Bisacodyl 10 mg Suppository, 12 suppositories
by Rising Pharma Holdings, Inc. · 3 BLISTER PACK in 1 CARTON (57237-327-21) / 4 SUPPOSITORY in 1 BLISTER PACK (57237-327-04)
NDC 57237-0327-21
🏷️ FDA NDC (as labeled)
57237-327-21
billing pads the product segment with a zero
This package
Contains12 suppositories
Cost per ea$0.3207 NADAC
Per package$3.85 / 12 suppositories
Pack sizes2 compare ↓
Also priced by: Medicaid pays $0.5304/unit — full pricing hub ↓
Also comes in:
30 suppositories 57237-0327-03
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
57237-327-21
Product NDC
57237-327
11-digit billing NDC
57237032721
NCPDP billing unit
EA — each (per item)
RxCUI
198509
UNII
10X0709Y6I
UPC
0357237327210
Application #
M007
SPL Set ID
03429da4-1ce9-4789-bf54-ce1b3215b013
Established class (EPC)
Stimulant Laxative
Physiologic effect
Increased Large Intestinal Motility; Stimulation Large Intestine Fluid/Electrolyte Secretion
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2023-08-24
Marketing end
2026-10-31
Route
RECTAL
Dosage form
SUPPOSITORY
Substance
BISACODYL
GPI-14
46200010005205
GCN Seq No
002944
GCN
08731
HICL code
001301
Ingredient (HICL)
Bisacodyl
HIC1 code
Q
Therapeutic class — broad (HIC1)
Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code
Q3
Therapeutic class — intermediate (HIC2)
Anal-Rectal Preparations
HIC3 code
Q3S
Therapeutic class — specific (HIC3)
Laxatives, Local/Rectal
AHFS code
56:12.00.00
AHFS class
Cathartics And Laxatives
FDB label name
BISACODYL 10 MG SUPPOSITORY
FDB brand name
Bisacodyl
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 57237-327-21 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 57237-0327-21. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Stimulant Laxative class.
Pharmacologic class
Stimulant Laxative
Drug family (ATC)
Contact laxatives, Enemas
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerRising Pharma Holdings, Inc.
FDA applicationM007 (OTC MONOGRAPH DRUG)
Labeler code57237
First marketedAug 2023
Product typeHuman Otc Drug
Portfolio525 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name BISACODYL 10 MG SUPPOSITORY Ingredient Bisacodyl
📗 Our plain-language guide HelloPharmacist
- It depends on which form you're using. Oral tablets (like Dulcolax Stimulant Laxative) usually take 6 to 12 hours, so many people take them at bedtime and get results in the mornin...
- No — it's really important not to chew, crush, or break bisacodyl tablets. They have a special protective coating that helps them reach the right part of your gut without irritatin...
- Can I chew or crush the tablet if I have trouble swallowing?
- Milk and antacids can break down the protective coating on bisacodyl tablets too soon, before the medicine reaches where it needs to work. This can cause stomach irritation and mak...
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Bisacodyl — tap one for details:
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Bisacodyl?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Color
white
ShapeBullet
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII 8334LX7S21
A solid fat derived from animal or vegetable sources, used as a coating agent and lubricant to help pills slide smoothly during manufacturing and protect the medicine from moisture and air.
1 inactive ingredient listed in the exact product block matched to this NDC.
The official label also statesInactive ingredient hard fat
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per ea | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.321 | $3.85 / 12 suppositories |
| Medicaid paysCMS SDUD · 12 mo | $0.5304 | $6.36 / 12 suppositories |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per ea) — tap or hover for the price & month
▼ Down 11% over the last 9 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Bisacodyl 10 mg 00574-7050-12 | Padagis | 12 suppositories | $0.321 | — | Availability likely | — |
| Bisacodyl 10 mg 00904-7142-12 | Major | 12 suppositories | $0.321 | — | Availability likely | — |
| Good Neighbor Pharmacy Gentle Laxative 10 mg/2000mg 46122-0608-51 | AmerisourceBergen | 40 mg | $0.321 | — | Availability likely | — |
| Bisacodyl 10 mgthis 57237-0327-21 | Rising | 12 suppositories | $0.321 | — | Availability likely | — |
| Proctozone-B 10 mg 57237-0337-03 | Rising | 30 suppositories | $0.321 | — | Availability likely | — |
| Bisacodyl 10 mg 70000-0573-01 | Cardinal | 4 suppositories | $0.321 | — | Availability likely | — |
| Foster and Thrive Gentle Laxative 10 mg/2000mg 70677-1091-01 | Strategic | 40 mg | $0.321 | — | Availability likely | — |
| Walgreens Gentle Laxative 10 mg 00363-0466-04 | Walgreens | 40 mg | — | — | FDA listed | — |
| Walgreens Gentle Laxative 10 mg 00363-0468-04 | Walgreens | 4 suppositories | — | — | FDA listed | — |
| Rite-Aid Gentle Laxative 10 mg 11822-4890-05 | RITE | 8 suppositories | — | — | FDA listed | — |
