VITAL PERFECTION UPLIFTING AND FIRMING ADVANCED DAY Avobenzone, Homosalate, Octinoxate, Octocrylene 3.53 g/50mL; 1.28 g/50mL; 2.56 g/50mL; 1.54 g/50mL Cream, 50 mL
🆔 Identity & classification
Where does this data come from?
🏭 Manufacturer & labeler
Where does this data come from?
🩺 Clinical
Vital Perfection Uplifting and Firming Advanced Day is an over-the-counter topical cream marketed under FDA's monograph rules for sunscreen products. It contains four ultraviolet (UV) light filters: avobenzone, homosalate, octinoxate, and octocrylene. These ingredients are typically used together to absorb and scatter UV radiation from the sun. Products of this type are commonly applied to the skin to help reduce sun exposure.
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Supplement & herbal interactions
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💊 What it looks like
Where does this data come from?
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII 9E8X80D2L0
A synthetic form of vitamin E used as an antioxidant and preservative in medications. It helps prevent the active ingredients from degrading when exposed to oxygen or light.
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UNII 3K9958V90M
A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
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UNII ICT8SQC61W
A fragrant oil extracted from alpinia speciosa plant leaves. Used primarily as a flavoring and fragrance ingredient to improve the taste and aroma of oral medicines.
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UNII 40RUH3S7RZ
A plant extract from Angelica keiskei, a species native to East Asia. It functions as a flavoring agent and natural colorant in medicines, contributing taste and appearance to the formulation.
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UNII 39YR661C4U
A synthetic chemical compound used as a preservative in medicines to prevent bacterial and fungal growth, helping keep the product safe and effective during storage.
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UNII BJ4GP2IFLN
Beheneth-20 is a surfactant derived from behenic acid, a fatty acid. It helps mix oil and water-based ingredients together in formulations and can act as an emulsifier or solubilizer.
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Docosanol is a waxy, fatty alcohol derived from plant sources. It acts as an emollient and thickener in topical medicines, helping to soften the skin and improve product texture and stability.
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UNII X04E310LUY
Bupleurum falcatum root is a plant extract used as a natural flavoring and botanical ingredient. It may help mask bitter tastes and add herbal characteristics to the medicine.
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UNII 1P9D0Z171K
BHT is a synthetic antioxidant that prevents fats and oils in medicines from breaking down and becoming rancid. It helps keep the product stable and effective during storage.
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UNII 3XUS85K0RA
Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
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UNII A9EJ3J61HQ
A synthetic liquid derived from benzoic acid and long-chain alcohols. It functions as a solvent and penetration enhancer in topical formulations, helping active ingredients dissolve and absorb into the skin.
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UNII 3G6A5W338E
Caffeine is a natural stimulant compound commonly extracted from coffee beans and tea leaves. In medicines, it serves as an active booster in pain relievers and cold products to enhance alertness and improve the effectiveness of other ingredients.
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A plant extract from green tea leaves. It's used as an antioxidant ingredient to help preserve the medicine and maintain its stability during storage.
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A silicone-based ingredient that acts as a lubricant and glidant. It helps the tablet or capsule move smoothly through manufacturing equipment and improves powder flow during production.
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Safflower is a plant-derived ingredient used as a natural colorant and flavoring agent in medicines. It may also serve as a filler to add bulk to the formulation.
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UNII 2968PHW8QP
A weak organic acid derived from citrus fruits or made through fermentation. It works as a buffer to control pH, a preservative to extend shelf life, and a flavoring agent in medications.
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A plant extract from hawthorn flowers used as a natural flavoring agent and coloring ingredient in medicines. It may also help bind ingredients together in tablet or capsule formulations.
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Diglycerin is a humectant and solvent derived from glycerin. It helps retain moisture in the formulation and improves texture and stability in liquid or semi-solid medicines.
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UNII 92RU3N3Y1O
Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
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UNII E107L85C40
Dipropylene glycol is a clear liquid made from propylene glycol. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
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Erythritol is a sugar alcohol derived from fermented fruits or grains. It's used as a sweetener and bulking agent in medicines to improve taste without adding significant calories.
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UNII 1K09F3G675
Ferric oxide red is an inorganic iron compound used as a colorant in medicines. It gives tablets, capsules, or other dosage forms a red or reddish tint for identification and appearance.
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Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
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Inositol is a naturally occurring sugar-like compound. It acts as an osmotic agent and sweetener in medications, helping draw water into the formulation and improve taste.
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Isododecane is a lightweight liquid hydrocarbon used as a solvent and spreadability agent in topical formulations. It helps dissolve active ingredients and makes the product easier to apply and absorb into the skin.
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Lamium album whole is a plant-derived ingredient used as a natural coloring, flavoring, or traditional botanical component in some formulations. It may help provide color, taste, or texture to the finished medicine.
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A fragrant oil extracted from lavender plants, used as a flavoring and scent agent in medicines to improve taste and aroma.
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Panax ginseng root is a plant extract traditionally used in herbal preparations. In medications, it may serve as an active botanical ingredient or be included for flavoring and as a natural preservative or binder in formulations.
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UNII 4ET18WJG5K
A synthetic liquid polymer made from ethylene glycol and propylene glycol components. Used in medications as a solvent to dissolve active ingredients and improve how the medicine flows and mixes in liquid formulations.
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Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
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A plant-derived oil compound used as an emollient and skin-conditioning agent. It helps soften the product texture and improve how the medicine spreads on or absorbs into the skin.
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A synthetic compound that belongs to the salicylate family of chemicals. It serves as a preservative and antimicrobial agent in topical formulations to help prevent bacterial and fungal growth and extend product shelf life.
