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Ramipril 10 mg Capsule, 500-count — NDC 65841-0658-05 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Ramipril 10 mg Capsule, 500-count — NDC 65841-658-05 (Billing 65841-0658-05)

by Zydus Lifesciences Limited · 500 CAPSULE in 1 BOTTLE

This is a package of 500 capsules of Ramipril 10 mg Capsule from Zydus Lifesciences Limited, marketed since Nov 2010 and currently FDA-listed.

NDC 65841-0658-05
🏷️ FDA NDC (as labeled) 65841-658-05 billing pads the product segment with a zero
This package
Contains500-count Pack sizes5 compare ↓
Also priced by: Part D plans $0.1473/unit — full pricing hub ↓
Product page 65841-0658-01 Also comes in: 30 capsules 65841-658-06 90 capsules 65841-658-16 100 capsules 65841-658-01 100 capsules 65841-658-30
Rx only Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 65841-658-05 alone.

Record
FDA NDC Directory package listing · Human prescription drug
Code segments
65841 labeler · 658 product · 05 package
Package marketed since
Nov 20, 2010
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 6584165805 7
FDA record last changed
Jul 24, 2026
⚠️
Other active recalls for Ramipril (different manufacturers) — 1 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · Aug 24, 2026 — Failed Impurities/Degradation Specifications: OOS result obtained for a process impurity, dicyclohexylurea (DCU). (Hikma Pharmaceuticals USA INC.) · FDA recall D-0831-2026
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 65841-658-05
Product NDC 65841-658
11-digit billing NDC 65841065805
RxCUI 198188, 198189, 261962, 845488
UNII L35JN3I7SJ
Application # ANDA078832
SPL Set ID 496b346b-ca79-4483-a950-bed9464e6a9d
Established class (EPC) Angiotensin Converting Enzyme Inhibitor
Mechanism of action Angiotensin-converting Enzyme Inhibitors
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2010-11-20
Route ORAL
Dosage form CAPSULE
Substance RAMIPRIL
TE code (Orange Book) AB · RLD · RS
Quick answers
  • RxCUI (RxNorm): 198188
Why two NDCs? The FDA registers this code as 65841-658-05 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 65841-0658-05. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Angiotensin Converting Enzyme Inhibitor class.

Pharmacologic class Angiotensin Converting Enzyme Inhibitor
Drug family (ATC) ACE inhibitors, plain, ACE inhibitors and calcium channel blockers
How it works Angiotensin-converting Enzyme Inhibitors
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📖 What it is MedlinePlus · NLM

Ramipril is used alone or in combination with other medications: to treat high blood pressure to reduce the risk of heart attack, stroke, or death in patients at risk for these problems to improve survival in patients with heart failure after a heart attack Ramipril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently. High blood pressure is a common condition and when not treated, can cause damage to the brain...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Ramipril lowers high blood pressure, which reduces your risk of stroke and heart attack. It is also used in some adults 55 or older at high cardiovascular risk, and in stable patie...
  • Swallow them whole, once or twice a day as prescribed. If swallowing is hard, you can open the capsule and mix it into applesauce, water or apple juice. Be sure to consume all of t...
  • Headache, dizziness and tiredness are the most common. A dry, persistent cough can also happen, and it goes away after stopping the drug. Tell us if the cough or dizziness bothers...
  • Get emergency help right away for swelling of your face, lips, tongue or throat, or trouble breathing. Also call your doctor for severe belly pain, yellow skin or eyes, or fainting...
📖 Read our full Ramipril guide →
1
Nutrient depletion considerations

Ramipril may be associated with lower levels of 1 nutrient — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Ramipril nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · Q2 2026 $0.1473 $73.65 / 500 capsules
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
65841-0658-01 65841-658-01 Main listing 100 CAPSULE in 1 BOTTLE 2010-11-20 — Active
65841-0658-05 You're viewing this 500 CAPSULE in 1 BOTTLE 2010-11-20 — Active
65841-0658-06 65841-658-06 30 CAPSULE in 1 BOTTLE 2010-11-20 — Active
65841-0658-16 65841-658-16 90 CAPSULE in 1 BOTTLE 2010-11-20 — Active
65841-0658-30 65841-658-30 10 BLISTER PACK in 1 CARTON / 10 CAPSULE in 1 BLISTER PACK 2010-11-20 — Active

