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mucus d guaifenesin, pseudoephedrine hydrochloride 1200 mg; 120 mg Tablet, Multilayer, Extended Release — NDC 51316-345-62 (Billing 51316-0345-62)

by CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED · 4 BLISTER PACK in 1 CARTON / 6 TABLET, MULTILAYER, EXTENDED RELEASE in 1 BLISTER PACK

This is a package of mucus d guaifenesin, pseudoephedrine hydrochloride 1200 mg; 120 mg Tablet, Multilayer, Extended Release from CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED, marketed since Apr 2025 and currently FDA-listed. It is this product's only package size.

NDC 51316-0345-62
🏷️ FDA NDC (as labeled) 51316-345-62 billing pads the product segment with a zero
OTC Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 51316-345-62
Product NDC 51316-345
11-digit billing NDC 51316034562
RxCUI 1244675
UNII 495W7451VQ, 6V9V2RYJ8N
Application # ANDA214407
SPL Set ID c8026a56-4249-48de-b763-2d1c55731733
Established class (EPC) Expectorant
Physiologic effect Decreased Respiratory Secretion Viscosity; Increased Respiratory Secretions
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2025-04-04
Route ORAL
Dosage form TABLET, MULTILAYER, EXTENDED RELEASE
Substance GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Quick answers
  • RxCUI (RxNorm): 1244675
Why two NDCs? The FDA registers this code as 51316-345-62 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 51316-0345-62. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Expectorant class.

Pharmacologic class Expectorant
Drug family (ATC) Expectorants
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It helps loosen chest mucus so your cough is more productive. It also temporarily relieves nasal and sinus congestion from a cold, hay fever or other upper respiratory allergies.
  • Swallow them whole with a full glass of water. Don't crush, chew or break them. You can take them with or without food, and they're usually taken about every 12 hours. Follow the p...
  • How should I take the extended-release tablets?
  • Be careful here. If your medicine is an MAOI, you shouldn't take this product, or for 2 weeks after stopping the MAOI. If you aren't sure what your prescription is, ask me before y...
📖 Read our full Guaifenesin / Pseudoephedrine guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
51316-0345-62 You're viewing this Main listing 4 BLISTER PACK in 1 CARTON / 6 TABLET, MULTILAYER, EXTENDED RELEASE in 1 BLISTER PACK 2025-04-04 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Mucus D 1200 mg/1; 120 mg 00113-8911-62 L. 6 tablets $0.423 — Availability likely —
Leader Mucus Relief D 1200 mg/1; 120 mg 70000-0719-01 Cardinal 6 tablets $0.423 — Availability likely —
foster and thrive mucus relief d 1200 mg/1; 120 mg 70677-1273-01 Strategic 6 tablets $0.423 — Availability likely —
Mucinex D Maximum Strength 1200 mg/1; 120 mg 63824-0041-12 Reckitt 12 tablets $0.979 — Discontinued —
Guaifenesin and Pseudoephedrine HCl 1200 mg/1; 120 mg 00363-0134-78 WALGREEN 12 tablets — — FDA listed —
mucus relief d 1200 mg/1; 120 mg 00363-2389-62 Walgreen 6 tablets — — FDA listed —
Mucus Relief D 1200 mg/1; 120 mg 00363-7064-24 Walgreens 6 tablets — — FDA listed —
Mucus Relief D 1200 mg/1; 120 mg 11822-7399-04 Rite 6 tablets — — FDA listed —
Mucus Relief D 1200 mg/1; 120 mg 49035-0261-12 Wal-mart 12 tablets — — FDA listed —
mucus d 1200 mg/1; 120 mgthis 51316-0345-62 CVS 6 tablets — — FDA listed —
MAXIMUM STRENGTH Mucus D 1200 mg/1; 120 mg 51316-0970-24 CVS 24 tablets — — FDA listed —
Guaifenesin and Pseudoephedrine HCl 1200 mg/1; 120 mg 51660-0077-12 Ohm 12 tablets — — FDA listed —
Guaifenesin and Pseudoephedrine HCL 1200 mg/1; 120 mg 55111-0799-04 Dr. 6 tablets — — FDA listed —
nasal and chest decongestant 1200 mg/1; 120 mg 56062-0614-62 Publix 6 tablets — — FDA listed —
Guaifenesin and Pseudoephedrine HCl 1200 mg/1; 120 mg 58602-0834-77 Aurohealth 12 tablets — — FDA listed —
mucus relief d 1200 mg/1; 120 mg 59640-0300-62 H 6 tablets — — FDA listed —
Guaifenesin and Pseudoephedrine HCl 1200 mg/1; 120 mg 62207-0828-71 Granules 10 tablets — — FDA listed —
Mucus Relief D 1200 mg/1; 120 mg 69842-0211-24 CVS 6 tablets — — FDA listed —
mucus D 1200 mg/1; 120 mg 79481-0119-00 Meijer, 3 tablets — — FDA listed —
Equate Mucus D 1200 mg/1; 120 mg 79903-0388-24 WALMART 6 tablets — — FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2025
On the market since
Apr 2025
📍
2026
Currently FDA-listed
1 year listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color Orange
ShapeOval
ImprintL12
Size22 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerCVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED
Application holderL PERRIGO CO
FDA applicationANDA214407 (ANDA)
Labeler code51316
First marketedApr 2025
Product typeHuman Otc Drug
Portfolio119 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Other Information 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 61 words ▾

