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GNP Regular Strength Gas Relief DIMETHICONE 80 mg Tablet, Chewable, 100-count — NDC 24385-118-78 (Billing 24385-0118-78)

by Amerisource Bergen · 100 TABLET, CHEWABLE in 1 BOTTLE

This is a package of 100 tablets of GNP Regular Strength Gas Relief DIMETHICONE 80 mg Tablet, Chewable from Amerisource Bergen, marketed since Aug 2011 and currently FDA-listed; retail pharmacies pay about $0.0322 per tablet (NADAC). It is this product's only package size.

NDC 24385-0118-78
🏷️ FDA NDC (as labeled) 24385-118-78 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Other active recalls for Dimethicone (different manufacturers) — 1 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · Jun 11, 2026 — Failed Impurities/Degradation Specifications; Formaldehyde levels exceeded specification. (BioMed Laboratories, LLC.) · FDA recall D-0663-2026
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 24385-118-78
Product NDC 24385-118
11-digit billing NDC 24385011878
NCPDP billing unit EA — each (per item)
RxCUI 314216
UNII 92RU3N3Y1O
Application # M002
SPL Set ID 7b63b265-e4f2-4103-935c-22d2d89cc5e8
Physiologic effect Skin Barrier Activity
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2011-08-08
Route ORAL
Dosage form TABLET, CHEWABLE
Substance DIMETHICONE

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GPI-14 52200020000510
GPI class GNP Gas Relief
GCN Seq No 002821
GCN 08281
HICL code 001224
Ingredient (HICL) Simethicone
HIC1 code D
Therapeutic class — broad (HIC1) Biliary System/Gastro-Intestinal System
HIC2 code D4
Therapeutic class — intermediate (HIC2) Drugs Acting Principally On The Alimentary Tract
HIC3 code D4N
Therapeutic class — specific (HIC3) Antiflatulents
AHFS code 56:10.00.00
AHFS class Antiflatulents
FDB label name GNP GAS RLF(SIMETH) 80 MG CHEW
FDB brand name Gas Relief
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 002821
  • GCN: 08281
  • GPI-14 (Medi-Span): 52200020000510
  • HICL (First Databank): 001224
  • AHFS class code: 56:10.00.00
  • RxCUI (RxNorm): 314216
Why two NDCs? The FDA registers this code as 24385-118-78 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 24385-0118-78. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

Label name GNP GAS RLF(SIMETH) 80 MG CHEW Ingredient Simethicone
📗 Our plain-language guide HelloPharmacist
  • It relieves the discomfort of gas. For adults, that means pressure, bloating and fullness. Infant drops are for baby gas, often caused by swallowed air or certain formulas or foods...
  • Shake the bottle well. Use only the syringe or dropper that came with it. Dispense it slowly toward the inner cheek. You can also mix it with 1 oz. of cool water, formula or anothe...
  • Doses can be repeated as needed after meals and at bedtime. Do not go over 12 doses in a day. Follow your product’s label and your doctor’s advice.
  • If you can, use your child’s weight. If not, use age. Check the chart on your product, and ask me or your doctor if you are unsure.
📖 Read our full Simethicone guide →

Supplement & herbal interactions

Some supplements/herbs that may interact with Dimethicone — tap one for details:

Dimethylsulfoxide (dmso)Moderate Turpentine OilModerate AlchemillaMinor
🌿 Every supplement checked against Dimethicone (3 interactions) — ranked by severity →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.032 $3.22 / 100 tablets
Medicaid paysCMS SDUD · 12 mo $0.1411 $14.11 / 100 tablets
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Jan 2022 Aug 2022 Jan 2026 Sep 2026 $0.037 $0.027
▲ Up 12% over the last 24 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
24385-0118-78 You're viewing this Main listing 100 TABLET, CHEWABLE in 1 BOTTLE 2011-08-08 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Antiflatulent 80 mg 00904-7206-60 Major 100 tablets $0.032 — Availability likely —
GNP Regular Strength Gas Relief 80 mgthis 24385-0118-78 Amerisource 100 tablets $0.032 — Availability likely —
Leader Gas relief 80 mg 70000-0434-01 CARDINAL 100 tablets $0.032 — Availability likely —
Gas Relief 80 mg 70677-1067-01 STRATEGIC 36 tablets $0.032 — Availability likely —
Gas Relief 80 mg 17714-0019-01 Advance 100 tablets — — FDA listed —
GNP Regular Strength Gas Relief 80 mg 17856-1118-01 ATLANTIC 1 tablet — — FDA listed —
CVS PHARMACY Gas relief 80 mg 51316-0111-00 CVS 100 tablets — — FDA listed —
Gas relief Anti-gas 80 mg 51316-0904-16 CVS 100 tablets — — FDA listed —
Gas relief 80 mg 53041-0103-16 Guardian 100 tablets — — FDA listed —
Gas relief 80 mg 53943-0301-16 Discount 100 tablets — — FDA listed —
Simethicone 80 mg 54738-0518-01 Richmond 100 tablets — — FDA listed —
Simethicone 80Mg 80 mg 55154-2606-00 Cardinal 1 tablet — — FDA listed —
Simethicone 80 mg 57896-0791-01 Geri-Care 100 tablets — — FDA listed —
QC Gas Relief Mint Flavor 80 mg 63868-0108-01 QUALITY 100 tablets — — FDA listed —
Simethicone 80 mg 68071-2746-03 NuCare 30 tablets — — FDA listed —
Gas Relief Mint Flavor 80 mg 68163-0111-36 Raritan 36 tablets — — FDA listed —
Simethicone 80 mg 69618-0033-01 Reliable 100 tablets — — FDA listed —
Simethicone 80 mg 71610-0607-04 Aphena 4 tablets — — FDA listed —
Simethicone 80 mg 71610-0649-04 Aphena 4 tablets — — FDA listed —
Antiflatulent 80 mg 71610-0650-04 Aphena 4 tablets — — FDA listed —
Simethicone 80Mg 80 mg 77333-0812-10 Gendose 1 tablet — — FDA listed —
Simethicone 80 mg 82804-0043-30 Proficient 30 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2011
On the market since
Aug 2011
📍
2026
Currently FDA-listed
15 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerAmerisource Bergen
FDA applicationM002 (OTC MONOGRAPH DRUG)
Labeler code24385
First marketedAug 2011
Product typeHuman Otc Drug
Portfolio206 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 9 words ▾

