cle de peau BEAUTE ADVANCED PROTECTIVE DAY Avobenzone, Homosalate, Octisalate, Octocrylene 1.2975 g/50mL; 2.3874 g/50mL; 2.3175 g/50mL; 2.595 g/50mL Cream
🆔 Identity & classification
Where does this data come from?
🏭 Manufacturer & labeler
Where does this data come from?
🩺 Clinical
This is a topical cream sunscreen marketed as an OTC monograph product. It contains four active ingredients (avobenzone, homosalate, octisalate, and octocrylene) that function as ultraviolet light filters. These ingredients are typically used in sunscreen products to absorb and scatter both UVA and UVB rays from the sun. The product is intended for daily facial use as a protective day cream.
Patient education
Supplement & herbal interactions
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💊 What it looks like
Where does this data come from?
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII 9E8X80D2L0
A synthetic form of vitamin E used as an antioxidant and preservative in medications. It helps prevent the active ingredients from degrading when exposed to oxygen or light.
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UNII 3K9958V90M
A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
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UNII 39YR661C4U
A synthetic chemical compound used as a preservative in medicines to prevent bacterial and fungal growth, helping keep the product safe and effective during storage.
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UNII BJ4GP2IFLN
Beheneth-20 is a surfactant derived from behenic acid, a fatty acid. It helps mix oil and water-based ingredients together in formulations and can act as an emulsifier or solubilizer.
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UNII 9G1OE216XY
Docosanol is a waxy, fatty alcohol derived from plant sources. It acts as an emollient and thickener in topical medicines, helping to soften the skin and improve product texture and stability.
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UNII X04E310LUY
Bupleurum falcatum root is a plant extract used as a natural flavoring and botanical ingredient. It may help mask bitter tastes and add herbal characteristics to the medicine.
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UNII 1P9D0Z171K
BHT is a synthetic antioxidant that prevents fats and oils in medicines from breaking down and becoming rancid. It helps keep the product stable and effective during storage.
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UNII 3XUS85K0RA
Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
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UNII A9EJ3J61HQ
A synthetic liquid derived from benzoic acid and long-chain alcohols. It functions as a solvent and penetration enhancer in topical formulations, helping active ingredients dissolve and absorb into the skin.
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UNII Q95M2P1KJL
A silicone-based ingredient that acts as a lubricant and glidant. It helps the tablet or capsule move smoothly through manufacturing equipment and improves powder flow during production.
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UNII 2968PHW8QP
A weak organic acid derived from citrus fruits or made through fermentation. It works as a buffer to control pH, a preservative to extend shelf life, and a flavoring agent in medications.
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UNII NT52AMP29J
A plant extract from hawthorn flowers used as a natural flavoring agent and coloring ingredient in medicines. It may also help bind ingredients together in tablet or capsule formulations.
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UNII 9DBA0SBB0L
A synthetic red dye derived from coal tar used as a colorant in medicines and cosmetics. It gives tablets, capsules, and liquids their red or pink appearance for identification and visual appeal.
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UNII 3YC120743U
Diglycerin is a humectant and solvent derived from glycerin. It helps retain moisture in the formulation and improves texture and stability in liquid or semi-solid medicines.
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UNII 92RU3N3Y1O
Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
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UNII RA96B954X6
Erythritol is a sugar alcohol derived from fermented fruits or grains. It's used as a sweetener and bulking agent in medicines to improve taste without adding significant calories.
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UNII I753WB2F1M
FD&C Yellow No. 5 is a synthetic yellow colorant approved by the FDA. It is added to medicines to make pills, tablets, or liquids visually distinct and easier to identify.
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UNII 7CTH8MD549
A natural plant extract from gardenia fruit used as a colorant in medicines. It provides yellow to orange coloring and may help preserve product stability.
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UNII 19FUJ2C58T
Ginkgo biloba leaf is a plant extract used as a flavoring or coloring agent in some medicines. It may also serve as a natural ingredient to support the product's formulation.
