Piperacillin 4000 MG / tazobactam 500 MG Injection — RxCUI 1659149
RxNorm drug concept · Semantic clinical drug
RxCUI 1659149
Semantic clinical drug · SCD
● Current RxNorm concept 60 FDA products
60 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI1659149
Official namePiperacillin 4000 MG / tazobactam 500 MG Injection
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known aspiperacillin / tazobactam 4.5 GM Injection; piperacillin (as piperacillin sodium) 4000 MG / tazobactam (as tazobactam sodium) 500 MG Injection
FDA products mapped60
Package NDCs mapped60
Reported Medicaid activity (SDUD)52,430 prescriptions · 51 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Piperacillin and Tazobactam Injection: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- Piperacillin and tazobactam is a powerful combination antibiotic used for serious bacterial infections that need IV treatment — things like a ruptured appendix with infection, a ba...
- What is this antibiotic actually treating — why did my doctor choose this one?
- It's given through an IV line directly into your vein, infused slowly over 30 minutes. Most patients receive it every 6 to 8 hours, and a typical course lasts 7 to 14 days dependin...
- How is this medication given, and how long will I need it?
🕸️ Concept Web — How Piperacillin 4000 MG / tazobactam 500 MG Injecti... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Piperacillin 4000 MG / tazobactam 500 MG Injection
RxCUI 1659149 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 3
The active substance itself — no strength, form, or brand attached yet.
-
Piperacillin
8339IN -
Tazobactam
37617IN -
Piperacillin / tazobactam
74169MIN
-
Piperacillin
-
Brand names 1
The same medicine's trade names. A brand name alone says nothing about strength or form.
-
Zosyn
74170BN
-
Zosyn
-
Dose forms 6
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
-
Piperacillin / tazobactam Injection
1659130SCDF -
Piperacillin / tazobactam Injectable Product
1159278SCDG -
Piperacillin / tazobactam Injection [Zosyn]
1659133SBDF -
Zosyn Injectable Product
1186325SBDG -
Injection
1649574DF -
Injectable Product
1151126DFG
-
Piperacillin / tazobactam Injection
-
Clinical & branded drugs 4
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
-
Piperacillin 4000 MG
1659148SCDC -
Tazobactam 500 MG
1656793SCDC -
Piperacillin 4000 MG / tazobactam 500 MG Injection [Zosyn]
1659151SBD -
Piperacillin 4000 MG / tazobactam 500 MG [Zosyn]
1659150SBDC
-
Piperacillin 4000 MG
Showing up to 8 concepts per family — 14 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Piperacillin 4000 MG
SCDC · 1659148 -
Tazobactam 500 MG
SCDC · 1656793 -
Piperacillin / tazobactam Injection
SCDF · 1659130 -
Piperacillin / tazobactam Injectable Product
SCDG · 1159278
Brand-Name Concepts
-
Piperacillin 4000 MG / tazobactam 500 MG Injection [Zosyn]
SBD · 1659151 -
Piperacillin 4000 MG / tazobactam 500 MG [Zosyn]
SBDC · 1659150 -
Piperacillin / tazobactam Injection [Zosyn]
SBDF · 1659133 -
Zosyn Injectable Product
SBDG · 1186325 -
Zosyn
BN · 74170
📦 FDA Products & Package NDCs
60 products · 60 package NDCs
60 package NDCs map to RxCUI 1659149 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00206-8860-02 | 24 BAG in 1 BOX (0206-8860-02) / 50 mL in 1 BAG (0206-8860-... | Zosyn in Galaxy Containers | Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. | 1998-03-01 |
| 00206-8861-02 | 24 BAG in 1 BOX (0206-8861-02) / 50 mL in 1 BAG (0206-8861-... | Zosyn in Galaxy Containers | Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. | 1998-03-01 |
| 00206-8862-02 | 12 BAG in 1 BOX (0206-8862-02) / 100 mL in 1 BAG (0206-8862... | Zosyn in Galaxy Containers | Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. | 1998-03-01 |
