Nighttime Relief Lubricant Light Mineral Oil, White Petrolatum 425 mg/g; 573 mg/g Ointment, 1 tube
by Amerisource Bergen Drug Corp. · 1 TUBE in 1 BOX (46122-757-37) / 3.5 g in 1 TUBE
NDC 46122-0757-37
🏷️ FDA NDC (as labeled)
46122-757-37
billing pads the product segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
46122-757-37
Product NDC
46122-757
11-digit billing NDC
46122075737
NCPDP billing unit
GM — per gram (weight)
RxCUI
702008
UNII
N6K5787QVP, B6E5W8RQJ4
UPC
0346122757379
Application #
M018
SPL Set ID
fd6b2be8-7e00-3765-e053-6294a90a4061
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2023-06-05
Route
OPHTHALMIC
Dosage form
OINTMENT
Substance
LIGHT MINERAL OIL; WHITE PETROLATUM
GPI-14
86209902904220
GCN Seq No
065933
GCN
28068
HICL code
002215
Ingredient (HICL)
Mineral Oil/Petrolatum,White
HIC1 code
Q
Therapeutic class — broad (HIC1)
Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code
Q6
Therapeutic class — intermediate (HIC2)
Ophthalmic Preparations
HIC3 code
Q6Y
Therapeutic class — specific (HIC3)
Eye Preparations, Miscellaneous (Otc)
AHFS code
52:92.00.00
AHFS class
Eent Drugs, Miscellaneous
FDB label name
NIGHTTIME LUBRICANT EYE OINT
FDB brand name
Nighttime Relief Lubricant Eye
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 46122-757-37 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 46122-0757-37. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Softeners, emollients class.
Drug family (ATC)
Softeners, emollients
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerAmerisource Bergen Drug Corp.
FDA applicationM018 (OTC MONOGRAPH DRUG)
Labeler code46122
First marketedJun 2023
Product typeHuman Otc Drug
Portfolio3 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name NIGHTTIME LUBRICANT EYE OINT Ingredient Mineral Oil/Petrolatum,White
🧪 What is this product?
Nighttime Relief Lubricant Light Mineral Oil, White Petrolatum is an over-the-counter ophthalmic ointment marketed under FDA's OTC monograph rules. It contains light mineral oil and white petrolatum, which are lubricating agents typically used to soothe and protect the eye surface. This type of product is commonly applied to the eye area to help relieve dryness and provide a protective coating, especially at nighttime when tear production may be lower.
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Light Mineral Oil, White Petrolatum?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII 884C3FA9HE
Lanolin alcohol is a waxy substance derived from sheep's wool. It functions as an emollient and emulsifier in medicines, helping blend oil and water-based ingredients while softening the product's texture.
1 inactive ingredient listed in the exact product block matched to this NDC.
The official label also stateslanolin alcohols
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $1.488 | $5.21 / 3.5 g |
| Medicaid paysCMS SDUD · 12 mo | $3.93 | $13.76 / 3.5 g |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per g) — tap or hover for the price & month
▼ Down 14% over the last 10 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Nighttime Relief Lubricant 425 mg/g; 573 mg/gthis 46122-0757-37 | Amerisource | 1 tube | $1.488 | — | Availability likely | — |
| Leader Nighttime Relief Lubricant Eye 425 mg/g; 573 mg/g 70000-0724-01 | LEADER/Cardinal | 1 tube | $1.488 | — | Availability likely | — |
| Refresh P.m. 425 mg/g; 573 mg/g 00023-0667-04 | Allergan, | 1 tube | $2.449 | — | Availability likely | +65% |
| Equate Nighttime Relief Lubricant 425 mg/g; 573 mg/g 11716-0367-01 | Hanlim | 1 tube | — | — | FDA listed | — |
| Lubricant Eye PM 42.5 g/100g; 57.3 g/100g 69618-0060-76 | Reliable | 1 tube | — | — | FDA listed | — |
| Equate Nighttime Relief Lubricant 425 mg/g; 573 mg/g 79903-0260-35 | Walmart | 1 tube | — | — | FDA listed | — |
| Equate Nighttime Relief Lubricant 425 mg/g; 573 mg/g 79903-0367-01 | Walmart | 1 tube | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2023
On the market since
Jun 2023
📍
2026
Currently FDA-listed
3 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🗺️ Medicaid utilization & spend
📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 46122-0757-37, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
10K
Units reimbursed last 4 qtrs
37.1K
Gross reimbursed last 4 qtrs
$145.8K
Avg / prescription
$14.61
Avg / unit
$3.9323
Latest quarter Q1 2026
2.8KRx
Medicaid pays / g
$3.9323
gross reimbursed
vs
NADAC / g
$1.4881
acquisition cost
=
Spread
+$2.4442
+164% vs cost
What Medicaid paid per g (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
Fee-for-service · 9,544 Rx Managed care · 434 Rx
State Medicaid map
Units reimbursed · per 100k residents
1.8170
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
Prescriptions—
Units—
Reimbursed—
🏆 Top states by units · per 100k residents
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 46122-0757-37 You're viewing this | 1 TUBE in 1 BOX (46122-757-37) / 3.5 g in 1 TUBE | 2023-06-05 | Active |
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses for temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun may be used as a protectant against further irritation
⏱️ Dosage and Administration ▾
Directions pull down the lower lid of the affected eye apply a small amount (1/4 inch) of ointment to the inside of eyelid
⚠️ Warnings ▾
Warnings For external use only Do not use except under the advice and supervision of a doctor When using this product replace cap after use to avoid contamination do not touch tip of container to any surface remove contact lenses before using Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye condition worsens or persists for more than 72 hours Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.
🧪 Active Ingredient ▾
Active ingredients Light Mineral Oil 42.5% White Petrolatum 57.3%
🧪 Inactive Ingredients ▾
Inactive ingredient lanolin alcohols
🎯 Purpose ▾
Purposes Eye Lubricant Eye Lubricant
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.