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A plant extract from damask rose flowers used as a natural fragrance, flavoring agent, or coloring component in medicines. It adds pleasant aroma or taste to the product.
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A plant extract from rosemary flowers used as a natural preservative and antioxidant. It helps prevent oils and fats in the medicine from spoiling, keeping the product fresh during storage.
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Shea butter is a fat extracted from shea tree nuts. It's used in medicines as an emollient and lubricant to soften the product, improve texture, and help ingredients blend smoothly together.
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Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
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Sodium citrate is a salt derived from citric acid. It works as a buffer to maintain the medicine's pH level and may also help improve taste or act as a preservative in the formulation.
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Sodium metabisulfite is a preservative derived from sulfur compounds. It prevents microbial growth and oxidation in medicines, helping extend shelf life and maintain product stability.
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A salt derived from phosphoric acid, sodium metaphosphate acts as a buffer and sequestrant in medicines. It helps stabilize the product and prevent unwanted chemical reactions during storage.
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Stearyl alcohol is a waxy, fatty substance derived from natural oils or made synthetically. It acts as an emulsifier and thickener in medicines, helping mix ingredients together and give the product the right texture.
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A natural polysaccharide (complex sugar) produced by bacteria. It acts as a thickener, binder, and stabilizer to improve texture and help keep medicine ingredients evenly mixed in the formulation.
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UNII R0ZB2556P8
Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
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UNII B8WCK70T7I
Trehalose is a natural sugar made from two glucose molecules linked together. It's used in medicines as a filler to add bulk, a sweetener for taste, and a stabilizer to help keep active ingredients effective during storage.
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UNII 420IP921MB
A chelating agent derived from edetic acid that binds to metals in the formulation. It helps stabilize the medicine by preventing metal ions from causing breakdown or discoloration.
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Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
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Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.
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UNII AQG914O70P
A plant extract from the jujuba fruit tree, used as a natural sweetener, flavoring agent, and binder in medications to improve taste and help hold the formula together.
47 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
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💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Vital Perfection Uplifting And Firming Advanced Day 3.53 g/50mL; 1.28 g/50mL; 2.56 g/50mL; 1.54 g/50mLthis 58411-0950-40 | Shiseido | 50 ml | — | — | FDA listed | — |
Where does this data come from?
⏳ Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 58411-0950-40 You're viewing this | 1 CONTAINER in 1 BOX (58411-950-40) / 50 mL in 1 CONTAINER | 2025-12-09 | Active |
| 58411-0950-50 | 1 JAR in 1 BOX (58411-950-50) / 50 mL in 1 JAR | 2025-12-09 | Active |
Pack size FAQ
What quantity is in NDC 58411-0950-40?
What NDC number is used to bill for this package of VITAL PERFECTION UPLIFTING AND FIRMING ADVANCED DAY Avobenzone, Homosalate, Octinoxate, Octocrylene 3.53 g/50mL; 1.28 g/50mL; 2.56 g/50mL; 1.54 g/50mL Cream?
🧭 About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
Questions about this listing
Is this NDC FDA-approved?
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Does this product come in other package sizes?
Who lists this product with the FDA?
Do I need a prescription for this product?
Where does this data come from?
📄 FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses Helps prevent sunburn
⏱️ Dosage and Administration ▾
Directions apply liberally 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every 2 hours Sun Protection Measures. Spending time in the sun increases your risk of skin cancerr and early skin aging. To decrease this rick, regularly use a sunscreen with a Broad Spectru, SPF of 15 or higher and other sun protection measures including: • limit time in the sun, especially from 10 a.m. - 2 p.m. • wear long-sleeve shirts, pants, hats, and sunglasses Children under 6 months: Ask a doctor
⚠️ Warnings ▾
Warnings For external use only
📦 Storage and Handling ▾
Other information protect this product in this container from excessibe heat and direct sunlight
🧪 Inactive Ingredients ▾
Water・Dipropylene Glycol・Glycerin・Dimethicone・SD Alcohol 40-B・Behenyl Alcohol・Diphenylsiloxy Phenyl Trimethicone・Hydrogenated Polydecene・Beheneth-20・Silica・Isohexadecane・Stearyl Alcohol・C30-45 Alkyl Methicone・Potassium Methoxysalicylate・Xanthan Gum・Erythritol・Tocopheryl Acetate・PEG/PPG-17/4 Dimethyl Ether・Rosa Damascena Flower Water・Phytosteryl Macadamiate・Caffeine・Lavandula Angustifolia (Lavender) Oil・Angelica Keiskei Leaf/Stem Extract・Camellia Sinensis Leaf Extract・Crataegus Monogyna Flower Extract・Lamium Album Flower/Leaf/Stem Extract・Panax Ginseng Root Extract・Inositol・Carthamus Tinctorius (Safflower) Flower Extract・Ziziphus Jujuba Fruit Extract・Rosmarinus Officinalis (Rosemary) Leaf Extract・Bupleurum Falcatum Root Extract・PPG-17・C30-45 Olefin・Butylene Glycol・Beheneth-30・Polyvinyl Alcohol・Cellulose Gum・BHT・Alcohol・Sodium Metaphosphate・Trisodium EDTA・Tocopherol・PPG-3 Dipivalate・Sodium Metabisulfite・Alpinia Speciosa Leaf Extract・Phenoxyethanol・Fragrance・Iron Oxides・
🎯 Purpose ▾
Active Ingredients Purpose Avobenzone 2.5% Sunscreen Homosalate 5.0% Sunscreen Octinoxate 6.9% Sunscreen Octocrylene 3.0% Sunscreen