J9280
J9280 – Injection, mitomycin, 5 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 37 NDCs crosswalked per 5 MG $34.107/unit ASP+6%
📋 J9280 summary
J9280 is a HCPCS Level II J-code used to bill mitomycin, 5 mg, billed per 5 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Brand names associated with J9280: Mutamycin
Code J9280
Billing unit 5 MG Payment limit $34.107/unit NDC-Crosswalk 37
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ9280
DescriptorInjection, mitomycin, 5 mg
Billing unit5 MG
Payment limit / unit$34.107
Est. ASP / unit$32.176 est.
Mapped NDCs37
Data periodQ3 2026
Last updated2026-08-20
💊 About Mitomycin DRUG GUIDE
Mitomycin (and its brand Mutamycin) is used intravenously in combination with other chemotherapy drugs to treat disseminated adenocarcinoma (a type of cancer that has spread) of the stomach or pancreas, when other treatments have not worked.
It is not intended to replace surgery or radiation therapy.Mitomycin is also the active ingredient in other products for different uses: Jelmyto treats low-grade upper tract urothelial cancer (cancer of the upper urinary tract); Zusduri treats recurrent low-grade intermediate-risk non-muscle invasive bladder cancer; and Mitosol is used as a surgical aid during certain glaucoma eye surgery.
These are separate products with distinct indications and are not interchangeable with the intravenous injection form.
Clinical overview from our editorial drug guide for Mitomycin. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$34.107
Est. ASP / unit
$32.176 est.
Est. after 2% sequester
$33.425
HCPCS dosage
5 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, mitomycin, 5 mg
CoverageD — Special coverage instructions apply
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1D
ASC payment groupYY
Action codeN — No maintenance this year
Effective date2013-01-01
Date added1986-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J9280 = 5 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J9280 WITH EST. MEDICARE PAY
37 NDCs map to J9280. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($34.107/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00143-9135-01 | Mitomycin 20 mg/1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hikma | 1 VIAL in 1 BOX (0143-9135-01) / 1 INJECT... | 20 mg/1 | 4 | $136.43 | — | ● Active | CMS + PDAC |
| 00143-9136-01 | Mitomycin 40 mg/1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hikma | 1 VIAL in 1 BOX (0143-9136-01) / 1 INJECT... | 40 mg/1 | 8 | $272.86 | — | ● Active | CMS + PDAC |
| 00143-9279-01 | Mitomycin 20 mg/40mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hikma | 1 VIAL in 1 BOX, UNIT-DOSE (0143-9279-01)... | 20 mg/40mL | 4 | $136.43 | — | ● Active | CMS + PDAC |
| 00143-9280-01 | Mitomycin 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hikma | 1 VIAL in 1 BOX, UNIT-DOSE (0143-9280-01)... | 40 mg/80mL | 8 | $272.86 | — | ● Active | CMS + PDAC |
| 16729-0115-05 | Mitomycin 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Accord | 1 VIAL in 1 CARTON (16729-115-05) / 10 mL... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS ASP |
| 16729-0116-38 | Mitomycin 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Accord | 1 VIAL in 1 BOX, UNIT-DOSE (16729-116-38)... | 40 mg/80mL | 8 | $272.86 | — | ● Active | CMS ASP |
| 25021-0250-20 | Mitomycin 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 1 VIAL in 1 CARTON (25021-250-20) / 10 mL... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS + PDAC |
| 25021-0251-50 | Mitomycin 20 mg/40mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 1 VIAL in 1 CARTON (25021-251-50) / 40 mL... | 20 mg/40mL | 4 | $136.43 | — | ● Active | CMS + PDAC |
| 25021-0252-51 | Mitomycin 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 1 VIAL in 1 CARTON (25021-252-51) / 80 mL... | 40 mg/80mL | 8 | $272.86 | — | ● Active | CMS + PDAC |
