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Migraine Relief ACETAMINOPHEN, ASPIRIN and CAFFEINE 250 mg; 250 mg; 65 mg Tablet, 24-count — NDC 83324-0099-24 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Migraine Relief ACETAMINOPHEN, ASPIRIN and CAFFEINE 250 mg; 250 mg; 65 mg Tablet, 24-count — NDC 83324-099-24 (Billing 83324-0099-24)

by CHAIN DRUG MARKETING ASSOCIATION, INC. · 1 BOTTLE, PLASTIC in 1 CARTON / 24 TABLET in 1 BOTTLE, PLASTIC

This is a package of 24 tablets of Migraine Relief ACETAMINOPHEN, ASPIRIN and CAFFEINE 250 mg; 250 mg; 65 mg Tablet from CHAIN DRUG MARKETING ASSOCIATION, INC., marketed since May 2024 and currently FDA-listed; retail pharmacies pay about $0.0672 per tablet (NADAC). It is this product's only package size.

NDC 83324-0099-24
🏷️ FDA NDC (as labeled) 83324-099-24 billing pads the product segment with a zero
OTC Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Oct 1, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Other active recalls for Acetaminophen, Aspirin And Caffeine (different manufacturers) — 1 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class I · Jul 11, 2024 — Labeling: Missing Label - some bottles are missing the the manufacturers label that includes the drug facts information. (Aurobindo Pharma USA Inc) · FDA recall D-0641-2024
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 83324-099-24
Product NDC 83324-099
11-digit billing NDC 83324009924
RxCUI 308297
UNII 362O9ITL9D, R16CO5Y76E, 3G6A5W338E
UPC 0635515998902
Application # ANDA214039
SPL Set ID a6a07615-3108-436f-bbce-be7cb89ce456
Established class (EPC) Nonsteroidal Anti-inflammatory Drug; Platelet Aggregation Inhibitor; Central Nervous System Stimulant; Methylxanthine
Mechanism of action Cyclooxygenase Inhibitors
Physiologic effect Decreased Prostaglandin Production; Decreased Platelet Aggregation; Central Nervous System Stimulation
Chemical class Anti-Inflammatory Agents, Non-Steroidal; Xanthines
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2024-05-01
Route ORAL
Dosage form TABLET
Substance ACETAMINOPHEN; ASPIRIN; CAFFEINE

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GCN Seq No 040186
GCN 10414
HICL code 001807
Ingredient (HICL) Aspirin/Acetaminophen/Caffeine
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H3
Therapeutic class — intermediate (HIC2) Analgesics
HIC3 code H3D
Therapeutic class — specific (HIC3) Analgesic/Antipyretics, Salicylates
AHFS code 20:12.18.00
AHFS class Platelet-Aggregation Inhibitors
FDB label name QC MIGRAINE 250-250-65 MG CPLT
FDB brand name Migraine Relief
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 040186
  • GCN: 10414
  • HICL (First Databank): 001807
  • AHFS class code: 20:12.18.00
  • RxCUI (RxNorm): 308297
Why two NDCs? The FDA registers this code as 83324-099-24 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 83324-0099-24. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Platelet Aggregation Inhibitor class.

Pharmacologic class Platelet Aggregation Inhibitor, Nonsteroidal Anti-inflammatory Drug
Drug family (ATC) Other agents for local oral treatment, Platelet aggregation inhibitors excl. heparin, Salicylic acid and derivatives
How it works Cyclooxygenase Inhibitors
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

