Home › NDC Lookup › RxCUI directory › RxCUI 1243679

Acetaminophen 325 MG / guaifenesin 200 MG / phenylephrine hydrochloride 5 MG Oral Tablet — RxCUI 1243679

RxNorm drug concept · Semantic clinical drug
RxCUI 1243679 Semantic clinical drug · SCD ● Current RxNorm concept 111 FDA products 130 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1243679
Official nameAcetaminophen 325 MG / guaifenesin 200 MG / phenylephrine hydrochloride 5 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / GG 200 MG / phenylephrine hydrochloride 5 MG Oral Tablet; acetaminophen 325 MG / guaiFENesin 200 MG / phenylephrine HCl 5 MG Oral Tablet; APAP 325 MG / Guaifenesin 200 MG / Phenylephrine Hydrochloride 5 MG Oral Tablet
FDA products mapped111
Package NDCs mapped130
Reported Medicaid activity (SDUD)76 prescriptions · 1 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 325 MG / guaifenesin 200 MG / phen... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / guaifenesin 200 MG / phenylephrine hydrochloride 5 MG Oral Tablet RxCUI 1243679

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 5

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Guaifenesin 5032
    • Phenylephrine 8163
    • Acetaminophen / guaifenesin / phenylephrine 631158
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / guaifenesin / phenylephrine Oral Tablet 379208
    • Acetaminophen / guaifenesin / phenylephrine hydrochloride Oral Tablet 2646052
    • Acetaminophen / guaifenesin / phenylephrine Oral Product 1151223
    • Acetaminophen / guaifenesin / phenylephrine Pill 1151224
    • Acetaminophen / guaifenesin / phenylephrine hydrochloride Oral Product 2663602
    • Acetaminophen / guaifenesin / phenylephrine hydrochloride Pill 2663122
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Guaifenesin 200 MG 317384
    • Phenylephrine hydrochloride 5 MG 1020198
  4. Packs 2

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 18 of 19 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

