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Naproxen 250 MG Oral Tablet — RxCUI 198013

RxNorm drug concept · Semantic clinical drug
RxCUI 198013 Semantic clinical drug · SCD ● Current RxNorm concept 66 FDA products 232 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI198013
Official nameNaproxen 250 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
FDA products mapped66
Package NDCs mapped232
Reported Medicaid activity (SDUD)2,444,449 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Naproxen: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It relieves pain, inflammation and fever. Prescription versions treat arthritis, tendonitis, bursitis, acute gout and painful periods. Over-the-counter versions handle minor aches...
  • Take it by mouth with a full glass of water. Over-the-counter products are taken every 8 to 12 hours while symptoms last, and you should use the smallest dose that works. For presc...
  • Headache, indigestion, heartburn, nausea and swelling are common. Call your doctor if you have black stools, vomit blood, a rash, yellow skin or eyes, or chest pain.
  • Usually not. Combining naproxen with other NSAIDs or aspirin raises bleeding risk with little added benefit. Naproxen can also interfere with low-dose aspirin taken for your heart,...
📖 Read our full Naproxen guide →

🕸️ Concept Web — How Naproxen 250 MG Oral Tablet Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Naproxen 250 MG Oral Tablet RxCUI 198013

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Naproxen 7258
  2. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Naproxen Oral Tablet 373005
    • Naproxen Oral Product 1157517
    • Naproxen Pill 1157518
    • Oral Tablet 317541
    • Oral Product 1151131
    • Pill 1151133
  3. Clinical & branded drugs 1

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Naproxen 250 MG 316326

Showing up to 8 concepts per family — 8 of 8 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Naproxen 250 MG SCDC · 316326
  • Naproxen Oral Tablet SCDF · 373005
  • Naproxen Oral Product SCDG · 1157517
  • Naproxen Pill SCDG · 1157518

