO 200 ml — — Discontinued —
ACQUAINT Antibacterial Foam Handwash .003 mg/mL 21749-0551-90 GOJO 1250 ml — — FDA listed —
TOUGH GUY Antibacterial Foam Hand So ap .003 mg/mL 40096-0081-01 W.W. 1200 ml — — FDA listed —
GOJO Antibacterial Ltn Sp .003 mg/mL 21749-0458-37 GOJO 3780 ml — — FDA listed —
PROVON Antimicrobial Ltn Sp with 0.3% PCMX .003 mg/mL 21749-0750-04 GOJO 118 ml — — FDA listed —
Southern Soft Luxury Foam Antibacterial Hand Wash .003 mg/mL 53341-0080-42 CCP 1250 ml — — FDA listed —
Antimicrobial Foam So ap with PCMX .003 mg/mL 61666-0005-40 Waxie 1200 ml — — FDA listed —
PRIME SOURCE Antimicrobial Foam So ap .003 mg/mL 66294-0082-40 BUNZL 1200 ml — — FDA listed —
Reliable Luxury Foam Antimicrobial Handwash Fresh Fruit Scent .003 mg/mL 71897-0080-40 Veritiv 1200 ml — — FDA listed —
EXCELON Antimicrobial Foam .003 mg/mL 21749-0580-43 GOJO 1500 ml — — Discontinued —
SIGNATRY Antimicrobial Foam .003 mg/mL 21749-0581-43 GOJO 1500 ml — — Discontinued —
TOUGH GUY 821 Antimicrobial Liquid Ltion So ap .003 mg/mL 40096-0051-01 W.W. 3780 ml — — FDA listed —
TOUGH GUY Antimicrobial Foam So ap .003 mg/mL 40096-0080-05 W.W. 1250 ml — — FDA listed —
AFFEX Foaming Antimicrobial Hand So ap .003 mg/mL 54057-0083-42 Afflink, 1250 ml — — FDA listed —
BRIGHT SOLUTIONS Foaming Antimicrobial So ap .003 mg/mL 66885-0080-42 Kel-San, 1250 ml — — FDA listed —
RENOWN Antimicrobial So ap .003 mg/mL 71896-0051-27 Interline 800 ml — — Discontinued —
BRIGHTON PROFESSIONAL Premium Antibacterial Foam So ap .003 mg/mL 49514-0081-40 Staples 1200 ml — — FDA listed —
BOARDWALK Antibacterial Foam Handwash .003 mg/mL 71906-0080-42 Essendant 1250 ml — — FDA listed —
QSC TF Ambre Antibacterial Wash .003 mg/mL 59110-0082-40 Triple 1200 ml — — FDA listed —
GOJO RICH PINK Antibacterial Ltn Sp .003 mg/mL 21749-0060-20 GOJO 2000 ml — — FDA listed —
GOJO Ultra Mild Antimicrobial Ltn Sp with Chloroxylenol .003 mg/mL 21749-0211-10 GOJO 1000 ml — — Discontinued —
COMPANIONS Luxury Foam Hand So ap, Antimicrobial .003 mg/mL 24205-0080-42 UniPro 1250 ml — — FDA listed —
ARRAY Anitbacterial Foam Handwash .003 mg/mL 52220-0080-40 Gordon 1200 ml — — Discontinued —
AFFEX Antimicrobial Foaming Hand So ap .003 mg/mL 54057-0082-42 Afflink, 1250 ml — — FDA listed —
PRIME SOURCE Antimicrobial Foaming Hand So ap .003 mg/mL 66294-0080-42 BUNZL 1250 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2003
On the market since
Jul 2003
📍
2026
Currently FDA-listed
23 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for GOJO Gold and Klean Antimicrobial Ltn Sp (this brand).

Top reported reactions

Vomiting2
Abdominal Pain Lower1
Abdominal Pain Upper1
Anaemia1
Cholecystitis1
Cystitis1
Drug Effect Decreased1

Age at onset

Elderly1

Reporter sex

7 reports
Male · 14%
Female · 86%

Serious outcomes

Hospitalization3
Life-threatening1
Death1
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
21749-0501-80 You're viewing this 800 mL in 1 PACKAGE (21749-501-80) 2003-07-13 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 21749-501-80, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 21749-0501-80, written without dashes as 21749050180. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 21749-0501-80, the first segment (21749) is the labeler code FDA assigned to GOJO Industries, Inc.; the middle segment (0501) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (80) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by GOJO Industries, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
GOJO Industries, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 15 words ▾

Use • Handwash to help decrease bacteria on the skin • Recommended for repeated use

⏱️ Dosage and Administration 23 words ▾

Directions • Wet hands • Apply a small amount of product and work into a lather • Rinse well and dry hands completely

⚠️ Warnings 58 words ▾

Warnings For external use only When using this product do not use in or near the eyes. In case of contact, rinse eyes thoroughly with water. Stop use and ask a doctor if irritation or rash appears and lasts Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 4 words ▾

Active ingredient Chloroxylenol 0.3%

🧪 Inactive Ingredients 28 words ▾

Inactive ingredients Water (Aqua), Coconut Acid, Oleic Acid, Sodium Sulfate, Ethanolamine, Cocamide MEA, Coco-Betaine, Propylene Glycol, Retinyl Palmitate, Tetrasodium EDTA, Tocopheryl Acetate, Zea Mays (Corn) Oil, Fragrance (Parfum)

🎯 Purpose 2 words ▾

Purpose Antimicrobial

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 21749-0461-89 · GOJO 21749-0521-53 · GOJO →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.