| 55150-0450-01 | MITOMYCIN 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Eugia | 1 VIAL, SINGLE-DOSE in 1 CARTON (55150-450... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS + PDAC |
| 55150-0451-01 | MITOMYCIN 20 mg/40mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Eugia | 1 VIAL, SINGLE-DOSE in 1 CARTON (55150-451... | 20 mg/40mL | 4 | $136.43 | — | ● Active | CMS + PDAC |
| 55150-0452-01 | MITOMYCIN 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Eugia | 1 VIAL, SINGLE-DOSE in 1 CARTON (55150-452... | 40 mg/80mL | 8 | $272.86 | — | ● Active | CMS + PDAC |
| 65219-0564-20 | MITOMYCIN 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Fresenius | 1 VIAL in 1 CARTON (65219-564-20) / 10 mL... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS + PDAC |
| 65219-0566-20 | MITOMYCIN 20 mg/40mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Fresenius | 1 VIAL in 1 CARTON (65219-566-20) / 40 mL... | 20 mg/40mL | 4 | $136.43 | — | ● Active | CMS + PDAC |
| 65219-0568-00 | MITOMYCIN 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Fresenius | 1 VIAL, SINGLE-DOSE in 1 CARTON (65219-568... | 40 mg/80mL | 8 | $272.86 | — | ● Active | CMS + PDAC |
| 68001-0389-36 | Mitomycin 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BluePoint | 1 VIAL in 1 CARTON (68001-389-36) / 10 mL... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS + PDAC |
| 68001-0615-36 | MITOMYCIN 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BluePoint | 1 VIAL, SINGLE-DOSE in 1 CARTON (68001-615... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS + PDAC |
| 68001-0616-77 | MITOMYCIN 20 mg/40mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BluePoint | 1 VIAL, SINGLE-DOSE in 1 CARTON (68001-616... | 20 mg/40mL | 4 | $136.43 | — | ● Active | CMS + PDAC |
| 68001-0617-79 | MITOMYCIN 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BluePoint | 1 VIAL, SINGLE-DOSE in 1 CARTON (68001-617... | 40 mg/80mL | 8 | $272.86 | — | ● Active | CMS + PDAC |
| 71288-0137-20 | MITOMYCIN 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Meitheal | 1 VIAL, SINGLE-DOSE in 1 CARTON (71288-137... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS + PDAC |
| 71288-0138-50 | MITOMYCIN 20 mg/40mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Meitheal | 1 VIAL, SINGLE-DOSE in 1 CARTON (71288-138... | 20 mg/40mL | 4 | $136.43 | — | ● Active | CMS + PDAC |
| 71288-0139-51 | MITOMYCIN 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Meitheal | 1 VIAL, SINGLE-DOSE in 1 CARTON (71288-139... | 40 mg/80mL | 8 | $272.86 | — | ● Active | CMS + PDAC |
| 72819-0152-05 | Mitomycin 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Archis | 1 VIAL in 1 CARTON (72819-152-05) / 10 mL... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS + PDAC |
| 72819-0152-95 | Mitomycin 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Archis | 1 VIAL in 1 CARTON (72819-152-95) / 10 mL... | 5 mg/10mL | 1 | $34.11 | — | ● Active | CMS + PDAC |
| 72819-0153-02 | Mitomycin 20 mg/40mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Archis | 1 VIAL in 1 CARTON (72819-153-02) / 40 mL... | 20 mg/40mL | 4 | $136.43 | — | ● Active | CMS + PDAC |
| 72819-0154-04 | Mitomycin 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Archis | 1 VIAL in 1 CARTON (72819-154-04) / 80 mL... | 40 mg/80mL | 8 | $272.86 | — | ● Active | CMS ASP |
| 72819-0154-02 | MITOMYCIN (SDV,PF,LYOPHILIZED) 40 MG | Unknown | — | — | 8 | $272.86 | — | — | PDAC |
| 69448-0001-05 | MUTAMYCIN Mitomycin 5 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Accord | 1 VIAL in 1 CARTON (69448-001-05) / 10 mL... | 5 mg/10mL | 1 | $34.11 | — | ● Active | PDAC |
| 69448-0003-38 | MUTAMYCIN Mitomycin 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Accord | 1 VIAL in 1 BOX, UNIT-DOSE (69448-003-38)... | 40 mg/80mL | 8 | $272.86 | — | ● Active | PDAC |
