J2270
J2270 – Injection, morphine sulfate, up to 10 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 43 NDCs crosswalked per 10 MG $8.087/unit ASP+6%
📋 J2270 summary
J2270 is a HCPCS Level II J-code used to bill morphine sulfate, up to 10 mg, billed per 10 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Brand names associated with J2270: Morphine Sulfate(J2270)
Code J2270
Billing unit 10 MG Payment limit $8.087/unit NDC-Crosswalk 43
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ2270
DescriptorInjection, morphine sulfate, up to 10 mg
Billing unit10 MG
Payment limit / unit$8.087
Est. ASP / unit$7.629 est.
Mapped NDCs43
Data periodQ3 2026
Last updated2026-08-20
💊 About Morphine Injection DRUG GUIDE
Morphine sulfate injection is used to manage severe pain that requires an opioid analgesic and cannot be adequately controlled by other treatments.
It is only prescribed when other pain-relief options have failed or are not tolerated.Infumorph 200 and Infumorph 500 are specifically used for continuous epidural or intrathecal (spinal) delivery through a microinfusion device, for patients with severe chronic pain requiring long-term opioid management.
Duramorph is used for single-dose epidural or intrathecal bolus injections as well as standard intravenous or intramuscular use.
Clinical overview from our editorial drug guide for Morphine Injection. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$8.087
Est. ASP / unit
$7.629 est.
Est. after 2% sequester
$7.925
HCPCS dosage
10 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, morphine sulfate, up to 10 mg
CoverageD — Special coverage instructions apply
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment group—
Action codeN — No maintenance this year
Effective date1997-01-01
Date added1982-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J2270 = 10 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J2270 LEAST EXPENSIVE FIRST
43 NDCs map to J2270. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($8.087/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00409-1893-01 | Morphine Sulfate 10 mg/mL INJECTION, SOLUTION | Hospira, | 10 CARTRIDGE in 1 CARTON (0409-1893-01) /... | 10 mg/mL | 10 | $80.87 | $1.595 | Obsolete | CMS ASP |
| 00641-6125-25 | Morphine Sulfate 4 mg/mL INJECTION | Hikma | 25 VIAL, SINGLE-DOSE in 1 PACKAGE (0641-61... | 4 mg/mL | 10 | $80.87 | $2.313 | ● Active | CMS ASP |
| 00641-6127-25 | Morphine Sulfate 10 mg/mL INJECTION | Hikma | 25 VIAL, SINGLE-DOSE in 1 PACKAGE (0641-61... | 10 mg/mL | 25 | $202.18 | $2.342 | ● Active | CMS ASP |
| 00409-1134-03 | Morphine Sulfate | Pfizer | — | — | 100 | $808.70 | — | — | CMS + PDAC |
| 00409-1134-05 | Morphine Sulfate | Pfizer | — | — | 250 | $2,021.75 | — | — | CMS + PDAC |
| 00409-1890-01 | Morphine Sulfate 2 mg/mL INJECTION, SOLUTION | Hospira, | 10 CARTRIDGE in 1 CARTON (0409-1890-01) /... | 2 mg/mL | 2 | $16.17 | — | ● Active | CMS ASP |
| 00409-1890-23 | Morphine Sulfate 2 mg/mL INJECTION, SOLUTION | Hospira, | 10 SYRINGE in 1 CELLO PACK (0409-1890-23)... | 2 mg/mL | 2 | $16.17 | — | ● Active | CMS ASP |
| 00409-1891-01 | Morphine Sulfate 4 mg/mL INJECTION, SOLUTION | Hospira, | 10 CARTRIDGE in 1 CARTON (0409-1891-01) /... | 4 mg/mL | 4 | $32.35 | — | ● Active | CMS ASP |
| 00409-1891-23 | Morphine Sulfate 4 mg/mL INJECTION, SOLUTION | Hospira, | 10 SYRINGE in 1 CELLO PACK (0409-1891-23)... | 4 mg/mL | 4 | $32.35 | — | Obsolete | CMS ASP |
| 00409-1892-01 | Morphine Sulfate | Pfizer | — | — | 8 | $64.70 | — | — | CMS ASP |
