Home › NDC Lookup › Ingredients › Bisacodyl Suppository › 70000-0451-01
💊image loading
(from DailyMed)

Leader Gentle Laxative Bisacodyl Suppository 10 mg Suppository, 4 suppositories

by Cardinal Health, 110 dba LEADER · 1 BLISTER PACK in 1 CARTON (70000-0451-1) / 4 SUPPOSITORY in 1 BLISTER PACK (70000-0451-4)
NDC 70000-0451-01
🏷️ FDA NDC (as labeled) 70000-0451-1 billing pads the package segment with a zero
This package
Contains4 suppositories Cost per ea$0.2933 NADAC Per package$1.17 / 4 suppositories Pack sizes2 compare ↓
Also comes in: 16 suppositories 70000-0451-02
OTC Discontinued Non-controlled ⚠ Discontinued by firm
🗂️ Data synced Mar 13, 2024 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. The listing was last certified through Dec 2024. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

🆔 Identity & classification

FDA NDC (as labeled) 70000-0451-1
Product NDC 70000-0451
11-digit billing NDC 70000045101
NCPDP billing unit EA — each (per item)
Application # part334
Physiologic effect Increased Large Intestinal Motility [PE], Stimulant Laxative [EPC], Stimulation Large Intestine Fluid/Electrolyte Secretion
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH NOT FINAL
Marketing status Discontinued
FDA listing status Discontinued by firm (certified through Dec 2024)
Route RECTAL
Dosage form SUPPOSITORY
Substance BISACODYL
GCN Seq No 002944
GCN 08731
HICL code 001301
Ingredient (HICL) Bisacodyl
HIC1 code Q
Therapeutic class — broad (HIC1) Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code Q3
Therapeutic class — intermediate (HIC2) Anal-Rectal Preparations
HIC3 code Q3S
Therapeutic class — specific (HIC3) Laxatives, Local/Rectal
AHFS code 56:12.00.00
AHFS class Cathartics And Laxatives
FDB label name GENTLE LAXATIVE 10 MG SUPP
FDB brand name Gentle Laxative
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 70000-0451-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 70000-0451-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerCardinal Health, 110 dba LEADER
FDA applicationpart334 (OTC MONOGRAPH NOT FINAL)
Labeler code70000
Product typeHuman Otc Drug
Portfolio34 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name GENTLE LAXATIVE 10 MG SUPP Ingredient Bisacodyl
📖 What it is MedlinePlus · NLM

Rectal bisacodyl is used on a short-term basis to treat constipation. It also is used to empty the bowels before surgery and certain medical procedures. Bisacodyl is in a class of medications called stimulant laxatives. It works by increasing activity of the intestines to cause a bowel movement.