| 67457-0997-40 | PREMIERPRO RX MITOMYCIN (USP;SDV,PF,LYOPHILIZED) 40 MG | Unknown | — | — | 8 | $272.86 | — | — | PDAC |
| 67457-0996-20 | PREMIERPRO RX MITOMYCIN (USP;SDV,PF,LYOPHILIZED) 20 MG | Unknown | — | — | 4 | $136.43 | — | — | PDAC |
| 68001-0391-79 | Mitomycin 40 mg/80mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BluePoint | 1 VIAL in 1 BOX, UNIT-DOSE (68001-391-79)... | 40 mg/80mL | 8 | $272.86 | — | ● Active | PDAC |
| 68001-0390-77 | Mitomycin 20 mg/40mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BluePoint | 1 VIAL in 1 BOX, UNIT-DOSE (68001-390-77)... | 20 mg/40mL | 4 | $136.43 | — | ● Active | PDAC |
| 67457-0520-40 | MITOMYCIN (SDV,PF) 40 MG | Unknown | — | — | 8 | $272.86 | — | — | PDAC |
| 67457-0518-05 | MITOMYCIN (PF,LYOPHILIZED) 5 MG | Unknown | — | — | 1 | $34.11 | — | — | PDAC |
| 67457-0519-20 | MITOMYCIN (SDV,PF,LYOPHILIZED) 20 MG | Unknown | — | — | 4 | $136.43 | — | — | PDAC |
| 69448-0002-11 | MUTAMYCIN 20 MG | Unknown | — | — | 4 | $136.43 | — | — | PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)
Period
Total Part B spend
$262.7K
Claims
1,891
Beneficiaries
1,146
Spend / beneficiary
$229.23
Spend / claim
$138.92
Trend by period
Where J9280 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #503 of 824
#498
TDVAX* 90714
$282.9K
#499
AMNIO QUAD-CORE, PER... Q4294
$270.2K
#500
DAXXIFY J0589
$269.7K
#501
ALBUMIN (HUMAN)* P9041
$267.7K
#502
YUTIQ J7314
$263.2K
#503
MITOMYCIN J9280
$262.7K
#504
GADOTERIDOL* A9579
$262K
#505
BEIZRAY-ALBUMIN* J9174
$258.2K
#506
CYCLOPHOSPHAMIDE(J90... J9071
$255.9K
#507
ERTAPENEM J1335
$254.7K
#508
SURGRAFT TL, PER SQ... Q4263
$246.1K
Total claims — #325 of 824
#320
TOBRAMYCIN SULFATE J3260
1,945
#321
DILAUDID* J1171
1,926
#322
INVEGA SUSTENNA J2426
1,926
#323
ALBUTEROL SULFATE(J7... J7611
1,926
#324
VINCASAR PFS* J9370
1,920
#325
MITOMYCIN J9280
1,891
#326
EMTRICITABINE-TENOFO... J0750
1,859
#327
ZOLADEX J9202
1,858
#328
DAPTOMYCIN(J0872) J0872
1,843
#329
JEVTANA J9043
1,832
#330
QUZYTTIR J1201
1,770
Top Medicare Part B drugs by the selected metric. Click any drug to open its J-code page. Source: CMS Medicare Quarterly Part B Spending by Drug.
Full breakdown by period (2)
| Period | Total spend | Beneficiaries | Claims | $/beneficiary | $/claim |
|---|---|---|---|---|---|
| 2026 (Q1) | $262.7K | 1,146 | 1,891 | $229.23 | $138.92 |
| 2025 (Q1-Q4) | $1.5M | 4,205 | 8,860 | $357.13 | $169.49 |
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$1.23M
Medicare paid
$970.4K
Submitted services
44,006
Denial rate
6.1%
Allowed / service
$29.79
Submitted charges
$10.2M
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
🗺️ Where J9280 is utilized CMS · BY PROVIDER · 2024
Medicare Part B services for this code by the rendering provider's state — 7,417 services across 17 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.
Hover or tap a state to see its numbers + top ZIP codes.
Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.
📊 What bills under J9280
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
37 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J9280 billing FAQ
What is HCPCS code J9280?
J9280 is a HCPCS Level II J-code used to bill Injection, mitomycin, 5 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J9280?
One unit of J9280 represents 5 MG. Report the number of units equal to the dose administered divided by 5 MG.
How many units of J9280 should I bill?
Divide the dose administered by the code's unit size (5 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J9280?
The Medicare Part B payment limit is $34.107 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $33.425 per unit. Payment limits are revised quarterly.
Which NDCs bill under J9280?
37 NDCs currently map to J9280 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J9280 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.