Home › NDC Lookup › Ingredients › Niacinamide, Glycerin › 84601-0001-01
Atti amour Rose Anti-Aging Repair Classic Essence NIACINAMIDE, GLYCERIN 6 g/100mL; 4 g/100mL Liquid, 100 mL — NDC 84601-0001-01 package photo

Atti amour Rose Anti-Aging Repair Classic Essence NIACINAMIDE, GLYCERIN 6 g/100mL; 4 g/100mL Liquid, 100 mL

by RIVER SUNZ co.,Ltd · 100 mL in 1 BOTTLE (84601-001-01)
NDC 84601-0001-01
🏷️ FDA NDC (as labeled) 84601-001-01 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 84601-001-01
Product NDC 84601-001
11-digit billing NDC 84601000101
UNII PDC6A3C0OX, 25X51I8RD4
Application # M016
SPL Set ID 1e874ac0-a993-be9e-e063-6394a90af424
Established class (EPC) Non-Standardized Chemical Allergen
Physiologic effect Increased Histamine Release; Cell-mediated Immunity; Increased IgG Production
Chemical class Allergens; Glycerol
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2024-07-31
Route TOPICAL
Dosage form LIQUID
Substance GLYCERIN; NIACINAMIDE
Why two NDCs? The FDA registers this code as 84601-001-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 84601-0001-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerRIVER SUNZ co.,Ltd
FDA applicationM016 (OTC MONOGRAPH DRUG)
Labeler code84601
First marketedJul 2024
Product typeHuman Otc Drug
Portfolio4 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is a topical liquid essence marketed as an anti-aging repair product. It contains niacinamide (also called vitamin B3), commonly used in skincare to help reduce the appearance of fine lines and support skin barrier function, and glycerin, a humectant typically used to help the skin retain moisture. As an OTC monograph product, it is made under FDA's established rules for this category of cosmetic-like skincare products.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII TR046Y3K1G
    A liquid alcohol derived from petroleum or plant sources. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
  • UNII 344S277G0Z
    Allantoin is a naturally derived compound that helps soften and soothe skin. In medicines, it works as a skin-conditioning agent and may help support wound healing and reduce irritation in topical formulations.
  • UNII 9E8X80D2L0
    A synthetic form of vitamin E used as an antioxidant and preservative in medications. It helps prevent the active ingredients from degrading when exposed to oxygen or light.
  • UNII 37SXO36KR7
    A plant extract from the uva-ursi shrub, traditionally used in herbal preparations. In medicines, it may serve as a natural flavoring or botanical ingredient contributing to the product's formulation.
  • UNII 3XUS85K0RA
    Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
  • UNII UPY805K99W
    A synthetic compound derived from caprylic acid that works as a preservative and antimicrobial agent to help prevent bacterial and fungal growth in the medicine.
  • UNII 0A5MM307FC
    A synthetic polymer that absorbs water and forms a thick, gel-like substance. In medicines, it works as a thickener and stabilizer to improve texture and help ingredients stay mixed together in creams, gels, and lotions.
  • UNII H895X08VNQ
    A silicone-based polymer that forms small, hard particles. It acts as a glidant and anti-caking agent to improve powder flow and prevent clumping in tablets and capsules.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII 7CTH8MD549
    A natural plant extract from gardenia fruit used as a colorant in medicines. It provides yellow to orange coloring and may help preserve product stability.
  • UNII 6UV4YRY65X
    A protein found on blood cell surfaces that plays a role in clotting. It's used in some injectable medications as an active biological component to help achieve the drug's therapeutic effect.
  • UNII 2788Z9758H
    A plant extract from licorice root used as a sweetener, flavoring agent, and natural emulsifier in medicines. It helps improve taste and may aid in keeping ingredients evenly mixed throughout the product.
  • UNII 31T0FF0472
    A red microalgae used as a natural colorant and source of astaxanthin pigment in medications and supplements. It adds color to tablets and capsules.
  • UNII L25414IE41
    A synthetic peptide made of six amino acids linked together. It functions as a conditioning agent in topical formulations to help improve skin texture and appearance.
  • UNII YSE9PPT4TH
    Hyaluronate sodium is a natural carbohydrate that holds moisture. It's used in medicines as a lubricant, thickener, and moisture-retaining agent to improve texture and delivery of the active ingredient.
  • UNII S270N0TRQY