| 00264-3446-11 | 24 CONTAINER in 1 CASE (0264-3446-11) / 50 mL in 1 CONTAINE... | Piperacillin and Tazobactam and Sodium Chloride | B. Braun Medical Inc. | 2025-09-30 |
| 00264-3448-11 | 24 CONTAINER in 1 CASE (0264-3448-11) / 50 mL in 1 CONTAINE... | Piperacillin and Tazobactam and Sodium Chloride | B. Braun Medical Inc. | 2025-09-30 |
| 00264-3450-22 | 24 CONTAINER in 1 CASE (0264-3450-22) / 100 mL in 1 CONTAIN... | Piperacillin and Tazobactam and Sodium Chloride | B. Braun Medical Inc. | 2025-09-30 |
| 00338-9632-24 | 24 BAG in 1 CARTON (0338-9632-24) / 50 mL in 1 BAG (0338-96... | Zosyn | Baxter Healthcare Corporation | 2023-04-01 |
| 00338-9636-24 | 24 BAG in 1 CARTON (0338-9636-24) / 50 mL in 1 BAG (0338-96... | Zosyn | Baxter Healthcare Corporation | 2023-04-01 |
| 00338-9638-12 | 12 BAG in 1 CARTON (0338-9638-12) / 100 mL in 1 BAG (0338-9... | Zosyn | Baxter Healthcare Corporation | 2023-04-01 |
| 00781-9210-95 | 10 VIAL, SINGLE-USE in 1 CARTON (0781-9210-95) / 10 mL in 1... | Piperacillin and Tazobactam | Sandoz Inc | 2018-10-05 |
| 00781-9213-95 | 10 VIAL, SINGLE-USE in 1 CARTON (0781-9213-95) / 15 mL in 1... | Piperacillin and Tazobactam | Sandoz Inc | 2018-09-11 |
| 00781-9214-95 | 10 VIAL, SINGLE-USE in 1 CARTON (0781-9214-95) / 20 mL in 1... | Piperacillin and Tazobactam | Sandoz Inc | 2018-10-05 |
| 35369-0501-02 | 10 VIAL, SINGLE-DOSE in 1 CARTON (35369-0501-2) / 20 mL in... | Piperacillin and Tazobactam | Shandong Anxin Pharmaceutical Co., Ltd. | 2018-08-10 |
| 35369-0502-02 | 10 VIAL, SINGLE-DOSE in 1 CARTON (35369-0502-2) / 10 mL in... | Piperacillin and Tazobactam | Shandong Anxin Pharmaceutical Co., Ltd. | 2018-08-10 |
| 35369-0503-02 | 10 VIAL, SINGLE-DOSE in 1 CARTON (35369-0503-2) / 15 mL in... | Piperacillin and Tazobactam | Shandong Anxin Pharmaceutical Co., Ltd. | 2018-08-10 |
| 44567-0801-10 | 10 VIAL in 1 BOX (44567-801-10) / 1 INJECTION, POWDER, FOR... | Piperacillin and Tazobactam | WG Critical Care, LLC | 2009-10-13 |
| 44567-0802-10 | 10 VIAL in 1 BOX (44567-802-10) / 1 INJECTION, POWDER, FOR... | Piperacillin and Tazobactam | WG Critical Care, LLC | 2009-10-13 |
| 44567-0803-10 | 10 VIAL in 1 BOX (44567-803-10) / 1 INJECTION, POWDER, FOR... | Piperacillin and Tazobactam | WG Critical Care, LLC | 2009-10-13 |
| 55150-0119-09 | 10 VIAL in 1 BOX (55150-119-09) / 1 INJECTION, POWDER, LYOP... | Piperacillin and Tazobactam | Eugia US LLC | 2012-01-23 |
| 55150-0119-30 | 10 VIAL in 1 BOX (55150-119-30) / 1 INJECTION, POWDER, LYOP... | Piperacillin and Tazobactam | Eugia US LLC | 2012-01-23 |
| 55150-0120-09 | 10 VIAL in 1 BOX (55150-120-09) / 1 INJECTION, POWDER, LYOP... | Piperacillin and Tazobactam | Eugia US LLC | 2012-01-23 |
| 55150-0120-30 | 10 VIAL in 1 BOX (55150-120-30) / 1 INJECTION, POWDER, LYOP... | Piperacillin and Tazobactam | Eugia US LLC | 2012-01-23 |
| 55150-0121-09 | 10 VIAL in 1 BOX (55150-121-09) / 1 INJECTION, POWDER, LYOP... | Piperacillin and Tazobactam | Eugia US LLC | 2012-01-23 |
| 55150-0121-50 | 10 VIAL in 1 BOX (55150-121-50) / 1 INJECTION, POWDER, LYOP... | Piperacillin and Tazobactam | Eugia US LLC | 2012-01-23 |
| 60505-6156-04 | 10 VIAL, SINGLE-DOSE in 1 CARTON (60505-6156-4) / 10 mL in... | Piperacillin and Tazobactam | Apotex Corp. | 2019-03-15 |
| 60505-6157-04 | 10 VIAL, SINGLE-DOSE in 1 CARTON (60505-6157-4) / 15 mL in... | Piperacillin and Tazobactam | Apotex Corp. | 2019-03-15 |
| 60505-6159-04 | 10 VIAL, SINGLE-DOSE in 1 CARTON (60505-6159-4) / 20 mL in... | Piperacillin and Tazobactam | Apotex Corp. | 2019-03-15 |
| 63323-0300-30 | 10 VIAL in 1 BOX (63323-300-30) / 15 mL in 1 VIAL | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2009-10-13 |
| 63323-0300-36 | 10 VIAL in 1 BOX (63323-300-36) / 15 mL in 1 VIAL | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2009-10-13 |