Label name QC MIGRAINE 250-250-65 MG CPLT Ingredient Aspirin/Acetaminophen/Caffeine
📗 Our plain-language guide HelloPharmacist
  • It depends on the product. Migraine-labeled versions treat migraine. Headache and extra strength versions temporarily relieve minor aches and pains from things like headache, a col...
  • Take it by mouth with a full glass of water. Follow the directions on your product, because migraine versions and extra strength versions have different daily limits. Never take mo...
  • The caffeine can make you feel nervous, irritable or unable to sleep, and sometimes your heartbeat may feel fast. Cutting back on coffee and other caffeine while you use it can hel...
  • Stop and get help right away for a skin rash or blisters, hives, facial swelling or wheezing. Also stop for vomiting blood, black or bloody stools, stomach pain that won’t go away,...
📖 Read our full Acetaminophen / Aspirin / Caffeine guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.067 $1.61 / 24 tablets
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Dec 2025 Jan 2026 Mar 2026 May 2026 $0.067 $0.064
▲ Up 4% over the last 6 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
83324-0099-24 You're viewing this Main listing 1 BOTTLE, PLASTIC in 1 CARTON / 24 TABLET in 1 BOTTLE, PLASTIC 2024-05-01 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Extra Pain Relief 250 mg/1; 250 mg/1; 65 mg 49483-0370-00 TIME 20000 tablets $0.064 — FDA listed save 5%
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 63868-0485-01 CHAIN 100 tablets $0.064 — FDA listed save 5%
good sense migraine formula 250 mg/1; 250 mg/1; 65 mg 00113-0374-62 L. 24 tablets $0.065 — Availability likely save 3%
Pain Reliever Plus 250 mg/1; 65 mg/1; 250 mg 00536-1326-01 Rugby 100 tablets $0.065 — Availability likely save 3%
good neighbor pharmacy migraine relief 250 mg/1; 250 mg/1; 65 mg 24385-0365-71 Amerisource 50 tablets $0.065 — Availability likely save 3%
Headache Relief 250 mg/1; 250 mg/1; 65 mg 46122-0690-78 Amerisource 100 tablets $0.065 — Availability likely save 3%
Acetaminophen, Aspirin and Caffeine 250 mg/1; 250 mg/1; 65 mg 57237-0348-01 Rising 100 tablets $0.065 — Availability likely save 3%
Acetaminophen, Aspirin, Caffeine 250 mg/1; 250 mg/1; 65 mg 70000-0066-01 LEADER/ 100 tablets $0.065 — Availability likely save 3%
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 70000-0146-01 Cardinal 24 tablets $0.065 — Availability likely save 3%
Leader Migraine Relief 250 mg/1; 250 mg/1; 65 mg 70000-0247-01 Cardinal 24 tablets $0.065 — Availability likely save 3%
leader migraine relief 250 mg/1; 250 mg/1; 65 mg 70000-0611-01 Cardinal 80 tablets $0.065 — Availability likely save 3%
foster and thrive migraine relief 250 mg/1; 250 mg/1; 65 mg 70677-1133-01 Strategic 50 tablets $0.065 — Availability likely save 3%
Headache Relief 250 mg/1; 250 mg/1; 65 mg 83324-0063-24 Chain 24 tablets $0.067 — Discontinued —
Migraine Relief 250 mg/1; 250 mg/1; 65 mgthis 83324-0099-24 CHAIN 24 tablets $0.067 — Availability likely —
Excedrin Extra Strength Pain Reliever 250 mg/1; 250 mg/1; 65 mg 00067-2000-02 Haleon 2 tablets — — FDA listed —
Excedrin Extra Strength Pain Reliever 250 mg/1; 250 mg/1; 65 mg 00067-2001-01 Haleon 2 tablets — — FDA listed —
Excedrin Extra Strength Headache 250 mg/1; 250 mg/1; 65 mg 00067-2002-01 Haleon 24 tablets — — FDA listed —
Excedrin Extra Strength Headache 250 mg/1; 250 mg/1; 65 mg 00067-2003-01 Haleon 100 tablets — — FDA listed —
Excedrin Extra Strength Geltabs 250 mg/1; 250 mg/1; 65 mg 00067-2021-20 Haleon 20 tablets — — FDA listed —
Excedrin Migraine Geltabs 250 mg/1; 250 mg/1; 65 mg 00067-2035-20 Haleon 20 tablets — — FDA listed —
Excedrin Migraine 250 mg/1; 250 mg/1; 65 mg 00067-2039-02 Haleon 2 tablets — — FDA listed —
Excedrin Migraine 250 mg/1; 250 mg/1; 65 mg 00067-2040-01 Haleon 2 tablets — — FDA listed —
Excedrin Migraine Relief 250 mg/1; 250 mg/1; 65 mg 00067-2042-01 Haleon 24 tablets — — FDA listed —
