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Good Neighbor Pharmacy Eye Drops Multi-Symptom Relief Polyethylene glycol 400, Tetrahydrozoline HCl, Zinc sulfate 400 1 g/100mL; .05 g/100mL; .25 g/100mL Solution/ Drops — NDC 46122-758-29 (Billing 46122-0758-29)

by Amerisource Bergen Drug Corp. · 1 BOTTLE, DROPPER in 1 BOX / 15 mL in 1 BOTTLE, DROPPER

This is a package of Good Neighbor Pharmacy Eye Drops Multi-Symptom Relief Polyethylene glycol 400, Tetrahydrozoline HCl, Zinc sulfate 400 1 g/100mL; .05 g/100mL; .25 g/100mL Solution/ Drops from Amerisource Bergen Drug Corp., no longer marketed (first marketed Jun 2023), no longer in the FDA NDC Directory; retail pharmacies pay about $0.1968 per mL (NADAC). It is this product's only package size.

NDC 46122-0758-29
🏷️ FDA NDC (as labeled) 46122-758-29 billing pads the product segment with a zero
OTC Discontinued Non-controlled ⚠ Discontinued by firm ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 16, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 46122-758-29 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
46122 labeler · 758 product · 29 package
Package marketed since
Jun 5, 2023
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC)
0346122758291
FDA record last changed
Jul 16, 2026
⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. The listing was last certified through Jul 2026. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 46122-758-29
Product NDC 46122-758
11-digit billing NDC 46122075829
NCPDP billing unit ML — per mL (volume)
RxCUI 2360903
UNII B697894SGQ, 0YZT43HS7D, 89DS0H96TB
UPC 0346122758291
Application # M018
SPL Set ID fd684602-6583-2cb8-e053-6294a90a7af0
Established class (EPC) Copper Absorption Inhibitor
Physiologic effect Decreased Copper Ion Absorption
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Discontinued by firm (certified through Jul 2026)
Marketing start 2023-06-05
Route OPHTHALMIC
Dosage form SOLUTION/ DROPS
Substance POLYETHYLENE GLYCOL 400; TETRAHYDROZOLINE HYDROCHLORIDE; ZINC SULFATE

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GCN Seq No 085370
GCN 54831
HICL code 049245
Ingredient (HICL) Tetrahydrozoline/Zinc/Peg 400
HIC1 code Q
Therapeutic class — broad (HIC1) Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code Q6
Therapeutic class — intermediate (HIC2) Ophthalmic Preparations
HIC3 code Q6D
Therapeutic class — specific (HIC3) Eye Vasoconstrictors (Otc Only)
AHFS code 52:32.00.00
AHFS class Vasoconstrictors
FDB label name GNP MULTI-SYMPTOM RLF EYE DROP
FDB brand name Multi-Symptom Relief Eye
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 085370
  • GCN: 54831
  • HICL (First Databank): 049245
  • AHFS class code: 52:32.00.00
  • RxCUI (RxNorm): 2360903
Why two NDCs? The FDA registers this code as 46122-758-29 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 46122-0758-29. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Sympathomimetics, plain class.

Drug family (ATC) Sympathomimetics, plain, Sympathomimetics used as decongestants
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

Label name GNP MULTI-SYMPTOM RLF EYE DROP Ingredient Tetrahydrozoline/Zinc/Peg 400
📖 About the active ingredient MedlinePlus · NLM
General information about the ingredient itself — the description of this specific product follows below.

Ophthalmic tetrahydrozoline is used to relieve minor eye irritation and redness caused by colds, pollen, and swimming.

Read the full MedlinePlus article ↗
🧪 What is this product?

Good Neighbor Pharmacy Eye Drops Multi-Symptom Relief is an over-the-counter liquid eye drop product marketed as an OTC monograph drug. It contains three active ingredients that are typically used together to address minor eye discomfort. Tetrahydrozoline hydrochloride functions as a decongestant to reduce redness, while polyethylene glycol 400 and zinc sulfate act as lubricants and protectants to soothe dry, irritated eyes. This product is applied directly to the eye surface.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly $0.197 $2.95 / 15 ml
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per mL) — tap or hover for the price & month
Feb 2025 $0.197 $0.197
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
46122-0758-29 You're viewing this Main listing 1 BOTTLE, DROPPER in 1 BOX / 15 mL in 1 BOTTLE, DROPPER 2023-06-05 — Discontinued by firm

