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Sore Throat ReadyInCase Phenol 1.4 g/100mL Spray, 177 mL

by P & L Development, LLC · 177 mL in 1 BOTTLE, SPRAY (49580-0376-6)
NDC 49580-0376-06
🏷️ FDA NDC (as labeled) 49580-0376-6 billing pads the package segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 49580-0376-6
Product NDC 49580-0376
11-digit billing NDC 49580037606
RxCUI 198776
UNII 339NCG44TV
UPC 0715256745062
Application # M022
SPL Set ID 2fb3d17e-8ca3-4edb-8b82-4b484f42616e
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2014-11-30
Route ORAL
Dosage form SPRAY
Substance PHENOL
Why two NDCs? The FDA registers this code as 49580-0376-6 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 49580-0376-06. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Sclerosing agents for local injection class.

Drug family (ATC) Sclerosing agents for local injection, Phenol and derivatives, Other local anesthetics
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerP & L Development, LLC
FDA applicationM022 (OTC MONOGRAPH DRUG)
Labeler code49580
First marketedNov 2014
Product typeHuman Otc Drug
Portfolio124 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • Phenol is an anesthetic and antiseptic ingredient, meaning it temporarily numbs the area where you apply it and may help reduce minor surface irritation. It's designed to give you...
  • What is phenol actually doing when I spray it on my sore throat?
  • For products like Chloraseptic sprays, you should hold it in place for at least 15 seconds before spitting it out — that gives the ingredient time to work on the affected area. You...
  • How long should I hold the spray in my mouth before spitting it out?
📖 Read our full Phenol guide →
3
Nutrient depletion considerations

Phenolphthalein may be associated with lower levels of 3 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Phenolphthalein nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

FlavorCherry
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
  • UNII WZB9127XOA
    A synthetic red dye used to color medications and make them easier to identify. It serves as a colorant in tablets, capsules, and liquid formulations.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII SB8ZUX40TY
    Saccharin sodium is an artificial sweetener made from saccharin salt. It's added to medicines to improve taste, especially in liquid formulations for children or bitter drugs.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

5 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesalcohol, FD&C red no. 40, flavor, glycerin, purified water, saccharin sodium anhydrous

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Sore Throat Cherry 1.4 g/100mL 63868-0811-55 QUALITY 177 ml $0.011 — FDA listed —
Rugby Cherry Flavor 1.4 g/100mL 00536-1228-58 RUGBY 177 ml $0.012 — Availability likely —
Sore Throat Cherry 1.5 g/100mL 00904-6305-21 Major 177 ml $0.012 — Availability likely —
Good Neighbor Sore Throat Cherry Flavor 1.4 g/100mL 46122-0748-76 AMERISOURCE 177 ml $0.012 — Availability likely —
ABC Sore Throat Menthol Flavor 1.4 g/100mL 46122-0749-76 AMERISOURCE 177 ml $0.012 — Availability likely —
Sore Throat Relief Cherry Flavor 1.4 g/100mL 70000-0458-01 Cardinal 177 ml $0.012 — Availability likely —
QUALITY CHOICE Sore Throat 1.4 g/100mL 83324-0275-06 CHAIN 177 ml $0.012 — Availability likely —
Sore throat cherry 1.4 g/100mL 00363-0376-06 Walgreens 177 ml — — FDA listed —
Walgreens Sore Throat Cherry Flavor 1.4 g/100mL 00363-7030-06 WALGREEN 177 ml — — FDA listed —
Sore Throat 1.4 g/100mL 11822-3109-08 Rite 177 ml — — FDA listed —
Signature Care Sore Throat Cherry Flavor 1.4 g/100mL 21130-0196-06 SAFEWAY 177 ml — — FDA listed —
Sore Throat 1.4 g/100mL 21130-0376-06 Safeway, 177 ml — — FDA listed —
TopCare Cherry Flavor 1.4 g/100mL 36800-0600-06 TOPCO 177 ml — — FDA listed —
Topcare Sore Throat Menthol Flavor 1.4 g/100mL 36800-0606-06 TOPCO 177 ml — — FDA listed —
HEB Sore Throat Cherry Flavor 1.4 g/100mL 37808-0803-06 HEB 177 ml — — FDA listed —
HEB Sore Throat Menthol Flavor 1.4 g/100mL 37808-0805-06 HEB 177 ml — — FDA listed —
PUBLIX Sore Throat Menthol Flavor 1.4 g/100mL 41415-0307-06 PUBLIX 177 ml — — FDA listed —
PUBLIX Sore Throat Fast Relief Oral Anesthetic 1.4 g/100mL 41415-0703-06 PUBLIX 177 ml — — FDA listed —
Sore Throat 1.4 g/100mL 49035-0376-06 EQUATE 177 ml — — FDA listed —
Sore Throat ReadyInCase 1.4 g/100mLthis 49580-0376-06 P 177 ml — — FDA listed —
CVS Sore Throat Cherry 1.4 g/100mL 51316-0306-06 CVS 177 ml — — FDA listed —
CVS Sore Throat Menthol Flavor 1.4 g/100mL 51316-0307-06 CVS 177 ml — — FDA listed —
Sore Throat Cherry 1.4 g/100mL 55319-0376-06 Family 177 ml — — FDA listed —
Sore throat cherry 1.4 g/100mL 55910-0376-06 Dolgencorp, 177 ml — — FDA listed —
Sore Throat Menthol 1.4 g/100mL 56062-0377-06 Publix 177 ml — — FDA listed —
CVS Health Sore Throat Fast Relief Oral Anesthetic 1.4 g/100mL 59779-0895-06 CVS 177 ml — — FDA listed —
Diabetic Tussin Sore Throat Cherry 1.4 mg/mL 61787-0066-06 MEDTECH 177 ml — — FDA listed —
Sore Throat Relief Cherry 1.4 g/100mL 63941-0376-06 Best 177 ml — — FDA listed —
Sore Throat Relief 1.4 g/100mL 67091-0267-17 WinCo 177 ml — — FDA listed —
Chloraseptic Childrens Sore Throat Cherry 1.4 g/100mL 67172-0930-06 Prestige 177 ml — — FDA listed —
Sore Throat Relief Cherry Flavor 1.4 g/100mL 68016-0342-06 Chain 177 ml — — FDA listed —
Sore Throat Relief Menthol 1.4 g/100mL 68016-0343-06 Chain 177 ml — — FDA listed —
DRx Choice Sore Throat Menthol Flavor 1.4 g/100mL 68163-0307-06 RARITAN 177 ml — — FDA listed —
Sore Throat 1.4 g/100mL 68163-0703-06 Raritan 177 ml — — FDA listed —
NICE SORE THROAT Cherry 1.4 g/100mL 69626-0047-06 Leosons 177 ml — — FDA listed —
Phenol 14 mg/100mL 83324-0031-06 CHAIN 177 ml — — FDA listed —
Chloraseptic Sore Throat Menthol 1.4 g/100mL 67172-0113-31 Prestige 177 ml — — FDA listed —
Meijer Sore Throat 1.4 g/100mL 41250-0632-06 MEIJER 177 ml — — FDA listed —
Chloraseptic Sore Throat Cherry 1.4 g/100mL 67172-0111-31 Prestige 177 ml — — FDA listed —
Chloraseptic Sore Throat Citrus 1.4 g/100mL 67172-0112-31 Prestige 177 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2014
On the market since
Nov 2014
📍
2026
Currently FDA-listed
12 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Sore Throat ReadyInCase (this brand).