Excedrin Migraine 250 mg/1; 250 mg/1; 65 mg 00067-8201-03 Haleon 300 tablets — — FDA listed —
Excedrin Extra Strength Pain Reliever 250 mg/1; 250 mg/1; 65 mg 00067-8202-03 Haleon 300 tablets — — FDA listed —
Excedrin Extra Strength Pain Reliever 250 mg/1; 250 mg/1; 65 mg 00067-8203-02 Haleon 100 tablets — — FDA listed —
good sense migraine formula 250 mg/1; 250 mg/1; 65 mg 00113-1619-27 L. 80 tablets — — FDA listed —
good sense headache relief 250 mg/1; 250 mg/1; 65 mg 00113-1855-27 L. 80 tablets — — FDA listed —
migraine relief 250 mg/1; 250 mg/1; 65 mg 00363-0374-62 Walgreen 24 tablets — — Discontinued —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 00363-0586-20 Walgreens 20 tablets — — FDA listed —
Headache Relief 250 mg/1; 250 mg/1; 65 mg 00363-0770-01 WALGREENS 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 00363-0865-25 Walgreens 250 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 00363-1150-25 Walgreens 250 tablets — — FDA listed —
migraine relief 250 mg/1; 250 mg/1; 65 mg 00363-1235-60 Walgreen 20 tablets — — FDA listed —
Acetaminophen 250mg Aspirin 250mg Caffeine 65mg 250 mg/1; 250 mg/1; 65 mg 00363-1320-12 WALGREENS 120 tablets — — FDA listed —
Walgreens Headache Relief Extra Strength 65 mg/1; 250 mg/1; 250 mg 00363-6693-12 Walgreens 120 tablets — — FDA listed —
Headache Relief 250 mg/1; 65 mg/1; 250 mg 00363-7012-01 WALGREENS 100 tablets — — FDA listed —
Extra Strength Headache Relief 250 mg/1; 250 mg/1; 65 mg 00363-7214-25 WALGREENS 250 tablets — — FDA listed —
Extra Strength Headache Relief 250 mg/1; 250 mg/1; 65 mg 00363-8992-10 WALGREENS 100 tablets — — FDA listed —
Acetaminophen Aspirin Caffeine 250 mg/1; 65 mg/1; 250 mg 00363-9680-10 WALGREEN 100 tablets — — Discontinued —
Headache Relief 250 mg/1; 250 mg/1; 65 mg 11673-0070-01 TARGET 100 tablets — — FDA listed —
Up and Up Migraine Relief 250 mg/1; 250 mg/1; 65 mg 11673-0374-78 Target 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 11673-0686-20 TARGET 20 tablets — — FDA listed —
migraine relief 250 mg/1; 250 mg/1; 65 mg 11822-0374-01 Rite 100 tablets — — FDA listed —
Pain Reliever Extra Strength 250 mg/1; 250 mg/1; 65 mg 11822-1590-02 Rite 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 11822-3343-06 Rite 200 tablets — — FDA listed —
Extra Strength Pain Relief 250 mg/1; 250 mg/1; 65 mg 21130-0037-01 BETTER 100 tablets — — FDA listed —
Acetaminophen Aspirin And Caffeine 250 mg/1; 250 mg/1; 65 mg 21130-0074-07 Better 24 tablets — — FDA listed —
Signature Care Migraine Relief 250 mg/1; 250 mg/1; 65 mg 21130-0569-62 Safeway 24 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 21130-0586-20 Safeway, 20 tablets — — FDA listed —
Acetaminophen, Aspirin and Caffeine 250 mg/1; 250 mg/1; 65 mg 21130-0681-05 Safeway, 50 tablets — — FDA listed —
Sedalmex Forte 250 mg/1; 250 mg/1; 65 mg 27854-0303-01 Belmora 40 tablets — — FDA listed —
Extra Strength Headache Relief 250 mg/1; 250 mg/1; 65 mg 29485-6486-02 Lil' 50 tablets — — FDA listed —
Extra Strenght Headache Relief 250 mg/1; 65 mg/1; 250 mg 29485-6538-06 Lil' 6 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 30142-0586-20 The 20 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 30142-0625-10 The 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 30142-0865-24 The 24 tablets — — FDA listed —
migraine relief 250 mg/1; 250 mg/1; 65 mg 30142-0896-62 Kroger 24 tablets — — FDA listed —
Topcare Migraine Relief 250 mg/1; 250 mg/1; 65 mg 36800-0533-62 Topco 24 tablets — — FDA listed —
topcare migraine relief 250 mg/1; 250 mg/1; 65 mg 36800-0934-60 Topco 20 tablets — — FDA listed —
migraine formula 250 mg/1; 250 mg/1; 65 mg 37808-0374-78 H 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 37808-0586-20 H 20 tablets — — FDA listed —
Acetaminophen, Aspirin, and Caffeine 250 mg/1; 250 mg/1; 65 mg 37835-0531-01 Bi-Mart 100 tablets — — FDA listed —
Headache Relief 250 mg/1; 250 mg/1; 65 mg 41163-0334-08 United 24 tablets — — FDA listed —
