Morphine Injection

Generic name: Pronounced as (mor' feen)
Brand names
  • Astramorph® PF
  • Duramorph®
  • Infumorph®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 02/15/2021

Morphine injection may be habit forming, especially with prolonged use. Use morphine injection exactly as directed. Do not use more of it, use it more often, or use it in a different way than directed by your doctor. While you are using morphine, discuss with your health care provider your pain treatment goals, length of treatment, and other ways to manage your pain. Tell your doctor if you or anyone in your family drinks or has ever drunk large amounts of alcohol, uses or has ever used street drugs, or has overused prescription medications, or has had an overdose, or if you have or have ever had depression or another mental illness. There is a greater risk that you will overuse morphine if you have or have ever had any of these conditions. Talk to your health care provider immediately and ask for guidance if you think that you have an opioid addiction or call the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-HELP.

Morphine may cause serious or life-threatening breathing problems, especially during the first 24 to 72 hours of your treatment and any time your dose is increased. Your doctor will monitor you carefully during your treatment. Tell your doctor if you have or have ever had slowed breathing or asthma. Your doctor will probably tell you not to use morphine injection. Also tell your doctor if you have or have ever had lung disease such as chronic obstructive pulmonary disease (COPD; a group of diseases that affect the lungs and airways), a head injury, brain tumor, or any condition that increases the amount of pressure in your brain. The risk that you will develop breathing problems may be higher if you are an older adult or are weak or malnourished due to disease. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: slowed breathing, long pauses between breaths, or shortness of breath.

Taking certain medications during your treatment with morphine injection may increase the risk that you will experience serious or life-threatening breathing problems, sedation, or coma. Tell your doctor if you are taking or plan to take any of the following medications: benzodiazepines such as alprazolam (Xanax), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), and triazolam (Halcion); medications for mental illness nausea or pain; muscle relaxants; sedatives; sleeping pills; or tranquilizers. Your doctor may need to change the dosages of your medications and will monitor you carefully. If you use morphine injection with any of these medications and you develop any of the following symptoms, call your doctor immediately or seek emergency medical care: unusual dizziness, lightheadedness, extreme sleepiness, slowed or difficult breathing, or unresponsiveness. Be sure that your caregiver or family members know which symptoms may be serious so they can call the doctor or emergency medical care if you are unable to seek treatment on your own.

Drinking alcohol, taking prescription or nonprescription medications that contain alcohol, or using street drugs during your treatment with morphine injection increases the risk that you will experience these serious, life-threatening side effects. Do not drink alcohol, take prescription or nonprescription medications that contain alcohol, or use street drugs during your treatment.

Do not allow anyone else to use your medication. Morphine may harm or cause death to other people who use your medication, especially children.

Tell your doctor if you are pregnant or plan to become pregnant. If you use morphine regularly during your pregnancy, your baby may experience life-threatening withdrawal symptoms after birth. Tell your baby's doctor right away if your baby experiences any of the following symptoms: irritability, hyperactivity, abnormal sleep, high-pitched cry, uncontrollable shaking of a part of the body, vomiting, diarrhea, or failure to gain weight.

Talk to your doctor about the risks of using morphine injection.

Morphine injection is used to relieve moderate to severe pain. Morphine is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.

Morphine injection comes as a solution (liquid) to inject intramuscularly (into a muscle) or intravenously (into a vein). It is usually injected once every 4 hours as needed. Use morphine injection at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use morphine injection exactly as directed.

Your doctor may adjust your dose of morphine injection during your treatment, depending on how well your pain is controlled and on the side effects that you experience. Talk to your doctor about how you are feeling during your treatment with morphine injection.

If you have used morphine injection for longer than a few days, do not stop using it suddenly. If you suddenly stop using morphine injection, you may experience withdrawal symptoms including restlessness; teary eyes; runny nose; yawning; sweating; chills; muscle, back or joint pain; widening of the pupils; irritability; anxiety; weakness; stomach cramps; difficulty falling asleep or staying asleep; nausea; loss of appetite; vomiting; diarrhea; fast breathing; or fast heartbeat. Your doctor will probably decrease your dose gradually.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using morphine injection,

  • tell your doctor and pharmacist if you are allergic to morphine, any other medications, or ingredients in morphine injection. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antihistamines (found in cold and allergy medications); cimetidine (Tagamet); cyclobenzaprine (Amrix); lithium (Lithobid, in Librax); medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), and zolmitriptan (Zomig); mirtazapine (Remeron); 5HT3 serotonin blockers such as alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), ondansetron (Zofran, Zuplenz), or palonosetron (Aloxi); selective serotonin-reuptake inhibitors such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), and sertraline (Zoloft); serotonin and norepinephrine reuptake inhibitors such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor); tramadol (Conzip, Ultram, in Ultracet); trazodone; or tricyclic antidepressants ('mood elevators') such as amitriptyline, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor, Zonalon), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil). Also tell your doctor or pharmacist if you are taking or receiving the following monoamine oxidase (MAO) inhibitors or if you have stopped taking them within the past two weeks: isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). Many other medications may also interact with morphine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had any of the conditions mentioned in the IMPORTANT WARNING section or paralytic ileus (condition in which digested food does not move through the intestines). Your doctor may tell you not to use morphine.

  • tell your doctor what herbal products you are taking, especially St. John's wort.

  • tell your doctor if you have or have ever had low blood pressure, or heart, liver, or kidney disease.

  • tell your doctor if you are breastfeeding.

  • you should know that this medication may decrease fertility in men and women. Talk to your doctor about the risks of using morphine.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are using morphine.

  • you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

  • you should know that morphine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

  • you should know that morphine may cause constipation. Talk to your doctor about changing your diet or using other medications to prevent or treat constipation while you are using morphine.

Unless your doctor tells you otherwise, continue your normal diet.