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • It depends on which form you're using. Oral tablets (like Dulcolax Stimulant Laxative) usually take 6 to 12 hours, so many people take them at bedtime and get results in the mornin...
  • No — it's really important not to chew, crush, or break bisacodyl tablets. They have a special protective coating that helps them reach the right part of your gut without irritatin...
  • Can I chew or crush the tablet if I have trouble swallowing?
  • Milk and antacids can break down the protective coating on bisacodyl tablets too soon, before the medicine reaches where it needs to work. This can cause stomach irritation and mak...
📖 Read our full Bisacodyl guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.293 $1.17 / 4 suppositories
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Dec 2021 Apr 2022 Sep 2022 Feb 2024 $0.338 $0.241
▲ Up 18% over the last 15 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Leader Gentle Laxative 10 mgthis 70000-0451-01 Cardinal 4 suppositories $0.293 — Discontinued —
Bisacodyl 10 mg 00574-7050-12 Padagis 12 suppositories $0.321 — Availability likely +9%
Bisacodyl 10 mg 00904-7142-12 Major 12 suppositories $0.321 — Availability likely +9%
Good Neighbor Pharmacy Gentle Laxative 10 mg/2000mg 46122-0608-51 AmerisourceBergen 40 mg $0.321 — Availability likely +9%
Bisacodyl 10 mg 57237-0327-03 Rising 30 suppositories $0.321 — Availability likely +9%
Proctozone-B 10 mg 57237-0337-03 Rising 30 suppositories $0.321 — Availability likely +9%
Bisacodyl 10 mg 70000-0573-01 Cardinal 4 suppositories $0.321 — Availability likely +9%
Foster and Thrive Gentle Laxative 10 mg/2000mg 70677-1091-01 Strategic 40 mg $0.321 — Availability likely +9%
Walgreens Gentle Laxative 10 mg 00363-0466-04 Walgreens 40 mg — — FDA listed —
Walgreens Gentle Laxative 10 mg 00363-0468-04 Walgreens 4 suppositories — — FDA listed —
Rite-Aid Gentle Laxative 10 mg 11822-4890-05 RITE 8 suppositories — — FDA listed —
Gentle Laxative Bisacodyl 10 mg 13709-0321-01 NeilMed 30 capsules — — FDA listed —
Bisacodyl Laxative 10 mg/1.8g 13709-0328-01 Neilmed 1.8 g — — FDA listed —
HEB Gentle Laxative 10 mg/2000mg 37808-0877-08 H 40 mg — — FDA listed —
Dulcolax Laxative 10 mg 41167-0210-01 Chattem, 4 suppositories — — FDA listed —
Meijer Gentle Laxative 10 mg/2000mg 41250-0665-04 Meijer 40 mg — — FDA listed —
Discount Drugmart Gentle Laxative 10 mg/2000mg 53943-0805-08 Discount 40 mg — — FDA listed —
Dollar General Gentle Laxative 10 mg/2000mg 55910-0457-04 Dolgencorp, 40 mg — — FDA listed —
Bisacodyl 10 mg 57896-0443-01 GERI-CARE 100 suppositories — — FDA listed —
Stratuscare Bisacodyl 10 mg 58980-0415-04 Stratus 4 suppositories — — FDA listed —
CVS Gentle Laxative 10 mg 59779-0107-09 CVS 8 suppositories — — FDA listed —
Bisacodyl 10 mg 68016-0084-08 Pharmacy 8 suppositories — — FDA listed —
Bisacodyl 10 mg 69842-0816-04 CVS 4 suppositories — — FDA listed —
Laxative 10 mg 70795-1010-01 GRAXCELL 100 suppositories — — FDA listed —
OneLAX 10 mg 71399-8460-02 AKRON 12 suppositories — — FDA listed —
Conlax 10 mg 72701-0102-04 Bliss 4 suppositories — — FDA listed —
Bisacodyl 10 mg 82568-0028-02 AARNA 12 suppositories — — FDA listed —
Bisacodyl 10 mg 83720-0550-25 Oncor 12 suppositories — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startStatus
70000-0451-02 4 BLISTER PACK in 1 CARTON (70000-0451-2) / 4 SUPPOSITORY in 1 BLISTER PACK (70000-0451-3) $0.2969 / ea $4.75 2019-01-23 Discontinued by firm
70000-0451-01 You're viewing this 1 BLISTER PACK in 1 CARTON (70000-0451-1) / 4 SUPPOSITORY in 1 BLISTER PACK (70000-0451-4) $0.2933 / ea $1.17 2019-01-24 Discontinued by firm

This pack has the lowest per-ea cost of the 2 priced pack sizes ($0.2933 NADAC).

Pack size FAQ

What quantity is in NDC 70000-0451-01?
NDC 70000-0451-01 contains 4 suppositories — 1 blister pack in 1 carton / 4 suppository in 1 blister pack.
What is the difference between NDC 70000-0451-01 and NDC 70000-0451-02?
Both are Leader Gentle Laxative Bisacodyl Suppository 10 mg Suppository — the drug itself is identical. NDC 70000-0451-01 is the 4 suppositories package, while NDC 70000-0451-02 is the 16 suppositories package. Per-ea NADAC also differs: $0.2933 here vs $0.2969 for the 16 suppositories pack.
What NDC number is used to bill for this package of Leader Gentle Laxative Bisacodyl Suppository 10 mg Suppository?
Bill NDC 70000-0451-01 — the 11-digit billing format is 70000045101. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) — Not published for this NDC No structured label is linked to this listing in DailyMed/openFDA.
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) ✓ Available
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Not Final". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no full label on this page?
No structured FDA label (SPL) is currently linked to this NDC in DailyMed/openFDA. That can happen with older listings, certain OTC and repackaged products, and recently updated listings whose label has not yet propagated. The listing itself is still valid — this page shows everything the public feeds provide for this package.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 70000-0451-1, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 70000-0451-01, written without dashes as 70000045101. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 70000-0451-01, the first segment (70000) is the labeler code FDA assigned to Cardinal Health, 110 dba LEADER; the middle segment (0451) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 16 suppositories (70000-0451-02). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Cardinal Health, 110 dba LEADER is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📄 FDA label
📄 FDA label 19 words ▾

No FDA label is on file for this product yet. Labels load from openFDA / DailyMed and refresh weekly.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
← 70000-0448-01 · Cardinal 70000-0456-01 · Cardinal →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.