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UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
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UNII 525G687TQW
A natural plant extract from hibiscus seeds, used as a thickener and binder in medicines. It helps create the right texture and holds ingredients together in the formulation.
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UNII 2SFZ1X3QA9
A plant extract from hydrangea serrata leaves used in supplements and medicines. It may serve as a flavor, botanical additive, or functional ingredient in formulations.
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UNII A8289P68Y2
Isododecane is a lightweight liquid hydrocarbon used as a solvent and spreadability agent in topical formulations. It helps dissolve active ingredients and makes the product easier to apply and absorb into the skin.
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UNII COV655U2CJ
A plant extract from white lily flowers used as a fragrance, flavor, or botanical ingredient in medicines. It may help mask unpleasant tastes or add natural scent to the product.
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UNII V8A1AW0880
Mica is a naturally occurring mineral that's ground into fine powder. It's used in medicines as a colorant and anti-caking agent to improve appearance and prevent clumping in tablets or powders.
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UNII FD2FMC53M1
A plant extract from the spiny restharrow root, traditionally used in herbal preparations. In medicines, it functions as a natural flavoring agent or botanical additive to support formulation characteristics.
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UNII CUQ3A77YXI
Panax ginseng root is a plant extract traditionally used in herbal preparations. In medications, it may serve as an active botanical ingredient or be included for flavoring and as a natural preservative or binder in formulations.
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UNII 4ET18WJG5K
A synthetic liquid polymer made from ethylene glycol and propylene glycol components. Used in medications as a solvent to dissolve active ingredients and improve how the medicine flows and mixes in liquid formulations.
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UNII HIE492ZZ3T
Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
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UNII 233VSF903M
A plant-derived oil compound used as an emollient and skin-conditioning agent. It helps soften the product texture and improve how the medicine spreads on or absorbs into the skin.
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UNII 5G3H7U4Y7F
A synthetic compound that belongs to the salicylate family of chemicals. It serves as a preservative and antimicrobial agent in topical formulations to help prevent bacterial and fungal growth and extend product shelf life.
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UNII 3TNW8D08V3
Rosa canina fruit, also called rosehip, is a natural plant extract used in medicines as a filler and to add nutritional content. It may also help with texture or act as a mild flavoring agent in the formulation.
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UNII CVT1AA87FF
A plant extract from Rosa roxburghii fruit (also called chestnut rose), used as a natural flavoring agent, colorant, or antioxidant in medicines to improve taste and help preserve the product.
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UNII O3TMV4903H
A plant extract from saxifraga stolonifera (creeping saxifrage), used as a natural flavoring agent or botanical additive in medicines to enhance taste or provide mild plant-based properties to the formulation.
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UNII K49155WL9Y
Shea butter is a fat extracted from shea tree nuts. It's used in medicines as an emollient and lubricant to soften the product, improve texture, and help ingredients blend smoothly together.
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UNII ETJ7Z6XBU4
Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
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UNII WN66R7GL93
A modified form of hyaluronic acid, a naturally occurring substance that holds water. Used as a thickener, lubricant, and moisture-retaining agent in formulations, especially in topical or injectable products.
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UNII 1Q73Q2JULR
Sodium citrate is a salt derived from citric acid. It works as a buffer to maintain the medicine's pH level and may also help improve taste or act as a preservative in the formulation.
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UNII 4VON5FNS3C
Sodium metabisulfite is a preservative derived from sulfur compounds. It prevents microbial growth and oxidation in medicines, helping extend shelf life and maintain product stability.
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UNII 2KR89I4H1Y
Stearyl alcohol is a waxy, fatty substance derived from natural oils or made synthetically. It acts as an emulsifier and thickener in medicines, helping mix ingredients together and give the product the right texture.
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UNII YP632MQS35
A polysaccharide (sugar-based polymer) produced by a bacterium, used as a thickener and stabilizer to give medicines a consistent texture and prevent separation of ingredients.
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UNII 15FIX9V2JP
Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
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UNII R0ZB2556P8
Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
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UNII B8WCK70T7I
Trehalose is a natural sugar made from two glucose molecules linked together. It's used in medicines as a filler to add bulk, a sweetener for taste, and a stabilizer to help keep active ingredients effective during storage.
