HomeNDC LookupIngredientsMenthol, Unspecified Form › 71391-0127-05
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Menthol 5% Hydrogel MENTHOL, UNSPECIFIED FORM 600 mg Patch, 5 patches

by Unexo Life Sciences, Private Limited · 5 PATCH in 1 POUCH (71391-127-05)
NDC 71391-0127-05
🏷️ FDA NDC (as labeled) 71391-127-05 billing pads the product segment with a zero
OTC Discontinued Non-controlled ⚠ Discontinued by firm
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. The listing was last certified through Sep 2025. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

🆔 Identity & classification

FDA NDC (as labeled) 71391-127-05
Product NDC 71391-127
11-digit billing NDC 71391012705
RxCUI 420222
UNII L7T10EIP3A
Application # M017
SPL Set ID 3f6feec5-2019-4fe6-b2b9-fd1c04d9a1f1
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Discontinued by firm (certified through Sep 2025)
Marketing start 2020-10-01
Route TOPICAL
Dosage form PATCH
Substance MENTHOL, UNSPECIFIED FORM
Why two NDCs? The FDA registers this code as 71391-127-05 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 71391-0127-05. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerUnexo Life Sciences, Private Limited
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code71391
First marketedOct 2020
Product typeHuman Otc Drug
Portfolio4 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • Menthol is found in a lot of over-the-counter topical products — creams, gels, patches, sprays, and powders. Depending on the product, it's used to temporarily ease minor muscle an...
  • Start with clean, dry skin — free of lotions or creams — before applying the patch. Peel the backing off and press the sticky side firmly to the sore area. Most menthol patches sho...
  • Yes, a mild burning or tingling feeling right after applying a menthol product is common and usually settles down within a few days of regular use. What's not normal is severe burn...
  • Is that burning sensation after I apply it normal?
📖 Read our full Menthol guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

