J3410
J3410 – Injection, hydroxyzine hcl, up to 25 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 14 NDCs crosswalked per 25 MG $15.209/unit ASP+6%
📋 J3410 summary
J3410 is a HCPCS Level II J-code used to bill hydroxyzine hcl, up to 25 mg, billed per 25 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Brand names associated with J3410: Hydroxyzine Hydrochloride, Hydroxyzine
Code J3410
Billing unit 25 MG Payment limit $15.209/unit NDC-Crosswalk 14
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ3410
DescriptorInjection, hydroxyzine hcl, up to 25 mg
Billing unit25 MG
Payment limit / unit$15.209
Est. ASP / unit$14.348 est.
Mapped NDCs14
Data periodQ3 2026
Last updated2026-08-20
💊 About Hydroxyzine DRUG GUIDE
Hydroxyzine is used to relieve anxiety and tension related to psychoneurosis (anxiety-based mental health conditions) and as a supportive treatment when anxiety is part of another medical condition.
Oral forms — including tablets, capsules, and oral solution — are used for anxiety relief and to manage itching (pruritus) caused by allergic conditions such as chronic urticaria (hives), atopic dermatitis, contact dermatitis, and histamine-driven itch.
Oral forms are also used as a sedative before and after surgery or general anesthesia.Hydroxyzine Hydrochloride intramuscular injection is used specifically when a shot is needed — for example, in acute psychiatric or emotional emergencies, acute alcohol withdrawal with anxiety symptoms or delirium tremens, control of nausea and vomiting (except during pregnancy), and as pre- and post-operative or pre- and post-partum supportive medication to reduce narcotic requirements and control nausea.
Clinical overview from our editorial drug guide for Hydroxyzine. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$15.209
Est. ASP / unit
$14.348 est.
Est. after 2% sequester
$14.905
HCPCS dosage
25 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, hydroxyzine hcl, up to 25 mg
CoverageD — Special coverage instructions apply
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment group—
Action codeN — No maintenance this year
Effective date1997-01-01
Date added1982-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J3410 = 25 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J3410 WITH EST. MEDICARE PAY
14 NDCs map to J3410. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($15.209/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00404-9877-01 | Hydroxyzine Hydrochloride 50 mg/mL INJECTION, SOLUTION | Henry | 1 VIAL, SINGLE-DOSE in 1 BAG (0404-9877-01... | 50 mg/mL | 2 | $30.42 | — | ● Active | CMS ASP |
| 00404-9878-02 | Hydroxyzine 50 mg/mL INJECTION, SOLUTION | Henry | 1 VIAL, SINGLE-DOSE in 1 BAG (0404-9878-02... | 50 mg/mL | 4 | $60.84 | — | ● Active | CMS ASP |
| 00517-4201-25 | Hydroxyzine Hydrochloride 25 mg/mL INJECTION, SOLUTION | American | 25 VIAL, SINGLE-DOSE in 1 TRAY (0517-4201-... | 25 mg/mL | 25 | $380.23 | — | ● Active | CMS + PDAC |
| 00517-5601-25 | Hydroxyzine Hydrochloride 50 mg/mL INJECTION, SOLUTION | American | 25 VIAL, SINGLE-DOSE in 1 TRAY (0517-5601-... | 50 mg/mL | 50 | $760.45 | — | ● Active | CMS + PDAC |
| 00517-5602-25 | Hydroxyzine Hydrochloride 50 mg/mL INJECTION, SOLUTION | American | 25 VIAL, SINGLE-DOSE in 1 TRAY (0517-5602-... | 50 mg/mL | 100 | $1,520.90 | — | ● Active | CMS + PDAC |
| 51662-1649-03 | HYDROXYZINE HYDROCHLORIDE 25 mg/mL INJECTION, SOLUTION | HF | 25 POUCH in 1 CASE (51662-1649-3) / 1 VIA... | 25 mg/mL | 25 | $380.23 | — | ● Active | CMS ASP |
| 00517-4201-01 | HYDROXYZINE HCL (SDV) 25 MG/1 ML | Unknown | — | — | 1 | $15.21 | — | — | PDAC |
