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PVP Scrub Solution Povidone Iodine 7.5 mg Solution, 236-count

by McKesson Medical-Surgical Inc. · 236.6 SOLUTION in 1 BOTTLE (68599-3501-4)
NDC 68599-3501-04
🏷️ FDA NDC (as labeled) 68599-3501-4 billing pads the package segment with a zero
This package
Contains236-count Pack sizes4 compare ↓
Also comes in: 4 bottles 68599-3501-06 12 bottles 68599-3501-02 118 solutions 68599-3501-03
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 68599-3501-4
Product NDC 68599-3501
11-digit billing NDC 68599350104
RxCUI 211747
UNII 85H0HZU99M
UPC 0612479210059, 0612479281134, 0612479281127, 0612479210035
Application # M003
SPL Set ID 49db333e-36e1-1965-e054-00144ff8d46c
Established class (EPC) Antiseptic
Chemical class Iodine
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2017-03-03
Route TOPICAL
Dosage form SOLUTION
Substance POVIDONE-IODINE
Why two NDCs? The FDA registers this code as 68599-3501-4 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 68599-3501-04. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Antiseptic class.

Pharmacologic class Antiseptic
Drug family (ATC) Iodine products, Medicated dressings with antiinfectives, Medicated shampoos
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerMcKesson Medical-Surgical Inc.
FDA applicationM003 (OTC MONOGRAPH DRUG)
Labeler code68599
First marketedMar 2017
Product typeHuman Otc Drug
Portfolio16 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • Povidone-iodine is an antiseptic — it kills bacteria on the skin. You'll find it in a lot of different products: surgical scrubs, skin prep solutions and swabs used before procedur...
  • What is povidone-iodine actually used for?
  • The standard topical products are for external skin use only — keep them away from your eyes, ears, and mouth. That said, the 3M Skin and Nasal Antiseptic is specifically labeled f...
  • For first-aid use at home, you should not use povidone-iodine on a wound for more than 7 days unless a doctor or dentist tells you it's okay. If your wound isn't improving after a...
📖 Read our full Povidone-Iodine guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII M8CF2NUW66
    A synthetic oily compound used as a lubricant and glidant in tablet and capsule manufacturing. It helps ingredients flow smoothly during production and prevents sticking to equipment.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII X70SE62ZAR
    Hydroxyethyl cellulose is a plant-derived thickener made from cellulose. It's used in medicines as a binder to hold ingredients together, a thickener for gels or liquids, and sometimes as a coating agent.
  • UNII 5KV86114PT
    A chemical compound used in medicines as a pH buffer and neutralizing agent. It helps maintain the proper acidity level in liquid formulations to improve stability and make the medicine easier to take.
  • UNII 22ADO53M6F
    A mineral salt derived from phosphoric acid, used as a buffer to maintain the pH balance of the medication and help stabilize the active ingredients.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

6 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesDisodium Phosphate, Glycerin, Hydroxy Ethyl Cellulose, Monoethanolamine, N-Dodecyl Sulfate, Purified Water

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 4 bottles 12 bottles 118 solutions
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Povidone-Iodine .75 g/100mL 53329-0938-04 Medline 118 ml — — Discontinued —
Surgical Scrub Skin Cleanser 75 mg/mL 67326-0351-03 Degasa 474 ml — — FDA listed —
Antiseptic Patient Preoperative Skin Preparation and Surgical Hand Scrub 75 mg/mL 67326-0352-03 Degasa 24 bottles — — FDA listed —
Betadine Surgical Scrub .075 mg/mL 67618-0151-01 Atlantis 3780 ml — — FDA listed —
PVP Scrub Solution 7.5 mgthis 68599-3501-04 McKesson 236 solutions — — FDA listed —
Surgical Scrub Brush/Sponge With Nail Cleaner 7.5 g/100mL 84128-0001-01 Xinxiang 30 patches — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2017
On the market since
Mar 2017
📍
2026
Currently FDA-listed
9 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📊 Medicare Part D spend CMS · PART D · 2025 (Q1-Q4)

Medicare Part D (outpatient prescription) spending for Betadine (matched by generic name) — the program that covers self-administered drugs. 1 manufacturer.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Betadine. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Total Part D spend
$874.18
Claims incl. refills
38
Beneficiaries
28
Spend / beneficiary
$31.22
Spend / claim
$23.00
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for PVP Scrub Solution (this brand).