    Hyaluronic acid is a naturally occurring substance found in skin and joints. In medicines, it acts as a moisturizer and thickening agent to improve texture and help the product spread smoothly.
  • UNII J2S07SB0YL
    A protein derived from wheat that has been broken down into smaller pieces using enzymes. It's used in formulations as a film-former and texturizer to help bind ingredients together and improve product consistency.
  • UNII G1L3HT4CMH
    A synthetic compound used in medicines as a preservative and antimicrobial agent. It helps prevent bacterial and fungal growth, extending the product's shelf life.
  • UNII 4U3GMG1OT1
    A humectant and skin-conditioning agent derived from cellulose or similar plant sources. It helps retain moisture in the formulation and may improve texture or spreadability in topical products.
  • UNII 3K209OP33H
    A beneficial bacterium added to support gut health and digestion. It acts as a probiotic, helping maintain healthy intestinal bacteria balance in the product formulation.
  • UNII 8JC99XGU4W
    Soluble fish skin collagen is a protein derived from fish skin that acts as a binder and thickening agent in medicines. It helps hold ingredients together and gives the product the right texture or consistency.
  • UNII C9H2L21V7U
    A fat derived from coconut or palm oil containing shorter fatty acid chains. It serves as a solvent and carrier to help dissolve or suspend active ingredients, improving absorption and stability in liquid formulations.
  • UNII M8YIA49Q2P
    Morus alba leaf is a plant-derived ingredient used in some formulations as a natural filler and potential thickening agent. It may help give the product body and texture.
  • UNII KK181SM5JG
    A synthetic peptide derived from amino acids. In medications and cosmetic formulations, it functions as an active conditioning agent to help maintain skin texture and firmness in topical products.
  • UNII Q41S464P1R
    A synthetic peptide (short protein-like molecule) used in skincare and cosmetic formulations as an active conditioning ingredient to help improve skin texture and appearance. It may function as a humectant or skin-conditioning agent in topical products.
  • UNII 2A3916MQHO
    A synthetic peptide derived from palm oil that functions as a skin-conditioning agent and emollient. In formulations, it helps soften and smooth the product texture while providing moisturizing properties to topical preparations.
  • UNII 50C1307PZG
    Pentylene glycol is a humectant and preservative helper derived from petroleum or plant sources. It draws moisture into the product and helps prevent bacterial growth, keeping medicines stable during storage.
  • UNII 7T1F30V5YH
    A synthetic emulsifier derived from sorbitol and oleic acid. It helps mix oil and water-based ingredients together and keeps them from separating in liquid formulations.
  • UNII RS999V57DU
    Pomegranate fruit rind is a natural plant extract used as a coloring agent and flavoring ingredient in medicines. It may provide a reddish tint and fruity taste to tablets, capsules, or liquids.
  • UNII 39TG2H631E
    A short-chain protein fragment made of three amino acids linked together. It is used in cosmetic and skincare formulations as a conditioning or skin-soothing agent.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII 18920M3T13
    Rosa damascena flower oil is a fragrant plant oil extracted from damask rose petals. It's used in medicines as a flavoring and aromatic agent to improve taste and scent.
  • UNII 969IQC5YJU
    A natural plant extract from the rugosa rose flower. It's used in formulations as a fragrance, flavor, or natural colorant to improve the taste, smell, or appearance of the medicine.
  • UNII 2YGO1190AP
    A plant-derived carbohydrate from yeast or fungi, chemically modified to carry sodium and carboxyl groups. It acts as a thickener, stabilizer, and binder in medications to improve texture, consistency, and shelf life.
  • UNII 22ADO53M6F
    A mineral salt derived from phosphoric acid, used as a buffer to maintain the pH balance of the medication and help stabilize the active ingredients.
  • UNII 469OTG57A2
    Sodium pyrrolidone carboxylate is a synthetic polymer derived from pyrrolidone chemistry. It functions as a solubilizer and binder in medications, helping dissolve poorly water-soluble drugs and hold tablet ingredients together.
  • UNII 9O3K93S3TK
    Trolamine is an alkaline compound used as a pH buffer and emulsifier in medicines. It helps neutralize acids, stabilize formulations, and enable mixing of oil and water-based ingredients.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