| 00409-1893-23 | Morphine Sulfate 10 mg/mL INJECTION, SOLUTION | Hospira, | 10 SYRINGE in 1 CELLO PACK (0409-1893-23)... | 10 mg/mL | 10 | $80.87 | — | ● Active | CMS ASP |
| 00409-1896-20 | Morphine Sulfate 50 mg/mL INJECTION, SOLUTION | Hospira, | 1 VIAL, SINGLE-DOSE in 1 CARTON (0409-1896... | 50 mg/mL | 100 | $808.70 | — | ● Active | CMS ASP |
| 00409-2022-01 | Morphine sulfate 50 mg/mL INJECTION, SOLUTION | Hospira, | 1 VIAL, SINGLE-DOSE in 1 CARTON (0409-2022... | 50 mg/mL | 250 | $2,021.75 | — | ● Active | CMS ASP |
| 00641-6126-25 | Morphine Sulfate 8 mg/mL INJECTION | Hikma | 25 VIAL, SINGLE-DOSE in 1 PACKAGE (0641-61... | 8 mg/mL | 20 | $161.74 | — | ● Active | CMS ASP |
| 00641-6191-10 | Morphine Sulfate 2 mg/mL INJECTION | Hikma | 10 SYRINGE in 1 PACKAGE (0641-6191-10) /... | 2 mg/mL | 2 | $16.17 | — | ● Active | CMS ASP |
| 00641-6192-10 | Morphine Sulfate 4 mg/mL INJECTION | Hikma | 10 SYRINGE in 1 PACKAGE (0641-6192-10) /... | 4 mg/mL | 4 | $32.35 | — | ● Active | CMS ASP |
| 72572-0440-25 | Morphine Sulfate 4 mg/mL INJECTION | Civica, | 25 VIAL, SINGLE-DOSE in 1 PACKAGE (72572-4... | 4 mg/mL | 10 | $80.87 | — | ● Active | CMS ASP |
| 00406-1521-55 | Morphine Sulfate 1 kg/kg POWDER | SpecGx | .025 kg in 1 BOTTLE (0406-1521-55) | 1 kg/kg | 100 | $808.70 | — | ● Active | PDAC |
| 00406-1521-53 | Morphine Sulfate 1 kg/kg POWDER | SpecGx | .005 kg in 1 BOTTLE (0406-1521-53) | 1 kg/kg | 100 | $808.70 | — | ● Active | PDAC |
| 54868-4050-00 | MORPHINE SULFATE | Unknown | — | — | 100 | $808.70 | — | — | PDAC |
| 51927-1000-00 | MORPHINE SULFATE 1 g/g POWDER | Professional | 1 g in 1 CONTAINER (51927-1000-0) | 1 g/g | 100 | $808.70 | — | Obsolete | PDAC |
| 51552-0678-06 | MORPHINE SULFATE (1X100GM,USP) | Unknown | — | — | 100 | $808.70 | — | — | PDAC |
| 51552-0678-04 | MORPHINE SULFATE (1X25GM,USP) | Unknown | — | — | 100 | $808.70 | — | — | PDAC |
| 00406-1521-57 | Morphine Sulfate 1 kg/kg POWDER | SpecGx | .1 kg in 1 BOTTLE (0406-1521-57) | 1 kg/kg | 100 | $808.70 | — | ● Active | PDAC |
| 00406-1521-56 | Morphine Sulfate 1 kg/kg POWDER | SpecGx | .05 kg in 1 BOTTLE (0406-1521-56) | 1 kg/kg | 100 | $808.70 | — | ● Active | PDAC |
| 00409-6062-02 | MORPHINE SULFATE IN 5% DEXTROSE (PREMIX) 5%-100 MG/100 ML | Unknown | — | — | 0.1 | $0.81 | — | — | PDAC |
| 63323-0455-01 | MORPHINE SULFATE (PF,LATEX-FREE) 5 MG/1 ML | Unknown | — | — | 0.5 | $4.04 | — | — | PDAC |
| 63323-0454-01 | Morphine Sulfate 4 mg/mL INJECTION, SOLUTION | Fresenius | 25 VIAL, SINGLE-DOSE in 1 BOX (63323-454-0... | 4 mg/mL | 0.4 | $3.23 | — | ● Active | PDAC |
| 63323-0452-01 | Morphine Sulfate 2 mg/mL INJECTION, SOLUTION | Fresenius | 25 VIAL, SINGLE-DOSE in 1 BOX (63323-452-0... | 2 mg/mL | 0.2 | $1.62 | — | ● Active | PDAC |
| 63323-0451-01 | Morphine Sulfate 10 mg/mL INJECTION, SOLUTION | Fresenius | 25 VIAL, SINGLE-DOSE in 1 BOX (63323-451-0... | 10 mg/mL | 1 | $8.09 | — | ● Active | PDAC |
| 00409-6028-04 | MORPHINE SULFATE (SDV,30MLX10,PF) 5 MG/ML | Unknown | — | — | 0.5 | $4.04 | — | — | PDAC |
| 63275-1100-05 | MORPHINE SULFATE (U.S.P.) | Unknown | — | — | 100 | $808.70 | — | — | PDAC |
| 63275-1025-04 | MORPHINE SULFATE (U.S.P.) | Unknown | — | — | 100 | $808.70 | — | — | PDAC |
| 61553-0649-75 | MORPHINE SULFATE (5X50ML,LATEX-FREE) 50 MG/ML | Unknown | — | — | 5 | $40.44 | — | — | PDAC |
| 61553-0651-76 | MORPHINE SULFATE-SODIUM CHLORIDE (5X55ML,LATEX-FREE) 1 MG/ML-0.9% | Unknown | — | — | 0.1 | $0.81 | — | — | PDAC |
| 76329-1911-01 | MORPHINE SULFATE (USP, PUMP-JET) 1 MG/ML | Unknown | — | — | 0.1 | $0.81 | — | — | PDAC |
| 61553-0187-75 | DEXTROSE/MORPHINE SULFATE (SRN,60 ML) 5%-2 MG/ML | Unknown | — | — | 0.2 | $1.62 | — | — | PDAC |
