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Acetaminophen 500 MG / chlorpheniramine maleate 4 MG / phenylephrine hydrochloride 10 MG O... — RxCUI 2463332

RxNorm drug concept · Semantic clinical drug
RxCUI 2463332 Semantic clinical drug · SCD ● Current RxNorm concept 6 FDA products 18 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2463332
Official nameAcetaminophen 500 MG / chlorpheniramine maleate 4 MG / phenylephrine hydrochloride 10 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 500 MG / chlorpheniramine maleate 4 MG / phenylephrine hydrochloride 10 MG Oral Tablet; acetaminophen 500 MG / chlorpheniramine maleate 4 MG / phenylephrine HCl 10 MG Oral Tablet
FDA products mapped6
Package NDCs mapped18
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 500 MG / chlorpheniramine maleate... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 500 MG / chlorpheniramine maleate 4 MG / phenylephrine hydrochloride 10 MG Oral Tablet RxCUI 2463332

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 6

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Chlorpheniramine 2400
    • Phenylephrine 8163
    • Acetaminophen / chlorpheniramine / phenylephrine 689583
    • Chlorpheniramine maleate 142429
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / chlorpheniramine / phenylephrine Oral Tablet 374739
    • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Oral Tablet 2646973
    • Acetaminophen / chlorpheniramine / phenylephrine Oral Product 1155249
    • Acetaminophen / chlorpheniramine / phenylephrine Pill 1155250
    • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Oral Product 2663536
    • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Pill 2662311
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 500 MG 315266
    • Chlorpheniramine maleate 4 MG 998253
    • Phenylephrine hydrochloride 10 MG 996705

Showing up to 8 concepts per family — 17 of 18 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 500 MG SCDC · 315266
  • Chlorpheniramine maleate 4 MG SCDC · 998253
  • Phenylephrine hydrochloride 10 MG SCDC · 996705
  • Acetaminophen / chlorpheniramine / phenylephrine Oral Tablet SCDF · 374739
  • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Oral Tablet SCDFP · 2646973
  • Acetaminophen / chlorpheniramine / phenylephrine Oral Product SCDG · 1155249
  • Acetaminophen / chlorpheniramine / phenylephrine Pill SCDG · 1155250
  • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Oral Product SCDGP · 2663536
  • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Pill SCDGP · 2662311

📦 FDA Products & Package NDCs

6 products · 18 package NDCs
18 package NDCs map to RxCUI 2463332 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
69729-0122-06 3 PACKET in 1 CARTON (69729-122-06) / 2 TABLET in 1 PACKET Acetaminophen, Chlorpheniramine Maleate, Phenylephrine HCl OPMX LLC 2023-09-04
69729-0122-37 12 TABLET in 1 POUCH (69729-122-37) Acetaminophen, Chlorpheniramine Maleate, Phenylephrine HCl OPMX LLC 2019-08-26
69729-0122-38 144 TABLET in 1 POUCH (69729-122-38) Acetaminophen, Chlorpheniramine Maleate, Phenylephrine HCl OPMX LLC 2019-08-26
69729-0133-06 3 POUCH in 1 CARTON (69729-133-06) / 2 TABLET in 1 POUCH COLDTAC ULTRA OPMX LLC 2024-01-10
69729-0133-27 2 TABLET in 1 POUCH (69729-133-27) COLDTAC ULTRA OPMX LLC 2024-01-10
69729-0133-37 6 POUCH in 1 CARTON (69729-133-37) / 2 TABLET in 1 POUCH COLDTAC ULTRA OPMX LLC 2024-01-10
69729-0133-38 72 POUCH in 1 CARTON (69729-133-38) / 2 TABLET in 1 POUCH COLDTAC ULTRA OPMX LLC 2024-01-10
69729-0223-02 2 TABLET in 1 POUCH (69729-223-02) Pentrexcilina Daytime OPMX LLC 2020-12-30
69729-0223-06 3 POUCH in 1 CARTON (69729-223-06) / 2 TABLET in 1 POUCH Pentrexcilina Daytime OPMX LLC 2024-01-10
69729-0223-37 6 POUCH in 1 CARTON (69729-223-37) / 2 TABLET in 1 POUCH Pentrexcilina Daytime OPMX LLC 2024-01-10
69729-0223-38 72 POUCH in 1 CARTON (69729-223-38) / 2 TABLET in 1 POUCH Pentrexcilina Daytime OPMX LLC 2020-12-30
69729-0322-27 2 TABLET in 1 POUCH (69729-322-27) Acetaminophen, Chlorpheniramine Maleate, Phenylephrine HCl OPMX LLC 2019-08-26
69729-0322-37 12 TABLET in 1 POUCH (69729-322-37) Acetaminophen, Chlorpheniramine Maleate, Phenylephrine HCl OPMX LLC 2019-08-26
69729-0322-38 144 TABLET in 1 POUCH (69729-322-38) Acetaminophen, Chlorpheniramine Maleate, Phenylephrine HCl OPMX LLC 2019-08-26
69729-0323-27 2 TABLET in 1 POUCH (69729-323-27) RESFRIOL D OPMX LLC 2024-01-10
69729-0323-37 6 POUCH in 1 CARTON (69729-323-37) / 2 TABLET in 1 POUCH RESFRIOL D OPMX LLC 2024-01-10
69729-0323-38 72 POUCH in 1 CARTON (69729-323-38) / 2 TABLET in 1 POUCH RESFRIOL D OPMX LLC 2024-01-10
69729-0829-30 1 BLISTER PACK in 1 CARTON (69729-829-30) / 30 TABLET in 1... DESENFRIOL D OPMX LLC 2026-06-18
Observed labelers: OPMX LLC (18) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.