38 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesROSA DAMASCENA FLOWER WATER LACTOBACILLUS FERMENT LACTOBACILLUS FERMENT LYSATE ROSA RUGOSA FLOWER EXTRACT HYDROXYACETOPHENONE 1,2-HEXANEDIOL TRIPEPTIDE-1 HEXAPEPTIDE-9 PALMITOYL TRIPEPTIDE-5 PALMITOYL PENTAPEPTIDE-4 PALMITOYL TETRAPEPTIDE-7 GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT MORUS ALBA LEAF EXTRACT PUNICA GRANATUM PERICARP EXTRACT ARCTOSTAPHYLOS UVA-URSI EXTRACT SODIUM HYALURONATE HYDROXYPROPYL TETRAHYDROPYRANTRIOL DECAPEPTIDE-4 GLYCOPROTEINS PROPYLENE GLYCOL BETA-GLUCAN ROSA HYBRID FLOWER EXTRACT GARDENIA FLORIDA FRUIT EXTRACT TRIETHANOLAMINE ROSA DAMASCENA FLOWER OIL OLIGOPEPTIDE-1 OLIGOPEPTIDE-5 OLIGOPEPTIDE-2 COLLAGEN HYALURONIC ACID HAEMATOCOCCUS PLUVIALIS EXTRACT CAPRYLIC/CAPRIC TRIGLYCERIDE PENTYLENE GLYCOL SODIUM DNA CAPRYLHYDROXAMIC ACID ETHYLHEXYLGLYCERIN WATER CARBOMER BUTYLENE GLYCOL POLYSORBATE 20 DISODIUM PHOSPHATE TOCOPHERYL ACETATE

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Atti amour Rose Anti-Aging Repair Classic Essence 6 g/100mL; 4 g/100mLthis 84601-0001-01 RIVER 100 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2024
On the market since
Jul 2024
📍
2026
Currently FDA-listed
2 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
84601-0001-01 You're viewing this 100 mL in 1 BOTTLE (84601-001-01) 2024-07-31 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 84601-001-01, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 84601-0001-01, written without dashes as 84601000101. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 84601-0001-01, the first segment (84601) is the labeler code FDA assigned to RIVER SUNZ co.,Ltd; the middle segment (0001) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by RIVER SUNZ co.,Ltd. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
RIVER SUNZ co.,Ltd is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 8 words ▾

Heips with skin whitening and wrinkle improve ment.

⏱️ Dosage and Administration 14 words ▾

Directions Take an appropriate amount of the product and evenlyspread it on the skin.

⚠️ Warnings 65 words ▾

For external use only When using this product Refrain from using on wounds or damaged areas. Stop use and ask a doctor if any abnormal symptoms or side effects, such as redness, swe llingor itching,occur in the area of application during or after using the cosmetic product. Keep out of reach of children ifswallowed , get medical help or contact a Poison Control Centernight away.

📦 Storage and Handling 10 words ▾

Store in a cool and dark place away from light

🧪 Active Ingredient 4 words ▾

NIACINAMIDE 4% GLYCERIN 6%

🧪 Inactive Ingredients 89 words ▾

ROSA DAMASCENA FLOWER WATER LACTOBACILLUS FERMENT LACTOBACILLUS FERMENT LYSATE ROSA RUGOSA FLOWER EXTRACT HYDROXYACETOPHENONE 1,2-HEXANEDIOL TRIPEPTIDE-1 HEXAPEPTIDE-9 PALMITOYL TRIPEPTIDE-5 PALMITOYL PENTAPEPTIDE-4 PALMITOYL TETRAPEPTIDE-7 GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT MORUS ALBA LEAF EXTRACT PUNICA GRANATUM PERICARP EXTRACT ARCTOSTAPHYLOS UVA-URSI EXTRACT SODIUM HYALURONATE HYDROXYPROPYL TETRAHYDROPYRANTRIOL DECAPEPTIDE-4 GLYCOPROTEINS PROPYLENE GLYCOL BETA-GLUCAN ROSA HYBRID FLOWER EXTRACT GARDENIA FLORIDA FRUIT EXTRACT TRIETHANOLAMINE ROSA DAMASCENA FLOWER OIL OLIGOPEPTIDE-1 OLIGOPEPTIDE-5 OLIGOPEPTIDE-2 COLLAGEN HYALURONIC ACID HAEMATOCOCCUS PLUVIALIS EXTRACT CAPRYLIC/CAPRIC TRIGLYCERIDE PENTYLENE GLYCOL SODIUM DNA CAPRYLHYDROXAMIC ACID ETHYLHEXYLGLYCERIN WATER CARBOMER BUTYLENE GLYCOL POLYSORBATE 20 DISODIUM PHOSPHATE TOCOPHERYL ACETATE

🎯 Purpose 8 words ▾

Heips with skin whitening and wrinkle improve ment.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 84589-0002-10 · LEDA 84601-0002-01 · RIVER →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.