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COLDTAC Plus Acetaminophen, Phenylephrin Hydrochloride, Dextromethorphan Hydrobromide 325 mg; 5 mg; 15 mg; 200 mg Tablet, 100-count — NDC 69729-0143-50 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

COLDTAC Plus Acetaminophen, Phenylephrin Hydrochloride, Dextromethorphan Hydrobromide 325 mg; 5 mg; 15 mg; 200 mg Tablet, 100-count — NDC 69729-143-50 (Billing 69729-0143-50)

by OPMX LLC · 50 POUCH in 1 CARTON / 2 TABLET in 1 POUCH

This is a package of 100 tablets of COLDTAC Plus Acetaminophen, Phenylephrin Hydrochloride, Dextromethorphan Hydrobromide 325 mg; 5 mg; 15 mg; 200 mg Tablet from OPMX LLC, marketed since Jan 2018 and currently FDA-listed.

NDC 69729-0143-50
🏷️ FDA NDC (as labeled) 69729-143-50 billing pads the product segment with a zero
This package
Contains100-count Pack sizes3 compare ↓
Product page 69729-0143-06 Also comes in: 12 tablets 69729-143-06 144 tablets 69729-143-72
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Oct 8, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 69729-143-50 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
69729 labeler · 143 product · 50 package
Package marketed since
Jul 23, 2026
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Barcode (UPC)
0856828008571, 0856828008823
FDA record last changed
Oct 8, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 69729-143-50
Product NDC 69729-143
11-digit billing NDC 69729014350
RxCUI 1367204
UNII 362O9ITL9D, 04JA59TNSJ, 9D2RTI9KYH, 495W7451VQ
UPC 0856828008571, 0856828008823
Application # M012
SPL Set ID 3496866c-682f-420b-bfdb-64ecebbf70a2
Established class (EPC) Expectorant
Physiologic effect Decreased Respiratory Secretion Viscosity; Increased Respiratory Secretions
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2018-01-05
Route ORAL
Dosage form TABLET
Substance ACETAMINOPHEN; PHENYLEPHRINE HYDROCHLORIDE; DEXTROMETHORPHAN HYDROBROMIDE; GUAIFENESIN
Quick answers
  • RxCUI (RxNorm): 1367204
Why two NDCs? The FDA registers this code as 69729-143-50 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 69729-0143-50. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Anilides class.

Drug family (ATC) Anilides
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

🧪 What is this product?

Coldtac Plus is an over-the-counter oral tablet marketed under FDA's OTC monograph rules. It combines acetaminophen, a pain reliever and fever reducer, with phenylephrine hydrochloride, a decongestant typically used to relieve nasal congestion. The tablet also contains dextromethorphan hydrobromide, which is commonly used to suppress cough, and guaifenesin, an expectorant that functions to thin mucus secretions. This combination is formulated as a multi-symptom cold and cough product for oral use.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 12 tablets 144 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
69729-0143-06 69729-143-06 Main listing 6 POUCH in 1 PACKAGE / 2 TABLET in 1 POUCH 2018-01-05 — Active
69729-0143-72 69729-143-72 72 POUCH in 1 PACKAGE / 2 TABLET in 1 POUCH 2018-01-05 — Active
69729-0143-50 You're viewing this 50 POUCH in 1 CARTON / 2 TABLET in 1 POUCH 2026-07-23 — Active

Pack size FAQ

What quantity is in this package?
This is a 100-count package — 50 pouch in 1 carton / 2 tablet in 1 pouch.
How does this package differ from NDC 69729-0143-06?
Both are COLDTAC Plus Acetaminophen, Phenylephrin Hydrochloride, Dextromethorphan Hydrobromide 325 mg; 5 mg; 15 mg; 200 mg Tablet — the drug itself is identical. This page's package is the 100-count one, while NDC 69729-0143-06 is the 12 tablets package.
What NDC number is used to bill for this package of COLDTAC Plus Acetaminophen, Phenylephrin Hydrochloride, Dextromethorphan Hydrobromide 325 mg; 5 mg; 15 mg; 200 mg Tablet?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
SanaTos Multi Symptom 325 mg/1; 15 mg/1; 200 mg/1; 5 mg 55758-0361-02 Pharmadel 2 tablets — — FDA listed —
COLDTAC Plus 325 mg/1; 5 mg/1; 15 mg/1; 200 mgthis 69729-0143-50 OPMX 100 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2018
On the market since
Jan 2018
📍
2026
Currently FDA-listed
8 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color white
ShapeCapsule
ImprintA15
Size16 mm
ScoringScored — splits in 2
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 2S7830E561
    Crospovidone is a synthetic polymer derived from povidone. It acts as a disintegrant, helping the tablet or capsule break apart quickly in the stomach so the active ingredient can be absorbed.
  • UNII OP1R32D61U
    Microcrystalline cellulose is a purified form of cellulose, a natural fiber from plant sources. It acts as a binder and filler in tablets and capsules, helping hold ingredients together and give the medicine its shape and size.
  • UNII U725QWY32X
    Povidone K30 is a synthetic polymer made from petroleum. It acts as a binder to hold tablet ingredients together and as a disintegrant to help the tablet break apart in the stomach so the medicine can be absorbed.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
  • UNII O8232NY3SJ
    A plant-based carbohydrate derived from corn kernels. It acts as a filler to add bulk, a binder to hold ingredients together, and a disintegrant to help the tablet break apart in your stomach for absorption.
  • UNII 4ELV7Z65AP
    Stearic acid is a fatty acid derived from plant or animal sources. It acts as a binder and lubricant in tablets and capsules, helping them hold together and flow smoothly during manufacturing.
  • UNII 7SEV7J4R1U
    A powder made from a naturally occurring mineral. In medicines, talc works as a glidant and anti-caking agent, helping tablets and capsules flow smoothly during manufacturing and preventing clumping.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesCorn Starch, Crospovidone, Microcrystalline cellulose, Povidone k30, Silicon dioxide, Stearic acid, Talc, Water