  • Morphine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • headache

    • dizziness

    • lightheadedness

    • mood changes

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

    • seizures

    • slowed breathing

    • long pauses between breaths

    • shortness of breath

    • agitation, hallucinations (seeing things or hearing voices that do not exist), fever, sweating, confusion, fast heartbeat, shivering, severe muscle stiffness or twitching, loss of coordination, nausea, vomiting, or diarrhea

    • nausea, vomiting, loss of appetite, weakness, or dizziness

    • inability to get or keep an erection

    • irregular menstruation

    • decreased sexual desire

    • itching

    • rash

    • hives

  • Morphine may cause other side effects. Call your doctor if you have any unusual problems while you are using this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

While using morphine injection, you should talk to your doctor about having a rescue medication called naloxone readily available (e.g., home, office). Naloxone is used to reverse the life-threatening effects of an overdose. It works by blocking the effects of opiates to relieve dangerous symptoms caused by high levels of opiates in the blood. Your doctor may also prescribe you naloxone if you are living in a household where there are small children or someone who has abused street or prescription drugs. You should make sure that you and your family members, caregivers, or the people who spend time with you know how to recognize an overdose, how to use naloxone, and what to do until emergency medical help arrives. Your doctor or pharmacist will show you and your family members how to use the medication. Ask your pharmacist for the instructions or visit the manufacturer's website to get the instructions. If symptoms of an overdose occur, a friend or family member should give the first dose of naloxone, call 911 immediately, and stay with you and watch you closely until emergency medical help arrives. Your symptoms may return within a few minutes after you receive naloxone. If your symptoms return, the person should give you another dose of naloxone. Additional doses may be given every 2 to 3 minutes, if symptoms return before medical help arrives.

Symptoms of overdose may include the following:

  • slow, shallow, or irregular breathing

  • difficulty breathing

  • sleepiness

  • unable to respond or wake up

  • cold, clammy skin

  • small pupils

  • slow heartbeat

  • blurred vision

  • nausea

  • fainting

Keep all appointments with your doctor and laboratory. Your doctor may order certain lab tests to check your body's response to morphine.

Before having any laboratory test (especially those that involve methylene blue), tell your doctor and the laboratory personnel that you are using morphine.

