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First Degree Calendula Officinalis, Echinacea Angustifolia, Cantharis Vesicatoria 1 [hp_Q]/.1g; 1 [hp_Q]/.1g; 3 [hp_X]/.1g Tincture — NDC 24330-110-21 (Billing 24330-0110-21)

by Welmedix LLC · 1 TUBE in 1 CARTON / 21 g in 1 TUBE

This is a package of First Degree Calendula Officinalis, Echinacea Angustifolia, Cantharis Vesicatoria 1 [hp_Q]/.1g; 1 [hp_Q]/.1g; 3 [hp_X]/.1g Tincture from Welmedix LLC, marketed since Jan 2007 and currently FDA-listed.

NDC 24330-0110-21
🏷️ FDA NDC (as labeled) 24330-110-21 billing pads the product segment with a zero
This package
Contains21 g in 1 tube Pack sizes3 compare ↓
Product page 24330-0110-14 Also comes in: 14 g 24330-110-14 21 g 24330-110-22
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 24330-110-21 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
24330 labeler · 110 product · 21 package
Package marketed since
Jan 1, 2007
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 2433011021 6
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 24330-110-21
Product NDC 24330-110
11-digit billing NDC 24330011021
UNII 18E7415PXQ, VB06AV5US8, 3Q034RO3BT
SPL Set ID e10bcfb8-079f-4033-a805-35d03c7ebd64
DEA schedule Non-controlled
Marketing category UNAPPROVED HOMEOPATHIC
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2007-01-01
Route TOPICAL
Dosage form TINCTURE
Substance CALENDULA OFFICINALIS FLOWERING TOP; ECHINACEA ANGUSTIFOLIA; LYTTA VESICATORIA
Why two NDCs? The FDA registers this code as 24330-110-21 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 24330-0110-21. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

This is an unapproved homeopathic tincture applied to the skin containing calendula officinalis, echinacea angustifolia, and lytta vesicatoria. In homeopathic tradition, these plant-derived ingredients are used to address minor skin irritation and promote skin healing. Homeopathic products are marketed based on historical use and homeopathic theory rather than FDA evaluation for safety or effectiveness. The potencies listed indicate this product has been prepared according to homeopathic dilution methods.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 14 g 21 g
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
24330-0110-14 24330-110-14 Main listing 1 TUBE in 1 CARTON / 14 g in 1 TUBE 2014-05-01 — Active
24330-0110-21 You're viewing this 1 TUBE in 1 CARTON / 21 g in 1 TUBE 2007-01-01 — Active
24330-0110-22 24330-110-22 1 TUBE in 1 CARTON / 21 g in 1 TUBE 2015-03-01 — Active

Pack size FAQ

What quantity is in this package?
This package is listed by the FDA — 1 tube in 1 carton / 21 g in 1 tube.
What NDC number is used to bill for this package of First Degree Calendula Officinalis, Echinacea Angustifolia, Cantharis Vesicatoria 1 [hp_Q]/.1g; 1 [hp_Q]/.1g; 3 [hp_X]/.1g Tincture?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
First Degree 1 [hp_Q]/.1g; 1 [hp_Q]/.1g; 3 [hp_X]/.1gthis 24330-0110-21 Welmedix 1 tube — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2007
On the market since
Jan 2007
📍
2026
Currently FDA-listed
19 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII U333RI6EB7
    Hydrogenated polydecene type I is a synthetic oil derived from plant-based polymers. It acts as a lubricant and glidant to help powder ingredients flow smoothly during tablet or capsule manufacturing.
  • UNII 0RE8K4LNJS
    Isopropyl myristate is an oily liquid made from coconut or palm oil. It's used in medicines as an emollient and penetration enhancer to help the medicine absorb through skin or improve spreadability in topical products.
  • UNII 7EV65EAW6H
    Lanolin is a waxy substance derived from sheep's wool. It's used in medicines as an emollient and skin-conditioning agent to soften formulations and improve spreadability in topical products like creams and ointments.
  • UNII A2I8C7HI9T
    Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
  • UNII Z8IX2SC1OH
    Propylparaben is a chemical preservative used to prevent bacterial and fungal growth in medicines and personal care products. It helps extend shelf life and maintain product safety during storage.
  • UNII K49155WL9Y
    Shea butter is a fat extracted from shea tree nuts. It's used in medicines as an emollient and lubricant to soften the product, improve texture, and help ingredients blend smoothly together.
  • UNII G624N6MSBA
    A synthetic surfactant derived from coconut oil. It helps dissolve and distribute other ingredients evenly throughout the medicine, acting as an emulsifier and solubilizer in liquid formulations.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesbutyrospermum parkii (shea butter), C18-22 hydroxyalkyl hydroxypropyl guar, hydrogenated polydecene, isopropyl myristate, lanolin, methylparaben, propylparaben, purified water, sodium polyacryloyldimethyl taurate, trideceth-10

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerWelmedix LLC
Labeler code24330
First marketedJan 2007
Product typeHuman Otc Drug
Portfolio8 products on file

More NDCs from Welmedix LLC labeler code 24330

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 45 words ▾

Uses Temporarily relieves symptoms such as minor skin pain, rawness and itching due to: • minor burns • insect bites • minor scrapes • scalds Product Uses are based on the Homeopathic Materia Medica, and have not been evaluated by the Food and Drug Administration.