Equaline migraine formula 250 mg/1; 250 mg/1; 65 mg 41163-0374-71 United 50 tablets — — FDA listed —
Headache Relief 65 mg/1; 250 mg/1; 250 mg 41226-0370-01 Kroger 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 41250-0334-08 Meijer 24 tablets — — Discontinued —
migraine formula 250 mg/1; 250 mg/1; 65 mg 41250-0374-71 Meijer 50 tablets — — FDA listed —
Care One migraine relief 250 mg/1; 250 mg/1; 65 mg 41520-0374-62 American 24 tablets — — FDA listed —
Vanquish Extra Strength 250 mg/1; 250 mg/1; 65 mg 42364-2208-01 DSE 100 tablets — — FDA listed —
migraine formula 250 mg/1; 250 mg/1; 65 mg 42507-0374-62 HyVee 24 tablets — — FDA listed —
Xpect Pain Away Extra Strength 250 mg/1; 250 mg/1; 65 mg 42961-0234-02 Cintas 100 tablets — — Discontinued —
Medique Pain Off 65 mg/1; 250 mg/1; 250 mg 47682-0238-13 Unifirst 2 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 49035-0433-06 Wal-Mart 100 tablets — — Discontinued —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 49035-0786-80 EQUATE 80 tablets — — FDA listed —
BioElectro Extra Strength Headache Relief 250 mg/1; 250 mg/1; 65 mg 50066-0630-24 Genomma 24 tablets — — FDA listed —
Excedrin Migraine 250 mg/1; 250 mg/1; 65 mg 50090-6093-00 A-S 576 tablets — — FDA listed —
Excedrin Extra Strength Headache 250 mg/1; 250 mg/1; 65 mg 50269-0158-01 JC 2 tablets — — FDA listed —
Exaprin Plus 250 mg/1; 250 mg/1; 65 mg 50332-0144-04 HART 2 tablets — — FDA listed —
Headache Relief 250 mg/1; 250 mg/1; 65 mg 50844-0258-08 L.N.K. 24 tablets — — FDA listed —
Arthriten Inflammatory Pain Formula 250 mg/1; 65 mg/1; 250 mg 52389-0237-28 Kobayashi 28 tablets — — FDA listed —
Migraine Relief 250 mg/1; 250 mg/1; 65 mg 53943-0305-03 DISCOUNT 100 tablets — — FDA listed —
Extraprin 250 mg/1; 250 mg/1; 65 mg 54257-0858-02 Magno-Humphries, 100 tablets — — FDA listed —
Headache Formula Extra Strength 250 mg/1; 250 mg/1; 65 mg 55301-0334-12 ARMY 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 55319-0511-10 Family 100 tablets — — FDA listed —
Acetaminophen, Aspirin and Caffeine 250 mg/1; 65 mg/1; 250 mg 55319-0680-10 FAMILY 100 tablets — — FDA listed —
Migraine Relief 250 mg/1; 250 mg/1; 65 mg 55319-0970-10 Family 100 tablets — — FDA listed —
Dolex Forte 250 mg/1; 250 mg/1; 65 mg 55758-0509-24 Pharmadel 24 tablets — — FDA listed —
Headache Relief 250 mg/1; 250 mg/1; 65 mg 55910-0345-08 DOLGENCORP, 24 tablets — — FDA listed —
DG Health migraine relief 250 mg/1; 250 mg/1; 65 mg 55910-0374-62 Dolgencorp, 24 tablets — — FDA listed —
Extra Strength Headache Relief 250 mg/1; 250 mg/1; 65 mg 55910-0440-01 Dollar 100 tablets — — FDA listed —
dg health migraine relief 250 mg/1; 250 mg/1; 65 mg 55910-0448-27 Dolgencorp 80 tablets — — FDA listed —
dg health headache relief 250 mg/1; 250 mg/1; 65 mg 55910-0639-27 Dolgencorp 80 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 55910-0686-20 Dolgencorp, 20 tablets — — FDA listed —
Publix Super Markets Inc 250 mg/1; 250 mg/1; 65 mg 56062-0305-02 PUBLIX 50 tablets — — FDA listed —
Headache Relief 250 mg/1; 250 mg/1; 65 mg 56062-0934-12 Publix 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 57243-0159-08 Salado 24 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 57243-0334-08 Salado 24 tablets — — FDA listed —
Migraine Relief 250 mg/1; 250 mg/1; 65 mg 57344-0205-01 AAA 24 tablets — — FDA listed —
Extra Strength Pain Reliever 250 mg/1; 250 mg/1; 65 mg 57896-0216-01 Geri-Care 100 tablets — — FDA listed —
Acetaminophen Aspirin And Caffeine 250 mg/1; 250 mg/1; 65 mg 58602-0817-02 Aurohealth 8 tablets — — FDA listed —
Acetaminophen Aspirin And Caffeine 250 mg/1; 250 mg/1; 65 mg 58602-0882-21 Aurohealth 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 59726-0011-50 P 50 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 59779-0334-06 CVS 200 tablets — — Discontinued —
migraine relief 250 mg/1; 250 mg/1; 65 mg 59779-0374-62 CVS 24 tablets — — FDA listed —