111 products · 130 package NDCs
130 package NDCs map to RxCUI 1243679 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
50844-0572-08 2 BLISTER PACK in 1 CARTON (50844-572-08) / 12 TABLET, FILM... Sinus Severe L.N.K. International, Inc. 2021-03-15
51316-0516-09 2 BLISTER PACK in 1 CARTON (51316-516-09) / 10 TABLET, FILM... Mucus Relief Sinus Severe Congestion and Pain CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED 2024-04-03
51316-0927-08 2 BLISTER PACK in 1 CARTON (51316-927-08) / 12 TABLET, FILM... Severe Sinus Pain and Congestion CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED 2025-10-03
53209-1004-02 25 BLISTER PACK in 1 POUCH (53209-1004-2) / 2 TABLET, COATE... Tylenol Sinus Severe Morning Star OTC 2025-06-19
53943-0167-02 2 BLISTER PACK in 1 CARTON (53943-167-02) / 10 TABLET, COAT... Mucus Relief Sinus Severe Congestion Relief DISCOUNT DRUG MART 2013-11-11
53943-0175-02 2 BLISTER PACK in 1 CARTON (53943-175-02) / 12 TABLET, COAT... COLD PLUS HEAD CONGESTION SEVERE DISCOUNT DRUG MART 2014-05-16
53943-0319-05 2 BLISTER PACK in 1 CARTON (53943-319-05) / 12 TABLET, COAT... Sinus Severe DISCOUNT DRUG MART 2009-11-13
55319-0815-19 1 BLISTER PACK in 1 CARTON (55319-815-19) / 8 TABLET, FILM... Severe Congestion and Pain Family Dollar Services Inc 2023-12-13
55910-0529-08 2 BLISTER PACK in 1 CARTON (55910-529-08) / 12 TABLET, FILM... Sinus Severe Daytime DOLGENCORP, LLC 2005-08-06
55910-0927-08 2 BLISTER PACK in 1 CARTON (55910-927-08) / 12 TABLET, FILM... Cold and Head Congestion Severe DOLGENCORP, LLC 2005-08-06
59779-0275-08 2 BLISTER PACK in 1 CARTON (59779-275-08) / 12 TABLET, FILM... Severe Sinus Pain and Congestion Daytime CVS Pharmacy 2005-08-06
63824-0201-44 4 POUCH in 1 CARTON (63824-201-44) / 2 TABLET, COATED in 1... Mucinex Sinus-Max Severe Congestion Relief Reckitt Benckiser LLC 2012-07-23
63824-0241-10 1 BLISTER PACK in 1 CARTON (63824-241-10) / 10 TABLET, FILM... Maximum Strength Mucinex Sinus-Max Severe Congestion and Pain Reckitt Benckiser LLC 2021-07-12
63824-0241-20 2 BLISTER PACK in 1 CARTON (63824-241-20) / 10 TABLET, FILM... Maximum Strength Mucinex Sinus-Max Severe Congestion and Pain Reckitt Benckiser LLC 2018-03-30
63824-0241-44 4 POUCH in 1 CARTON (63824-241-44) / 2 TABLET, FILM COATED... Maximum Strength Mucinex Sinus-Max Severe Congestion and Pain Reckitt Benckiser LLC 2018-03-30
63824-0241-72 2 TABLET, FILM COATED in 1 POUCH (63824-241-72) Maximum Strength Mucinex Sinus-Max Severe Congestion and Pain Reckitt Benckiser LLC 2018-03-30
63824-0243-20 2 BLISTER PACK in 1 CARTON (63824-243-20) / 10 TABLET, COAT... Mucinex Sinus-Max Severe Congestion and Pain, Maximum Strength Reckitt Benckiser LLC 2018-03-31
63868-0071-24 2 BLISTER PACK in 1 CARTON (63868-071-24) / 12 TABLET, COAT... Severe Sinus Congestion and Pain Chain Drug Marketing Association 2009-11-13
63868-0081-24 2 BLISTER PACK in 1 CARTON (63868-081-24) / 12 TABLET, COAT... Severe Cold Head Congestion Chain Drug Marketing Association 2015-09-30
63868-0103-24 2 BLISTER PACK in 1 CARTON (63868-103-24) / 12 TABLET, COAT... Head Congestion Mucus PE CHAIN DRUG MARKETING ASSOCIATION INC 2022-08-03
63868-0722-20 2 BLISTER PACK in 1 CARTON (63868-722-20) / 10 TABLET, COAT... Mucus Relief Sinus Severe Congestion Relief Chain Drug Marketing Association 2015-06-10
63868-0747-24 2 BLISTER PACK in 1 CARTON (63868-747-24) / 12 TABLET, COAT... Pressure Pain Mucus PE Chain Drug Marketing Association 2014-05-21
63941-0167-02 2 BLISTER PACK in 1 CARTON (63941-167-02) / 10 TABLET, COAT... Mucus Relief Sinus Severe Congestion Relief VALU MERCHANDISERS COMPANY 2014-11-13
63941-0173-02 2 BLISTER PACK in 1 CARTON (63941-173-02) / 12 TABLET, COAT... Pressure and Pain Plus Mucus PE VALU MERCHANDISERS COMPANY 2014-11-13
63941-0275-08 2 BLISTER PACK in 1 CARTON (63941-275-08) / 12 TABLET, FILM... Sinus Severe Valu Merchandisers Company 2023-08-08