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UNII 420IP921MB
A chelating agent derived from edetic acid that binds to metals in the formulation. It helps stabilize the medicine by preventing metal ions from causing breakdown or discoloration.
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UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
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UNII TTV12P4NEE
Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.
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UNII 728JDI7G4M
A natural extract from the fruit rind of the Sichuan pepper plant. It serves as a flavoring agent to improve taste and may provide aroma to the medicine.
48 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| cle de peau BEAUTE ADVANCED PROTECTIVE DAY 1.2975 g/50mL; 2.3874 g/50mL; 2.3175 g/50mL; 2.595 g/50mLthis 58411-0954-50 | Shiseido | 1 jar | — | — | FDA listed | — |
Where does this data come from?
⏳ Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 58411-0954-50 You're viewing this | 1 JAR in 1 BOX (58411-954-50) / 50 mL in 1 JAR | 2025-12-15 | Active |
🧭 About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
Questions about this listing
Is this NDC FDA-approved?
Why is there no price listed?
Is the NDC printed on the package the same as the 11-digit billing NDC?
What do the three segments of this NDC mean?
Is this package still being marketed?
Who lists this product with the FDA?
Do I need a prescription for this product?
Where does this data come from?
📄 FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun
⏱️ Dosage and Administration ▾
Directions For sunscreen use: apply liberally 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every 2 hours Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF of 15 or higher and other sun protection measures including: • limit time in the sun, especially from 10 a.m. - 2 p.m. • wear long-sleeves shirts, pants, hats, and sunglasses children under 6 months: Ask a doctor
⚠️ Warnings ▾
Warnings For external use only
📦 Storage and Handling ▾
Other information protect this product in this container from excessibe heat and direct sunlight
🧪 Inactive Ingredients ▾
WATER・GLYCERIN・DIPROPYLENE GLYCOL・ALCOHOL DENAT.・BUTYLENE GLYCOL・C12-15 ALKYL BENZOATE・BEHENYL ALCOHOL・DIMETHICONE・SILICA・DIGLYCERIN・ISODODECANE・STEARYL ALCOHOL・TREHALOSE・CAPRYLYL METHICONE・POTASSIUM METHOXYSALICYLATE・ERYTHRITOL・TOCOPHERYL ACETATE・PEG/PPG-17/4 DIMETHYL ETHER・PHYTOSTERYL MACADAMIATE・XANTHAN GUM・GINKGO BILOBA LEAF EXTRACT・GARDENIA FLORIDA FRUIT EXTRACT・CRATAEGUS MONOGYNA FLOWER EXTRACT・PANAX GINSENG ROOT EXTRACT・ONONIS SPINOSA ROOT EXTRACT・HYDRANGEA SERRATA LEAF EXTRACT・ROSA CANINA FRUIT EXTRACT・SAXIFRAGA SARMENTOSA EXTRACT・ZANTHOXYLUM PIPERITUM PEEL EXTRACT・HIBISCUS ESCULENTUS FRUIT EXTRACT・SODIUM ACETYLATED HYALURONATE・ROSA ROXBURGHII FRUIT EXTRACT・LILIUM CANDIDUM FLOWER EXTRACT・BUPLEURUM FALCATUM ROOT EXTRACT・BEHENETH-20・BUTYROSPERMUM PARKII (SHEA) BUTTER・BATYL ALCOHOL・ALCOHOL・SUCCINOGLYCAN・TRISODIUM EDTA・SODIUM CITRATE・BHT・CITRIC ACID・SODIUM METABISULFITE・TOCOPHEROL・MICA・PHENOXYETHANOL・FRAGRANCE・TITANIUM DIOXIDE・RED 33・YELLOW 5・
🎯 Purpose ▾
Active Ingredients Purpose Avobenzone 2.5% Sunscreen Homosalate 4.6% Sunscreen Octisalate 4.5% Sunscreen Octocrylene 5.0% Sunscreen