Uses relieves: pressure bloating symptoms referred to as gas

⏱️ Dosage and Administration 26 words ▾

Directions chew 2 to 4 tablets thoroughly as needed after meals and at bedtime. do not exceed 6 tablets per day unless directed by a physician.

⚠️ Warnings 21 words ▾

Warnings Keep out of reach of children. In case of overdose, get medical help or contact a poison control center immediately.

📦 Storage and Handling 27 words ▾

Other information do not use if inner seal is broken. store at room temperature avoid high humidity and excessive heat, above 40 0 C (104 0 F)

🧪 Active Ingredient 8 words ▾

Active ingredient (in each tablet) Simethicone 80 mg

🧪 Inactive Ingredients 12 words ▾

Inactive ingredients compressible sugar, dextrose, flavor, magnesium stearate, maltodextrin, microcrystalline cellulose, sorbitol

🎯 Purpose 2 words ▾

Purpose Antigas

📄 Package Label / Principal Display Panel 34 words ▾

PDP NDC 24385-118-78 Good Neighbor Pharmacy Compare to Mylanta Gas active ingredient regular strength Gas Relief Anti-gas fast relief of: pressure, bloating & gas distress mint 100 chewable tablets (80 mg ea.) image description

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for this package alone, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
13.3K
Units reimbursed last 4 qtrs
714.7K
Gross reimbursed last 4 qtrs
$100.8K
Avg / prescription
$7.61
Avg / unit
$0.1411
Latest quarter Q1 2026
1.4KRx
Medicaid pays / ea
$0.1411
gross reimbursed
vs
NADAC / ea
$0.0322
acquisition cost
=
Spread
+$0.1089
+338% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
63% FFS 37% MCO
Fee-for-service · 8,309 Rx Managed care · 4,951 Rx
State Medicaid map
Alaska: no data reported AK Maine: 9,510 units · 682 per 100k residents ME Washington: 26,054 units · 334 per 100k residents WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: 30,970 units · 540 per 100k residents MN Wisconsin: no data reported WI Michigan: 33,774 units · 336 per 100k residents MI New York: 4,584 units · 23.4 per 100k residents NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: 44,372 units · 1,048 per 100k residents OR Nevada: no data reported NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: 11,315 units · 90.2 per 100k residents IL Indiana: no data reported IN Ohio: 28,216 units · 239 per 100k residents OH Pennsylvania: 47,120 units · 364 per 100k residents PA New Jersey: 33,960 units · 366 per 100k residents NJ Massachusetts: 34,454 units · 492 per 100k residents MA California: 305,518 units · 784 per 100k residents CA Utah: no data reported UT Colorado: no data reported CO Nebraska: 8,865 units · 448 per 100k residents NE Missouri: no data reported MO Kentucky: 35,785 units · 791 per 100k residents KY West Virginia: no data reported WV Virginia: 9,834 units · 113 per 100k residents VA Maryland: no data reported MD Connecticut: no data reported CT Rhode Island: 2,753 units · 251 per 100k residents RI Arizona: 2,900 units · 39.0 per 100k residents AZ New Mexico: no data reported NM Kansas: no data reported KS Arkansas: no data reported AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: 31,145 units · 282 per 100k residents GA D.C.: no data reported DC Hawaii: 13,561 units · 945 per 100k residents HI Texas: no data reported TX Florida: no data reported FL
Units reimbursed · per 100k residents
23.41,048
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Oregon 1,048 /100k
2 Hawaii 945 /100k
3 Kentucky 791 /100k
4 California 784 /100k
5 Maine 682 /100k
6 Minnesota 540 /100k
7 Massachusetts 492 /100k
8 Nebraska 448 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for GNP Regular Strength Gas Relief (this brand).

Top reported reactions

Vomiting56
Diarrhoea52
Abdominal Pain49
Pyrexia48
Nausea47
Pneumonia41
Decreased Appetite35

Age at onset

Child5
Adolescent5
Adult59
Elderly63

Reporter sex

676 reports
Male · 49%
Female · 51%
Unknown · 0%

Serious outcomes

Death131
Life-threatening60
Disabling14
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 88 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
← 24385-0110-09 · AmerisourceBergen 24385-0121-01 · AMERISOURCE →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.