| 63323-0309-20 | 10 VIAL in 1 BOX (63323-309-20) / 10 mL in 1 VIAL | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2009-10-13 |
| 63323-0309-26 | 10 VIAL in 1 BOX (63323-309-26) / 10 mL in 1 VIAL | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2009-10-13 |
| 63323-0320-50 | 10 VIAL in 1 BOX (63323-320-50) / 20 mL in 1 VIAL | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2009-10-13 |
| 63323-0320-56 | 10 VIAL in 1 BOX (63323-320-56) / 20 mL in 1 VIAL | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2009-10-13 |
| 63323-0981-21 | 10 VIAL, SINGLE-USE in 1 CARTON (63323-981-21) / 10 mL in 1... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2018-05-18 |
| 63323-0981-53 | 10 VIAL, SINGLE-USE in 1 CARTON (63323-981-53) / 10 mL in 1... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2018-05-18 |
| 63323-0982-52 | 10 VIAL, SINGLE-USE in 1 CARTON (63323-982-52) / 20 mL in 1... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2018-05-18 |
| 63323-0982-54 | 10 VIAL, SINGLE-USE in 1 CARTON (63323-982-54) / 20 mL in 1... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2018-05-18 |
| 63323-0983-21 | 10 VIAL, SINGLE-USE in 1 CARTON (63323-983-21) / 15 mL in 1... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2018-05-18 |
| 63323-0983-53 | 10 VIAL, SINGLE-USE in 1 CARTON (63323-983-53) / 15 mL in 1... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2018-05-18 |
| 65219-0259-45 | 10 VIAL, SINGLE-USE in 1 CARTON (65219-259-45) / 20 mL in 1... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2018-05-18 |
| 65219-0259-55 | 10 VIAL, SINGLE-USE in 1 CARTON (65219-259-55) / 20 mL in 1... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2021-05-24 |
| 65219-0434-20 | 10 VIAL, SINGLE-DOSE in 1 CARTON (65219-434-20) / 10 mL in... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2023-03-20 |
| 65219-0436-20 | 10 VIAL, SINGLE-DOSE in 1 CARTON (65219-436-20) / 15 mL in... | Piperacillin and Tazobactam | Fresenius Kabi USA, LLC | 2023-03-20 |
| 68001-0506-30 | 10 VIAL, SINGLE-DOSE in 1 CARTON (68001-506-30) / 10 mL in... | Piperacillin and Tazobactam | BluePoint Laboratories | 2021-08-11 |
| 68001-0507-82 | 10 VIAL, SINGLE-DOSE in 1 CARTON (68001-507-82) / 15 mL in... | Piperacillin and Tazobactam | BluePoint Laboratories | 2021-08-11 |
| 68001-0508-31 | 10 VIAL, SINGLE-DOSE in 1 CARTON (68001-508-31) / 20 mL in... | Piperacillin and Tazobactam | BluePoint Laboratories | 2021-08-11 |
| 72485-0404-10 | 10 VIAL, SINGLE-DOSE in 1 BOX (72485-404-10) / 20 mL in 1 V... | piperacillin and tazobactam | Armas Pharmaceuticals Inc. | 2022-04-14 |
| 72572-0414-10 | 10 VIAL, SINGLE-USE in 1 CARTON (72572-414-10) / 15 mL in 1... | piperacillin and tazobactam | Civica, Inc. | 2025-09-08 |
| 72572-0418-10 | 10 VIAL, SINGLE-USE in 1 CARTON (72572-418-10) / 20 mL in 1... | piperacillin and tazobactam | Civica, Inc. | 2025-09-08 |
| 72572-0573-10 | 10 VIAL, SINGLE-DOSE in 1 CARTON (72572-573-10) / 15 mL in... | Piperacillin and Tazobactam | Civica, Inc. | 2020-12-01 |
Observed labelers:
Fresenius Kabi USA, LLC (16) ·
Eugia US LLC (6) ·
Civica, Inc. (4) ·
Apotex Corp. (3) ·
Avenacy, LLC (3) ·
B. Braun Medical Inc. (3)
· +9 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🧾 Billing Codes (HCPCS)
Medical billing codes (HCPCS "J-codes") that connect to this concept's packages — used mostly when a clinic or hospital bills for a drug it administers. Each code links to its full billing page.
| Code | Descriptor | Mapped packages | Sources |
|---|---|---|---|
| J2543 | Piperacillin/tazobactam | 38 | CMS |
⚠ A crosswalk is not coverage: an NDC↔HCPCS mapping does not guarantee any payer covers or pays the code. Always verify the current payer policy before billing.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.