Top reported reactions

Dyspnoea20
Vomiting19
Acute Kidney Injury18
Diarrhoea16
Fatigue16
Nausea16
Abdominal Pain14

Age at onset

Child2
Adolescent1
Adult22
Elderly15

Reporter sex

250 reports
Male · 39%
Female · 61%

Serious outcomes

Hospitalization120
Death60
Life-threatening22
Disabling10
Reports over time (by year) — tap or hover for the count & year
2023 2024 2025 2026 21 6
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
49580-0376-06 You're viewing this 177 mL in 1 BOTTLE, SPRAY (49580-0376-6) 2014-11-30 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 49580-0376-6, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 49580-0376-06, written without dashes as 49580037606. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 49580-0376-06, the first segment (49580) is the labeler code FDA assigned to P & L Development, LLC; the middle segment (0376) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (06) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by P & L Development, LLC. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
P & L Development, LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 15 words ▾

Uses for the temporary relief of occasional minor irritation, pain, sore mouth, and sore throat

⏱️ Dosage and Administration 67 words ▾

Directions adults and children 2 years of age and older: apply to affected area (one spray) allow to remain in place for at least 15 seconds, than spit out use every 2 hours or as directed by a dentist or doctor children under 12 years of age should be supervised in the use of this product children under 2 years of age: consult a dentist or doctor

⚠️ Warnings 126 words ▾

Warnings Sore throat warning: Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult a doctor promptly. Do not use more than 2 days.

When using this product, do not exceed recommended dose. Stop use and ask a doctor if sore throat is severe, or lasts for more than 2 days sore mouth symptoms do not improve in 7 days irritation, pain or redness persists or worsens fever, headache, rash, swelling, nausea or vomiting develops If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.

If more than used for minor mouth or throat pain is accidentally swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

📦 Storage and Handling 9 words ▾

Other information store between 20-25ºC (68-77ºF). Do not refrigerate.

🧪 Active Ingredient 4 words ▾

Active ingredient Phenol 1.4%

🧪 Inactive Ingredients 14 words ▾

Inactive ingredients alcohol, FD&C red no. 40, flavor, glycerin, purified water, saccharin sodium anhydrous

🎯 Purpose 3 words ▾

Purpose Oral Anesthetic/Analgesic

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 49580-0346-02 · P 49580-0379-04 · P →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.