Home › NDC Lookup › Ingredients › Avobenzone Homosalate Octisalate Octocry... › 57627-0204-01
🧴image loading
(from DailyMed)

ANTI-AGING COMPLEX BROAD SPECTRUM SPF 30 Avobenzone, Homosalate, Octisalate, Octocrylene, Oxybenzone 4 g/100g; 2.35 g/100g; 5 g/100g; 3 g/100g; 8 g/100g Cream, 31 g — NDC 57627-204-01 (Billing 57627-0204-01)

by Merle Norman Cosmetics, Inc. · 31 g in 1 BOTTLE, PUMP (57627-204-01)

NDC 57627-204-01 (billing 57627-0204-01) is a package of 31 g of ANTI-AGING COMPLEX BROAD SPECTRUM SPF 30 Avobenzone, Homosalate, Octisalate, Octocrylene, Oxybenzone 4 g/100g; 2.35 g/100g; 5 g/100g; 3 g/100g; 8 g/100g Cream from Merle Norman Cosmetics, Inc., marketed since Nov 2021 and currently FDA-listed.

NDC 57627-0204-01
🏷️ FDA NDC (as labeled) 57627-204-01 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 57627-204-01
Product NDC 57627-204
11-digit billing NDC 57627020401
UNII 4X49Y0596W, 5A68WGF6WM, 95OOS7VE0Y, G63QQF2NOX, V06SV4M95S
UPC 0885682027640
Application # M020
SPL Set ID d10272ea-aedd-5759-e053-2a95a90a3ab3
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2021-11-29
Route TOPICAL
Dosage form CREAM
Substance OCTISALATE; OCTOCRYLENE; OXYBENZONE; AVOBENZONE; HOMOSALATE
Quick answers for NDC 57627-204-01
  • 11-digit billing NDC: 57627020401
Why two NDCs? The FDA registers this code as 57627-204-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 57627-0204-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

This is a topical cream formulated as an over-the-counter sunscreen under FDA's monograph rules. It contains five UV-filtering ingredients (avobenzone, homosalate, octisalate, octocrylene, and oxybenzone) that are typically used together to absorb and scatter ultraviolet light. Products of this type are commonly applied to the skin to help protect against sun exposure. The cream also includes other ingredients marketed as part of an anti-aging complex, though those supporting ingredients are not active pharmaceutical components.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
57627-0204-01 57627-204-01 You're viewing this 31 g in 1 BOTTLE, PUMP (57627-204-01) 2021-11-29 Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Anti-Aging Complex Broad Spectrum Spf 30 4 g/100g; 2.35 g/100g; 5 g/100g; 3 g/100g; 8 g/100gthis 57627-0204-01 Merle 31 g — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2021
On the market since
Nov 2021
📍
2026
Currently FDA-listed
5 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerMerle Norman Cosmetics, Inc.
FDA applicationM020 (OTC MONOGRAPH DRUG)
Labeler code57627
First marketedNov 2021
Product typeHuman Otc Drug
Portfolio8 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 9 words ▾

Stop use and ask a doctor if rush occurs.

⏱️ Dosage and Administration 113 words ▾

Directions For sunscreen use: apply liberally and evenly 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every 2 hours children under 6 months: Ask a doctor Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m. - 2 p.m. wear long-sleeved shirts, pants, hats, and sunglasses children under 6 months: Ask a doctor Apply to cleansed and toned skin prior to sun exposure.

⚠️ Warnings 26 words ▾

Warnings For external use only Do not use on damaged or broken skin When using this product keep out of eye. Rinse with water to remove.

📦 Storage and Handling 11 words ▾

Other information protect this product from excessive heat and direct sun

🧪 Active Ingredient 18 words ▾

Active ingredients Purpose Avobenzone 3.0% Sunscreen Homosalate 8.0% Sunscreen Octisalate 4.0% Sunscreen Octocrylene 2.35% Sunscreen Oxybenzone 5.0% Sunscreen

🧪 Inactive Ingredients 100 words ▾

Inactive ingredients: Aqua/Water/Eau, Glycerin, Ethoxydiglycol, Butylene Glycol, Alcohol Denat., Cyclopentasiloxane, Glycereth-26, Isostearyl Neopentanoate, Nylon-12, Glyceryl Stearate, Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate, Isononyl Isononanoate, Phenoxyethanol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polymethyl Methacrylate, Hydrolyzed Malt Extract, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Hydrogenated Lecithin, PEG-100 Stearate, Caprylyl Glycol, Mica (CI 77019), Coco-Glucoside, Ethylhexylglycerin, Tetrasodium EDTA, Xanthan Gum, Coconut Alcohol, BHT, Bisabolol, Hexylene Glycol, Propylene Glycol, Caprylyl/Capryl Glucoside, Opuntia Ficus-Indica Stem Extract, Hydroxypropyl Cyclodextrin, Acetyl Tyrosine, Phospholipids, Panax Ginseng Root Extract, Camellia Sinensis Leaf Extract, Proline, Silica, Adenosine Triphosphate, Hydrolyzed Vegetable Protein, Acetyl Octapeptide-3, Equisetum Arvense Extract, Acetylarginyltryptophyl Diphenylglycine, Ascorbyl Palmitate, Retinyl Palmitate, Palmitoyl Tripeptide-38, Tocopheryl Acetate.

🎯 Purpose 29 words ▾

Uses helps prevent sunburn If used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging by the sun

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 57627-204-01, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 57627-0204-01, written without dashes as 57627020401. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 57627-0204-01, the first segment (57627) is the labeler code FDA assigned to Merle Norman Cosmetics, Inc.; the middle segment (0204) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Merle Norman Cosmetics, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Merle Norman Cosmetics, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 57627-0203-01 · Merle 57627-0205-02 · Merle →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.