Acetaminophen, Aspirin and Caffeine 250 mg/1; 250 mg/1; 65 mg 62207-0680-47 Granules 500 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 63941-0159-12 Valu 100 tablets — — FDA listed —
Headache, Circle K 250 mg/1; 250 mg/1; 65 mg 66715-5438-03 Lil' 18 tablets — — FDA listed —
Extra Strength Headache, Circle K 250 mg/1; 65 mg/1; 250 mg 66715-5506-04 Lil' 50 tablets — — FDA listed —
Headache Relief, Extra Strength 24/7 Life by 7-Eleven 250 mg/1; 250 mg/1; 65 mg 66715-5641-04 Lil' 24 tablets — — FDA listed —
Extra Strength Headache, Caseys 4good 65 mg/1; 250 mg/1; 250 mg 66715-6338-03 Lil' 6 tablets — — FDA listed —
Excedrin Extra Strength, TRAVEL BASIX 250 mg/1; 250 mg/1; 65 mg 66715-6410-02 Lil 2 tablets — — FDA listed —
Extra Strength Headache, Lil Drug Store 250 mg/1; 250 mg/1; 65 mg 66715-6438-06 Lil' 50 tablets — — FDA listed —
Excedrin Migraine, TRAVEL BASIX 250 mg/1; 250 mg/1; 65 mg 66715-6449-03 Lil' 2 tablets — — FDA listed —
Excedrin Extra Strength, CVP HEALTH 250 mg/1; 250 mg/1; 65 mg 66715-6510-02 Lil 2 tablets — — FDA listed —
Excedrin Migraine, CVP HEALTH 250 mg/1; 250 mg/1; 65 mg 66715-6549-02 Lil' 2 tablets — — FDA listed —
Extra Strength Headache 250 mg/1; 65 mg/1; 250 mg 66715-6922-04 Lil' 50 tablets — — FDA listed —
Excedrin Migraine 250 mg/1; 250 mg/1; 65 mg 66715-9749-03 Lil' 2 tablets — — FDA listed —
Excedrin Extra Strength 250 mg/1; 250 mg/1; 65 mg 66715-9810-02 Lil 2 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 67091-0112-10 WinCo 100 tablets — — FDA listed —
Excedrin Migraine 250 mg/1; 250 mg/1; 65 mg 67414-0239-02 Jones 2 tablets — — FDA listed —
Excedrin Extra Strength Pain Reliever 250 mg/1; 250 mg/1; 65 mg 67751-0119-01 Navajo 2 tablets — — FDA listed —
Handy Solutions Headache Pain Relief 65 mg/1; 250 mg/1; 250 mg 67751-0215-01 Navajo 2 tablets — — FDA listed —
Excedrin Migraine 250 mg/1; 250 mg/1; 65 mg 67751-0243-02 Navajo 2 tablets — — FDA listed —
Acetaminophen, Aspirin, Caffeine 250 mg/1; 65 mg/1; 250 mg 68071-3914-01 NuCare 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 69168-0285-24 Allegiant 24 tablets — — Discontinued —
Sedal3X 250 mg/1; 65 mg/1; 250 mg 69729-0055-40 OPMX 40 tablets — — FDA listed —
Artrifin 24 Caplets 250 mg/1; 65 mg/1; 250 mg 69729-0105-24 OPMX 24 tablets — — FDA listed —
Agrifen 250 mg/1; 65 mg/1; 250 mg 69729-0159-12 OPMX 12 tablets — — FDA listed —
Dolodol 65 mg/1; 250 mg/1; 250 mg 69729-0601-24 OPMX 24 tablets — — FDA listed —
Acetaminophen, Aspirin, Caffeine 65 mg/1; 250 mg/1; 250 mg 69842-0541-01 CVS 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 69842-0586-02 CVS 200 tablets — — FDA listed —
Acetaminophen 250mg Aspirin 250mg Caffeine 65mg 250 mg/1; 250 mg/1; 65 mg 69842-0591-20 CVS 200 tablets — — FDA listed —
Acetaminophen 250mg Aspirin 250mg Caffeine 65mg 250 mg/1; 250 mg/1; 65 mg 69842-0592-23 CVS 20 tablets — — FDA listed —
Acetaminophen Aspirin Caffeine 250 mg/1; 65 mg/1; 250 mg 69842-0680-10 CVS 100 tablets — — FDA listed —
Excedrin Extra Strength Headache 250 mg/1; 250 mg/1; 65 mg 70264-0045-01 R 2 tablets — — FDA listed —
EXTRA STRENGTH Headache Relief geltabs 250 mg/1; 250 mg/1; 65 mg 70692-0132-20 Strive 200 tablets — — FDA listed —
Headache Relief 250 mg/1; 250 mg/1; 65 mg 70692-0142-31 Strive 300 tablets — — FDA listed —
Acetaminophen, Aspirin and Caffeine 250 mg/1; 250 mg/1; 65 mg 71309-0079-03 Safrel 300 tablets — — FDA listed —
Pamprin Max Menstrual Pain Relief 250 mg/1; 250 mg/1; 65 mg 71687-3006-06 Focus 24 tablets — — FDA listed —
Migraine Relief 250 mg/1; 250 mg/1; 65 mg 72036-0305-03 HARRIS 100 tablets — — FDA listed —
GenCare Headache Relief 65 mg/1; 250 mg/1; 250 mg 72090-0007-02 Pioneer 300 tablets — — FDA listed —
GenCare Headache Relief 250 mg/1; 250 mg/1; 65 mg 72090-0033-01 Pioneer 300 tablets — — Discontinued —
basic care headache relief 250 mg/1; 250 mg/1; 65 mg 72288-0252-27 Amazon.com 80 tablets — — FDA listed —
basic care migraine relief 250 mg/1; 250 mg/1; 65 mg 72288-0295-27 Amazon.com 80 tablets — — FDA listed —
