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Ivacaftor 125 MG / lumacaftor 200 MG Oral Tablet — RxCUI 1655928

RxNorm drug concept · Semantic clinical drug
RxCUI 1655928 Semantic clinical drug · SCD ● Current RxNorm concept 5 FDA products 5 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1655928
Official nameIvacaftor 125 MG / lumacaftor 200 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
FDA products mapped5
Package NDCs mapped5
Reported Medicaid activity (SDUD)291 prescriptions · 7 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Ivacaftor: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
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  • It really does matter what you take it with. Fat in food increases how much ivacaftor your body absorbs — by as much as 2.5 to 4 times. Taking it with just water means you're likel...
  • Why does it have to be taken with food? Can I just take it with water?
📖 Read our full Ivacaftor guide →

🕸️ Concept Web — How Ivacaftor 125 MG / lumacaftor 200 MG Oral Tablet Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Ivacaftor 125 MG / lumacaftor 200 MG Oral Tablet RxCUI 1655928

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 3

    The active substance itself — no strength, form, or brand attached yet.

    • Ivacaftor 1243041
    • Lumacaftor 1655922
    • Ivacaftor / lumacaftor 1655927
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • ORKAMBI 1655929
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Ivacaftor / lumacaftor Oral Tablet 1655926
    • Ivacaftor / lumacaftor Oral Product 1655924
    • Ivacaftor / lumacaftor Pill 1655925
    • Ivacaftor / lumacaftor Oral Tablet [ORKAMBI] 1655931
    • ORKAMBI Oral Product 1655932
    • ORKAMBI Pill 1655933
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 16 of 17 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Ivacaftor 125 MG SCDC · 1655921
  • Lumacaftor 200 MG SCDC · 1655923
  • Ivacaftor / lumacaftor Oral Tablet SCDF · 1655926
  • Ivacaftor / lumacaftor Oral Product SCDG · 1655924
  • Ivacaftor / lumacaftor Pill SCDG · 1655925

Brand-Name Concepts

📦 FDA Products & Package NDCs

5 products · 5 package NDCs
5 package NDCs map to RxCUI 1655928 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
51167-0122-01 56 PACKET in 1 CARTON (51167-122-01) / 1 GRANULE in 1 PACKE... ORKAMBI Vertex Pharmaceuticals Incorporated 2022-09-02
51167-0500-02 56 PACKET in 1 CARTON (51167-500-02) / 1 GRANULE in 1 PACKE... ORKAMBI Vertex Pharmaceuticals Incorporated 2018-08-07
51167-0700-02 4 CARTON in 1 BOX (51167-700-02) / 7 BLISTER PACK in 1 CART... ORKAMBI Vertex Pharmaceuticals Incorporated 2016-09-28
51167-0809-01 4 CARTON in 1 BOX (51167-809-01) / 7 BLISTER PACK in 1 CART... ORKAMBI Vertex Pharmaceuticals Incorporated 2015-07-02
51167-0900-01 56 PACKET in 1 CARTON (51167-900-01) / 1 GRANULE in 1 PACKE... ORKAMBI Vertex Pharmaceuticals Incorporated 2018-08-07
Observed labelers: Vertex Pharmaceuticals Incorporated (5) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.