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J1573

J1573 – Injection, hepatitis b immune globulin (hepagam b), intravenous, 0.5 ml · NDC Crosswalk & Billing Units

HCPCS Level II J-code · Medicare Part B drug billing

J-code ● 2 NDCs crosswalked per 0.5 ML $65.610/unit ASP+6%

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

📋 J1573 summary

J1573 is a HCPCS Level II J-code used to bill hepatitis b immune globulin (hepagam b), intravenous, 0.5 ml, billed per 0.5 ML. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J1573: Hepagam B(J1573), Hepagam B

Code J1573 Billing unit 0.5 ML Payment limit $65.610/unit NDC-Crosswalk 2 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ1573

DescriptorInjection, hepatitis b immune globulin (hepagam b), intravenous, 0.5 ml

Billing unit0.5 ML

Payment limit / unit$65.610

Est. ASP / unit$61.896 est.

Mapped NDCs2

Data periodQ3 2026

Last updated2026-08-20

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).

Medicare payment limit / unit

$65.610

Est. ASP / unit

$61.896 est.

Est. after 2% sequester

$64.298

HCPCS dosage

0.5 ML

The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.

Full HCPCS code details (official CMS record)

Long descriptionInjection, hepatitis b immune globulin (hepagam b), intravenous, 0.5 ml

CoverageC — Carrier/MAC judgment

Pricing indicator51 — Drug — priced under the ASP methodology

Type of service1 — Medical care

BETOS-2O1E

ASC payment groupYY

Action codeN — No maintenance this year

Effective date2009-01-01

Date added2008-01-01

Source: CMS HCPCS Level II code file (imported via admin).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J1573 = 0.5 ml. Enter a regimen to convert dose → billing units and project a full course.

Dose per administration (ml) Frequency — every days Number of doses NDC / package billed (optional)

Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J1573 WITH EST. MEDICARE PAY

2 NDCs map to J1573. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($65.610/unit) × that package's bill units.

NDC (11-digit)	Drug	Labeler	Package	Strength	Bill units	Est. pay / pkg	NADAC / unit	Status	Source
49591-0051-51	HepaGam B HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN 312 [iU]/mL INJECTION, SOLUTION	Kamada	1 VIAL, GLASS in 1 CARTON (49591-051-51)...	312 [iU]/mL	10	$656.10	—	● Active	CMS ASP
49591-0052-51	HepaGam B HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN 312 [iU]/mL INJECTION, SOLUTION	Kamada	1 VIAL, GLASS in 1 CARTON (49591-052-51)...	312 [iU]/mL	2	$131.22	—	● Active	CMS ASP

NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

⚠️ Don't confuse J1573 with… RELATED CODES

Adjacent HCPCS codes that share an ingredient or formulation with J1573. Billing units and payment limits differ — confirm the exact code, strength and form before billing.

Code	Descriptor	Billing unit	Payment limit / unit	How it differs from J1573
J1571	Hepagam b im injection	0.5 ML	$65.610	Related ingredient or formulation — confirm strength, form and billing unit before substituting.

Related codes matched on shared ingredient (CMS Medicare Part B Spending feed). Billing units and payment limits from the CMS ASP Pricing File. Always verify the precise HCPCS code for the product and strength administered.

📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)

Period

Total Part B spend

$68.1K

Claims

Beneficiaries

Spend / beneficiary

$4,254.05

Spend / claim

$2,836.03

Trend by period

Where J1573 ranks among Part B drugs · 2026 (Q1) · neighbors ±5

Total spending — #593 of 824

#588 REVITA, PER SQ CM** Q4180 $71.6K #589 SODIUM CHLORIDE(J705... J7050 $71.5K #590 FOSAPREPITANT DIMEGL... J1456 $70.3K #591 AMNIOWRAP2 PER SQ CM... Q4221 $70.1K #592 PROHANCE MULTIPACK A9576 $69.9K #593 HEPAGAM B(J1573) J1573 $68.1K #594 LUMASON Q9950 $68K #595 AFLURIA (90658)* 90658 $65.9K #596 PREDNISONE INTENSOL* J7512 $63.9K #597 BIOVANCE 1 SQUARE CM... Q4154 $62.8K #598 INTEGRA MATRIX** Q4108 $61.9K

Total claims — #768 of 824

#763 ALDURAZYME J1931 25 #764 ESPEROCT J7204 25 #765 ACTEMRA(Q0249) Q0249 25 #766 INTEGRA MATRIX** Q4108 25 #767 EPINEPHRINE J0166 24 #768 HEPAGAM B(J1573) J1573 24 #769 YUTIQ J7314 24 #770 GAMIFANT J9210 24 #771 COMBOGESIC IV J0138 23 #772 CEFAZOLIN SODIUM(J06... J0688 23 #773 DAPTOMYCIN-0.9% NACL J0874 23

Full breakdown by period (2)

Period	Total spend	Beneficiaries	Claims	$/beneficiary	$/claim
2026 (Q1)	$68.1K	16	24	$4,254.05	$2,836.03
2025 (Q1-Q4)	$198.7K	25	75	$7,947.83	$2,649.28

Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.

HCPCS code & descriptor

CMS HCPCS Level II code file

Loaded

Payment limit & billing unit

CMS Medicare Part B ASP Pricing File (quarterly)

Q3 2026 · as of 2026-08-20

NDC ↔ HCPCS crosswalk

CMS ASP NDC-HCPCS crosswalk

2 NDCs mapped

NADAC acquisition cost

CMS National Average Drug Acquisition Cost (weekly)

Not available for mapped NDCs

Utilization & spend

CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners

Latest data year 2026

Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J1573 billing FAQ

What is HCPCS code J1573?

J1573 is a HCPCS Level II J-code used to bill Injection, hepatitis b immune globulin (hepagam b), intravenous, 0.5 ml under Medicare Part B and most medical (not pharmacy) benefits.

What is the billing unit for J1573?

One unit of J1573 represents 0.5 ML. Report the number of units equal to the dose administered divided by 0.5 ML.

How many units of J1573 should I bill?

Divide the dose administered by the code's unit size (0.5 ML) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.

How much does Medicare pay for J1573?

The Medicare Part B payment limit is $65.610 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $64.298 per unit. Payment limits are revised quarterly.

Which NDCs bill under J1573?

2 NDCs currently map to J1573 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.

Does a crosswalk mean J1573 is covered?

No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.

For professional billing reference only — verify against the current CMS files before submitting claims.