⏱️ Dosage and Administration 46 words ▾

Directions • for best results, apply immediately to affected area • adults and children 2 years of age and older: apply to affected area 2-3 times a day, as needed, or as directed by your doctor • children under 2 years of age: consult a doctor

⚠️ Warnings 5 words ▾

Warnings For external use only

🧪 Active Ingredient 43 words ▾

Active ingredients Calendula officinalis TINC HPUS Cantharis vesicatoria 3X HPUS Echinacea angustifolia TINC HPUS The letters ‘HPUS’ indicate that the active ingredients are officially monographed in the Homeopathic Pharmacopoeia of the United States. TINC and 3X are homeopathic dilutions: see www.firstdegree.com for details.

🧪 Inactive Ingredients 23 words ▾

Inactive ingredients butyrospermum parkii (shea butter), C18-22 hydroxyalkyl hydroxypropyl guar, hydrogenated polydecene, isopropyl myristate, lanolin, methylparaben, propylparaben, purified water, sodium polyacryloyldimethyl taurate, trideceth-10

🎯 Purpose 18 words ▾

Purposes wound healing, superficial burns and scalds burns, scalds, rawness, burning pain itching, burning, irritation from insect bites

📄 Do Not Use 49 words ▾

Do not use • if you have an allergy or hypersensitivity to any ingredients or if you have had a prior reaction to this product • over large areas of the body • on deep or puncture wounds • on animal bites • on serious burns, cuts or scrapes

📄 When Using This Product 9 words ▾

When using this product do not get into eyes

📄 Stop Use and Ask a Doctor If 27 words ▾

Stop use and ask a doctor if • condition worsens • symptoms last more than 7 days or clear up and occur again within a few days

🤰 If Pregnant or Breast-Feeding 11 words ▾

If pregnant or breast feeding ask a health professional before use.

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Questions or Comments 9 words ▾

Questions or comments? Call 1-888-565-2876 Monday through Friday, 9am-5pm

📄 Package Label / Principal Display Panel 177 words ▾

Principal Display Panel - First°Degree ® Therapeutic Burn Cream NEW THERAPEUTIC BURN CREAM First°Degree® NDC 24330-0110-21 • Soothes the pain & cools the burn • Acts as an antiseptic for burns • Helps reduce the appearance of scars Homeopathic Burns Happen. Be Prepared.™ NET WT. 3/4 OZ (21g) Carton Label - First°Degree ® Therapeutic Burn Cream Carton Label - First Degree Therapeutic Burn Cream

Principal Display Panel - First°Degree ® Burn Cream BURN CREAM First°Degree ® • Helps reduce the appearance of scars • Protects against infection • Soothes the pain & cools the burn NET WT 1/2 oz (14 g) 1 TUBE Homeopathic Carton Label - First°Degree ® Burn Cream Carton Label - First Degree Burn Cream

Principal Display Panel – First°Degree ® Multi-Symptom Burn Cream INSTANTLY SOOTHING! 96% NATURAL First°Degree ® MULTI-SYMPTOM BURN CREAM SOOTHES THE PAIN & COOLS THE BURN HELPS HEAL MINOR BURNS HELPS REDUCE THE APPEARANCE OF SCARS Net Wt 3/4 oz (21g) 1 TUBE HOMEOPATHIC Carton Label - First°Degree ® Multi-Symptom Burn Cream Carton Label - First Degree Multi-Symptom Burn Cream

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product Homeopathic listing

About homeopathic listings

First Degree Calendula Officinalis, Echinacea Angustifolia, Cantharis Vesicatoria 1 [hp_Q]/.1g; 1 [hp_Q]/.1g; 3 [hp_X]/.1g TINCTURE is listed under the homeopathic marketing category. An NDC listing in this category does not by itself establish FDA approval, and FDA does not evaluate homeopathic products for effectiveness. This page reports the listing data as published.

What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Homeopathic". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Welmedix LLC. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 1 tube (24330-0110-14), 1 tube (24330-0110-22). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Welmedix LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 24312-0003-01 · Airtec 24330-0130-02 · Welmedix →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.