This prescription is not refillable. If you are using morphine to control your pain on a long term basis, be sure to schedule appointments with your doctor so that you do not run out of medication. If you are using morphine on a short-term basis, call your doctor if you continue to experience pain after you finish the medication.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The metabolism of Repaglinide can be decreased when combined with Morphine.
Montelukast Montelukast The metabolism of Morphine can be decreased when combined with Montelukast.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Morphine.
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Morphine is combined with Dolasetron.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Morphine.
Candesartan Candesartan The metabolism of Morphine can be decreased when combined with Candesartan.
Clopidogrel Clopidogrel The serum concentration of the active metabolites of Clopidogrel can be decreased when Clopidogrel is used in combination with Morphine.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Morphine is combined with Diphenoxylate.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Morphine can be increased when it is combined with Erythromycin.
Fenofibrate Fenofibrate The metabolism of Morphine can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Morphine is combined with Guanfacine.
Magnesium Hydroxide Magnesium Hydroxide The therapeutic efficacy of Magnesium hydroxide can be decreased when used in combination with Morphine.
Magnesium Oxide Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Morphine.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Morphine is combined with Naratriptan.
Penbutolol Penbutolol The risk or severity of adverse effects can be increased when Morphine is combined with Acebutolol.
Pentazocine Pentazocine The therapeutic efficacy of Pentazocine can be decreased when used in combination with Morphine.
Polyethylene glycol-electrolyte solution (PEG-ES) Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Morphine.
Potassium Potassium The therapeutic efficacy of Potassium can be decreased when used in combination with Morphine.
Psyllium Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Morphine.
Reserpine Reserpine The serum concentration of Morphine can be increased when it is combined with Reserpine.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Morphine is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Morphine is combined with Sumatriptan.
Tacrolimus Tacrolimus The serum concentration of Morphine can be increased when it is combined with Tacrolimus.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Morphine is combined with Tizanidine.
Zolmitriptan Zolmitriptan The risk or severity of adverse effects can be increased when Morphine is combined with Zolmitriptan.
Fluconazole Injection Fluconazole Injection The serum concentration of Morphine can be increased when it is combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Morphine is combined with Hydromorphone.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Meperidine.
Metoclopramide Injection Metoclopramide Injection The therapeutic efficacy of Morphine can be decreased when used in combination with Metoclopramide.
Metronidazole Injection Metronidazole Injection The metabolism of Morphine can be decreased when combined with Metronidazole.
Zidovudine Injection Zidovudine Injection The metabolism of Morphine can be increased when combined with Zidovudine.
Altretamine Altretamine Amphetamine may increase the analgesic activities of Morphine.
Cyclosporine Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Morphine.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Morphine is combined with Ondansetron.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Morphine is combined with Granisetron.
Torsemide Torsemide The metabolism of Morphine can be decreased when combined with Torasemide.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Morphine is combined with Olanzapine.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Morphine is combined with Alosetron.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Morphine is combined with Entacapone.
Eprosartan Eprosartan The risk or severity of adverse effects can be increased when Morphine is combined with Eprosartan.
Hydroxychloroquine Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Morphine.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Morphine is combined with Oxcarbazepine.
Telmisartan Telmisartan The risk or severity of adverse effects can be increased when Morphine is combined with Telmisartan.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Morphine is combined with Zaleplon.
Anakinra Anakinra The metabolism of Morphine can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Morphine is combined with Desloratadine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Morphine.
Trimipramine Trimipramine The risk or severity of adverse effects can be increased when Morphine is combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Morphine can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate The risk or severity of adverse effects can be increased when Morphine is combined with Glycopyrronium.
Perindopril Perindopril The risk or severity of adverse effects can be increased when Morphine is combined with Perindopril.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Morphine.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Morphine.
Eplerenone Eplerenone The therapeutic efficacy of Eplerenone can be decreased when used in combination with Morphine.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Morphine is combined with Escitalopram.
Olmesartan Olmesartan The risk or severity of adverse effects can be increased when Morphine is combined with Olmesartan.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Morphine is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Morphine can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The risk or severity of adverse effects can be increased when Morphine is combined with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Morphine.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Morphine is combined with Dexmethylphenidate.
Atazanavir Atazanavir The metabolism of Morphine can be decreased when combined with Atazanavir.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Morphine.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Morphine.
Polyethylene Glycol 3350 Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Morphine.
Vardenafil Vardenafil The serum concentration of Vardenafil can be increased when it is combined with Morphine.
Tegaserod Tegaserod The serum concentration of Tegaserod can be increased when it is combined with Morphine.
Tadalafil Tadalafil Morphine may increase the hypotensive activities of Tadalafil.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Morphine is combined with Frovatriptan.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Apomorphine.
Infliximab Injection Infliximab Injection The metabolism of Morphine can be increased when combined with Infliximab.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Morphine is combined with Protriptyline.
Rifaximin Rifaximin The metabolism of Morphine can be increased when combined with Rifaximin.
Duloxetine Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Morphine is combined with Duloxetine.
Trospium Trospium The risk or severity of adverse effects can be increased when Morphine is combined with Trospium.
Bosentan Bosentan Morphine may increase the hypotensive activities of Bosentan.
Erlotinib Erlotinib The metabolism of Morphine can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Morphine is combined with Eszopiclone.
Solifenacin Solifenacin The risk or severity of adverse effects can be increased when Morphine is combined with Solifenacin.
Dextroamphetamine Dextroamphetamine Amphetamine may increase the analgesic activities of Morphine.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Isocarboxazid Isocarboxazid Isocarboxazid may increase the analgesic activities of Morphine.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Morphine is combined with Ramelteon.
Darifenacin Darifenacin The risk or severity of adverse effects can be increased when Darifenacin is combined with Morphine.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Morphine is combined with Fentanyl.
Pregabalin Pregabalin The therapeutic efficacy of Morphine can be increased when used in combination with Pregabalin.
Deferasirox Deferasirox The metabolism of Morphine can be decreased when combined with Deferasirox.
Tipranavir Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Morphine.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Morphine is combined with Felbamate.
Ranolazine Ranolazine The serum concentration of Morphine can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Morphine can be increased when combined with Abatacept.
