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Pharbinex-DM Guaifenesin 400mg and Dextromethorphan HBr 20mg 400 mg; 20 mg Tablet, 30-count — NDC 73057-0381-04 package photo

Pharbinex-DM Guaifenesin 400mg and Dextromethorphan HBr 20mg 400 mg; 20 mg Tablet, 30-count

by Ulai Health LLC · 30 TABLET in 1 BOTTLE, PLASTIC (73057-381-04)
NDC 73057-0381-04
🏷️ FDA NDC (as labeled) 73057-381-04 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Sep 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 73057-381-04
Product NDC 73057-381
11-digit billing NDC 73057038104
RxCUI 1147685
UNII 495W7451VQ, 9D2RTI9KYH
Application # M012
SPL Set ID af80d10e-3fb2-405a-a803-1f876b8dcd10
Established class (EPC) Expectorant
Physiologic effect Decreased Respiratory Secretion Viscosity; Increased Respiratory Secretions
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2019-07-18
Route ORAL
Dosage form TABLET
Substance GUAIFENESIN; DEXTROMETHORPHAN HYDROBROMIDE
Why two NDCs? The FDA registers this code as 73057-381-04 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 73057-0381-04. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Uncompetitive N-methyl-D-aspartate Receptor Antagonist class.

Pharmacologic class Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Sigma-1 Agonist
Drug family (ATC) Other antidepressants, Opium alkaloids and derivatives
How it works Uncompetitive NMDA Receptor Antagonists, Sigma-1 Receptor Agonists
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerUlai Health LLC
FDA applicationM012 (OTC MONOGRAPH DRUG)
Labeler code73057
First marketedJul 2019
Product typeHuman Otc Drug
Portfolio18 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • The two ingredients tackle your symptoms from different angles. Guaifenesin is an expectorant — it helps thin and loosen the mucus in your chest so you can cough it up more easily....
  • What exactly does this combination do — why are two ingredients needed?
  • It depends on which antidepressant you're taking. If it's a type called an MAOI — which includes certain older antidepressants and some medications for Parkinson's disease — you sh...
  • Can I take this if I'm on an antidepressant?
📖 Read our full Dextromethorphan / Guaifenesin guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color white
ShapeCapsule
ImprintPH073
Size18 mm
ScoringScored — splits in 2
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Quality Choice Mucus Relief DM DM 20 mg/1; 400 mg 63868-0753-50 Chain 50 tablets $0.074 — FDA listed —
Sunmark Chest Congestion Relief DM DM 20 mg/1; 400 mg 49348-0728-09 Strategic 50 tablets $0.080 — Availability likely —
Rugby Chest Congestion Relief DM 20 mg/1; 400 mg 00536-1312-08 Rugby 60 tablets $0.082 — Availability likely —
Good Neighbor Pharmacy Mucus Relief DM 20 mg/1; 400 mg 24385-0026-71 AmerisourceBergen 50 tablets $0.082 — Availability likely —
Mucus Relief DM Cough 20 mg/1; 400 mg 46122-0790-61 Amerisource 50 tablets $0.082 — Availability likely —
Leader Chest Congestion Relief DM 20 mg/1; 400 mg 70000-0056-01 Cardinal 60 tablets $0.082 — Availability likely —
Mucus Relief DM Cough Maximum Strength 20 mg/1; 400 mg 70000-0278-01 Cardinal 12 tablets $0.082 — Availability likely —
Foster and Thrive Chest Congestion Relief DM DM 20 mg/1; 400 mg 70677-1055-01 Strategic 50 tablets $0.082 — Availability likely —
Quality Choice Mucus Relief DM DM 20 mg/1; 400 mg 83324-0195-50 Chain 50 tablets $0.082 — Availability likely —
Mucus Relief DM 20 mg/1; 400 mg 00363-0533-01 Walgreen 30 tablets — — FDA listed —
Refenesen Mucus Relief DM 20 mg/1; 400 mg 10956-0846-30 Reese 30 tablets — — FDA listed —
Pharbinex-Dm 400 mg/1; 20 mg 16103-0381-04 Pharbest 30 tablets — — FDA listed —
Mucus Relief Cough and Congestion DM 20 mg/1; 400 mg 17714-0150-60 Advance 60 tablets — — FDA listed —
Kroger Chest Congestion Relief DM 20 mg/1; 400 mg 30142-0472-30 THE 30 tablets — — FDA listed —
TopCare Chest Congestion and Cough Relief DM 20 mg/1; 400 mg 36800-0988-50 TOPCO 30 tablets — — FDA listed —
Mucus Relief Dm 20 mg/1; 400 mg 37835-0403-40 Bi-Mart 40 tablets — — FDA listed —
Equaline Chest Congestion Relief DM DM 20 mg/1; 400 mg 41163-0114-50 United 50 tablets — — FDA listed —
Mucus Relief Dm 20 mg/1; 400 mg 41226-0280-03 KROGER 30 tablets — — FDA listed —
Mucus Relief DM 20 mg/1; 400 mg 41250-0533-11 Meijer 60 tablets — — FDA listed —
Guaifenesin DM 400 mg/1; 20 mg 43063-0801-60 PD-Rx 60 tablets — — FDA listed —
Medique Medi-Mucus 20 mg/1; 400 mg 47682-0432-46 Unifirst 1 tablet — — FDA listed —
