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24 HR metformin hydrochloride 1000 MG / saxagliptin 2.5 MG Extended Release Oral Tablet — RxCUI 1043563

Name: 24 HR metformin hydrochloride 1000 MG / saxagliptin 2.5 MG Extended Release Oral Tabl… (RxCUI 1043563)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1043563 Semantic clinical drug · SCD ● Current RxNorm concept 6 FDA products 6 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1043563

Official name24 HR metformin hydrochloride 1000 MG / saxagliptin 2.5 MG Extended Release Oral Tablet

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asmetformin hydrochloride 1000 MG / saxagliptin (as saxagliptin hydrochloride) 2.5 MG 24 HR Extended Release Oral Tablet; sAXagliptin 2.5 MG / metFORMIN HCl 1000 MG 24HR Extended Release Oral Tablet

FDA products mapped6

Package NDCs mapped6

Reported Medicaid activity (SDUD)646 prescriptions · 4 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Saxagliptin: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It helps lower blood sugar in adults with type 2 diabetes, along with diet and exercise. It isn't for type 1 diabetes or diabetic ketoacidosis.
Take one tablet by mouth once a day, with or without food. Swallow it whole; don't cut, crush or chew it. If you miss a dose, skip it and take the next one on time. Don't double up...
Some people get cold-like symptoms, urinary tract infections or headaches. You might notice swelling in your legs or feet, especially if you also take a TZD diabetes medicine. If y...
Call right away for severe stomach pain that won't go away, shortness of breath, unusual tiredness or swelling, facial or throat swelling, severe joint pain, or skin blisters. Some...

📖 Read our full Saxagliptin guide →

🕸️ Concept Web — How 24 HR metformin hydrochloride 1000 MG / saxaglip... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept 24 HR metformin hydrochloride 1000 MG / saxagliptin 2.5 MG Extended Release Oral Tablet RxCUI 1043563 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 4

The active substance itself — no strength, form, or brand attached yet.
- Metformin 6809 IN
- Saxagliptin 857974 IN
- Metformin / saxagliptin 1043562 MIN
- Metformin hydrochloride 235743 PIN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Kombiglyze 1372730 BN
Dose forms 13

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Metformin / saxagliptin Extended Release Oral Tablet 1043561 SCDF
- Metformin hydrochloride / saxagliptin Extended Release Oral Tablet 2648588 SCDFP
- Metformin / saxagliptin Oral Product 1161605 SCDG
- Metformin / saxagliptin Pill 1161606 SCDG
- Metformin hydrochloride / saxagliptin Oral Product 2659764 SCDGP
- Metformin hydrochloride / saxagliptin Pill 2663373 SCDGP
- Metformin / saxagliptin Extended Release Oral Tablet [Kombiglyze] 1043566 SBDF
- Metformin hydrochloride / saxagliptin Extended Release Oral Tablet [Kombiglyze] 2656899 SBDFP
- +5 more in this family
Clinical & branded drugs 4

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Metformin hydrochloride 1000 MG 860995 SCDC
- Saxagliptin 2.5 MG 858041 SCDC
- 24 HR metformin hydrochloride 1000 MG / saxagliptin 2.5 MG Extended Release Oral Tablet [Kombiglyze] 1043567 SBD
- Metformin hydrochloride 1000 MG / saxagliptin 2.5 MG [Kombiglyze] 1043565 SBDC

Showing up to 8 concepts per family — 17 of 22 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Metformin hydrochloride 1000 MG SCDC · 860995
Saxagliptin 2.5 MG SCDC · 858041
Metformin / saxagliptin Extended Release Oral Tablet SCDF · 1043561
Metformin hydrochloride / saxagliptin Extended Release Oral Tablet SCDFP · 2648588
Metformin / saxagliptin Oral Product SCDG · 1161605
Metformin / saxagliptin Pill SCDG · 1161606
Metformin hydrochloride / saxagliptin Oral Product SCDGP · 2659764
Metformin hydrochloride / saxagliptin Pill SCDGP · 2663373

Brand-Name Concepts

24 HR metformin hydrochloride 1000 MG / saxagliptin 2.5 MG Extended Release Oral Tablet [Kombiglyze] SBD · 1043567
Metformin hydrochloride 1000 MG / saxagliptin 2.5 MG [Kombiglyze] SBDC · 1043565
Metformin / saxagliptin Extended Release Oral Tablet [Kombiglyze] SBDF · 1043566
Metformin hydrochloride / saxagliptin Extended Release Oral Tablet [Kombiglyze] SBDFP · 2656899
Kombiglyze Oral Product SBDG · 1172861
Kombiglyze Pill SBDG · 1172860
Kombiglyze BN · 1372730

📦 FDA Products & Package NDCs

6 products · 6 package NDCs

6 package NDCs map to RxCUI 1043563 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00378-8175-93	30 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTI...	Saxagliptin and Metformin	Mylan Pharmaceuticals Inc.	2023-08-08
00378-8176-91	60 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTI...	Saxagliptin and Metformin	Mylan Pharmaceuticals Inc.	2023-08-08
00378-8177-93	30 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTI...	Saxagliptin and Metformin	Mylan Pharmaceuticals Inc.	2023-08-08
43598-0618-60	60 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (43598-...	Saxagliptin and Metformin Hydrochloride	Dr.Reddys Laboratories Inc	2023-08-09
43598-0619-30	30 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (43598-...	Saxagliptin and Metformin Hydrochloride	Dr.Reddys Laboratories Inc	2023-08-09
43598-0620-30	30 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (43598-...	Saxagliptin and Metformin Hydrochloride	Dr.Reddys Laboratories Inc	2023-08-09

Observed labelers: Dr.Reddys Laboratories Inc (3) · Mylan Pharmaceuticals Inc. (3) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.