Rasagiline Rasagiline Rasagiline may increase the analgesic activities of Morphine.
Imatinib Imatinib The metabolism of Imatinib can be decreased when combined with Morphine.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Morphine.
Paliperidone Paliperidone The serum concentration of Morphine can be increased when it is combined with Paliperidone.
Bortezomib Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Morphine.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Clofarabine.
Lubiprostone Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Morphine.
Posaconazole Posaconazole The serum concentration of Posaconazole can be increased when it is combined with Morphine.
Aliskiren Aliskiren The risk or severity of adverse effects can be increased when Morphine is combined with Aliskiren.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Morphine is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine Lisdexamfetamine may increase the analgesic activities of Morphine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Sorafenib Sorafenib The metabolism of Morphine can be decreased when combined with Sorafenib.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Lapatinib Lapatinib The serum concentration of Morphine can be increased when it is combined with Lapatinib.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Morphine is combined with Levocetirizine.
Dasatinib Dasatinib The serum concentration of Dasatinib can be increased when it is combined with Morphine.
Paclitaxel (with polyoxyethylated castor oil) Injection Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Morphine.
Temsirolimus Temsirolimus The serum concentration of Temsirolimus can be increased when it is combined with Morphine.
Nilotinib Nilotinib The serum concentration of Morphine can be increased when it is combined with Nilotinib.
Toremifene Toremifene The serum concentration of Morphine can be increased when it is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Morphine can be decreased when combined with Bexarotene.
Desmopressin Desmopressin The risk or severity of hyponatremia can be increased when Morphine is combined with Desmopressin.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Morphine.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Morphine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Morphine is combined with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Morphine is combined with Desvenlafaxine.
Nebivolol Nebivolol The risk or severity of adverse effects can be increased when Morphine is combined with Nebivolol.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Morphine.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Morphine.
Certolizumab Injection Certolizumab Injection The metabolism of Morphine can be increased when combined with Certolizumab pegol.
Alvimopan Alvimopan The risk or severity of adverse effects can be increased when Morphine is combined with Alvimopan.
Methylnaltrexone Injection Methylnaltrexone Injection The therapeutic efficacy of Morphine can be decreased when used in combination with Methylnaltrexone.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Morphine.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Morphine.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Morphine is combined with Midazolam.
Eltrombopag Eltrombopag The metabolism of Morphine can be decreased when combined with Eltrombopag.
Milnacipran Milnacipran The risk or severity of serotonin syndrome can be increased when Morphine is combined with Milnacipran.
Sodium Phosphate Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Morphine.
Fesoterodine Fesoterodine The risk or severity of adverse effects can be increased when Morphine is combined with Fesoterodine.
Betaxolol Betaxolol The risk or severity of adverse effects can be increased when Morphine is combined with Betaxolol.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Morphine is combined with Iloperidone.
Prasugrel Prasugrel The serum concentration of the active metabolites of Prasugrel can be reduced when Prasugrel is used in combination with Morphine resulting in a loss in efficacy.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Morphine is combined with Lacosamide.
Everolimus Everolimus The serum concentration of Everolimus can be increased when it is combined with Morphine.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Morphine.
Dronedarone Dronedarone The serum concentration of Dronedarone can be increased when it is combined with Morphine.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Morphine.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Morphine is combined with Palonosetron.
Romidepsin Injection Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Morphine.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Topotecan Topotecan The serum concentration of Topotecan can be increased when it is combined with Morphine.
Golimumab Injection Golimumab Injection The metabolism of Morphine can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Morphine can be decreased when combined with Pazopanib.
Asenapine Asenapine The risk or severity of adverse effects can be increased when Morphine is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Morphine is combined with Vigabatrin.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Morphine.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Morphine is combined with Oxymorphone.
Tocilizumab Injection Tocilizumab Injection The metabolism of Morphine can be increased when combined with Tocilizumab.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Morphine.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Morphine.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Morphine is combined with Lurasidone.
Vilazodone Vilazodone The risk or severity of adverse effects can be increased when Morphine is combined with Vilazodone.
Denileukin Diftitox Injection Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Morphine.
Azilsartan Azilsartan The risk or severity of adverse effects can be increased when Morphine is combined with Azilsartan medoxomil.
Linagliptin Linagliptin The serum concentration of Morphine can be increased when it is combined with Linagliptin.
Telaprevir Telaprevir The metabolism of Morphine can be decreased when combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Morphine can be increased when combined with Cyclophosphamide.
Abiraterone Abiraterone The metabolism of Morphine can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Morphine.
Ticagrelor Ticagrelor The therapeutic efficacy of Ticagrelor can be decreased when used in combination with Morphine.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Morphine.
Vandetanib Vandetanib The serum concentration of Morphine can be increased when it is combined with Vandetanib.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Morphine is combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Morphine can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Morphine can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The serum concentration of Morphine can be increased when it is combined with Ivacaftor.
Axitinib Axitinib The serum concentration of Axitinib can be increased when it is combined with Morphine.
Crizotinib Crizotinib The serum concentration of Morphine can be increased when it is combined with Crizotinib.
Cabergoline Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Morphine.
Naloxone Injection Naloxone Injection The therapeutic efficacy of Morphine can be decreased when used in combination with Naloxone.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Morphine.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Morphine is combined with Tiagabine.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Morphine can be increased when it is combined with Carfilzomib.
Iloprost Iloprost The risk or severity of adverse effects can be increased when Morphine is combined with Iloprost.
Enzalutamide Enzalutamide The serum concentration of Morphine can be increased when it is combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Morphine.
Regorafenib Regorafenib The metabolism of Morphine can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Morphine can be decreased when combined with Bosutinib.
Linaclotide Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Morphine.
Teriflunomide Teriflunomide The metabolism of Morphine can be decreased when combined with Teriflunomide.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Morphine can be decreased when combined with Cabozantinib.
Ponatinib Ponatinib The metabolism of Morphine can be decreased when combined with Ponatinib.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Morphine is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Trastuzumab emtansine can be increased when it is combined with Morphine.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Morphine.