Mucosa Dm 400 mg/1; 20 mg 49483-0280-00 TIME 100000 tablets — — FDA listed —
Mucus Relief DM Immediate Release 20 mg/1; 400 mg 50804-0432-30 Good 30 tablets — — FDA listed —
Mucus Relief DM 20 mg/1; 400 mg 50804-0858-30 Good 30 tablets — — Discontinued —
Mucus Relief DM Cough 20 mg/1; 400 mg 50844-0633-11 L.N.K. 60 tablets — — FDA listed —
Mucosa DM 20 mg/1; 400 mg 54257-0277-01 Magno-Humphries, 50 tablets — — FDA listed —
Mucus Relief Cough and Congestion DM 20 mg/1; 400 mg 54738-0985-30 Richmond 30 tablets — — FDA listed —
Mucus Relief DM 20 mg/1; 400 mg 55301-0533-01 ARMY 10 tablets — — FDA listed —
Family Wellness Chest Congestion Relief DM DM 20 mg/1; 400 mg 55319-0890-30 Family 30 tablets — — FDA listed —
Dollar General Chest Congestion Relief DM 20 mg/1; 400 mg 55910-0272-30 Dolgencorp, 30 tablets — — FDA listed —
Chest Congestion Relief DM 20 mg/1; 400 mg 55910-0533-01 DOLGENCORP, 30 tablets — — FDA listed —
Guaifenesin and Dextromethorphan Hydrobromide 400 mg/1; 20 mg 57631-0013-10 InvaTech 26500 tablets — — FDA listed —
Mucus Relief Xpect 400 mg/1; 20 mg 63654-0342-20 Selder, 20 tablets — — FDA listed —
Always Save Chest Congestion Relief DM 20 mg/1; 400 mg 63941-0985-50 Valu 50 tablets — — FDA listed —
Marcs Chest Congestion Relief DM 20 mg/1; 400 mg 68998-0114-50 Marc 50 tablets — — FDA listed —
Mucus Relief DM Immediate Release 20 mg/1; 400 mg 69168-0432-07 Allegiant 10 tablets — — FDA listed —
CVS Chest Congestion Relief DM 20 mg/1; 400 mg 69842-0996-30 CVS 30 tablets — — FDA listed —
RIGHT REMEDIES Mucus Relief DM 20 mg/1; 400 mg 70692-0181-25 Strive 250 tablets — — FDA listed —
Mucus Relief Cough and Congestion DM 20 mg/1; 400 mg 71335-1928-01 Bryant 30 tablets — — FDA listed —
Rugby Chest Congestion Relief DM 20 mg/1; 400 mg 71335-2216-01 Bryant 30 tablets — — FDA listed —
Mucus Relief DM 20 mg/1; 400 mg 72090-0027-01 Pioneer 150 tablets — — FDA listed —
Care One Chest Congestion Relief DM 20 mg/1; 400 mg 72476-0871-50 RETAIL 50 tablets — — FDA listed —
Pharbinex-DM 400 mg/1; 20 mgthis 73057-0381-04 Ulai 30 tablets — — FDA listed —
Mucus Relief Xpect 400 mg/1; 20 mg 76095-0012-20 Midway 20 tablets — — FDA listed —
Mucus Relief DM 20 mg/1; 400 mg 76162-0008-01 TopCo 100 tablets — — FDA listed —
Mucus DM 20 mg/1; 400 mg 79481-5330-01 Meijer 60 tablets — — FDA listed —
Mucus Relief Dm 20 mg/1; 400 mg 80513-0407-09 Advanced 90 tablets — — FDA listed —
Mucus Relief DM 20 mg/1; 400 mg 84324-0035-01 NUVICARE 100 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2019
On the market since
Jul 2019
📍
2026
Currently FDA-listed
7 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
73057-0381-04 You're viewing this 30 TABLET in 1 BOTTLE, PLASTIC (73057-381-04) 2019-07-18 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 73057-381-04, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 73057-0381-04, written without dashes as 73057038104. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 73057-0381-04, the first segment (73057) is the labeler code FDA assigned to Ulai Health LLC; the middle segment (0381) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (04) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Ulai Health LLC. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Ulai Health LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 39 words ▾

Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus helps make cough more productive temporarily relieves cough due to minor throat and bronchial irritation as may occur with a common cold

⏱️ Dosage and Administration 77 words ▾

Directions take with a full glass of water this product can be administered without regard for the timing of the meals do not exceed 6 doses in 24 hours or as directed by a doctor adults and children 12 years of age and over take 1 tablet every 4 hours as needed children 6 to under 12 years of age take ½ tablet every 4 hours as needed children under 6 years of age ask a doctor

📦 Storage and Handling 15 words ▾

Other information store at 20 0 - 25 0 C (68 0 -77 0 F)

🧪 Active Ingredient 10 words ▾

Active ingredients (in each tablet) Guaifenesin 400mg Dextromethorphan HBr 20mg

🧪 Inactive Ingredients 12 words ▾

Inactive ingredients magnesium stearate, maltodextrin, microcrystalline celluclose, povidone, silicon dioxide, stearic acid

🎯 Purpose 4 words ▾

Purpose Expectorant Cough suppressant

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 73057-0379-04 · Ulai 73057-0386-08 · Ulai →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.