J1453 NDC Crosswalk, Billing Units, ASP Payment & Medicare Reimbursement

📋 J1453 summary

J1453 is a HCPCS Level II J-code used to bill fosaprepitant, 1 mg, billed per 1 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J1453: Emend*, Emend, Fosaprepitant Dimeglumine

Code J1453 Billing unit 1 MG Payment limit $0.123/unit NDC-Crosswalk 39 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ1453

DescriptorInjection, fosaprepitant, 1 mg

Billing unit1 MG

Payment limit / unit$0.123

Est. ASP / unit$0.116 est.

Mapped NDCs39

Data periodQ3 2026

Last updated2026-08-20

💊 About Fosaprepitant Dimeglumine DRUG GUIDE

Fosaprepitant dimeglumine injection — available as the brands Emend, Focinvez, and Fosaprepitant Dimeglumine — is used to prevent nausea and vomiting caused by chemotherapy.

It is always given together with other anti-nausea medicines, not on its own.It is approved for both the immediate (acute) and delayed nausea and vomiting linked to highly emetogenic chemotherapy (HEC) — regimens most likely to cause severe nausea, including high-dose cisplatin — and for the delayed nausea and vomiting linked to moderately emetogenic chemotherapy (MEC).

It is not used to treat nausea or vomiting that has already started.

Read the full Fosaprepitant Dimeglumine drug guide →

Clinical overview from our editorial drug guide for Fosaprepitant Dimeglumine. For billing reference, see the sections above.

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).

Medicare payment limit / unit

$0.123

Est. ASP / unit

$0.116 est.

Est. after 2% sequester

$0.121

HCPCS dosage

1 MG

The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.

Full HCPCS code details (official CMS record)

Long descriptionInjection, fosaprepitant, 1 mg

CoverageC — Carrier/MAC judgment

Pricing indicator51 — Drug — priced under the ASP methodology

Type of service1 — Medical care

BETOS-2O1E

ASC payment group—

Action codeN — No maintenance this year

Effective date2022-01-01

Date added2009-01-01

Source: CMS HCPCS Level II code file (imported via admin).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J1453 = 1 mg. Enter a regimen to convert dose → billing units and project a full course.

Dose per administration (mg) Frequency — every days Number of doses NDC / package billed (optional)

Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J1453 WITH EST. MEDICARE PAY