| 61553-0186-67 | DEXTROSE/MORPHINE SULFATE (SRN,35 ML) 5%-2 MG/ML | Unknown | — | — | 0.2 | $1.62 | — | — | PDAC |
| 61553-0185-02 | DEXTROSE/MORPHINE SULFATE (INTRAVIA) 5%-100 MG/100 ML | Unknown | — | — | 0.1 | $0.81 | — | — | PDAC |
| 61553-0183-48 | DEXTROSE/MORPHINE SULFATE (INTRAVIA) 5%-100 MG/100 ML | Unknown | — | — | 0.1 | $0.81 | — | — | PDAC |
| 61553-0181-02 | MORPHINE SULFATE/SODIUM CHLORIDE (INTRAVIA) 250 MG/250 ML-0.9% | Unknown | — | — | 0.1 | $0.81 | — | — | PDAC |
| 61553-0179-48 | MORPHINE SULFATE/SODIUM CHLORIDE (INTRAVIA) 100 MG/100 ML-0.9% | Unknown | — | — | 0.1 | $0.81 | — | — | PDAC |
| 61553-0177-41 | MORPHINE SULFATE/SODIUM CHLORIDE (INTRAVIA) 50 MG/50 ML-0.9% | Unknown | — | — | 0.1 | $0.81 | — | — | PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)
Period
Total Part B spend
$8.2K
Claims
1,262
Beneficiaries
790
Spend / beneficiary
$10.38
Spend / claim
$6.50
Trend by period
Where J2270 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #693 of 824
#688
ALBUTEROL SULFATE(J7... J7612
$9.8K
#689
BRIXADI(J0577) J0577
$9.6K
#690
DEXTROSE IN WATER(J7... J7060
$9.4K
#691
CEFTAZIDIME* J0713
$9.3K
#692
BLEOMYCIN SULFATE J9040
$9.1K
#693
MORPHINE SULFATE(J22... J2270
$8.2K
#694
BUPIVACAINE HCL* J0665
$8.1K
#695
MIDAZOLAM HCL J2250
$8K
#696
PFIZER COVID (6M-4... 91318
$7.4K
#697
BORTEZOMIB(J9049) J9049
$6.9K
#698
ARGATROBAN-0.9% NACL... J0883
$6.7K
Total claims — #353 of 824
#348
HEMLIBRA J7170
1,352
#349
BAVENCIO J9023
1,352
#350
FIASP PUMPCART* J1811
1,343
#351
ALYGLO J1552
1,305
#352
DEXTROSE 5%-0.9% NAC... J7042
1,276
#353
MORPHINE SULFATE(J22... J2270
1,262
#354
RIMSO-50 J1212
1,256
#355
NIKTIMVO J9038
1,223
#356
NUZYRA J0121
1,197
#357
PULMOZYME J7639
1,187
#358
BELRAPZO* J9036
1,180
Top Medicare Part B drugs by the selected metric. Click any drug to open its J-code page. Source: CMS Medicare Quarterly Part B Spending by Drug.
Full breakdown by period (2)
| Period | Total spend | Beneficiaries | Claims | $/beneficiary | $/claim |
|---|---|---|---|---|---|
| 2026 (Q1) | $8.2K | 790 | 1,262 | $10.38 | $6.50 |
| 2025 (Q1-Q4) | $47.1K | 3,162 | 5,793 | $14.90 | $8.14 |
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$36.7K
Medicare paid
$31.8K
Submitted services
16,231
Denial rate
39.0%
Allowed / service
$3.71
Submitted charges
$768.5K
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
🗺️ Where J2270 is utilized CMS · BY PROVIDER · 2024
Medicare Part B services for this code by the rendering provider's state — 3,182 services across 6 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.
Hover or tap a state to see its numbers + top ZIP codes.
Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.
📊 What bills under J2270
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
43 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J2270 billing FAQ
What is HCPCS code J2270?
J2270 is a HCPCS Level II J-code used to bill Injection, morphine sulfate, up to 10 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J2270?
One unit of J2270 represents 10 MG. Report the number of units equal to the dose administered divided by 10 MG.
How many units of J2270 should I bill?
Divide the dose administered by the code's unit size (10 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J2270?
The Medicare Part B payment limit is $8.087 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $7.925 per unit. Payment limits are revised quarterly.
Which NDCs bill under J2270?
43 NDCs currently map to J2270 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J2270 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.