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Sei Bella Clarity Clear Refining Foaming Cleanser Acne treatment Salicylic Acid 1.8 g/180mL Liquid, 180 mL

by Melaleuca, Inc. · 180 mL in 1 BOTTLE, DISPENSING (54473-401-01)
NDC 54473-0401-01
🏷️ FDA NDC (as labeled) 54473-401-01 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 54473-401-01
Product NDC 54473-401
11-digit billing NDC 54473040101
RxCUI 1038982
UNII O414PZ4LPZ
Application # M006
SPL Set ID 19370e9a-4907-2ddc-e063-6294a90a9711
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2024-01-01
Route TOPICAL
Dosage form LIQUID
Substance SALICYLIC ACID
Why two NDCs? The FDA registers this code as 54473-401-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 54473-0401-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Salicylic acid and derivatives class.

Drug family (ATC) Salicylic acid and derivatives, Other antifungals for topical use, Antiinflammatory agents, non-steroids
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerMelaleuca, Inc.
FDA applicationM006 (OTC MONOGRAPH DRUG)
Labeler code54473
First marketedJan 2024
Product typeHuman Otc Drug
Portfolio22 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • It's designed to treat acne. Salicylic acid helps by loosening and removing dead skin cells that clog pores — the buildup that leads to breakouts. The multi-step system on this lab...
  • What is this salicylic acid product actually supposed to do for my skin?
  • Some mild tingling, stinging, and peeling is actually expected — that's the salicylic acid doing its job by clearing away dead skin cells. But if the burning or peeling feels exces...
  • My skin feels like it's burning and peeling. Is that normal?
📖 Read our full Salicylic Acid Topical guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII MA36MNW77O
    A natural plant material derived from apple skin, used as a source of fiber, color, and texture in the medicine. It may help the tablet hold together and provide bulk to the formulation.
  • UNII LKG8494WBH
    Benzyl alcohol is a clear liquid used as a preservative and solvent in medicines. It helps prevent bacterial and fungal growth and dissolves other ingredients to create uniform liquid formulations.
  • UNII 0451R360HR
    A mild, plant-derived cleaning agent made from coconut oil and sugar. It's used in formulations as a surfactant and emulsifier to help mix ingredients together and improve how the medicine spreads or dissolves.
  • UNII RYQ4R60M02
    A green algae ingredient used as a natural colorant and nutritional filler in supplements and medications. It adds color and bulk to tablets and capsules.
  • UNII 2968PHW8QP
    A weak organic acid derived from citrus fruits or made through fermentation. It works as a buffer to control pH, a preservative to extend shelf life, and a flavoring agent in medications.
  • UNII ICS790225B
    A plant-derived cleaning agent made from coconut oil and glucose. It works as a surfactant and emulsifier to help mix oil and water-based ingredients together in the formulation.
  • UNII 03DH2IZ3FY
    A mild cleansing agent derived from coconut oil. It's used in medicines as a surfactant to help dissolve or distribute other ingredients evenly throughout the formulation.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 4PC054V79P
    A fatty acid derived from glycerin and oleic acid (a natural oil component). It acts as an emulsifier to help mix oil and water-based ingredients, and serves as a lubricant and surfactant in the formulation.
  • UNII SC667B999P
    A plant-derived surfactant made from coconut or palm oils combined with glucose. It helps other ingredients mix evenly and improves how the medicine spreads or dissolves in the body.
  • UNII 25X51I8RD4
    Niacinamide is a form of vitamin B3, a water-soluble nutrient. In medicines, it may be added as a nutritional supplement or to support skin health, though its primary role here is as an active ingredient rather than a traditional inactive filler.
  • UNII WV9CM0O67Z
    Panthenol is a humectant and skin-conditioning agent derived from pantothenic acid. It's added to medicines to help retain moisture and soothe skin irritation.
  • UNII BMT4RCZ3HG
    Sodium cocoyl glutamate is a mild cleanser derived from coconut oil and amino acids. It's used in medicines as a surfactant to help dissolve and distribute active ingredients evenly throughout the formulation.
  • UNII 05I15JNI2J
    A synthetic polymer that absorbs and holds moisture. Used in tablets and capsules as a super-disintegrant to help the medicine break apart quickly when swallowed, allowing faster drug release.
  • UNII R0ZB2556P8
    Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
  • UNII YA22H34H9Q
    A chelating agent derived from sodium and organic compounds. It binds to metal ions in the formulation to improve stability and prevent unwanted chemical reactions that could degrade the medicine.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

18 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesAqua (Water/Eau), Sodium Cocoyl Glutamate, Glycerin, Lauroyl/Myristoyl Methyl Glucamide, Pyrus Malus Fruit Extract, Coco-Betaine, Niacinamide, Panthenol, Salicylic Acid, Sodium Polyacrylate, Benzyl Alcohol, Capryloyl/Caproyl Methyl Glucamide, Coco-Glucoside, Glyceryl Oleate, Citric Acid, Ethylhexylglycerin, Trisodium Ethylenediamine Disuccinate, Chlorella Vulgaris, Extract, Tocopherol