We could not link this NDC to a current FDA Structured Product Label. An inactive-ingredient list is therefore not available from this source.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Extra Strength Cold-Hot Medicated Patches 5 g 70000-0367-01 Cardinal 5 patches $0.772 FDA listed
Rugby Menthol Hot Cold Patch 5 g/100g 00536-1332-15 RUGBY 5 patches $1.008 Availability likely
Good Neighbor Pharmacy Cold Therapy Pain Relief Patch 5 g/100g 46122-0751-45 Amerisource 5 patches $1.008 Availability likely
Walgreens Cool N Heat Back Patch 50 mg/g 00363-6657-05 Walgreen 5 patches FDA listed
Walgreens Cold Therapy Pain Relieving Patch 50 mg/g 00363-6669-05 Walgreen 5 patches FDA listed
Walgreens Cool N Heat Patch XL 50 mg/g 00363-6672-03 Walgreen 3 patches FDA listed
Hot and Cold Medicated Patch 5 g/100g 00363-9520-05 Walgreen 5 pouches FDA listed
Extra Large Cool and Heat Patch 5 g/100g 00363-9905-03 Walgreen 3 pouches FDA listed
Walgreens Cold Therapy Pain Relief Patch 5 g/100g 00363-9950-05 Walgreens 5 patches FDA listed
Cold and Hot Medicated 500 mg 10742-1117-01 The 5 patches FDA listed
Cold and Hot Medicated 240 mg 10742-1118-01 The 5 patches FDA listed
WellPatch Cooling Pain Relief 50 mg 10742-8125-01 The 1 patch Discontinued
Up and Up Cold and Hot Medicated 50 mg 11673-0887-05 TARGET 1 patch Discontinued
Extra Strength Cold and Hot Menthol Patch 5 g/100g 11822-6513-01 Rite 5 patches FDA listed
Rite Aid Hot and Cold Back Patch 5 g/100g 11822-9991-03 Rite 3 patches FDA listed
Signature Care Cold and Hot Medicated 50 mg 21130-0980-01 Safeway 5 patches FDA listed
Signature Care Medicated Cold and Hot Patch 5 g/100g 21130-0987-05 Safeway 5 patches FDA listed
Kroger Hot and Cold Medicated Patch 5 g/100g 30142-0979-05 Kroger 5 pouches FDA listed
Topcare Cold and Hot Medicated 50 mg 36800-0860-05 Topco 5 patches FDA listed
Icy Hot Back and Large Areas 5 g/100g 41167-0073-08 Chattem, 10 patches FDA listed
Icy Hot Back and Large Areas 5 g/100g 41167-0083-02 Chattem, 1 patch FDA listed
Icy Hot Arm Neck Leg and Small Areas 5 g/100g 41167-0084-01 Chattem, 5 patches FDA listed
Icy Hot Back and Large Areas 5 g/100g 41167-0843-01 Chattem, 5 patches FDA listed
Icy Hot XL Back and Large Areas 5 g/100g 41167-0847-01 Chattem, 3 patches FDA listed
ICY Hot Value Pack 41167-0854-00 Chattem, 5 patches FDA listed
Meijer Small Cold-Hot Medicated Patches 5 g 41250-0522-05 Meijer 5 patches FDA listed
Meijer Large Cold-Hot Medicated Patches 5 g 41250-0834-05 Meijer 5 patches FDA listed
Equate Menthol Pain Relieving 50 mg 49035-0870-01 Wal-Mart 1 patch FDA listed
Equate Cool and Heat Extra Strength 50 mg 49035-0888-30 Wal-Mart 5 patches FDA listed
Good Sense Hot and Cold Medicated Patch 5 g/100g 50804-0124-13 GOOD 5 pouches FDA listed
Goodsense Extra Strength Cold and Hot Medicated 50 mg 50804-0126-05 Geiss, 5 patches FDA listed
CVS Cooling Patch .5 g/10g 51316-0796-02 CVS 2 patches FDA listed
CVS Health Cooling Patch 5 g/100g 51316-0976-10 CVS 10 patches FDA listed
Cold And Hot Medicated Large .05 g/g 52000-0421-41 Universal 1 patch FDA listed
Cold And Hot Medicated .05 g/g 52000-0422-41 Universal 2 patches FDA listed
Medline 5 mg/100mg 53329-0972-05 Medline 5 patches FDA listed
Menthol Pain Relief Gel Patch 50 mg 55629-0025-15 ONE2ZEE 15 patches FDA listed
Dollar General Cold-Hot Medicated Patches 5 g/100g 55910-0903-01 DOLGENCORP, 1 pouch FDA listed
Dollar General Cold Therapy Pain Relief 5 g/100g 55910-0949-01 Dolgencorp, 1 g FDA listed
Dollar General Cold-Hot Medicated Patches 5 g 55910-0972-06 DOLGENCORP, 6 patches FDA listed
Biofreeze Overnight Relief .3 g/6g 59316-0005-03 Reckitt 1 patch FDA listed
Biofreeze Day and Overnight 59316-0832-94 Reckitt 1 patch FDA listed
Biofreeze Menthol 59316-0887-04 Reckitt 1 patch FDA listed
Biofreeze Menthol .05 g/g 59316-0992-07 Reckitt 1 patch FDA listed
Icy Hot Medicated 205.5 mg 62168-0084-03 Lead 1350 patches Discontinued
Icy Hot Medicated, XL 750 mg 62168-0847-04 Lead 400 patches FDA listed
Icy Hot Medicated, Back 428.5 mg 62168-0853-01 Lead 500 patches FDA listed
Winco Cold and Hot Medicated Patch Large 50 mg 67091-0914-05 WINCO 5 patches FDA listed
Hot/Cold Medicated Patch 285 mg/5700mg 67777-0201-10 Dynarex 900 patches FDA listed
Absorbine Jr 5000 mg/h 69693-0412-01 Clarion 1 patch FDA listed
Icequake Coldn Hot medicated patch 50 mg/g 69822-0014-04 Southern 4 patches FDA listed
CVS Cold and Hot 50 mg 69842-0243-05 CVS 5 patches FDA listed
CVS Cold and Hot 50 mg 69842-0245-05 CVS 5 patches FDA listed
Bengay Ultra Strength Large Size 50 mg 69968-0487-01 Kenvue 1 patch Discontinued
HealthWise Medicated Cold Hot 5% Patch 5 g 71101-0031-06 Veridian 6 patches FDA listed
Cold Hot Medicated Patch 5% Menthol 5 g 71101-0060-05 Veridian 5 patches FDA listed
Cold Hot Medicated Patch 5% Menthol 5 g 71101-0061-05 Veridian 5 patches FDA listed
HealthWise Medicated Cold Hot 5% 5 g 71101-0084-15 Veridian 15 patches FDA listed
HealthWise Overnight Menthol Patch 5 g 71101-0085-12 Veridian 12 patches FDA listed
TheraCare Pain Relief 5 g/100g 71101-0126-01 Veridian 4 patches FDA listed
Thera Care Pain Relief Menthol Patchs 5 g/100g 71101-0913-05 Veridian 5 pouches FDA listed
Theracare Cold Therapy Pain Relief 5 g 71101-0949-01 Veridian 5 patches FDA listed
HealthWise Cold Therapy Pain Relief Patch 5 g/100g 71101-0950-15 Veridian 15 patches FDA listed
Hot and Cold Medicated Patch 5 g/100g 71101-0952-15 Veridian 15 pouches FDA listed
Thera Care Hot and Cold Medicated Patch 5 g/100g 71101-0953-05 Veridian 5 pouches FDA listed
Thera Care Cold Hot Medicated Patch 5 g/100g 71101-0954-05 Veridian 5 pouches FDA listed
Dr Sabharwals 240 mg 71318-0116-15 Dr. 15 patches FDA listed
Menthol 5% 440 mg 71391-0123-18 Unexo 18 patches Discontinued
Menthol 5% Hydrogel 600 mgthis 71391-0127-05 Unexo 5 patches Discontinued
Cold Hot Medicated Patch 5% Menthol 5 g 71811-0005-05 InterMed 5 patches FDA listed
Cold Hot Medicated Patch 5% Menthol 5 g 71811-0006-05 InterMed 5 patches FDA listed
Hot and Cold Medicated Patch 5 g/100g 72036-0952-05 Harris 5 pouches FDA listed
Amazon Basics Cold and Hot Medicated Patch 5 g/100g 72288-0966-15 Amazon.com 15 patches FDA listed
Cycle 5 g/100g 72587-0001-02 La 1 patch FDA listed
Relief 5 g/100g 72587-0003-01 La 4 patches FDA listed
Hempvana Cold As Ice Pain Relief Gel-Patch 5 g/100g 73287-0005-01 Telebrands 7 patches FDA listed
MENTHOL PAIN RELIEF Gel-Patch .05 g/g 73557-0131-15 Shanghai 15 patches Discontinued
OVERNIGHT RELIEF Gel-Patch .05 g/g 73557-0133-05 Shanghai 5 patches FDA listed
Pain Relief .05 g/g 73557-0192-05 Shanghai 5 patches FDA listed
BonicaEaseX 24 Hour Menthol Pain Relieving 50 mg/g 75568-0045-00 Planet 15 patches FDA listed
Topcare Pain Relief Patch 5 g/100g 76162-0999-05 76162 5 patches FDA listed
Meijer Cold Therapy Pain Relieving 5 g/100g 79481-9966-05 Meijer 1 g FDA listed
Menthol 5% 500 mg/10g 80425-0543-01 Advanced 30 patches FDA listed
Cold Hot Medicated Patch 5% Menthol 5 g 83324-0256-05 Quality 5 patches FDA listed
Hot Cold Medicated Patches 5 g/1001 83559-0003-01 Henan 2 patches FDA listed
COLD AND HOT MEDICATED Patch 5 g/1001 83559-0014-01 Henan 48 patches FDA listed
COLD AND HOT MEDICATED Patch 5 g/1001 83559-0015-01 Henan 24 patches FDA listed
Rapid Relief 5 g/100g 83569-0012-05 RAPID 1 pouch FDA listed
Menthol Pain Relief Gel-Patch .05 g/g 83602-0132-15 Guangzhou 15 patches FDA listed
COLD HOT CHINESE RED TIGER PAIN RELIEF GeI-Patch .05 g/g 84165-0004-01 Guangzhou 12 g FDA listed
AVCOO Menthol Pain Relief Patch 500 mg 84992-0004-01 ADP 1 patch FDA listed
Menthol 5% 500 mg/10g 85096-0301-30 Marcella 30 patches FDA listed
5% Menthol Pain Relief Patch 5 g/100g 85323-0004-00 Xuzhou 5 patches FDA listed
5% Menthol Pain Relief Patch 5 g/100g 85323-0006-01 Xuzhou 48 patches FDA listed
5% Menthol Pain Relief Patch 5 g/100g 85323-0007-01 Xuzhou 24 patches FDA listed
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2020
On the market since
Oct 2020
📍
2026
Currently FDA-listed
6 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
71391-0127-05 You're viewing this 5 PATCH in 1 POUCH (71391-127-05) 2020-10-01 Discontinued by firm

