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Dark Spot Corrector Serum 1 g/100mL; 5 g/100mL Cream, Augmented, 100 mL — NDC 84423-073-01 (Billing 84423-0073-01)

by Guangzhou Kadiya Biotechnology Co., Ltd. · 100 mL in 1 BOTTLE, PUMP

This is a package of 100 mL of Dark Spot Corrector Serum 1 g/100mL; 5 g/100mL Cream, Augmented from Guangzhou Kadiya Biotechnology Co., Ltd., no longer marketed (first marketed Feb 2025), no longer in the FDA NDC Directory. It is this product's only package size.

NDC 84423-0073-01
🏷️ FDA NDC (as labeled) 84423-073-01 billing pads the product segment with a zero
OTC Discontinued Non-controlled ⚠ Inactivated by FDA ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 84423-073-01 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
84423 labeler · 073 product · 01 package
Package marketed since
Feb 18, 2025
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 8442307301 9
FDA record last changed
Jul 24, 2026
⚠️
Excluded from the active FDA NDC Directory. FDA inactivated this product’s listing record, so it is excluded from the active NDC Directory. The listing was last certified through Dec 2026. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 84423-073-01
Product NDC 84423-073
11-digit billing NDC 84423007301
UNII 25X51I8RD4, GAN16C9B8O
Application # M016
SPL Set ID 2e62f448-14c7-d154-e063-6294a90a9daa
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Inactivated by FDA (certified through Dec 2026)
Marketing start 2025-02-18
Route CUTANEOUS
Dosage form CREAM, AUGMENTED
Substance NIACINAMIDE; GLUTATHIONE
Why two NDCs? The FDA registers this code as 84423-073-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 84423-0073-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

This is an over-the-counter topical cream marketed as a dark spot corrector. It contains glutathione and niacinamide, ingredients commonly included in skin-care products aimed at appearance of skin discoloration and uneven tone. Glutathione is an antioxidant used in many cosmetic formulations, while niacinamide (vitamin B3) is typically included for skin conditioning. The product is regulated under the FDA's monograph system for over-the-counter skin-care drugs rather than as an individually reviewed application.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
84423-0073-01 You're viewing this Main listing 100 mL in 1 BOTTLE, PUMP 2025-02-18 — Inactivated by FDA

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Dark Spot Corrector Serum 1 g/100mL; 5 g/100mLthis 84423-0073-01 Guangzhou 100 ml — — Discontinued —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2025
On the market since
Feb 2025
📍
2026
Currently FDA-listed
1 year listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII TR046Y3K1G
    A liquid alcohol derived from petroleum or plant sources. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
  • UNII LMI26O6933
    Alumina is a white powder form of aluminum oxide. It's used as a filler to add bulk to tablets and capsules, and sometimes as a thickening or anti-caking agent in powdered formulations.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII 3XUS85K0RA
    Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
  • UNII C9H2L21V7U
    A fat derived from coconut or palm oil containing shorter fatty acid chains. It serves as a solvent and carrier to help dissolve or suspend active ingredients, improving absorption and stability in liquid formulations.
  • UNII 2DMT128M1S
    A waxy solid derived from plant or animal sources. It acts as an emulsifier to blend oil and water components, and also thickens the medicine to give it the right texture and consistency.
  • UNII 09FUA47KNA
    Cetearyl glucoside is a plant-derived surfactant made from vegetable oils and glucose. It helps oils and water mix together in creams and lotions, and can also soften and smooth the skin feel of the product.
  • UNII BYR0546TOW
    DMDM hydantoin is a preservative chemical used to prevent the growth of bacteria and fungi in medicines. It helps keep the product safe and stable throughout its shelf life.
  • UNII 7FLD91C86K
    Edetate disodium is a chemical compound that binds and removes certain metal ions. In medicines, it acts as a preservative and stabilizer by preventing metals like calcium from interfering with the product's shelf life and consistency.
  • UNII NNE56F2N14
    A synthetic compound derived from glycerin and polyethylene glycol. It acts as an emulsifier and solubilizer to help mix water and oil-based ingredients and keep them blended throughout the product's shelf life.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII MEA9KH24QG
    A synthetic polymer made from glyceryl acrylate and acrylic acid. It acts as a thickener and binder in formulations, helping control consistency and hold ingredients together in the finished product.
  • UNII 86FQE96TZ4
    A synthetic polymer, this ingredient acts as a thickener and suspending agent in liquid formulations. It helps maintain uniform consistency and keeps particles evenly distributed throughout the medicine.
  • UNII 603P14DHEB
    A synthetic antimicrobial chemical used as a preservative in topical and cosmetic formulations. It prevents bacterial and fungal growth in products to maintain stability and safety during storage and use.
  • UNII T0VRI38HB0
    A synthetic polymer made from methyl vinyl ether and maleic anhydride. It acts as a binder and film-former to hold tablet ingredients together and create a protective coating on the medicine's surface.
  • UNII RU64142H6P
    PEG-90M is a thick, waxy polyethylene glycol polymer. It acts as a binder and thickening agent, helping hold tablet or capsule ingredients together and controlling how quickly the medicine dissolves.
  • UNII XJ7052W897
    A synthetic ester derived from pentaerythritol, used primarily as an emollient and skin-conditioning agent in topical formulations. It helps soften and smooth the product's texture while improving how it spreads on skin.
  • UNII CAL22UVI4M
    A synthetic emulsifier derived from sorbitol and fatty acids. It helps mix oil and water-based ingredients together and improves the texture and stability of the medicine.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII O414PZ4LPZ
    A beta hydroxy acid derived from willow bark or synthesized chemically. In topical medicines, it acts as a keratolytic agent that helps soften and shed dead skin cells, improving penetration of active ingredients.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
  • UNII 01S2G2C1E4
    Sorbitan isostearate is an emulsifier derived from sorbitol and isostearic acid. It helps mix oil and water-based ingredients together and keeps them blended throughout the medicine's shelf life.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
  • UNII TTV12P4NEE
    Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.