Uses • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive • temporarily relieves nasal congestion due to • common cold • hay fever • upper respiratory allergies • temporarily restores freer breathing through the nose • promotes nasal and/or sinus drainage • temporarily relieves sinus congestion and pressure

⏱️ Dosage and Administration 63 words ▾

Directions • do not crush, chew, or break extended-release tablet • take with a full glass of water • this product can be administered without regard for timing of meals • adults and children 12 years and older: 1 extended-release tablet every 12 hours; not more than 2 extended-release tablets in 24 hours • children under 12 years of age: do not use

⚠️ Warnings 193 words ▾

Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have • heart disease • high blood pressure • thyroid disease • diabetes • trouble urinating due to an enlarged prostate gland • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema • cough accompanied by too much phlegm (mucus) When using this product • do not use more than directed Stop use and ask a doctor if • you get nervous, dizzy, or sleepless • symptoms do not get better within 7 days, come back or occur with a fever, rash, or persistent headache.

These could be signs of a serious illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

🧪 Active Ingredient 13 words ▾

Active ingredients (in each extended-release tablet) Guaifenesin 1200 mg Pseudoephedrine HCl 120 mg

🧪 Inactive Ingredients 22 words ▾

Inactive ingredients carbomer homopolymer type B, colloidal silicon dioxide, FD&C yellow #6 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate

🎯 Purpose 4 words ▾

Purposes Expectorant Nasal Decongestant

📄 Do Not Use 55 words ▾

Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

📄 Ask a Doctor Before Use If 52 words ▾

Ask a doctor before use if you have • heart disease • high blood pressure • thyroid disease • diabetes • trouble urinating due to an enlarged prostate gland • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema • cough accompanied by too much phlegm (mucus)

📄 When Using This Product 11 words ▾

When using this product • do not use more than directed

📄 Stop Use and Ask a Doctor If 42 words ▾

Stop use and ask a doctor if • you get nervous, dizzy, or sleepless • symptoms do not get better within 7 days, come back or occur with a fever, rash, or persistent headache. These could be signs of a serious illness.

🤰 If Pregnant or Breast-Feeding 10 words ▾

If pregnant or breast-feeding, ask a health professional before use.

📄 Keep Out of Reach of Children 22 words ▾

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

📄 Other Information 7 words ▾

Other information • store at 20-25°C (68-77°F)

📄 Questions or Comments 3 words ▾

Questions or comments?

📄 Package Label / Principal Display Panel 58 words ▾

Package/Label Principal Display Panel CVS ™ 12 HR actual size Maximum Strength Mucus-D Guaifenesin & Pseudoephedrine Hydrochloride Extended-Release Tablets 1200 mg / 120 mg Expectorant, Nasal Decongestant Compare to Maximum Strength Mucinex ® D active ingredients Clears Nasal & Sinus Congestion Thins & Loosens Mucus Immediate & Extended Release Relieves Nasal & Chest Congestion 24 EXTENDED-RELEASE TABLETS cvs-mucus-d-carton-image.jpg

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 51316-0344-12 · CVS 51316-0347-05 · CVS →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.