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerOPMX LLC
FDA applicationM012 (OTC MONOGRAPH DRUG)
Labeler code69729
First marketedJan 2018
Product typeHuman Otc Drug
Portfolio87 products on file

More NDCs from OPMX LLC labeler code 69729

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 Ask a Doctor or Pharmacist Before Use If 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 77 words ▾

Uses Temporarily Relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies Relieves sinus congestion and pressure, helps decongest sinus openings and passages Restores freer breathing Helps loosen bothersome mucus, drain bronchial tubes, and make coughs more productive Suppresses cough due to minor throat and bronchial irritation associated with a cold or inhaled irritants Temporarily relieves minor aches, pains and fever associated with: headache, common cold, toothache, backache, muscular aches, menstrual cramps

⏱️ Dosage and Administration 41 words ▾

Directions: Adults and children 12 years of age and older: Take 2 tablets every 6 to 8 hours as needed, do not exceed 8 tablets in 24 hours, or as directed by a doctor. Children under 12 years, consult a doctor

⚠️ Warnings 56 words ▾

Warnings: Liver Warning: This product contains acetaminophen. Severe liver damage may occur if you take: More than 8 tablets in 24 hours With other drugs containing acetaminophen (prescription or nonprescription). Ask a doctor or pharmacist before using with other drugs if you are not sure 3 or more alcoholic drinks every day while using this product

🧪 Active Ingredient 23 words ▾

Drug Facts Active Ingredients (in each tablet) Acetaminophen USP 325mg.........................................................Pain reliever/fever reducer Guaifenesin USP 200mg..............................................................Expectorant Phenylephrine HCL USP 5mg........................................................Decongestant Dextromethorphan HBr USP 15mg................................................Antitussive

🧪 Inactive Ingredients 15 words ▾

Inactive Ingredients Corn Starch, Crospovidone, Microcrystalline cellulose, Povidone k30, Silicon dioxide, Stearic acid, Talc, Water

🎯 Purpose 8 words ▾

Purpose Pain reliever/ fever reducer Expectorant Decongestant Antitussive

📄 Do Not Use 159 words ▾

Warning: a persistent cough may be sing of a serious condition Do not: use with any other product containing acetaminophen this will provide more than the recommended dose (overdose) of acetaminophen and cold cause serious health concerns. use more than the recommended dose for more than 10 days for pain unless directed by a doctor for more than 3 days for fever unless directed by a doctor when using this product do not exceed recommended dose if you are now taking a presription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping MAOI drug.

If you do not know if your prescription drug contains an MAOI, consult a doctor or pharmacist before taking this product take this product for persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema or where cough is accompanied by excessive phlegm (mucus) unless directed by a doctor.

📄 Ask a Doctor Before Use If 28 words ▾

Ask a doctor before use if you have: heart disease, high blood pressure, thyroid disease, diabetes, difficulty in urination due to enlargement of the prostate gland, liver disease

📄 Ask a Doctor or Pharmacist Before Use If 14 words ▾

Ask a doctor or pharmacist if you are taking the blood thinning drug warfarin.

📄 When Using This Product 74 words ▾

Allergy alert: Acetaminophen may cause severe skin reactions. Symproms may include: skin reddening, blisters, rash if a skin reaction occurs, stop use and seek medical help right away.

Do not exceed recommended dosage if nervousness, dizziness, or sleeplessness occur, discontinue use consult a doctor.

Other Inforamtion: Tamper evident. Do not use if packet is torn, cut or opened Store at controlled room temperature 15° to 30°C (59° to 86°F) Avoid excessive heat and humidity

📄 Stop Use and Ask a Doctor If 69 words ▾

Stop use and ask a doctor if: symptoms do not improve, pain or fever persists or gets worse, new symptoms occur, redness or swelling is present, symptoms do not improve within 7 days or are accompanied by fever, cough persists for more than 1 week, tends to recur, or is accompanied by a fever, rash, or persistent headache. A persistent cough may be a sign of a serious condition

🤰 If Pregnant or Breast-Feeding 10 words ▾

If pregnant or breast-feeding, ask a health professional before use.

📄 Keep Out of Reach of Children 43 words ▾

KEEP OUT OF REACH OF CHILDREN In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms

📄 Questions or Comments 10 words ▾

Questions or comments? Call: 619-600-5632 (Mon-Fri 9am - 5pm EST)

📄 Package Label / Principal Display Panel 42 words ▾

COLDTAC Plus 2 Tablets in a pouch - 12 Tablets NDC 69729-143-06 BOX POUCH

COLDTAC Plus 2 Tablets in a pouch - 144 tablets NDC 69729-143-72 Coldtac Plus 144

COLDTAC Plus 2 Tablets in a pouch - 100 tablets NDC 69729-143-50 BOX100

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by OPMX LLC. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 12 tablets (69729-0143-06), 144 tablets (69729-0143-72). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
OPMX LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 69729-0141-10 · OPMX 69729-0147-40 · OPMX →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.