Canagliflozin Canagliflozin The serum concentration of Morphine can be increased when it is combined with Canagliflozin.
Methazolamide Methazolamide The therapeutic efficacy of Methazolamide can be decreased when used in combination with Morphine.
Dabrafenib Dabrafenib The metabolism of Morphine can be decreased when combined with Dabrafenib.
Trametinib Trametinib The metabolism of Morphine can be decreased when combined with Trametinib.
Dolutegravir Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Morphine.
Afatinib Afatinib The serum concentration of Morphine can be increased when it is combined with Afatinib.
Levomilnacipran Levomilnacipran The risk or severity of serotonin syndrome can be increased when Morphine is combined with Levomilnacipran.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Morphine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Lomitapide Lomitapide The serum concentration of Lomitapide can be increased when it is combined with Morphine.
Avanafil Avanafil The risk or severity of hypotension can be increased when Avanafil is combined with Morphine.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Morphine.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Morphine is combined with Obinutuzumab.
Simeprevir Simeprevir The serum concentration of Morphine can be increased when it is combined with Simeprevir.
Sofosbuvir Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Morphine.
Dapagliflozin Dapagliflozin The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Morphine.
Apremilast Apremilast The metabolism of Morphine can be increased when combined with Apremilast.
Ceritinib Ceritinib The serum concentration of Ceritinib can be increased when it is combined with Morphine.
Siltuximab Injection Siltuximab Injection The metabolism of Morphine can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Morphine is combined with Eslicarbazepine.
Belinostat Injection Belinostat Injection The serum concentration of Belinostat can be increased when it is combined with Morphine.
Idelalisib Idelalisib The serum concentration of Idelalisib can be increased when it is combined with Morphine.
Empagliflozin Empagliflozin The risk or severity of adverse effects can be increased when Morphine is combined with Empagliflozin.
Vorapaxar Vorapaxar The serum concentration of Morphine can be increased when it is combined with Vorapaxar.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Suvorexant Suvorexant Morphine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Morphine.
Methamphetamine Methamphetamine Metamfetamine may increase the analgesic activities of Morphine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Morphine is combined with Tasimelteon.
Riociguat Riociguat The metabolism of Riociguat can be decreased when combined with Morphine.
Nintedanib Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Morphine.
Secukinumab Injection Secukinumab Injection The metabolism of Morphine can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection Morphine may increase the hypotensive activities of Risperidone.
Palbociclib Palbociclib The serum concentration of Morphine can be increased when it is combined with Palbociclib.
Lenvatinib Lenvatinib The metabolism of Morphine can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The therapeutic efficacy of Morphine can be decreased when used in combination with Naloxegol.
Panobinostat Panobinostat The serum concentration of Panobinostat can be increased when it is combined with Morphine.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Morphine is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Morphine is combined with Haloperidol.
Amiloride Amiloride The therapeutic efficacy of Amiloride can be decreased when used in combination with Morphine.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Morphine can be increased when it is combined with Isavuconazonium.
Macitentan Macitentan Morphine may increase the hypotensive activities of Macitentan.
Flibanserin Flibanserin The serum concentration of Morphine can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The serum concentration of Morphine can be increased when it is combined with Rolapitant.
Daclatasvir Daclatasvir The serum concentration of Morphine can be increased when it is combined with Daclatasvir.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Morphine is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Morphine.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Morphine is combined with Cariprazine.
Eluxadoline Eluxadoline The risk or severity of constipation can be increased when Morphine is combined with Eluxadoline.
Cobimetinib Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Morphine.
Osimertinib Osimertinib The serum concentration of Osimertinib can be increased when it is combined with Morphine.
Rifapentine Rifapentine The metabolism of Morphine can be increased when combined with Rifapentine.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The risk or severity of adverse effects can be increased when Morphine is combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Morphine can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Morphine is combined with Brivaracetam.
Venetoclax Venetoclax The serum concentration of Morphine can be increased when it is combined with Venetoclax.
Cobicistat Cobicistat The serum concentration of Morphine can be increased when it is combined with Cobicistat.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Morphine.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Morphine is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Diphenhydramine.
Furosemide Injection Furosemide Injection The therapeutic efficacy of Furosemide can be decreased when used in combination with Morphine.
Rucaparib Rucaparib The metabolism of Morphine can be decreased when combined with Rucaparib.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Morphine.
Doxepin (Insomnia) Doxepin (Insomnia) The risk or severity of adverse effects can be increased when Morphine is combined with Doxepin.
Plecanatide Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Morphine.
Safinamide Safinamide Safinamide may increase the analgesic activities of Morphine.
Naldemedine Naldemedine The therapeutic efficacy of Morphine can be decreased when used in combination with Naldemedine.
Midostaurin Midostaurin The metabolism of Morphine can be decreased when combined with Midostaurin.
Neratinib Neratinib The serum concentration of Morphine can be increased when it is combined with Neratinib.
Enasidenib Enasidenib The metabolism of Morphine can be decreased when combined with Enasidenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Morphine.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Morphine.
Abemaciclib Abemaciclib The serum concentration of Abemaciclib can be increased when it is combined with Morphine.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Morphine.
Letermovir Letermovir The metabolism of Morphine can be decreased when combined with Letermovir.
Ertugliflozin Ertugliflozin The metabolism of Morphine can be decreased when combined with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection Morphine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide The serum concentration of Morphine can be decreased when it is combined with Apalutamide.
Fostamatinib Fostamatinib The metabolism of Morphine can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Morphine.
Baricitinib Baricitinib The serum concentration of Baricitinib can be increased when it is combined with Morphine.
Lofexidine Lofexidine The therapeutic efficacy of Morphine can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The serum concentration of Eliglustat can be increased when it is combined with Morphine.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Morphine.
Ivosidenib Ivosidenib The serum concentration of Morphine can be increased when it is combined with Ivosidenib.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Morphine.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Morphine.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Morphine.
Dacomitinib Dacomitinib The serum concentration of Dacomitinib can be increased when it is combined with Morphine.
Duvelisib Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Morphine.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Morphine.
Sarecycline Sarecycline The serum concentration of Morphine can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Morphine is combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Morphine.
Gilteritinib Gilteritinib The serum concentration of Gilteritinib can be increased when it is combined with Morphine.
Glasdegib Glasdegib The serum concentration of Morphine can be increased when it is combined with Glasdegib.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Morphine.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Morphine.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Morphine.