| Gentle Laxative Bisacodyl 10 mg 13709-0321-01 | NeilMed | 30 capsules | — | — | FDA listed | — |
| Bisacodyl Laxative 10 mg/1.8g 13709-0328-01 | Neilmed | 1.8 g | — | — | FDA listed | — |
| HEB Gentle Laxative 10 mg/2000mg 37808-0877-08 | H | 40 mg | — | — | FDA listed | — |
| Dulcolax Laxative 10 mg 41167-0210-01 | Chattem, | 4 suppositories | — | — | FDA listed | — |
| Meijer Gentle Laxative 10 mg/2000mg 41250-0665-04 | Meijer | 40 mg | — | — | FDA listed | — |
| Discount Drugmart Gentle Laxative 10 mg/2000mg 53943-0805-08 | Discount | 40 mg | — | — | FDA listed | — |
| Dollar General Gentle Laxative 10 mg/2000mg 55910-0457-04 | Dolgencorp, | 40 mg | — | — | FDA listed | — |
| Bisacodyl 10 mg 57896-0443-01 | GERI-CARE | 100 suppositories | — | — | FDA listed | — |
| Stratuscare Bisacodyl 10 mg 58980-0415-04 | Stratus | 4 suppositories | — | — | FDA listed | — |
| CVS Gentle Laxative 10 mg 59779-0107-09 | CVS | 8 suppositories | — | — | FDA listed | — |
| Bisacodyl 10 mg 68016-0084-08 | Pharmacy | 8 suppositories | — | — | FDA listed | — |
| Bisacodyl 10 mg 69842-0816-04 | CVS | 4 suppositories | — | — | FDA listed | — |
| Laxative 10 mg 70795-1010-01 | GRAXCELL | 100 suppositories | — | — | FDA listed | — |
| OneLAX 10 mg 71399-8460-02 | AKRON | 12 suppositories | — | — | FDA listed | — |
| Conlax 10 mg 72701-0102-04 | Bliss | 4 suppositories | — | — | FDA listed | — |
| Bisacodyl 10 mg 82568-0028-02 | AARNA | 12 suppositories | — | — | FDA listed | — |
| Bisacodyl 10 mg 83720-0550-25 | Oncor | 12 suppositories | — | — | FDA listed | — |
| Bisacodyl Laxative 10 mg 71457-0501-01 | InvaDerm | 102 suppositories | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2023
On the market since
Aug 2023
📍
2026
Currently FDA-listed
3 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🗺️ Medicaid utilization & spend
📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 57237-0327-21, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q4 2025 · 4 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
7.3K
Units reimbursed last 4 qtrs
133.1K
Gross reimbursed last 4 qtrs
$70.6K
Avg / prescription
$9.62
Avg / unit
$0.5304
Latest quarter Q4 2025
1.5KRx
Medicaid pays / ea
$0.5304
gross reimbursed
vs
NADAC / ea
$0.3207
acquisition cost
=
Spread
+$0.2097
+65% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
Fee-for-service · 3,680 Rx Managed care · 3,656 Rx
State Medicaid map
Units reimbursed · per 100k residents
13.1516
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
Prescriptions—
Units—
Reimbursed—
🏆 Top states by units · per 100k residents
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.
💊 Medicaid utilization by pack size
Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
Drug total (last 4 qtrs): 10,393 Rx · 200,939 units · $108,599 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.
📦 Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Status |
|---|---|---|---|---|---|
| 57237-0327-03 | 6 BLISTER PACK in 1 CARTON (57237-327-03) / 5 SUPPOSITORY in 1 BLISTER PACK (57237-327-51) | $0.3207 / ea | $9.62 | 2023-08-24 | Active |
| 57237-0327-21 You're viewing this | 3 BLISTER PACK in 1 CARTON (57237-327-21) / 4 SUPPOSITORY in 1 BLISTER PACK (57237-327-04) | $0.3207 / ea | $3.85 | 2023-08-24 | Active |
This pack effectively ties for the lowest per-ea cost of the 2 priced pack sizes ($0.3207 NADAC).
In Medicaid, this is the most-dispensed pack of this product — about 71% of fills over the last four reported quarters. See all packs ↓
Pack size FAQ
What quantity is in NDC 57237-0327-21?
NDC 57237-0327-21 contains 12 suppositories — 3 blister pack in 1 carton / 4 suppository in 1 blister pack.
What is the difference between NDC 57237-0327-21 and NDC 57237-0327-03?
Both are Bisacodyl 10 mg Suppository — the drug itself is identical. NDC 57237-0327-21 is the 12 suppositories package, while NDC 57237-0327-03 is the 30 suppositories package.
What NDC number is used to bill for this package of Bisacodyl 10 mg Suppository?
Bill NDC 57237-0327-21 — the 11-digit billing format is 57237032721. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Use for relief of occasional constipation (irregularity) this product generally produces bowel movement in 15 minutes to 1 hour
⏱️ Dosage and Administration ▾
Directions adults and children 12 years of age and over 1 suppository in a single daily dose. Peel open plastic. Insert suppository well into rectum, pointed end first. Retain about 15 to 20 minutes children 6 to under 12 years 1/2 suppository in a single daily dose children under 6 years Do not use
⚠️ Warnings ▾
Warnings For rectal use only
📦 Storage and Handling ▾
Other information store at 20-25°C (68-77°F) if suppository softens prior to use, may be placed in refrigerator for short time
🧪 Active Ingredient ▾
Active ingredient (in each suppository) Bisacodyl USP, 10 mg
🧪 Inactive Ingredients ▾
Inactive ingredient hard fat
🎯 Purpose ▾
Purpose Stimulant Laxative
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.