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Proactivplus Smoothing BHA Cleanser 10 mg/mL 11410-0216-01 Alchemee, 1 tube — — FDA listed —
Acne Advanced Cleansing 10 mg/mL 15751-3010-05 Eminence 1 bottle — — FDA listed —
Nas Pore Refining Scrub 1 g/100g 26052-0040-01 BURT'S 110 g — — FDA listed —
blackhead solutions 7 day deep pore cleanse and scrub acne medication 10 mg/mL 49527-0062-02 CLINIQUE 1 tube — — Discontinued —
clear days ahead oil-free salicylic acid acne treatment cleanser 2.4 g/240mL 50184-1005-01 Philosophy 240 ml — — FDA listed —
Sei Bella Clarity Clear Refining Foaming Cleanser Acne treatment 1.8 g/180mLthis 54473-0401-01 Melaleuca, 180 ml — — FDA listed —
Acne wash facial cleanser pink grapefruit 2 g/200mL 57337-0080-01 Rejoice 200 ml — — FDA listed —
Acne wash facial cleanser Tea tree oil 2 g/200mL 57337-0081-01 Rejoice 200 ml — — FDA listed —
Clear Improvement Blackhead Clearing Mask To Scrub 10 mg/mL 59427-0118-01 ORIGINS 75 ml — — FDA listed —
Dove 1 g/100mL 64942-2074-01 CONOPCO 512 ml — — FDA listed —
Dove 1 g/100mL 64942-2093-01 CONOPCO 500 ml — — Discontinued —
Neutrogena Stubborn Texture Daily Cleanser 10 mg/mL 69968-0704-06 Kenvue 186 ml — — FDA listed —
Neutrogena Stubborn Body Acne Cleanser and Exfoliator 10 mg/mL 69968-0759-08 Kenvue 250 ml — — FDA listed —
NAELI Exfoliator AHA-BHA Face Cleanser 10 mg/mL 73670-0606-00 ALLI 1 bottle — — FDA listed —
NAELI Exfoliator AHA BHA Face Cleanser 10 mg/mL 73670-0620-00 ALLI 1 bottle — — FDA listed —
Acne Clarifying Cleanser 10 mg/mL 76354-0415-01 e.l.f. 1 bottle — — FDA listed —
Acne Wash 1 mg/100mg 82442-0805-01 Target 650 mg — — FDA listed —
bareMinerals Blemish Remedy Acne Treatment Gelee Cleanser 10 mg/g 98132-0770-01 Orveon 1 tube — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2024
On the market since
Jan 2024
📍
2026
Currently FDA-listed
2 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📊 Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Salicylic Acid (matched by generic name) — the program that covers self-administered drugs. 2 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Salicylic Acid. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$11.2K
Claims incl. refills
43
Beneficiaries
35
Spend / beneficiary
$319.01
Spend / claim
$259.66
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
54473-0401-01 You're viewing this 180 mL in 1 BOTTLE, DISPENSING (54473-401-01) 2024-01-01 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 54473-401-01, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 54473-0401-01, written without dashes as 54473040101. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 54473-0401-01, the first segment (54473) is the labeler code FDA assigned to Melaleuca, Inc.; the middle segment (0401) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Melaleuca, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Melaleuca, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 12 words ▾

Uses treats acne clears acne blemishes helps control development of new blemishes

⏱️ Dosage and Administration 57 words ▾

Directions wet face pump dispenser 2-3 times onto palms of hands massage onto the face avoiding the eye area use morning and night if excessive drying of the skin occurs, start with one application daily and then gradually increase if needed if bothersome peeling or dryness occurs, reduce application to once a day or every other day

⚠️ Warnings 18 words ▾

Warnings For external use only Do not get into eyes. If contact occurs, rinse eyes thoroughly with water.

🧪 Active Ingredient 5 words ▾

Active Ingredients Salicylic Acid 1%

🧪 Inactive Ingredients 38 words ▾

Aqua (Water/Eau), Sodium Cocoyl Glutamate, Glycerin, Lauroyl/Myristoyl Methyl Glucamide, Pyrus Malus Fruit Extract, Coco-Betaine, Niacinamide, Panthenol, Salicylic Acid, Sodium Polyacrylate, Benzyl Alcohol, Capryloyl/Caproyl Methyl Glucamide, Coco-Glucoside, Glyceryl Oleate, Citric Acid, Ethylhexylglycerin, Trisodium Ethylenediamine Disuccinate, Chlorella Vulgaris, Extract, Tocopherol

🎯 Purpose 3 words ▾

Purpose Acne treatment

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 54473-0400-01 · Melaleuca, 54473-0402-01 · Melaleuca, →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.