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Naloxone hydrochloride 16 MG/ML Nasal Spray [Rextovy] — RxCUI 2680741

RxNorm drug concept · Semantic branded drug
RxCUI 2680741 Semantic branded drug · SBD ● Current RxNorm concept 1 FDA product 1 package NDC Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2680741
Official nameNaloxone hydrochloride 16 MG/ML Nasal Spray [Rextovy]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asRextovy 4 MG per 0.25 ML Nasal Spray; REXTOVY 4 MG in 0.25 ML Nasal Spray
FDA products mapped1
Package NDCs mapped1
Reported Medicaid activity (SDUD)926 prescriptions · 16 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Naloxone Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It reverses the effects of opioids in an emergency, especially dangerously slow breathing. Zimhi is for known or suspected opioid overdose. Another naloxone injection is for milita...
  • Yes, always. Naloxone can wear off before the opioid does, so the overdose can come back. Stay with the person until emergency responders arrive.
  • Do I still need to call 911 after giving it?
  • You inject it into the outer thigh, through clothing if needed, then slide the safety guard over the needle with one hand. Never recap the needle. If there is no response in 2 to 3...
📖 Read our full Naloxone Injection guide →

🕸️ Concept Web — How Naloxone hydrochloride 16 MG/ML Nasal Spray [Rex... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Naloxone hydrochloride 16 MG/ML Nasal Spray [Rextovy] RxCUI 2680741

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 2

    The active substance itself — no strength, form, or brand attached yet.

    • Naloxone 7242
    • Naloxone hydrochloride 203192
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Rextovy 2680735
  3. Dose forms 13

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Naloxone Nasal Spray 1725058
    • Naloxone hydrochloride Nasal Spray 2648679
    • Naloxone Inhalant Product 1725056
    • Naloxone Nasal Product 1725057
    • Naloxone hydrochloride Inhalant Product 2660326
    • Naloxone hydrochloride Nasal Product 2663067
    • Naloxone Nasal Spray [Rextovy] 2680739
    • Naloxone hydrochloride Nasal Spray [Rextovy] 2680740
    • +5 more in this family
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 14 of 19 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Naloxone hydrochloride 16 MG/ML Nasal Spray SCD · 2637879
  • Naloxone hydrochloride 16 MG/ML SCDC · 2637878
  • Naloxone Nasal Spray SCDF · 1725058
  • Naloxone hydrochloride Nasal Spray SCDFP · 2648679
  • Naloxone Inhalant Product SCDG · 1725056
  • Naloxone Nasal Product SCDG · 1725057
  • Naloxone hydrochloride Inhalant Product SCDGP · 2660326
  • Naloxone hydrochloride Nasal Product SCDGP · 2663067

Brand-Name Concepts

  • Naloxone hydrochloride 16 MG/ML [Rextovy] SBDC · 2680736
  • Naloxone Nasal Spray [Rextovy] SBDF · 2680739
  • Naloxone hydrochloride Nasal Spray [Rextovy] SBDFP · 2680740
  • Rextovy Inhalant Product SBDG · 2680737
  • Rextovy Nasal Product SBDG · 2680738
  • Rextovy BN · 2680735

📦 FDA Products & Package NDCs

1 product · 1 package NDC
1 package NDC map to RxCUI 2680741 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
76329-3669-02 2 CONTAINER in 1 CONTAINER (76329-3669-2) / .25 mL in 1 CON... REXTOVY International Medication Systems, Ltd. 2024-05-07
Observed labelers: International Medication Systems, Ltd. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.