Rifamycin Rifamycin The serum concentration of Morphine can be increased when it is combined with Rifamycin.
Prucalopride Prucalopride The therapeutic efficacy of Prucalopride can be decreased when used in combination with Morphine.
Magnesium Citrate Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Morphine.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Morphine can be increased when combined with Emapalumab.
Erdafitinib Erdafitinib The serum concentration of Morphine can be increased when it is combined with Erdafitinib.
Alpelisib Alpelisib The metabolism of Morphine can be decreased when combined with Alpelisib.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Morphine is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Morphine is combined with Solriamfetol.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Morphine.
Triclabendazole Triclabendazole The metabolism of Morphine can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The serum concentration of Morphine can be increased when it is combined with Entrectinib.
Pexidartinib Pexidartinib The metabolism of Morphine can be decreased when combined with Pexidartinib.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Morphine.
Pitolisant Pitolisant The serum concentration of Morphine can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The serum concentration of Morphine can be increased when it is combined with Fedratinib.
Lefamulin Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Morphine.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Morphine.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Morphine.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Morphine.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Morphine is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Morphine is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Morphine.
Tazemetostat Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Morphine.
Cenobamate Cenobamate The serum concentration of Morphine can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The metabolism of Ozanimod can be decreased when combined with Morphine.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Morphine.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Morphine.
Tucatinib Tucatinib Morphine may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Morphine.
Ripretinib Ripretinib The serum concentration of Morphine can be increased when it is combined with Ripretinib.
Selpercatinib Selpercatinib The serum concentration of Morphine can be increased when it is combined with Selpercatinib.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Morphine is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Morphine is combined with Fenfluramine.
Fostemsavir Fostemsavir The serum concentration of Fostemsavir can be increased when it is combined with Morphine.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Morphine.
Pralsetinib Pralsetinib The serum concentration of Morphine can be increased when it is combined with Pralsetinib.
Opicapone Opicapone The metabolism of Morphine can be decreased when combined with Opicapone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Morphine can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The therapeutic efficacy of Drospirenone can be decreased when used in combination with Morphine.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Morphine is combined with Viloxazine.
Theophylline Theophylline The metabolism of Morphine can be decreased when combined with Theophylline.
Indomethacin Indomethacin The metabolism of Morphine can be decreased when combined with Indomethacin.
Mefenamic Acid Mefenamic Acid The metabolism of Morphine can be decreased when combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Morphine.
Trazodone Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Morphine.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Phenobarbital is combined with Morphine.
Metaxalone Metaxalone The risk or severity of respiratory depression can be increased when Morphine is combined with Metaxalone.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Morphine is combined with Levorphanol.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Morphine.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Morphine is combined with Methsuximide.
Diethylpropion Diethylpropion Diethylpropion may increase the analgesic activities of Morphine.
Chlorpromazine Chlorpromazine The risk or severity of adverse effects can be increased when Chlorpromazine is combined with Morphine.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Morphine is combined with Diazepam.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Morphine is combined with Oxazepam.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Morphine is combined with Flurazepam.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Morphine is combined with Clorazepic acid.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Morphine is combined with Lorazepam.
Phenoxybenzamine Phenoxybenzamine The risk or severity of adverse effects can be increased when Morphine is combined with Phenoxybenzamine.
Amantadine Amantadine The risk or severity of adverse effects can be increased when Morphine is combined with Amantadine.
Codeine Codeine The risk or severity of adverse effects can be increased when Morphine is combined with Codeine.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Morphine is combined with Meprobamate.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Morphine is combined with Chlordiazepoxide.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Morphine is combined with Bromocriptine.
Tranylcypromine Tranylcypromine Tranylcypromine may increase the analgesic activities of Morphine.
Phenelzine Phenelzine Phenelzine may increase the analgesic activities of Morphine.
Procarbazine Procarbazine Procarbazine may increase the analgesic activities of Morphine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Morphine is combined with Ergoloid mesylate.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Prochlorperazine Prochlorperazine The risk or severity of hypotension and CNS depression can be increased when Prochlorperazine is combined with Morphine.
Thioridazine Thioridazine The risk or severity of adverse effects can be increased when Morphine is combined with Thioridazine.
Trifluoperazine Trifluoperazine The risk or severity of hypotension and CNS depression can be increased when Trifluoperazine is combined with Morphine.
Dapsone Dapsone The metabolism of Morphine can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Morphine.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Morphine is combined with Oxycodone.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Morphine.
Oxybutynin Oxybutynin The risk or severity of adverse effects can be increased when Oxybutynin is combined with Morphine.
Benztropine Benztropine The risk or severity of adverse effects can be increased when Morphine is combined with Benzatropine.
Maprotiline Maprotiline The risk or severity of adverse effects can be increased when Morphine is combined with Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Morphine.
Trihexyphenidyl Trihexyphenidyl The risk or severity of adverse effects can be increased when Morphine is combined with Trihexyphenidyl.
Orphenadrine Orphenadrine Morphine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Morphine.
Fluphenazine Fluphenazine The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Morphine.
Phentermine Phentermine Phentermine may increase the analgesic activities of Morphine.
Amoxapine Amoxapine The risk or severity of adverse effects can be increased when Amoxapine is combined with Morphine.
Hydrocortisone Hydrocortisone The metabolism of Morphine can be increased when combined with Hydrocortisone.
Dactinomycin Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Morphine.
Carbamazepine Carbamazepine The risk or severity of adverse effects can be increased when Morphine is combined with Carbamazepine.
Molindone Molindone The risk or severity of adverse effects can be increased when Morphine is combined with Molindone.
Methyldopa Methyldopa The risk or severity of adverse effects can be increased when Morphine is combined with Methyldopa.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Morphine.
Prazosin Prazosin The risk or severity of adverse effects can be increased when Morphine is combined with Prazosin.
Hydralazine Hydralazine The risk or severity of adverse effects can be increased when Morphine is combined with Hydralazine.
Cimetidine Cimetidine The risk or severity of adverse effects can be increased when Cimetidine is combined with Morphine.
Warfarin Warfarin The metabolism of Morphine can be decreased when combined with Warfarin.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Morphine is combined with Clonazepam.