Top reported reactions

Toxic Anterior Segment Syndrome52
Visual Acuity Reduced51
Endophthalmitis50
Post Procedural Complication25
Conjunctival Oedema21
Intraocular Pressure Increased21
Parophthalmia20

Age at onset

Adult2
Elderly3

Reporter sex

537 reports
Male · 41%
Female · 59%
Unknown · 0%

Serious outcomes

Hospitalization197
Life-threatening40
Disabling26
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
68599-3501-02 12 BOTTLE in 1 CASE (68599-3501-2) / 29.57 SOLUTION in 1 BOTTLE (68599-3501-1) 2017-03-03 Active
68599-3501-06 4 BOTTLE in 1 CASE (68599-3501-6) / 15141.6 SOLUTION in 1 BOTTLE (68599-3501-5) 2017-03-03 Active
68599-3501-03 118.3 SOLUTION in 1 BOTTLE (68599-3501-3) 2026-07-02 Active
68599-3501-04 You're viewing this 236.6 SOLUTION in 1 BOTTLE (68599-3501-4) 2026-07-02 Active

Pack size FAQ

What quantity is in NDC 68599-3501-04?
NDC 68599-3501-04 is a 236-count package — 236.6 solution in 1 bottle.
What is the difference between NDC 68599-3501-04 and NDC 68599-3501-06?
Both are PVP Scrub Solution Povidone Iodine 7.5 mg Solution — the drug itself is identical. NDC 68599-3501-04 is the 236-count package, while NDC 68599-3501-06 is the 4 bottles package.
What NDC number is used to bill for this package of PVP Scrub Solution Povidone Iodine 7.5 mg Solution?
Bill NDC 68599-3501-04 — the 11-digit billing format is 68599350104. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 68599-3501-4, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 68599-3501-04, written without dashes as 68599350104. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 68599-3501-04, the first segment (68599) is the labeler code FDA assigned to McKesson Medical-Surgical Inc.; the middle segment (3501) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (04) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by McKesson Medical-Surgical Inc.. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 3 other package presentations of this same product, including 4 bottles (68599-3501-06), 12 bottles (68599-3501-02), 118 solutions (68599-3501-03). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
McKesson Medical-Surgical Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 11 words ▾

-Washing whenever a germicidal soap is required -Maximum degerming of hands

⏱️ Dosage and Administration 152 words ▾

A. For Preoperative Washing by Operating Personnel 1. Wet hands with water.

Pour about 5 cc (1 teaspoonful) of PVP Scrub Solution on the palm of the hand and spread over both hands. Without adding more water, rub the Scrub thoroughly over all areas for about five minutes. Use brush if desired.

2. Clean thoroughly under fingernails. Add a litle water and develop copious suds.

Rinse thoroughly under running water. Complete the wash by scrubbing with another 5 cc of PVP Scrub Solution in the same way. B.

For Preoperative Use on Patients After the skin area is shaved, wet it with water. Apply PVP Scrub Solution (1 cc is sufficient to cover an area of 20-30 square inches), develop lather and scrub thoroughly for about five minutes. Rinse off by aid of sterile gauze saturated with water.

The area may then be painted with PVP Scrub Solution and allowed to dry.

⚠️ Warnings 22 words ▾

For external use only Do not • heat prior to application • use on individuals who are allergic or sensitive to iodine

🧪 Active Ingredient 7 words ▾

Povidone-Iodine, 7.5% (equivalent to 1% available iodine)

🧪 Inactive Ingredients 11 words ▾

Disodium Phosphate, Glycerin, Hydroxy Ethyl Cellulose, Monoethanolamine, N-Dodecyl Sulfate, Purified Water

🎯 Purpose 1 words ▾

Antiseptic

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 68599-3500-02 · McKesson 68599-3502-02 · McKesson →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.