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 71391-127-05, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 71391-0127-05, written without dashes as 71391012705. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 71391-0127-05, the first segment (71391) is the labeler code FDA assigned to Unexo Life Sciences, Private Limited; the middle segment (0127) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (05) identifies this exact package size and type. Together they name one specific package of one specific product.
Who lists this product with the FDA?
Unexo Life Sciences, Private Limited is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage 25 words

Use For temporary relief of minor aches and pains of muscles and joints: arthritis, simple backache, bursitis, tendonitis, muscle strains, muscle sprains, bruises and cramps

⏱️ Dosage and Administration 58 words

Directions Adults and children 12 years of age and over: Carefully remove backing from patch. Applu sticky side of patch to affected area. Wear one patch up to 8 hours. Repeat as necessary, but no more than 3 times daily. Discard patch after single use. Reseal pouch after opening. Children under 12 years of age consult a physician.

⚠️ Warnings 142 words

Warnings For external use only When using this product Use only as directed Rare cases of serious burns have been reported with products of this type Don't bandage tightly or use with a heating pad Avoid contact with eyes or mucous membranes Don't apply to wounds or damaged skin Do not use at the same time as other topical analgesics Stop use and consult a doctor if Condition worsens redness is present Irritation develops Symptoms persist for more than 7 days or clear up and occur again within a few days You experience signs of skin injury such as pain, swelling, or blistering where the product was applied.

If pregnant of breastfeeding, ask a health professional before use Keep Out of Reach of Children. Do not use on infants. If swallowed, seek medical help or contact a Poison Control Centre right away.

📦 Storage and Handling 9 words

Other Information Store at room temperature below 86°F (30°C)

🧪 Active Ingredient 4 words

Active Ingredient Menthol 5%

🧪 Inactive Ingredients 30 words

Inactive Ingredients acrylates copolymer, alcohol, carboxymethylcellulose sodium, edetate Disodium, dihydroxyaluminium aminoacetate, glycerine, kaolin, methylparaben, polysorbate 80, polyvinyl alcohol, propylparaben, PVP, sodium polyacrylate, sorbitan oleate, sorbitol, tartaric Acid, titanium Dioxide, water

🎯 Purpose 3 words

Purpose Topical Analgesic

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.