Loperamide Loperamide The serum concentration of Loperamide can be increased when it is combined with Morphine.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Promethazine is combined with Morphine.
Griseofulvin Griseofulvin The metabolism of Morphine can be increased when combined with Griseofulvin.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Morphine.
Loxapine Loxapine The serum concentration of Morphine can be increased when it is combined with Loxapine.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Morphine.
Quinine Quinine The serum concentration of Morphine can be increased when it is combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Morphine is combined with Ethosuximide.
Triamterene Triamterene The therapeutic efficacy of Triamterene can be decreased when used in combination with Morphine.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Morphine.
Sulfinpyrazone Sulfinpyrazone The metabolism of Morphine can be decreased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The therapeutic efficacy of Chlorothiazide can be decreased when used in combination with Morphine.
Chlorthalidone Chlorthalidone The therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Morphine.
Metolazone Metolazone The therapeutic efficacy of Metolazone can be decreased when used in combination with Morphine.
Isosorbide Isosorbide The therapeutic efficacy of Isosorbide can be decreased when used in combination with Morphine.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Morphine.
Desipramine Desipramine The risk or severity of adverse effects can be increased when Morphine is combined with Desipramine.
Amitriptyline Amitriptyline The risk or severity of adverse effects can be increased when Morphine is combined with Amitriptyline.
Imipramine Imipramine The risk or severity of adverse effects can be increased when Morphine is combined with Imipramine.
Probenecid Probenecid The metabolism of Morphine can be decreased when combined with Probenecid.
Quinidine Quinidine The risk or severity of adverse effects can be increased when Morphine is combined with Quinidine.
Isoniazid Isoniazid The risk or severity of serotonin syndrome can be increased when Morphine is combined with Isoniazid.
Rifampin Rifampin The metabolism of Morphine can be increased when combined with Rifampicin.
Disopyramide Disopyramide The risk or severity of adverse effects can be increased when Morphine is combined with Disopyramide.
Valproic Acid Valproic Acid The metabolism of Morphine can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The serum concentration of Morphine can be increased when it is combined with Tamoxifen.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Morphine.
Levothyroxine Levothyroxine The metabolism of Morphine can be decreased when combined with Levothyroxine.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Morphine.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Morphine is combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Morphine is combined with Cyclobenzaprine.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Morphine.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Cyproheptadine Cyproheptadine The risk or severity of adverse effects can be increased when Morphine is combined with Cyproheptadine.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Morphine.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Morphine is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Morphine is combined with Brompheniramine.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Morphine is combined with Meclizine.
Methyclothiazide Methyclothiazide The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Morphine.
Hydrochlorothiazide Hydrochlorothiazide The therapeutic efficacy of Hydrochlorothiazide can be decreased when used in combination with Morphine.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Morphine is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Morphine is combined with Chlorzoxazone.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Morphine.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Morphine is combined with Methocarbamol.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The risk or severity of adverse effects can be increased when Morphine is combined with Propranolol.
Minoxidil Minoxidil The risk or severity of adverse effects can be increased when Morphine is combined with Minoxidil.
Pseudoephedrine Pseudoephedrine Pseudoephedrine may increase the analgesic activities of Morphine.
Nortriptyline Nortriptyline The risk or severity of adverse effects can be increased when Morphine is combined with Nortriptyline.
Spironolactone Spironolactone The metabolism of Morphine can be decreased when combined with Spironolactone.
Amphotericin B Injection Amphotericin B Injection The risk or severity of adverse effects can be increased when Morphine is combined with Amphotericin B.
Nadolol Nadolol The risk or severity of adverse effects can be increased when Morphine is combined with Nadolol.
Butorphanol Injection Butorphanol Injection The therapeutic efficacy of Butorphanol can be decreased when used in combination with Morphine.
Nalbuphine Injection Nalbuphine Injection The therapeutic efficacy of Nalbuphine can be decreased when used in combination with Morphine.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Morphine is combined with Trimethobenzamide.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Morphine.
Flavoxate Flavoxate The risk or severity of adverse effects can be increased when Morphine is combined with Flavoxate.
Papaverine Papaverine The risk or severity of adverse effects can be increased when Morphine is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Morphine.
Colchicine Colchicine The metabolism of Morphine can be decreased when combined with Colchicine.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Morphine is combined with Acetazolamide.
Ketoconazole Ketoconazole The serum concentration of Morphine can be increased when it is combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Morphine is combined with Pyrantel.
Vincristine Injection Vincristine Injection The serum concentration of Vincristine can be increased when it is combined with Morphine.
Captopril Captopril The risk or severity of adverse effects can be increased when Morphine is combined with Captopril.
Dipyridamole Dipyridamole The risk or severity of adverse effects can be increased when Morphine is combined with Dipyridamole.
Isoxsuprine Isoxsuprine The risk or severity of adverse effects can be increased when Morphine is combined with Isoxsuprine.
Vinblastine Vinblastine The serum concentration of Vinblastine can be increased when it is combined with Morphine.
Ethacrynic Acid Ethacrynic Acid The therapeutic efficacy of Etacrynic acid can be decreased when used in combination with Morphine.
Metoprolol Metoprolol The risk or severity of adverse effects can be increased when Morphine is combined with Metoprolol.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Morphine.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Morphine is combined with Thiothixene.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Morphine is combined with Alprazolam.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Morphine is combined with Temazepam.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Morphine is combined with Triazolam.
Dicyclomine Dicyclomine The risk or severity of adverse effects can be increased when Morphine is combined with Dicyclomine.
Hyoscyamine Hyoscyamine The risk or severity of adverse effects can be increased when Morphine is combined with Hyoscyamine.
Propantheline Propantheline The risk or severity of adverse effects can be increased when Morphine is combined with Propantheline.
Trimethoprim Trimethoprim The metabolism of Morphine can be decreased when combined with Trimethoprim.
Diltiazem Diltiazem The metabolism of Morphine can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Morphine can be decreased when combined with Nifedipine.
Timolol Timolol The risk or severity of adverse effects can be increased when Morphine is combined with Timolol.
Verapamil Verapamil The serum concentration of Morphine can be increased when it is combined with Verapamil.
Atenolol Atenolol The risk or severity of adverse effects can be increased when Morphine is combined with Atenolol.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Morphine is combined with Pindolol.
Piroxicam Piroxicam The metabolism of Morphine can be decreased when combined with Piroxicam.
Bumetanide Bumetanide The therapeutic efficacy of Bumetanide can be decreased when used in combination with Morphine.
Etoposide Etoposide The serum concentration of Etoposide can be increased when it is combined with Morphine.
Indapamide Indapamide The therapeutic efficacy of Indapamide can be decreased when used in combination with Morphine.
Pentoxifylline Pentoxifylline The risk or severity of hypotension can be increased when Pentoxifylline is combined with Morphine.