| 00517-5601-01 | HYDROXYZINE HCL (SDV) 50 MG/1 ML | Unknown | — | — | 2 | $30.42 | — | — | PDAC |
| 00517-5602-01 | HYDROXYZINE HCL (SDV) 50 MG/1 ML | Unknown | — | — | 2 | $30.42 | — | — | PDAC |
| 51927-1400-00 | HYDROXYZINE HCL (U.S.P.) | Unknown | — | — | 40 | $608.36 | — | — | PDAC |
| 38779-0298-04 | Hydroxyzine Hydrochloride 1 g/g POWDER | Medisca | 25 g in 1 JAR (38779-0298-4) | 1 g/g | 40 | $608.36 | — | ● Active | PDAC |
| 38779-0298-05 | Hydroxyzine Hydrochloride 1 g/g POWDER | Medisca | 100 g in 1 JAR (38779-0298-5) | 1 g/g | 40 | $608.36 | — | ● Active | PDAC |
| 54868-0858-00 | HYDROXYZINE HCL (VIAL) 25 MG/ML | Unknown | — | — | 1 | $15.21 | — | — | PDAC |
| 49452-3652-02 | HYDROXYZINE HCL (U.S.P.) | Unknown | — | — | 40 | $608.36 | — | — | PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)
Period
Total Part B spend
$391.37
Claims
20
Beneficiaries
17
Spend / beneficiary
$23.02
Spend / claim
$19.57
Trend by period
Where J3410 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #791 of 824
#786
DAPTOMYCIN(J0873) J0873
$474.41
#787
MEDROL* J7509
$471.06
#788
AFLURIA (90657)* 90657
$440.18
#789
AZITHROMYCIN* J0456
$419.17
#790
VALPROATE SODIUM J3379
$414.28
#791
HYDROXYZINE HCL J3410
$391.37
#792
FOLIC ACID J1808
$341.31
#793
METHOTREXATE* J8610
$338.59
#794
PHENYLEPHRINE HCL-0.... J2371
$334.54
#795
CALCIUM GLUCONATE-NA... J0613
$319.51
#796
FLUCONAZOLE-NACL J1450
$308.26
Total claims — #786 of 824
#781
BENTYL* J0500
21
#782
SIGNIFOR LAR J2502
21
#783
AFSTYLA J7210
21
#784
SURGRAFT FT PER SQ C... Q4268
21
#785
CHLOROPROCAINE HCL* J2401
20
#786
HYDROXYZINE HCL J3410
20
#787
ALHEMO PEN J7173
20
#788
ALPHANINE SD J7193
20
#789
DUAL LAYER IMPAX, PE... Q4262
20
#790
BENZTROPINE MESYLATE J0515
19
#791
STELARA(J3357)* J3357
19
Top Medicare Part B drugs by the selected metric. Click any drug to open its J-code page. Source: CMS Medicare Quarterly Part B Spending by Drug.
Full breakdown by period (2)
| Period | Total spend | Beneficiaries | Claims | $/beneficiary | $/claim |
|---|---|---|---|---|---|
| 2026 (Q1) | $391.37 | 17 | 20 | $23.02 | $19.57 |
| 2025 (Q1-Q4) | $3.2K | 122 | 165 | $26.61 | $19.67 |
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$2K
Medicare paid
$2.1K
Submitted services
135
Submitted charges
$5.2K
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
🗺️ Where J3410 is utilized CMS · BY PROVIDER · 2024
Medicare Part B services for this code by the rendering provider's state — 127 services across 2 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.
Hover or tap a state to see its numbers + top ZIP codes.
Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.
📊 What bills under J3410
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
14 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J3410 billing FAQ
What is HCPCS code J3410?
J3410 is a HCPCS Level II J-code used to bill Injection, hydroxyzine hcl, up to 25 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J3410?
One unit of J3410 represents 25 MG. Report the number of units equal to the dose administered divided by 25 MG.
How many units of J3410 should I bill?
Divide the dose administered by the code's unit size (25 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J3410?
The Medicare Part B payment limit is $15.209 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $14.905 per unit. Payment limits are revised quarterly.
Which NDCs bill under J3410?
14 NDCs currently map to J3410 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J3410 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.