66715-5544-09 12 BLISTER PACK in 1 CARTON (66715-5544-9) / 2 TABLET, FILM... Non-Drowsy Sinus Severe, Circle K Lil' Drug Store products, Inc. 2022-08-01
66715-5632-03 3 BLISTER PACK in 1 CARTON (66715-5632-3) / 2 TABLET, FILM... Non-Drowsy Sinus Severe, Circle K Lil' Drug Store products, Inc. 2022-08-01
66715-6332-03 1 BLISTER PACK in 1 CARTON (66715-6332-3) / 6 TABLET, FILM... Sinus Relief, Caseys 4good Lil' Drug Store Products, Inc. 2023-08-01
66715-6457-07 25 POUCH in 1 CARTON (66715-6457-7) / 2 TABLET, COATED in 1... Tylenol Sinus Severe, Lil Drug Store Lil Drug Store Products, Inc 2022-04-19
66715-6457-08 30 POUCH in 1 CARTON (66715-6457-8) / 2 TABLET, COATED in 1... Tylenol Sinus Severe, Lil Drug Store Lil Drug Store Products, Inc 2022-04-19
66715-6557-02 2 POUCH in 1 CARTON (66715-6557-2) / 2 TABLET, COATED in 1... Tylenol Sinus Severe, CVP HEALTH Lil Drug Store Products, Inc 2022-05-06
66715-6744-09 12 BLISTER PACK in 1 CARTON (66715-6744-9) / 2 TABLET, FILM... Daytime Sinus Severe Lil' Drug Store Products, Inc. 2022-08-02
66715-7857-02 2 POUCH in 1 CARTON (66715-7857-2) / 2 TABLET, COATED in 1... Tylenol Sinus Severe, TRAVEL BASIX Lil Drug Store Products, Inc 2022-11-30
66715-9757-02 2 POUCH in 1 CARTON (66715-9757-2) / 2 TABLET, COATED in 1... Lil Drug Store Tylenol Sinus Severe Lil Drug Store Products, Inc 2017-10-23
66715-9757-03 3 POUCH in 1 CARTON (66715-9757-3) / 2 TABLET, COATED in 1... Lil Drug Store Tylenol Sinus Severe Lil Drug Store Products, Inc 2019-08-15
67091-0212-24 2 BLISTER PACK in 1 CARTON (67091-212-24) / 12 TABLET, FILM... Cold and Head Congestion Relief Severe WinCo Foods, LLC 2005-08-06
67091-0349-24 2 BLISTER PACK in 1 CARTON (67091-349-24) / 12 TABLET, COAT... Nasal Decongestant PE and Pain Relief Plus Mucus Relief Winco Foods, LLC 2017-10-25
67414-0507-00 2500 POUCH in 1 BOX (67414-507-00) / 2 TABLET, COATED in 1... Tylenol Sinus Severe Jones Healthcare Group - Packaging Services, Inc 2018-01-25
67414-0507-04 50 POUCH in 1 CARTON (67414-507-04) / 2 TABLET, COATED in 1... Tylenol Sinus Severe Jones Healthcare Group - Packaging Services, Inc 2018-01-25
67751-0239-01 1 POUCH in 1 CARTON (67751-239-01) / 2 TABLET, COATED in 1... Tylenol Sinus Severe Navajo Manufacturing Company Inc. 2025-02-19
67751-0239-02 2 POUCH in 1 CARTON (67751-239-02) / 2 TABLET, COATED in 1... Tylenol Sinus Severe Navajo Manufacturing Company Inc. 2025-02-19
68016-0504-24 2 BLISTER PACK in 1 CARTON (68016-504-24) / 12 TABLET, COAT... Sinus Severe CHAIN DRUG CONSORTIUM 2009-11-01
68016-0549-20 2 BLISTER PACK in 1 CARTON (68016-549-20) / 10 TABLET, COAT... Mucus Relief Sinus Severe Congestion Relief CHAIN DRUG CONSORTIUM 2014-09-01
68016-0717-24 2 BLISTER PACK in 1 CARTON (68016-717-24) / 12 TABLET, COAT... Cold and Head Congestion Severe CHAIN DRUG CONSORTIUM 2015-06-01
68998-0175-02 2 BLISTER PACK in 1 CARTON (68998-175-02) / 12 TABLET, COAT... Severe Cold Head Congestion Marc Glassman, Inc. 2015-04-01
68998-0219-05 2 BLISTER PACK in 1 CARTON (68998-219-05) / 12 TABLET, COAT... Sinus Severe MARC GLASSMAN, INC. 2022-10-05
68998-0275-02 2 BLISTER PACK in 1 CARTON (68998-275-02) / 12 TABLET, COAT... Cold plus Head Congestion Severe MARC GLASSMAN, INC. 2022-10-05
69842-0651-01 3 BLISTER PACK in 1 CARTON (69842-651-01) / 10 TABLET, FILM... Congestion and Headache CVS PHARMACY 2020-10-14
69842-0786-02 2 BLISTER PACK in 1 CARTON (69842-786-02) / 10 TABLET, COAT... Mucus Relief Sinus Severe Congestion and Pain CVS PHARMACY 2020-09-01
69842-0882-09 1 KIT in 1 CARTON (69842-882-09) * 10 TABLET, FILM COATED... Sinus Relief Daytime, Nighttime, Maximum Strength CVS PHARMACY 2017-07-01
Observed labelers: Kenvue Brands LLC (6) · Lil Drug Store Products, Inc (6) · Reckitt Benckiser LLC (6) · Select Consumer Group LLC (6) · Walgreen Company (5) · Chain Drug Marketing Association (4) · +40 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.