J2274 NDC Crosswalk, Billing Units, ASP Payment & Medicare Reimbursement

📋 J2274 summary

J2274 is a HCPCS Level II J-code used to bill morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg, billed per 10 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J2274: Duramorph*, Morphine Sulfate, Duramorph

Code J2274 Billing unit 10 MG Payment limit $18.914/unit NDC-Crosswalk 21 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ2274

DescriptorInjection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg

Billing unit10 MG

Payment limit / unit$18.914

Est. ASP / unit$17.843 est.

Mapped NDCs21

Data periodQ3 2026

Last updated2026-08-20

💊 About Morphine Injection DRUG GUIDE

Morphine sulfate injection is used to manage severe pain that requires an opioid analgesic and cannot be adequately controlled by other treatments.

It is only prescribed when other pain-relief options have failed or are not tolerated.Infumorph 200 and Infumorph 500 are specifically used for continuous epidural or intrathecal (spinal) delivery through a microinfusion device, for patients with severe chronic pain requiring long-term opioid management.

Duramorph is used for single-dose epidural or intrathecal bolus injections as well as standard intravenous or intramuscular use.

Read the full Morphine Injection drug guide →

Clinical overview from our editorial drug guide for Morphine Injection. For billing reference, see the sections above.

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).

Medicare payment limit / unit

$18.914

Est. ASP / unit

$17.843 est.

Est. after 2% sequester

$18.536

HCPCS dosage

10 MG

The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.

Full HCPCS code details (official CMS record)

Long descriptionInjection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg

CoverageD — Special coverage instructions apply

Pricing indicator51 — Drug — priced under the ASP methodology

Type of service1 — Medical care

BETOS-2O1E

ASC payment group—

Action codeN — No maintenance this year

Effective date2018-01-01

Date added2015-01-01

Source: CMS HCPCS Level II code file (imported via admin).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J2274 = 10 mg. Enter a regimen to convert dose → billing units and project a full course.

Dose per administration (mg) Frequency — every days Number of doses NDC / package billed (optional)

Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J2274 LEAST EXPENSIVE FIRST

21 NDCs map to J2274. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($18.914/unit) × that package's bill units.

NDC (11-digit)	Drug	Labeler	Package	Strength	Bill units	Est. pay / pkg	NADAC / unit	Status	Source
00409-1893-01	Morphine Sulfate 10 mg/mL INJECTION, SOLUTION	Hospira,	10 CARTRIDGE in 1 CARTON (0409-1893-01) /...	10 mg/mL	1	$18.91	$1.595	Obsolete	PDAC
00409-3814-12	Morphine Sulfate .5 mg/mL INJECTION, SOLUTION	Hospira,	5 VIAL, GLASS in 1 CARTON (0409-3814-12)...	.5 mg/mL	3	$56.74	—	● Active	CMS + PDAC
00409-3815-12	Morphine Sulfate 1 mg/mL INJECTION, SOLUTION	Hospira,	5 VIAL, GLASS in 1 CARTON (0409-3815-12)...	1 mg/mL	5	$94.57	—	● Active	CMS + PDAC
00641-6019-10	Duramorph morphine sulfate 1 mg/mL INJECTION	Hikma	10 AMPULE in 1 CARTON (0641-6019-10) / 10...	1 mg/mL	10	$189.14	—	● Active	CMS + PDAC
00641-6020-10	Duramorph morphine sulfate .5 mg/mL INJECTION	Hikma	10 AMPULE in 1 CARTON (0641-6020-10) / 10...	.5 mg/mL	5	$94.57	—	● Active	CMS + PDAC
00641-6039-01	INFUMORPH 200 morphine sulfate 10 mg/mL INJECTION, SOLUTION	Hikma	20 mL in 1 AMPULE (0641-6039-01)	10 mg/mL	20	$378.28	—	● Active	CMS + PDAC
00641-6040-01	INFUMORPH 500 morphine sulfate 25 mg/mL INJECTION, SOLUTION	Hikma	20 mL in 1 AMPULE (0641-6040-01)	25 mg/mL	50	$945.70	—	● Active	CMS + PDAC
66794-0160-02	MITIGO Morphine Sulfate 200 mg/20mL INJECTION	Piramal	1 mL in 1 VIAL, SINGLE-USE (66794-160-02)	200 mg/20mL	20	$378.28	—	● Active	CMS + PDAC
66794-0162-02	MITIGO Morphine Sulfate 500 mg/20mL INJECTION	Piramal	1 mL in 1 VIAL, SINGLE-USE (66794-162-02)	500 mg/20mL	50	$945.70	—	● Active	CMS + PDAC
00641-6192-10	Morphine Sulfate 4 mg/mL INJECTION	Hikma	10 SYRINGE in 1 PACKAGE (0641-6192-10) /...	4 mg/mL	0.4	$7.57	—	● Active	PDAC
00641-6191-10	Morphine Sulfate 2 mg/mL INJECTION	Hikma	10 SYRINGE in 1 PACKAGE (0641-6191-10) /...	2 mg/mL	0.2	$3.78	—	● Active	PDAC
00409-1891-23	Morphine Sulfate 4 mg/mL INJECTION, SOLUTION	Hospira,	10 SYRINGE in 1 CELLO PACK (0409-1891-23)...	4 mg/mL	0.4	$7.57	—	Obsolete	PDAC
00409-1893-23	Morphine Sulfate 10 mg/mL INJECTION, SOLUTION	Hospira,	10 SYRINGE in 1 CELLO PACK (0409-1893-23)...	10 mg/mL	1	$18.91	—	● Active	PDAC
72572-0440-25	Morphine Sulfate 4 mg/mL INJECTION	Civica,	25 VIAL, SINGLE-DOSE in 1 PACKAGE (72572-4...	4 mg/mL	0.4	$7.57	—	● Active	PDAC
00409-1890-01	Morphine Sulfate 2 mg/mL INJECTION, SOLUTION	Hospira,	10 CARTRIDGE in 1 CARTON (0409-1890-01) /...	2 mg/mL	0.2	$3.78	—	● Active	PDAC
00409-1891-01	Morphine Sulfate 4 mg/mL INJECTION, SOLUTION	Hospira,	10 CARTRIDGE in 1 CARTON (0409-1891-01) /...	4 mg/mL	0.4	$7.57	—	● Active	PDAC
00409-1890-23	Morphine Sulfate 2 mg/mL INJECTION, SOLUTION	Hospira,	10 SYRINGE in 1 CELLO PACK (0409-1890-23)...	2 mg/mL	0.2	$3.78	—	● Active	PDAC
76045-0004-11	Morphine Sulfate 2 mg/mL INJECTION, SOLUTION	Fresenius	10 SYRINGE, GLASS in 1 CARTON (76045-004-1...	2 mg/mL	0.2	$3.78	—	● Active	PDAC
76045-0005-11	Morphine Sulfate 4 mg/mL INJECTION, SOLUTION	Fresenius	10 SYRINGE, GLASS in 1 CARTON (76045-005-1...	4 mg/mL	0.4	$7.57	—	● Active	PDAC
00409-1891-11	MORPHINE SULFATE (ISECURE SINGLE USE) 4 MG/ML	Unknown	—	—	0.4	$7.57	—	—	PDAC
00409-1135-02	MORPHINE SULFATE (HIGH CONCENTRATION,PF) 25 MG/ML	Unknown	—	—	2.5	$47.29	—	—	PDAC

NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

⚠️ Don't confuse J2274 with… RELATED CODES

Adjacent HCPCS codes that share an ingredient or formulation with J2274. Billing units and payment limits differ — confirm the exact code, strength and form before billing.

Code	Descriptor	Billing unit	Payment limit / unit	How it differs from J2274
J2270	Morphine sulfate injection	10 MG	$8.087	Related ingredient or formulation — confirm strength, form and billing unit before substituting.
J2272	Inj, morphine (fresenius)	10 MG	$8.455	Related ingredient or formulation — confirm strength, form and billing unit before substituting.

Related codes matched on shared ingredient (CMS Medicare Part B Spending feed). Billing units and payment limits from the CMS ASP Pricing File. Always verify the precise HCPCS code for the product and strength administered.

📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)

Period

Total Part B spend

$322.2K

Claims

657

Beneficiaries

469

Spend / beneficiary

$687.06

Spend / claim

$490.46

Trend by period

Where J2274 ranks among Part B drugs · 2026 (Q1) · neighbors ±5

Total spending — #484 of 824

#479 CYCLOPHOSPHAMIDE(J90... J9076 $332.9K #480 CIMERLI Q5128 $331.8K #481 MOZOBIL* J2562 $328.2K #482 NEOSTIM TL PER SQ CM... Q4265 $325.7K #483 COCOON MEMBRANE, PER... Q4264 $322.7K #484 DURAMORPH* J2274 $322.2K #485 THYMOGLOBULIN J7511 $320.5K #486 SHELTER DM MATRIX PE... Q4346 $318.9K #487 VISUDYNE J3396 $317.8K #488 AMBISOME* J0289 $311.8K #489 GRANIX J1447 $308.7K

Total claims — #422 of 824

#417 YONDELIS J9352 684 #418 ABILIFY MAINTENA J0401 670 #419 VIVITROL J2315 668 #420 METOPROLOL TARTRATE J0616 666 #421 ACAPATCH, PER SQ CM*... Q4325 661 #422 DURAMORPH* J2274 657 #423 KINEVAC* J2805 654 #424 CAREGRAFT, PER SQ CM... Q4322 652 #425 CORTROSYN* J0834 648 #426 ANKTIVA J9028 638 #427 THERASKIN** Q4121 637

Full breakdown by period (2)

Period	Total spend	Beneficiaries	Claims	$/beneficiary	$/claim
2026 (Q1)	$322.2K	469	657	$687.06	$490.46
2025 (Q1-Q4)	$1.1M	918	2,956	$1,201.32	$373.08

Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.

📈 Medicare Part B claims detail CMS PSPS · 2024

Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.

Allowed charges

$1.14M

Medicare paid

$869.1K

Submitted services

192,911

Denial rate

44.6%

Allowed / service

$10.63

Submitted charges

$4.13M

Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.

🗺️ Where J2274 is utilized CMS · BY PROVIDER · 2024

Medicare Part B services for this code by the rendering provider's state — 94,517 services across 12 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.

Hover or tap a state to see its numbers + top ZIP codes.

Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.

📊 What bills under J2274

J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.

NDC products by ingredient

Morphine Sulfate 15

morphine sulfate 4

MORPHINE SULFATE 3

NDC products by labeler

Hikma Pharmaceuticals USA Inc. 10

Hospira, Inc. 5

Fresenius Kabi, USA LLC 4

Piramal Critical Care, Inc. 2

Civica, Inc. 1

🔗 Related NDC directory pages

🧪 All Morphine Sulfate NDCsIngredient 🧪 All Morphine Sulfate NDCsIngredient 🧪 All Morphine Sulfate NDCsIngredient 🏭 All Hikma labeler NDCsLabeler 00641 🏭 All Hospira, labeler NDCsLabeler 00409 🏭 All Fresenius labeler NDCsLabeler 76045 🏭 All Piramal labeler NDCsLabeler 66794 📚 All Opioid Agonist NDCsDrug class

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.

HCPCS code & descriptor

CMS HCPCS Level II code file

Loaded

Payment limit & billing unit

CMS Medicare Part B ASP Pricing File (quarterly)

Q3 2026 · as of 2026-08-20

NDC ↔ HCPCS crosswalk

CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)

21 NDCs mapped

NADAC acquisition cost

CMS National Average Drug Acquisition Cost (weekly)

Available for mapped NDCs

Utilization & spend

CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners

Latest data year 2026

Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J2274 billing FAQ

What is HCPCS code J2274?

J2274 is a HCPCS Level II J-code used to bill Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg under Medicare Part B and most medical (not pharmacy) benefits.

What is the billing unit for J2274?

One unit of J2274 represents 10 MG. Report the number of units equal to the dose administered divided by 10 MG.

How many units of J2274 should I bill?

Divide the dose administered by the code's unit size (10 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.

How much does Medicare pay for J2274?

The Medicare Part B payment limit is $18.914 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $18.536 per unit. Payment limits are revised quarterly.

Which NDCs bill under J2274?

21 NDCs currently map to J2274 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.

Does a crosswalk mean J2274 is covered?

No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.

J2274 – Injection, morphine sulfate, preservative-free for epidural or intrathec · NDC Crosswalk & Billing Units