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Good Neighbor Pharmacy Eye Drops Multi-Symptom Relief 400 1 g/100mL; .05 g/100mL; .25 g/100mLthis 46122-0758-29 Amerisource 1 bottle $0.197 — Discontinued —
Rite Aid Multi-Symptom Relief Eye Drops .25 g/100mL; 400 1 g/100mL; .05 g/100mL 11822-0277-01 Rite 1 bottle — — FDA listed —
Discount Drug Mart Eye Drops Multi-Symptom Relief .25 g/100mL; 400 1 g/100mL; .05 g/100mL 53943-0490-01 Discount 1 bottle — — FDA listed —
CVS Multi-Symptom Eye Drops 400 1 g/100mL; .05 g/100mL; .25 g/100mL 69842-0884-15 CVS 1 bottle — — FDA listed —
Visine Red Eye Total Comfort Multi-Symptom .5 mg/mL; 400 10 mg/mL; 2.5 mg/mL 69968-0360-01 Kenvue 1 bottle — — FDA listed —
Meijer Multi-Symptom Relief .05 g/100mL; .25 g/100mL; 400 1 g/100mL 79481-0250-01 Meijer, 1 bottle — — FDA listed —
Equate Multi-Symptom Relief Eye Drops .25 g/100mL; 400 1 g/100mL; .05 g/100mL 79903-0159-05 Walmart, 1 bottle — — FDA listed —
Equaline Multi-Symptom Eye Drops .25 g/100mL; 400 1 g/100mL; .05 g/100mL 83455-0207-01 United 1 bottle — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2023
On the market since
Jun 2023
📍
2026
Currently FDA-listed
3 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerAmerisource Bergen Drug Corp.
FDA applicationM018 (OTC MONOGRAPH DRUG)
Labeler code46122
First marketedJun 2023
Product typeHuman Otc Drug
Portfolio3 products on file

More NDCs from Amerisource Bergen Drug Corp. labeler code 46122

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Ask a Doctor Before Use If 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Other Information 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 40 words ▾

Uses relieves dryness of the eye for temporary relief of discomfort and redness of the eye due to minor eye irritations for temporary relief of burning and irritation due to exposure to wind or sun for protection against further irritation

⏱️ Dosage and Administration 24 words ▾

Directions instill 1 to 2 drops in the affected eye(s) up to 4 times daily children under 6 years of age: ask a doctor

⚠️ Warnings 123 words ▾

Warnings For external use only Ask a doctor before use if you have narrow angle glaucoma When using this product pupils may become enlarged temporarily overuse may cause more eye redness remove contact lenses before using do not touch tip of container to any surface to avoid contamination replace cap after using do not use if this solution changes color or becomes cloudy Stop use and ask a doctor if you feel eye pain changes in vision occur redness or irritation of the eye lasts condition worsens or lasts more than 72 hours If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

🧪 Active Ingredient 12 words ▾

Active ingredients Polyethylene glycol 400 1% Tetrahydrozoline HCl 0.05% Zinc Sulfate 0.25%

🧪 Inactive Ingredients 16 words ▾

Inactive ingredients benzalkonium chloride, boric acid, edetate disodium, glycerin, hypromellose, purified water, sodium chloride, sodium citrate

🎯 Purpose 5 words ▾

Purposes Lubricant Redness Reliever Astringent

📄 Ask a Doctor Before Use If 11 words ▾

Ask a doctor before use if you have narrow angle glaucoma

📄 When Using This Product 47 words ▾

When using this product pupils may become enlarged temporarily overuse may cause more eye redness remove contact lenses before using do not touch tip of container to any surface to avoid contamination replace cap after using do not use if this solution changes color or becomes cloudy

📄 Stop Use and Ask a Doctor If 30 words ▾

Stop use and ask a doctor if you feel eye pain changes in vision occur redness or irritation of the eye lasts condition worsens or lasts more than 72 hours

🤰 If Pregnant or Breast-Feeding 10 words ▾

If pregnant or breast-feeding, ask a health professional before use.

📄 Keep Out of Reach of Children 20 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

📄 Other Information 14 words ▾

Other information some users may experience a brief tingling sensation store at 20°-25°C (68°-77°F)

📄 Questions or Comments 5 words ▾

Questions or comments? Call 1-888-527-4276

📄 Package Label / Principal Display Panel 12 words ▾

GNP Eye Drops Multi-Symptom Relief 15mL GNP Eye Drops Multi-Symptom Relief 15mL

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) ✓ Available
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Who lists this product with the FDA?
Amerisource Bergen Drug Corp. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 46122-0757-37 · Amerisource 46122-0759-29 · AmerisourceBergen →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.