Pack size FAQ

What quantity is in this package?
This is a 500-count package — 500 capsule in 1 bottle.
How does this package differ from NDC 65841-0658-06?
Both are Ramipril 10 mg Capsule — the drug itself is identical. This page's package is the 500-count one, while NDC 65841-0658-06 is the 30 capsules package.
What NDC number is used to bill for this package of Ramipril 10 mg Capsule?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Ramipril 10 mg 57237-0225-01 Rising 100 capsules $0.071 AB Availability likely —
Ramipril 10 mg 62135-0274-01 Chartwell 100 capsules $0.071 AB Availability likely —
Ramipril 10 mg 65862-0477-01 Aurobindo 100 capsules $0.071 AB Availability likely —
Ramipril 10 mg 68001-0431-00 BluePoint 100 capsules $0.071 AB Availability likely —
Ramipril 10 mg 68180-0591-01 Lupin 100 capsules $0.071 AB Availability likely —
Ramipril 10 mg 68382-0147-01 Zydus 100 capsules $0.071 AB Availability likely —
Ramipril 10 mg 76282-0673-01 Exelan 100 capsules $0.071 AB Availability likely —
Ramipril 10 mg 00054-0109-25 Hikma 100 capsules — AB FDA listed —
Ramipril 10 mg 50090-1120-00 A-S 30 capsules — AB FDA listed —
Ramipril 10 mg 50090-5730-00 A-S 30 capsules — AB FDA listed —
Ramipril 10 mg 50090-6829-00 A-S 90 capsules — AB FDA listed —
Ramipril 10 mg 50090-7887-00 A-S 90 capsules — AB FDA listed —
Ramipril 10 mg 51407-0709-01 GSMS, 100 capsules — AB FDA listed —
Ramipril 10 mg 51655-0346-26 Northwind 90 capsules — AB FDA listed —
Ramipril 10 mg 51655-0406-52 Northwind 30 capsules — AB FDA listed —
Ramipril 10 mg 51655-0904-26 Northwind 90 capsules — AB FDA listed —
Ramipril 10 mg 63187-0277-30 Proficient 30 capsules — AB FDA listed —
Ramipril 10 mg 63187-0816-30 Proficient 30 capsules — AB FDA listed —
Ramipril 10 mgthis 65841-0658-05 Zydus 500 capsules — AB FDA listed —
Ramipril 10 mg 68071-3971-03 NuCare 30 capsules — AB FDA listed —
Ramipril 10 mg 70518-3038-00 REMEDYREPACK 90 capsules — AB FDA listed —
Ramipril 10 mg 71205-0029-30 Proficient 30 capsules — AB FDA listed —
Ramipril 10 mg 71335-0894-01 Bryant 30 capsules — AB FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2010
On the market since
Nov 2010
📍
2026
Currently FDA-listed
16 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color White / Yellow / Orange / Red / Blue
ShapeCapsule
ImprintZA;46;10mg
Size14 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Ramipril inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 767IP0Y5NH
    A synthetic red colorant used to give medicines their color. It helps patients identify their medication and makes the product visually appealing.
  • UNII 35SW5USQ3G
    A synthetic yellow dye used to color medicines. It helps make tablets, capsules, and liquids visually distinct so patients can easily identify their medication.
  • UNII H3R47K3TBD
    FD&C Blue No. 1 is a synthetic blue dye approved for use in foods and medicines. It serves as a colorant to give the medication its distinctive appearance and help with product identification.
  • UNII XM0M87F357
    A dark iron oxide compound that gives medicines their black or dark color. It's used as a colorant in tablets and capsules to help identify the product and make it visually distinctive.
  • UNII 2G86QN327L
    Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
  • UNII O8232NY3SJ
    A plant-based carbohydrate derived from corn kernels. It acts as a filler to add bulk, a binder to hold ingredients together, and a disintegrant to help the tablet break apart in your stomach for absorption.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.

7 inactive ingredients listed in the exact product block matched to this NDC.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerZydus Lifesciences Limited
Application holderZYDUS PHARMACEUTICALS USA INC
FDA applicationANDA078832 (ANDA)
Labeler code65841
First marketedNov 2010
Product typeHuman Prescription Drug
Portfolio720 products on file

More NDCs from Zydus Lifesciences Limited labeler code 65841

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📄 Package Label / Principal Display Panel
📄 Package Label / Principal Display Panel 84 words ▾

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL NDC 65841-655-06 in bottle of 30 Capsules Ramipril Capsules, 1.25 mg R x only 30 Capsules NDC 65841-656-01 in bottle of 100 Capsules Ramipril Capsules, 2.5 mg R x only 100 Capsules NDC 65841-657-01 in bottle of 100 Capsules Ramipril Capsules, 5 mg R x only 100 Capsules NDC 65841-658-01 in bottle of 100 Capsules Ramipril Capsules, 10 mg R x only 100 Capsules Ramipril Capsules, 1.25 mg Ramipril Capsules, 2.5 mg Ramipril Capsules, 5 mg Ramipril Capsules, 10 mg

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Ramipril — the program that covers self-administered drugs. 8 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Ramipril. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$4.16M
Claims incl. refills
338.9K
Beneficiaries
282.5K
Spend / beneficiary
$14.72
Spend / claim
$12.27
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Finished prescription product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data ✓ Available
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Zydus Lifesciences Limited. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 4 other package presentations of this same product, including 30 capsules (65841-0658-06), 90 capsules (65841-0658-16), 100 capsules (65841-0658-01). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Zydus Lifesciences Limited is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 65841-0657-01 · Zydus 65841-0659-01 · Zydus →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.