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Muscle Rub Pain Reliever Gel MENTHOL, UNSPECIFIED FORM 25 mg/g Gel, 1 tube — NDC 52000-0072-02 package photo

Muscle Rub Pain Reliever Gel MENTHOL, UNSPECIFIED FORM 25 mg/g Gel, 1 tube

by Universal Distribution Centre LLC · 1 TUBE in 1 CARTON (52000-072-02) / 35.4 g in 1 TUBE (52000-072-01)
NDC 52000-0072-02
🏷️ FDA NDC (as labeled) 52000-072-02 billing pads the product segment with a zero
This package
Contains1 tube Pack sizes2 compare ↓
Also comes in: 35.4 g 52000-0072-04
OTC Discontinued Non-controlled ⚠ Inactivated by FDA
🗂️ Data synced Sep 17, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Excluded from the active FDA NDC Directory. FDA inactivated this product’s listing record, so it is excluded from the active NDC Directory. The listing was last certified through Dec 2025. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

🆔 Identity & classification

FDA NDC (as labeled) 52000-072-02
Product NDC 52000-072
11-digit billing NDC 52000007202
RxCUI 282805
UNII L7T10EIP3A
Application # M017
SPL Set ID b9a563b6-7988-79df-e053-2995a90a752b
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Inactivated by FDA (certified through Dec 2025)
Marketing start 2021-01-24
Route TOPICAL
Dosage form GEL
Substance MENTHOL, UNSPECIFIED FORM
Why two NDCs? The FDA registers this code as 52000-072-02 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 52000-0072-02. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerUniversal Distribution Centre LLC
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code52000
First marketedJan 2021
Product typeHuman Otc Drug
Portfolio3 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • Menthol is found in a lot of over-the-counter topical products — creams, gels, patches, sprays, and powders. Depending on the product, it's used to temporarily ease minor muscle an...
  • Start with clean, dry skin — free of lotions or creams — before applying the patch. Peel the backing off and press the sticky side firmly to the sore area. Most menthol patches sho...
  • Yes, a mild burning or tingling feeling right after applying a menthol product is common and usually settles down within a few days of regular use. What's not normal is severe burn...
  • Is that burning sensation after I apply it normal?
📖 Read our full Menthol guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 35.4 g
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Icy Hot Vanishing Scent .025 g/g 41167-0092-00 Chattem, 1 tube — — FDA listed —
2.5% Menthol PAIN RELIEF 25 mg/g 43473-0096-02 Nantong 1 tube — — FDA listed —
CAREALL Musle and Joint 25 mg/g 51824-0014-03 New 85 g — — FDA listed —
Muscle Rub Pain Reliever Gel 25 mg/gthis 52000-0072-02 Universal 1 tube — — Discontinued —
2.5% Menthol PAIN RELIEF 25 mg/g 52000-0440-02 Universal 1 tube — — FDA listed —
Family Care Muscle and Joint 25 mg/g 65923-0144-57 United 1 tube — — FDA listed —
Winco Muscle and Joint Pain Relief Gel 2oz 25 mg/g 67091-0941-02 WINCO 1 tube — — FDA listed —
Bengay Vanishing Scent 25 mg/g 69968-0595-02 Kenvue 1 tube — — FDA listed —
TheraCare Muscle and Joint Gel Vanishing Scent 2.5 g/100g 71101-0129-01 Veridian 1 tube — — FDA listed —
Pain-X 25 mg/g 80489-0003-01 OL 1 tube — — FDA listed —
Muscle Rub 25 mg/g 80489-0004-01 OL 1 tube — — FDA listed —
Thera Plus Extra Strength Muscle Rub Topical Analgesic 25 mg/g 80684-0139-00 FOURSTAR 42.5 g — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2021
On the market since
Jan 2021
📍
2026
Currently FDA-listed
5 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for MENTHOL, UNSPECIFIED FORM — the ingredient across all brands.

Top reported reactions

Pain74
Fatigue66
Diarrhoea58
Fall53
Headache51
Arthralgia48
Pain In Extremity45

Age at onset

Child3
Adolescent1
Adult44
Elderly62

Reporter sex

913 reports
Male · 26%
Female · 73%
Unknown · 0%

Serious outcomes

Hospitalization186
Reports over time (by year) — tap or hover for the count & year
2020 2022 2024 2026 97 32
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
52000-0072-02 You're viewing this 1 TUBE in 1 CARTON (52000-072-02) / 35.4 g in 1 TUBE (52000-072-01) 2021-01-24 Inactivated by FDA
52000-0072-04 1 TUBE in 1 CARTON (52000-072-04) / 35.4 g in 1 TUBE (52000-072-03) 2021-01-24 Active

Pack size FAQ

What quantity is in NDC 52000-0072-02?
NDC 52000-0072-02 contains 1 tube — 1 tube in 1 carton / 35.4 g in 1 tube.
What is the difference between NDC 52000-0072-02 and NDC 52000-0072-04?
Both are Muscle Rub Pain Reliever Gel MENTHOL, UNSPECIFIED FORM 25 mg/g Gel — the drug itself is identical. NDC 52000-0072-02 is the 1 tube package, while NDC 52000-0072-04 is the 1 tube package.
What NDC number is used to bill for this package of Muscle Rub Pain Reliever Gel MENTHOL, UNSPECIFIED FORM 25 mg/g Gel?
Bill NDC 52000-0072-02 — the 11-digit billing format is 52000007202. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 52000-072-02, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 52000-0072-02, written without dashes as 52000007202. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 52000-0072-02, the first segment (52000) is the labeler code FDA assigned to Universal Distribution Centre LLC; the middle segment (0072) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (02) identifies this exact package size and type. Together they name one specific package of one specific product.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 1 tube (52000-0072-04). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Universal Distribution Centre LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 20 words ▾

Uses temporarily relieves the minor aches and pains of muscles and joints associated with: simple backache arthritis strains bruises sprains

⏱️ Dosage and Administration 31 words ▾

Directions adults and children 12 years of age and older: apply to affected area not more than 3 to 4 times daily children under 12 years of age: ask a doctor

⚠️ Warnings 106 words ▾

Warnings For external use only. Do not use on wounds or damaged skin with a heating pad on a child under 12 years of age with arthritis-like conditions Ask a doctor before use if you have redness over the affected area When using this product avoid contact with eyes or mucous membranes do not bandage tightly Stop use and ask a doctor if condition worsens or symptoms persist for more than 7 days symptoms clear up and occur again within a few days excessive skin irritation occurs Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 10 words ▾

Other information store at 20° to 25°C (68° to 77°F)

🧪 Active Ingredient 4 words ▾

Active ingredient Menthol 2.5%

🧪 Inactive Ingredients 16 words ▾

Inactive ingredients camphor, carbomer, DMDM hydantoin, isoceteth-20, isopropyl alcohol, PEG-40 hydrogenated castor oil, sodium hydroxide, water

🎯 Purpose 3 words ▾

Purpose Topical analgesic

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 52000-0071-02 · Universal 52000-0073-02 · Universal →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.