basic care migraine relief 250 mg/1; 250 mg/1; 65 mg 72288-0374-82 Amazon.com 200 tablets — — FDA listed —
Amazon Basic Care Migraine Relief 250 mg/1; 250 mg/1; 65 mg 72288-0376-20 Amazon.com 200 tablets — — FDA listed —
TopCare EXTRA STRENGTH Headache Relief 250 mg/1; 250 mg/1; 65 mg 76162-0142-01 Topco 100 tablets — — FDA listed —
Migraine Formula 250 mg/1; 250 mg/1; 65 mg 79481-0211-00 Meijer, 80 tablets — — FDA listed —
Extra Strength Headache Relief 250 mg/1; 250 mg/1; 65 mg 79903-0044-20 WAL-MART 200 tablets — — FDA listed —
Acetaminophen Aspirin And Caffeine 250 mg/1; 250 mg/1; 65 mg 79903-0216-10 WALMART 100 tablets — — FDA listed —
Headache Relief 250 mg/1; 65 mg/1; 250 mg 79903-0370-20 Walmart 200 tablets — — FDA listed —
Extra Strength Headache Relief 250 mg/1; 250 mg/1; 65 mg 80513-0362-15 Advanced 150 tablets — — FDA listed —
Migraine Relief 250 mg/1; 250 mg/1; 65 mg 81522-0205-03 FSA 100 tablets — — FDA listed —
ValuMeds Extra Strength Headache Relief 250 mg/1; 250 mg/1; 65 mg 82725-1023-01 Cabinet 300 tablets — — FDA listed —
good sense migraine formula 250 mg/1; 250 mg/1; 65 mg 82804-0002-30 Proficient 30 tablets — — FDA listed —
Acetaminophen, Aspirin, Caffeine 250 mg/1; 65 mg/1; 250 mg 82804-0008-30 Proficient 30 tablets — — FDA listed —
Extra Strength Pain Reliever 250 mg/1; 250 mg/1; 65 mg 82804-0163-60 Proficient 60 tablets — — FDA listed —
Headache Relief 250 mg/1; 250 mg/1; 65 mg 83324-0331-01 Chain 100 tablets — — FDA listed —
Nuvicare Headache Relief 65 mg/1; 250 mg/1; 250 mg 84324-0007-01 NUVICARE 100 tablets — — FDA listed —
Excedrin Extra Strength Headache 250 mg/1; 250 mg/1; 65 mg 85237-1868-01 Select 2 tablets — — FDA listed —
Excedrin Migraine 250 mg/1; 250 mg/1; 65 mg 85237-1871-01 Select 2 tablets — — FDA listed —
Medique Pain Off 65 mg/1; 250 mg/1; 250 mg 85766-0173-01 Sportpharm 2 tablets — — FDA listed —
good sense migraine formula 250 mg/1; 250 mg/1; 65 mg 85766-0180-01 Sportpharm 100 tablets — — FDA listed —
Dr Simi Extra Strength Acetaminophen 250 mg, Aspirin 250 mg, and Caffeine 65 mg 250 mg/1; 250 mg/1; 65 mg 85786-0105-90 Farmacias 100 tablets — — FDA listed —
Headache Relief Extra Strength 250 mg/1; 250 mg/1; 65 mg 85828-0285-93 Grocery 24 tablets — — FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2024
On the market since
May 2024
📍
2026
Currently FDA-listed
2 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color white
ShapeCapsule
ImprintI1
Size17 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII R12CBM0EIZ
    A natural wax derived from a Brazilian palm tree, used as a coating and polish on tablets and capsules. It creates a smooth, shiny finish that protects the medicine and improves appearance.
  • UNII OP1R32D61U
    Microcrystalline cellulose is a purified form of cellulose, a natural fiber from plant sources. It acts as a binder and filler in tablets and capsules, helping hold ingredients together and give the medicine its shape and size.
  • UNII 5Y0974F5PW
    Hydroxypropyl cellulose is a plant-derived thickener and binder made by chemically treating cellulose. In medicines, it helps hold tablets together, thickens liquids, and can form a protective coating on capsules.
  • UNII 0WZ8WG20P6
    Hypromellose 2910 is a plant-based cellulose derivative that acts as a thickener, binder, and film-coating agent. It helps control how quickly the medicine dissolves and protects the tablet or capsule from moisture and light.
  • UNII B697894SGQ
    Polyethylene glycol 400 is a clear, thick liquid made from petroleum-derived polymers. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
  • UNII 7CV7WJK4UI
    Sodium stearyl fumarate is a synthetic compound made from stearyl alcohol and fumaric acid. It acts as a lubricant and glidant in tablets and capsules, helping ingredients flow smoothly during manufacturing and preventing sticking.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.