Labetalol Labetalol The risk or severity of adverse effects can be increased when Morphine is combined with Labetalol.
Gemfibrozil Gemfibrozil The metabolism of Morphine can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz Morphine may increase the hypotensive activities of Guanabenz.
Ketoprofen Ketoprofen The metabolism of Morphine can be decreased when combined with Ketoprofen.
Pimozide Pimozide The risk or severity of adverse effects can be increased when Morphine is combined with Pimozide.
Enalapril Enalapril The risk or severity of adverse effects can be increased when Morphine is combined with Enalapril.
Flurbiprofen Flurbiprofen The metabolism of Morphine can be decreased when combined with Flurbiprofen.
Amiodarone Amiodarone The metabolism of Amiodarone can be decreased when combined with Morphine.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Morphine is combined with Buspirone.
Lovastatin Lovastatin The metabolism of Morphine can be decreased when combined with Lovastatin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Morphine.
Fluoxetine Fluoxetine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Morphine.
Nimodipine Nimodipine The risk or severity of adverse effects can be increased when Morphine is combined with Nimodipine.
Clozapine Clozapine The risk or severity of adverse effects can be increased when Morphine is combined with Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Morphine is combined with Estazolam.
Clarithromycin Clarithromycin The serum concentration of Morphine can be increased when it is combined with Clarithromycin.
Benazepril Benazepril The risk or severity of adverse effects can be increased when Morphine is combined with Benazepril.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Morphine.
Fosinopril Fosinopril The risk or severity of adverse effects can be increased when Morphine is combined with Fosinopril.
Pravastatin Pravastatin The serum concentration of Morphine can be increased when it is combined with Pravastatin.
Quinapril Quinapril The risk or severity of adverse effects can be increased when Morphine is combined with Quinapril.
Ramipril Ramipril The risk or severity of adverse effects can be increased when Morphine is combined with Ramipril.
Simvastatin Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Morphine.
Amlodipine Amlodipine The risk or severity of adverse effects can be increased when Morphine is combined with Amlodipine.
Itraconazole Itraconazole The serum concentration of Morphine can be increased when it is combined with Itraconazole.
Lisinopril Lisinopril The risk or severity of adverse effects can be increased when Morphine is combined with Lisinopril.
Rifabutin Rifabutin The metabolism of Morphine can be increased when combined with Rifabutin.
Sotalol Sotalol The risk or severity of adverse effects can be increased when Morphine is combined with Sotalol.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Morphine.
Zolpidem Zolpidem Morphine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin The risk or severity of adverse effects can be increased when Morphine is combined with Doxazosin.
Terazosin Terazosin The risk or severity of adverse effects can be increased when Morphine is combined with Terazosin.
Isradipine Isradipine The risk or severity of adverse effects can be increased when Morphine is combined with Isradipine.
Omeprazole Omeprazole The metabolism of Omeprazole can be decreased when combined with Morphine.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Morphine.
Gabapentin Gabapentin The serum concentration of Gabapentin can be increased when it is combined with Morphine.
Fluvastatin Fluvastatin The metabolism of Morphine can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Morphine.
Fluvoxamine Fluvoxamine The risk or severity of serotonin syndrome can be increased when Morphine is combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of serotonin syndrome can be increased when Nefazodone is combined with Morphine.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Morphine.
Losartan Losartan The metabolism of Morphine can be decreased when combined with Losartan.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Morphine.
Moexipril Moexipril The risk or severity of adverse effects can be increased when Morphine is combined with Moexipril.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Morphine.
Ifosfamide Injection Ifosfamide Injection The metabolism of Morphine can be increased when combined with Ifosfamide.
Nicardipine Nicardipine The risk or severity of adverse effects can be increased when Nicardipine is combined with Morphine.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Morphine is combined with Bupropion.
Ticlopidine Ticlopidine The therapeutic efficacy of Ticlopidine can be decreased when used in combination with Morphine.
Saquinavir Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Morphine.
Nisoldipine Nisoldipine The risk or severity of adverse effects can be increased when Morphine is combined with Nisoldipine.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Morphine is combined with Riluzole.
Amifostine Injection Amifostine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Amifostine.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Morphine.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Morphine.
Indinavir Indinavir The metabolism of Morphine can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Morphine can be increased when it is combined with Ritonavir.
Clomipramine Clomipramine The risk or severity of adverse effects can be increased when Morphine is combined with Clomipramine.
Zafirlukast Zafirlukast The metabolism of Morphine can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine Morphine may increase the serotonergic activities of Mirtazapine.
Trandolapril Trandolapril The risk or severity of adverse effects can be increased when Morphine is combined with Trandolapril.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Morphine.
Valsartan Valsartan The risk or severity of adverse effects can be increased when Morphine is combined with Valsartan.
Pramipexole Pramipexole Morphine may increase the sedative activities of Pramipexole.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Morphine is combined with Donepezil.
Nelfinavir Nelfinavir The metabolism of Morphine can be increased when combined with Nelfinavir.
Fexofenadine Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Morphine.
Loratadine Loratadine The metabolism of Morphine can be decreased when combined with Loratadine.
Carvedilol Carvedilol The serum concentration of Morphine can be increased when it is combined with Carvedilol.
Nilutamide Nilutamide The metabolism of Morphine can be decreased when combined with Nilutamide.
Selegiline Selegiline Selegiline may increase the analgesic activities of Morphine.
Sertraline Sertraline The risk or severity of serotonin syndrome can be increased when Morphine is combined with Sertraline.
Propafenone Propafenone The serum concentration of Propafenone can be increased when it is combined with Morphine.
Raloxifene Raloxifene The metabolism of Morphine can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Morphine can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin The risk or severity of adverse effects can be increased when Morphine is combined with Tamsulosin.
Ropinirole Ropinirole Morphine may increase the sedative activities of Ropinirole.
Quetiapine Quetiapine The risk or severity of adverse effects can be increased when Morphine is combined with Quetiapine.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Morphine is combined with Cetirizine.
Paroxetine Paroxetine The risk or severity of serotonin syndrome can be increased when Paroxetine is combined with Morphine.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Morphine is combined with Tolcapone.
Citalopram Citalopram The risk or severity of serotonin syndrome can be increased when Morphine is combined with Citalopram.
Efavirenz Efavirenz The metabolism of Morphine can be decreased when combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Morphine.
Pioglitazone Pioglitazone The metabolism of Morphine can be decreased when combined with Pioglitazone.
Celecoxib Celecoxib The metabolism of Celecoxib can be decreased when combined with Morphine.
Rosiglitazone Rosiglitazone The metabolism of Morphine can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The risk or severity of adverse effects can be increased when Morphine is combined with Tolterodine.
Thalidomide Thalidomide Morphine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Morphine is combined with Levetiracetam.
Rabeprazole Rabeprazole The metabolism of Morphine can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Morphine can be decreased when combined with Terbinafine.

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