39 NDCs map to J1453. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($0.123/unit) × that package's bill units.

NDC (11-digit)	Drug	Labeler	Package	Strength	Bill units	Est. pay / pkg	NADAC / unit	Status	Source
00006-3061-00	EMEND FOSAPREPITANT DIMEGLUMINE 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Merck	1 VIAL, SINGLE-DOSE in 1 CARTON (0006-3061...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
00143-9384-01	FOSAPREPITANT DIMEGLUMINE 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Hikma	1 VIAL, SINGLE-DOSE in 1 CARTON (0143-9384...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
00143-9428-01	FOSAPREPITANT DIMEGLUMINE 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Hikma	1 VIAL, SINGLE-DOSE in 1 CARTON (0143-9428...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
16714-0248-01	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	NorthStar	1 VIAL, SINGLE-DOSE in 1 CARTON (16714-248...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
43598-0859-11	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Dr.	1 VIAL in 1 CARTON (43598-859-11) / 1 mL...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
43598-0948-11	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Dr.	1 VIAL in 1 CARTON (43598-948-11) / 1 mL...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
55150-0299-01	FOSAPREPITANT DIMEGLUMINE 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Eugia	1 VIAL, SINGLE-DOSE in 1 CARTON (55150-299...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
60505-6105-01	Fosaprepitant	Apotex	—	—	150	$18.45	—	—	CMS + PDAC
63323-0972-10	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Fresenius	1 VIAL, SINGLE-DOSE in 1 CARTON (63323-972...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
67457-0889-10	fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Mylan	1 VIAL, SINGLE-DOSE in 1 CARTON (67457-889...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
68001-0523-36	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	BluePoint	1 VIAL, SINGLE-DOSE in 1 CARTON (68001-523...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
68001-0675-25	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	BluePoint	1 VIAL, SINGLE-DOSE in 1 CARTON (68001-675...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
68180-0690-01	Fosaprepitant	Lupin	—	—	150	$18.45	—	—	CMS + PDAC
70860-0780-10	Fosaprepitant	Athenex	—	—	150	$18.45	—	—	CMS + PDAC
70860-0782-10	Fosaprepitant	Athenex	—	—	150	$18.45	—	—	CMS + PDAC
70860-0783-10	Fosaprepitant	Athenex	—	—	150	$18.45	—	—	CMS ASP
71839-0104-01	fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	BE	1 VIAL, SINGLE-DOSE in 1 CARTON (71839-104...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
72205-0026-01	Fosaprepitant	Novadoz	—	—	150	$18.45	—	—	CMS + PDAC
72205-0054-01	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Novadoz	1 VIAL, SINGLE-DOSE in 1 CARTON (72205-054...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
72205-0083-01	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Novadoz	1 VIAL, SINGLE-DOSE in 1 CARTON (72205-083...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
72603-0450-01	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Northstar	1 VIAL, SINGLE-DOSE in 1 CARTON (72603-450...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
81952-0911-01	Fosaprepitant	Hepalink	—	—	150	$18.45	—	—	CMS + PDAC
83634-0776-10	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Avenacy,	1 VIAL in 1 CARTON (83634-776-10) / 5 mL...	150 mg/5mL	150	$18.45	—	● Active	CMS + PDAC
43598-0671-11	Fosaprepitant 150 mg/1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Dr.	1 VIAL, SINGLE-DOSE in 1 CARTON (43598-671...	150 mg/1	150	$18.45	—	● Active	PDAC
31722-0165-31	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Camber	1 VIAL, SINGLE-DOSE in 1 CARTON (31722-165...	150 mg/5mL	150	$18.45	—	● Active	PDAC
00338-0008-01	Fosaprepitant 150 mg/5mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Baxter	1 VIAL, SINGLE-DOSE in 1 CARTON (0338-0008...	150 mg/5mL	150	$18.45	—	● Active	PDAC
68001-0517-36	FOSAPREPITANT DIMEGLUMINE (SDV,LATEX-FREE) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
16729-0240-03	FOSAPREPITANT DIMEGLUMINE (1X150GM;SDV,PF) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
72603-0106-01	FOSAPREPITANT DIMEGLUMINE (SDV,PF,LATEX-FREE) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
00781-3497-75	FOSAPREPITANT DIMEGLUMINE (SDV,LYOPHILIZED) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
16714-0929-01	FOSAPREPITANT DIMEGLUMINE (SDV,LATEX-FREE) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
72606-0569-01	FOSAPREPITANT DIMEGLUMINE (SDV,LYOPHILIZED) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
16714-0120-01	FOSAPREPITANT DIMEGLUMINE (SDV,LYOPHILIZED) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
69097-0830-37	FOSAPREPITANT DIMEGLUMINE (SDV,LYOPHILIZED) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
68001-0421-22	FOSAPREPITANT DIMEGLUMINE (SDV,LATEX-FREE) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
71288-0418-10	FOSAPREPITANT DIMEGLUMINE (LATEX-FREE,LYOPHILIZED) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
00591-4385-79	Fosaprepitant 150 mg/1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION	Actavis	1 INJECTION, POWDER, LYOPHILIZED, FOR SOLU...	150 mg/1	150	$18.45	—	● Active	PDAC
00006-3061-02	PREMIERPRO RX EMEND (LYOPHILIZED) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC
00006-3061-04	EMEND NOVAPLUS (LYOPHILIZED) 150 MG	Unknown	—	—	150	$18.45	—	—	PDAC

NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

⚠️ Don't confuse J1453 with… RELATED CODES

Adjacent HCPCS codes that share an ingredient or formulation with J1453. Billing units and payment limits differ — confirm the exact code, strength and form before billing.

Code	Descriptor	Billing unit	Payment limit / unit	How it differs from J1453
J1434	FOSAPREPITANT DIMEGLUMINE	1 MG	$2.456	Related ingredient or formulation — confirm strength, form and billing unit before substituting.
J1456	Inj, fosaprepitant (teva)	1 MG	$0.036	Related ingredient or formulation — confirm strength, form and billing unit before substituting.

Related codes matched on shared ingredient (CMS Medicare Part B Spending feed). Billing units and payment limits from the CMS ASP Pricing File. Always verify the precise HCPCS code for the product and strength administered.

📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)

Period

Total Part B spend

$297.3K

Claims

19,071

Beneficiaries

7,087

Spend / beneficiary

$41.95

Spend / claim

$15.59

Trend by period

Where J1453 ranks among Part B drugs · 2026 (Q1) · neighbors ±5

Total spending — #493 of 824

#488 AMBISOME* J0289 $311.8K #489 GRANIX J1447 $308.7K #490 DEPO-TESTOSTERONE* J1071 $304.4K #491 KETOROLAC TROMETHAMI... J1885 $302.9K #492 SUBLOCADE(Q9991) Q9991 $297.3K #493 EMEND* J1453 $297.3K #494 XWRAP 1 SQ CM** Q4204 $288K #495 PACLITAXEL J9267 $286.3K #496 EDETATE CALCIUM DISO... J0600 $284.6K #497 PYRIDOXINE HCL J3415 $283.3K #498 TDVAX* 90714 $282.9K

Total claims — #114 of 824

#109 HYMOVIS ONE* J7322 19,847 #110 OSENVELT* Q5157 19,782 #111 MIDAZOLAM HCL J2250 19,674 #112 RITUXAN J9312 19,253 #113 AZACITIDINE* J9025 19,241 #114 EMEND* J1453 19,071 #115 ALBUKED-25(P9047)* P9047 18,777 #116 MONOFERRIC J1437 18,337 #117 OCTAGAM J1568 18,321 #118 PACLITAXEL J9267 18,259 #119 ENHERTU J9358 18,044

Full breakdown by period (2)

Period	Total spend	Beneficiaries	Claims	$/beneficiary	$/claim
2026 (Q1)	$297.3K	7,087	19,071	$41.95	$15.59
2025 (Q1-Q4)	$1.51M	18,001	87,297	$83.82	$17.28

Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.

📈 Medicare Part B claims detail CMS PSPS · 2024

Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.

Allowed charges

$1.54M

Medicare paid

$1.18M

Submitted services

13,945,161

Denial rate

5.4%

Allowed / service

$0.12

Submitted charges

$56.2M

Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.

🗺️ Where J1453 is utilized CMS · BY PROVIDER · 2024

Medicare Part B services for this code by the rendering provider's state — 11,841,214 services across 47 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.

Hover or tap a state to see its numbers + top ZIP codes.

Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.

📊 What bills under J1453

J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.

NDC products by ingredient

Fosaprepitant 9

Fosaprepitant dimeglumine 5

FOSAPREPITANT DIMEGLUMINE 4

fosaprepitant 4

Fosaprepitant Dimeglumine 1

FOSAPREPITANT 1

fosaprepitant dimeglumine 1

NDC products by labeler

Dr. Reddy's Laboratories Inc., 4

BluePoint Laboratories 3

Hikma Pharmaceuticals USA Inc. 2

Camber Pharmaceuticals, Inc. 2

Mylan Institutional LLC 2

Novadoz Pharmaceuticals LLC 2

Northstar Rx LLC 2

Merck Sharp & Dohme LLC 1

🔗 Related NDC directory pages

🧪 All Fosaprepitant NDCsIngredient 🧪 All Fosaprepitant Dimeglumine NDCsIngredient 🧪 All Fosaprepitant Dimeglumine NDCsIngredient 🧪 All Fosaprepitant NDCsIngredient 🧪 All Fosaprepitant Dimeglumine NDCsIngredient 🧪 All Fosaprepitant NDCsIngredient 🏭 All Dr. labeler NDCsLabeler 43598 🏭 All BluePoint labeler NDCsLabeler 68001 🏭 All Hikma labeler NDCsLabeler 00143 🏭 All Camber labeler NDCsLabeler 31722 📚 All Substance P/Neurokinin-1 Receptor Antagonist NDCsDrug class

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.

HCPCS code & descriptor

CMS HCPCS Level II code file

Loaded

Payment limit & billing unit

CMS Medicare Part B ASP Pricing File (quarterly)

Q3 2026 · as of 2026-08-20

NDC ↔ HCPCS crosswalk

CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)

39 NDCs mapped

NADAC acquisition cost

CMS National Average Drug Acquisition Cost (weekly)

Not available for mapped NDCs

Utilization & spend

CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners

Latest data year 2026

Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J1453 billing FAQ

What is HCPCS code J1453?

J1453 is a HCPCS Level II J-code used to bill Injection, fosaprepitant, 1 mg under Medicare Part B and most medical (not pharmacy) benefits.

What is the billing unit for J1453?

One unit of J1453 represents 1 MG. Report the number of units equal to the dose administered divided by 1 MG.

How many units of J1453 should I bill?

Divide the dose administered by the code's unit size (1 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.

How much does Medicare pay for J1453?

The Medicare Part B payment limit is $0.123 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $0.121 per unit. Payment limits are revised quarterly.

Which NDCs bill under J1453?

39 NDCs currently map to J1453 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.

Does a crosswalk mean J1453 is covered?

No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.

J1453 – Injection, fosaprepitant, 1 mg · NDC Crosswalk & Billing Units