📦 FDA Products & Package NDCs

66 products · 232 package NDCs
232 package NDCs map to RxCUI 198013 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
25000-0138-03 30 TABLET in 1 BOTTLE (25000-138-03) Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0138-14 1000 TABLET in 1 BOTTLE (25000-138-14) Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0138-21 4 BAG in 1 BOX (25000-138-21) / 7500 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0138-31 6 BAG in 1 BOX (25000-138-31) / 7500 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0138-98 1 BAG in 1 BOX (25000-138-98) / 37950 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0139-03 30 TABLET in 1 BOTTLE (25000-139-03) Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0139-14 1000 TABLET in 1 BOTTLE (25000-139-14) Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0139-22 4 BAG in 1 BOX (25000-139-22) / 4500 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0139-32 6 BAG in 1 BOX (25000-139-32) / 4500 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0139-98 1 BAG in 1 BOX (25000-139-98) / 25300 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0140-03 30 TABLET in 1 BOTTLE (25000-140-03) Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0140-14 1000 TABLET in 1 BOTTLE (25000-140-14) Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0140-19 4 BAG in 1 BOX (25000-140-19) / 3500 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0140-29 6 BAG in 1 BOX (25000-140-29) / 3500 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
25000-0140-98 1 BAG in 1 BOX (25000-140-98) / 18975 TABLET in 1 BAG Naproxen MARKSANS PHARMA LIMITED 2011-02-28
43063-0600-06 6 TABLET in 1 BOTTLE, PLASTIC (43063-600-06) Naproxen PD-Rx Pharmaceuticals, Inc. 2015-08-26
43063-0600-15 15 TABLET in 1 BOTTLE, PLASTIC (43063-600-15) Naproxen PD-Rx Pharmaceuticals, Inc. 2015-08-26
43063-0600-20 20 TABLET in 1 BOTTLE, PLASTIC (43063-600-20) Naproxen PD-Rx Pharmaceuticals, Inc. 2015-08-26
43063-0600-30 30 TABLET in 1 BOTTLE, PLASTIC (43063-600-30) Naproxen PD-Rx Pharmaceuticals, Inc. 2015-08-26
43063-0600-60 60 TABLET in 1 BOTTLE, PLASTIC (43063-600-60) Naproxen PD-Rx Pharmaceuticals, Inc. 2015-08-26
43353-0211-53 60 TABLET in 1 BOTTLE (43353-211-53) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-18
43353-0211-70 120 TABLET in 1 BOTTLE (43353-211-70) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-18
43353-0211-80 180 TABLET in 1 BOTTLE (43353-211-80) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-18
43353-0216-60 90 TABLET in 1 BOTTLE (43353-216-60) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-18
43353-0216-70 120 TABLET in 1 BOTTLE (43353-216-70) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-18
43353-0216-80 180 TABLET in 1 BOTTLE (43353-216-80) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-22
43353-0216-94 360 TABLET in 1 BOTTLE (43353-216-94) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-22
43353-0218-53 60 TABLET in 1 BOTTLE (43353-218-53) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-18
43353-0218-80 180 TABLET in 1 BOTTLE (43353-218-80) Naproxen Aphena Pharma Solutions - Tennessee, LLC 2016-08-18
49483-0617-01 100 TABLET in 1 BOTTLE, PLASTIC (49483-617-01) NAPROXEN TIME CAP LABORATORIES 2016-07-06
49483-0617-50 500 TABLET in 1 BOTTLE, PLASTIC (49483-617-50) NAPROXEN TIME CAP LABORATORIES 2016-07-06
49483-0618-01 100 TABLET in 1 BOTTLE, PLASTIC (49483-618-01) NAPROXEN TIME CAP LABORATORIES 2016-07-06
49483-0618-50 500 TABLET in 1 BOTTLE, PLASTIC (49483-618-50) NAPROXEN TIME CAP LABORATORIES 2016-07-06
49483-0619-01 100 TABLET in 1 BOTTLE, PLASTIC (49483-619-01) NAPROXEN TIME CAP LABORATORIES 2016-07-06
49483-0619-50 500 TABLET in 1 BOTTLE, PLASTIC (49483-619-50) NAPROXEN TIME CAP LABORATORIES 2016-07-06
50090-2788-04 30 TABLET in 1 BOTTLE (50090-2788-4) Naproxen A-S Medication Solutions 2017-01-18
50090-4752-04 30 TABLET in 1 BOTTLE (50090-4752-4) Naproxen A-S Medication Solutions 2019-11-26
50228-0434-01 100 TABLET in 1 BOTTLE (50228-434-01) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0434-05 500 TABLET in 1 BOTTLE (50228-434-05) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0434-10 1000 TABLET in 1 BOTTLE (50228-434-10) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0434-30 30 TABLET in 1 BOTTLE (50228-434-30) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0435-01 100 TABLET in 1 BOTTLE (50228-435-01) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0435-05 500 TABLET in 1 BOTTLE (50228-435-05) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0435-10 1000 TABLET in 1 BOTTLE (50228-435-10) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0435-30 30 TABLET in 1 BOTTLE (50228-435-30) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0436-01 100 TABLET in 1 BOTTLE (50228-436-01) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0436-05 500 TABLET in 1 BOTTLE (50228-436-05) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0436-10 1000 TABLET in 1 BOTTLE (50228-436-10) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50228-0436-30 30 TABLET in 1 BOTTLE (50228-436-30) Naproxen ScieGen Pharmaceuticals, Inc. 2020-03-01
50268-0594-15 50 BLISTER PACK in 1 BOX, UNIT-DOSE (50268-594-15) / 1 TABL... Naproxen AvPAK 2015-02-11
Observed labelers: Bryant Ranch Prepack (33) · Sportpharm LLC (27) · Asclemed USA, Inc. (20) · MARKSANS PHARMA LIMITED (15) · Aphena Pharma Solutions - Tennessee, LLC (13) · Glenmark Pharmaceuticals Inc., USA (12) · +18 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.