7 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescarnauba wax, hydroxypropyl cellulose, hypromellose, microcrystalline cellulose, polyethylene glycol, sodium stearyl fumarate, titanium dioxide

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerCHAIN DRUG MARKETING ASSOCIATION, INC.
Application holderGRANULES INDIA LTD
FDA applicationANDA214039 (ANDA)
Labeler code83324
First marketedMay 2024
Product typeHuman Otc Drug
Portfolio122 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Very long sections are excerpted here and marked; the full text is on DailyMed (linked in the sources below). Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 Ask a Doctor or Pharmacist Before Use If 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 4 words ▾

Use ■ treats migraine

⏱️ Dosage and Administration 52 words ▾

Directions ■ do not use more than directed ■ adults: take 2 caplets with a glass of water ■ if symptoms persist or worsen, ask your doctor ■ do not take more than 2 caplets in 24 hours, unless directed by a doctor ■ under 18 years of age: ask a doctor

⚠️ Warnings ~3 min read ▾

Warnings Reye's syndrome Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert Acetaminophen may cause severe skin reactions.

Symptoms may include: ■ skin reddening ■ blisters ■ rash If a skin reaction occurs, stop use and seek medical help right away. Allergy alert Aspirin may cause a severe allergic reaction which may include: ■ hives ■ facial swelling ■ asthma (wheezing) ■ shock Liver warning This product contains acetaminophen. Severe liver damage may occur if you take ■ more than 2 caplets in 24 hours, which is the maximum daily amount ■ with other drugs containing acetaminophen ■ 3 or more alcoholic drinks every day while using this product Stomach bleeding warning This product contains an NSAID, which may cause severe stomach bleeding.

The chance is higher if you ■ are age 60 or older ■ have had stomach ulcers or bleeding problems ■ take a blood thinning (anticoagulant) or steroid drug ■ take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) ■ have 3 or more alcoholic drinks every day while using this product ■ take more or for a longer time than directed Medication overuse headache warning Headaches may worsen if this product is used for 10 or more days per month. Caffeine warning The recommended dose of this product contains about as much caffeine as a cup of coffee.

Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heartbeat. Do not use ■ if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer ■ with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist Ask a doctor before use if ■ you have never had migraines diagnosed by a health professional ■ you have a headache that is different from your usual migraines ■ you have the worst headache of your life ■ you have fever and stiff neck ■ you have headaches beginning after or caused by head injury, exertion, coughing or bending ■ you experienced your first headache after the age of 50 ■ you have daily headaches ■ you have a migraine so severe as to require bed rest ■ you have liver disease ■ stomach bleeding warning applies to you ■ you have a history of stomach problems, such as heartburn ■ you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ■ you are taking a diuretic ■ you have asthma ■ you have problems or serious side effects from taking pain relievers or fever reducers ■ you have vomiting with your migraine headache Ask a doctor or pharmacist before use if you are ■ taking a prescription drug for: ■ diabetes ■ gout ■ arthritis ■ under a doctor’s care for any serious condition ■ taking any other drug ■ taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer Stop use and ask a doctor if ■ an allergic reaction occurs.

Seek medical help right away. ■ you experience any of the following signs of stomach bleeding: ■ feel faint ■ vomit blood ■ have bloody or black stools ■ have stomach pain that does not get better ■ your migraine is not relieved or worsens after first dose ■ new or unexpected symptoms occur ■ ringing in the ears or loss of hearing occurs If pregnant or breast-feeding , ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children. In case of overd… [Excerpted — this section continues on DailyMed.]

📦 Storage and Handling 34 words ▾

Other information ■ store at controlled room temperature 20º to 25ºC (68º to 77ºF) ■ close cap tightly after use ■ read all product information before using. ■ keep this box for important information

🧪 Active Ingredient 23 words ▾

Active ingredient(s) Acetaminophen 250 mg Aspirin 250 mg (NSAID*) Caffeine 65 mg *nonsteroidal anti-inflammatory drug Purpose Pain reliever Pain reliever Pain reliver aid

🧪 Inactive Ingredients 16 words ▾

Inactive ingredients carnauba wax, hydroxypropyl cellulose, hypromellose, microcrystalline cellulose, polyethylene glycol, sodium stearyl fumarate, titanium dioxide

🎯 Purpose 8 words ▾

Purpose Pain reliever Pain reliever Pain reliver aid

📄 Do Not Use 46 words ▾

Do not use ■ if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer ■ with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist

📄 Ask a Doctor Before Use If 157 words ▾

Ask a doctor before use if ■ you have never had migraines diagnosed by a health professional ■ you have a headache that is different from your usual migraines ■ you have the worst headache of your life ■ you have fever and stiff neck ■ you have headaches beginning after or caused by head injury, exertion, coughing or bending ■ you experienced your first headache after the age of 50 ■ you have daily headaches ■ you have a migraine so severe as to require bed rest ■ you have liver disease ■ stomach bleeding warning applies to you ■ you have a history of stomach problems, such as heartburn ■ you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ■ you are taking a diuretic ■ you have asthma ■ you have problems or serious side effects from taking pain relievers or fever reducers ■ you have vomiting with your migraine headache

📄 Ask a Doctor or Pharmacist Before Use If 51 words ▾

Ask a doctor or pharmacist before use if you are ■ taking a prescription drug for: ■ diabetes ■ gout ■ arthritis ■ under a doctor’s care for any serious condition ■ taking any other drug ■ taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer

📄 Stop Use and Ask a Doctor If 76 words ▾

Stop use and ask a doctor if ■ an allergic reaction occurs. Seek medical help right away. ■ you experience any of the following signs of stomach bleeding: ■ feel faint ■ vomit blood ■ have bloody or black stools ■ have stomach pain that does not get better ■ your migraine is not relieved or worsens after first dose ■ new or unexpected symptoms occur ■ ringing in the ears or loss of hearing occurs

🤰 If Pregnant or Breast-Feeding 48 words ▾

If pregnant or breast-feeding , ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

📄 Keep Out of Reach of Children 44 words ▾

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

📄 Package Label / Principal Display Panel 36 words ▾

PRINCIPAL DISPLAY PANEL QUALITY CHOICE® NDC 83324-099-24 †Compare to Active Ingredients in EXCEDRIN® MIGRAINE Migraine Relief Acetaminophen, Aspirin (NSAID) & Caffeine Tablets Pain Reliever, Pain Reliever Aid 24 COATED CAPLETS** (**Capsule-Shaped Tablets) Actual Size image description

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 83324-0098-24 · CHAIN 83324-0100-01 · CHAIN →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.