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J1571

J1571 – Injection, hepatitis b immune globulin (hepagam b), intramuscular, 0.5 m · NDC Crosswalk & Billing Units

HCPCS Level II J-code · Medicare Part B drug billing
J-code ● 2 NDCs crosswalked per 0.5 ML $65.610/unit ASP+6%

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

📋 J1571 summary

J1571 is a HCPCS Level II J-code used to bill hepatitis b immune globulin (hepagam b), intramuscular, 0.5 ml, billed per 0.5 ML. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J1571: Hepagam B(J1571), Hepagam B

Code J1571 Billing unit 0.5 ML Payment limit $65.610/unit NDC-Crosswalk 2 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ1571
DescriptorInjection, hepatitis b immune globulin (hepagam b), intramuscular, 0.5 ml
Billing unit0.5 ML
Payment limit / unit$65.610
Est. ASP / unit$61.896 est.
Mapped NDCs2
Data periodQ3 2026
Last updated2026-08-20

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$65.610
Est. ASP / unit
$61.896 est.
Est. after 2% sequester
$64.298
HCPCS dosage
0.5 ML
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, hepatitis b immune globulin (hepagam b), intramuscular, 0.5 ml
CoverageD — Special coverage instructions apply
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment groupYY
Action codeN — No maintenance this year
Effective date2009-01-01
Date added2008-01-01
Source: CMS HCPCS Level II code file (imported via admin).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J1571 = 0.5 ml. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J1571 WITH EST. MEDICARE PAY

2 NDCs map to J1571. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($65.610/unit) × that package's bill units.
NDC (11-digit)DrugLabelerPackageStrength Bill units Est. pay / pkg NADAC / unit StatusSource
49591-0051-51 HepaGam B HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN 312 [iU]/mL INJECTION, SOLUTION Kamada 1 VIAL, GLASS in 1 CARTON (49591-051-51)... 312 [iU]/mL 10 $656.10 — ● Active CMS ASP
49591-0052-51 HepaGam B HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN 312 [iU]/mL INJECTION, SOLUTION Kamada 1 VIAL, GLASS in 1 CARTON (49591-052-51)... 312 [iU]/mL 2 $131.22 — ● Active CMS ASP
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

📊 Medicare utilization & spend CMS · PART B · 2025 (Q1-Q4)

Total Part B spend
$30.4K
Claims
32
Beneficiaries
13
Spend / beneficiary
$2,342.03
Spend / claim
$951.45
Where J1571 ranks among Part B drugs · 2025 (Q1-Q4) · neighbors ±5
Total spending — #756 of 918
#751 AFLURIA (90657)* 90657 $35.4K #752 ARGATROBAN-0.9% NACL... J0883 $34.9K #753 NAFCILLIN SODIUM J2290 $34.2K #754 LEVOLEUCOVORIN CALCI... J0641 $32.9K #755 MEROPENEM(J2183) J2183 $30.9K #756 HEPAGAM B(J1571) J1571 $30.4K #757 BUPIVACAINE HCL* J0665 $28.1K #758 HYLENEX J3473 $28.1K #759 PREMARIN J1410 $27.2K #760 CALCIUM GLUCONATE-NA... J0612 $26K #761 DELESTROGEN* J1380 $25.3K
Total claims — #873 of 918
#868 CINRYZE J0598 34 #869 DAPTOMYCIN-0.9% NACL J0874 34 #870 CALDOLOR J1741 34 #871 YESINTEK Q5100 34 #872 RYLAZE J9021 33 #873 HEPAGAM B(J1571) J1571 32 #874 GAMMAGRAFT** Q4111 32 #875 TERBUTALINE SULFATE J3105 30 #876 ALHEMO PEN J7173 30 #877 ZENITH AMNIOTIC MEMB... Q4253 30 #878 VARUBI J8670 29

Full breakdown by period (1)
PeriodTotal spendBeneficiariesClaims$/beneficiary$/claim
2025 (Q1-Q4) $30.4K 13 32 $2,342.03 $951.45
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.

📈 Medicare Part B claims detail CMS PSPS · 2024

Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
—
Medicare paid
$561.84
Submitted services
—
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.

🗺️ Where J1571 is utilized

⏳
The geographic utilization map is building for this code — it aggregates millions of CMS Part B claim lines, then caches the result. Refresh in a moment; if it doesn’t appear, this code may have no reportable Part B utilization.

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk
2 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2025
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

  • A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
  • Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
  • Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
  • Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
  • The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
  • Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J1571 billing FAQ

What is HCPCS code J1571?
J1571 is a HCPCS Level II J-code used to bill Injection, hepatitis b immune globulin (hepagam b), intramuscular, 0.5 ml under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J1571?
One unit of J1571 represents 0.5 ML. Report the number of units equal to the dose administered divided by 0.5 ML.
How many units of J1571 should I bill?
Divide the dose administered by the code's unit size (0.5 ML) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J1571?
The Medicare Part B payment limit is $65.610 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $64.298 per unit. Payment limits are revised quarterly.
Which NDCs bill under J1571?
2 NDCs currently map to J1571 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J1571 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.