24 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesAQUA，PROPYLENE GLYCOL，GLYCERETH-26，GLYCERIN，PENTAERYTHRITYL TETRAETHYLHEXANOATE， CAPRYLIC/CAPRIC TRIGLYCERIDE，TITANIUM DIOXIDE，HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE，COPOLYMER，CETEARYL ALCOHOL，XANTHAN GUM，DMDM HYDANTOIN，AROMA，CETEARYL GLUCOSIDE，SILICA，DISODIUM EDTA，ALUMINA，SORBITAN ISOSTEARATE，POLYSORBATE 60，GLYCERYL ACRYLATE/ACRYLIC ACID，COPOLYMER，PEG-90M，BUTYLENE GLYCOL，1,2-HEXANEDIOL，PVM/MA COPOLYMER，IODOPROPYNYL BUTYLCARBAMATE Used for facial whitening, moisturizing and blemish removal to maintain even and radiant skin.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerGuangzhou Kadiya Biotechnology Co., Ltd.
FDA applicationM016 (OTC MONOGRAPH DRUG)
Labeler code84423
First marketedFeb 2025
Product typeHuman Otc Drug
Portfolio27 products on file

More NDCs from Guangzhou Kadiya Biotechnology Co., Ltd. labeler code 84423

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 28 words ▾

Cleanse your skin with warm water and pat dry,apply a thin layer of our Exclusive Brightening Serum on affected areas, gently massage your skin and let it absorb.

⏱️ Dosage and Administration 29 words ▾

Cleanse your skin with warm water and pat dry apply a thin layer of our Exdlusive Brightening Serum on affected areas, gently massage your skin and let it absorb.

⚠️ Warnings 17 words ▾

Warning. 1、For external use only, avoid contact with eyes when used 2、Keep out of reach of children

🧪 Active Ingredient 4 words ▾

Active Ingredients Glutathione1% NIACINAMIDE4%

🧪 Inactive Ingredients 35 words ▾

AQUA，PROPYLENE GLYCOL，GLYCERETH-26，GLYCERIN，PENTAERYTHRITYL TETRAETHYLHEXANOATE， CAPRYLIC/CAPRIC TRIGLYCERIDE，TITANIUM DIOXIDE，HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE，COPOLYMER，CETEARYL ALCOHOL，XANTHAN GUM，DMDM HYDANTOIN，AROMA，CETEARYL GLUCOSIDE，SILICA，DISODIUM EDTA，ALUMINA，SORBITAN ISOSTEARATE，POLYSORBATE 60，GLYCERYL ACRYLATE/ACRYLIC ACID，COPOLYMER，PEG-90M，BUTYLENE GLYCOL，1,2-HEXANEDIOL，PVM/MA COPOLYMER，IODOPROPYNYL BUTYLCARBAMATE

Used for facial whitening, moisturizing and blemish removal to maintain even and radiant skin.

🎯 Purpose 14 words ▾

Used for facial whitening, moisturizing and blemish removal to maintain even and radiant skin.

📄 Keep Out of Reach of Children 7 words ▾

KEEP OUT OF REACH OF CHILDREN SECTION

📄 Package Label / Principal Display Panel 73 words ▾

Active Ingredients Glutathione1% NIACINAMIDE4% Uses： Used for facial whitening, moisturizing and blemish removal to maintain even and radiant skin. The storage method： Store sealed in a cool place and out of sunlight Warning. 1、For external use only, avoid contact with eyes when used 2、Keep out of reach of children Inactive ingredients： AQUA，PROPYLENE GLYCOL，GLYCERETH-26，GLYCERIN，PENTAERYTHRITYL TETRAETHYLHEXANOATE， CAPRYLIC/CAPRIC TRIGLYCERIDE，TITANIUM DIOXIDE，HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE，COPOLYMER，CETEARYL ALCOHOL，XANTHAN GUM，DMDM HYDANTOIN，AROMA，CETEARYL GLUCOSIDE，SILICA，DISODIUM EDTA，ALUMINA，SORBITAN ISOSTEARATE，POLYSORBATE 60，GLYCERYL ACRYLATE/ACRYLIC ACID，COPOLYMER，PEG-90M，BUTYLENE GLYCOL，1,2-HEXANEDIOL，PVM/MA COPOLYMER，IODOPROPYNYL BUTYLCARBAMATE Heisetaozhuangjinghua

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Who lists this product with the FDA?
Guangzhou Kadiya Biotechnology Co., Ltd. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 84423-0072-01 · Guangzhou 84423-0074-01 · Guangzhou →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.