Adapalene 0.001 MG/MG Topical Gel — RxCUI 307731
RxNorm drug concept · Semantic clinical drug
RxCUI 307731
Semantic clinical drug · SCD
● Current RxNorm concept 40 FDA products
59 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI307731
Official nameAdapalene 0.001 MG/MG Topical Gel
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asadapalene 0.1 % Topical Gel
FDA products mapped40
Package NDCs mapped59
Reported Medicaid activity (SDUD)30,018 prescriptions · 29 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Adapalene: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- It treats acne vulgaris, the common type of acne. Some products are labeled for ages 12 and up. Ask a doctor before using it in younger children.
- Use it once a day, usually in the evening, on clean, dry skin. Apply a thin layer to the whole affected area and keep it away from your eyes, lips and inside of your mouth or nose....
- Give it about 8 to 12 weeks. Acne can seem to flare in the early weeks, which is not a reason to stop. If you see no improvement after 12 weeks, talk to your prescriber.
- Redness, dryness, peeling and some burning or stinging are the most common, especially in the first month. They are usually mild to moderate and often ease. A moisturizer can help....
🕸️ Concept Web — How Adapalene 0.001 MG/MG Topical Gel Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Adapalene 0.001 MG/MG Topical Gel
RxCUI 307731 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 1
The active substance itself — no strength, form, or brand attached yet.
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Adapalene
60223IN
-
Adapalene
-
Brand names 1
The same medicine's trade names. A brand name alone says nothing about strength or form.
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Differin
153184BN
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Differin
-
Dose forms 6
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
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Adapalene Topical Gel
377966SCDF -
Adapalene Topical Product
1163694SCDG -
Adapalene Topical Gel [Differin]
370379SBDF -
Differin Topical Product
1167536SBDG -
Topical Gel
346286DF -
Topical Product
1151122DFG
-
Adapalene Topical Gel
-
Clinical & branded drugs 3
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
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Adapalene 0.001 MG/MG
340054SCDC -
Adapalene 0.001 MG/MG Topical Gel [Differin]
153183SBD -
Adapalene 0.001 MG/MG [Differin]
565195SBDC
-
Adapalene 0.001 MG/MG
Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
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Adapalene 0.001 MG/MG
SCDC · 340054 -
Adapalene Topical Gel
SCDF · 377966 -
Adapalene Topical Product
SCDG · 1163694
Brand-Name Concepts
-
Adapalene 0.001 MG/MG Topical Gel [Differin]
SBD · 153183 -
Adapalene 0.001 MG/MG [Differin]
SBDC · 565195 -
Adapalene Topical Gel [Differin]
SBDF · 370379 -
Differin Topical Product
SBDG · 1167536 -
Differin
BN · 153184
📦 FDA Products & Package NDCs
40 products · 59 package NDCs
59 package NDCs map to RxCUI 307731 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00299-4910-00 | 1 TUBE in 1 BLISTER PACK (0299-4910-00) / 2 g in 1 TUBE | Differin | Galderma Laboratories, L.P. | 2016-07-08 |
| 00299-4910-10 | 1 BOTTLE, PUMP in 1 CARTON (0299-4910-10) / 15 g in 1 BOTTL... | Differin | Galderma Laboratories, L.P. | 2020-01-01 |
| 00299-4910-15 | 1 TUBE in 1 CARTON (0299-4910-15) / 15 g in 1 TUBE | Differin | Galderma Laboratories, L.P. | 2016-07-08 |
| 00299-4910-40 | 1 BOTTLE, PUMP in 1 CARTON (0299-4910-40) / 45 g in 1 BOTTL... | Differin | Galderma Laboratories, L.P. | 2020-01-01 |
| 00299-4910-45 | 1 TUBE in 1 CARTON (0299-4910-45) / 45 g in 1 TUBE | Differin | Galderma Laboratories, L.P. | 2016-07-08 |
| 00316-0143-15 | 1 TUBE in 1 CARTON (0316-0143-15) / 15 g in 1 TUBE | PanOxyl | CROWN LABORATORIES | 2023-02-06 |
| 00316-0284-15 | 1 TUBE in 1 CARTON (0316-0284-15) / 15 g in 1 TUBE | PanOxyl | CROWN LABORATORIES | 2025-08-08 |
| 00363-0888-05 | 1 TUBE in 1 CARTON (0363-0888-05) / 15 g in 1 TUBE | Adapalene | Walgreens | 2021-04-30 |
| 00363-0888-16 | 1 TUBE in 1 CARTON (0363-0888-16) / 45 g in 1 TUBE | Adapalene | Walgreens | 2021-04-30 |
| 00363-1401-05 | 1 TUBE in 1 CARTON (0363-1401-05) / 15 g in 1 TUBE | Adapalene | Walgreens | 2023-10-25 |
| 00363-1401-16 | 1 TUBE in 1 CARTON (0363-1401-16) / 45 g in 1 TUBE | Adapalene | Walgreens | 2023-10-25 |
| 00363-4110-05 | 1 TUBE in 1 CARTON (0363-4110-05) / 15 g in 1 TUBE | Adapalene | Walgreens | 2025-07-01 |
| 00363-4110-16 | 1 TUBE in 1 CARTON (0363-4110-16) / 45 g in 1 TUBE | Adapalene | Walgreens | 2025-07-01 |
| 00536-1412-20 | 1 TUBE in 1 CARTON (0536-1412-20) / 15 g in 1 TUBE | ADAPALENE | RUGBY LABORATORIES, INC. | 2024-02-20 |
| 00536-1412-26 | 1 TUBE in 1 CARTON (0536-1412-26) / 45 g in 1 TUBE | ADAPALENE | RUGBY LABORATORIES, INC. | 2024-02-20 |
| 11410-0224-30 | 1 KIT in 1 BOX (11410-224-30) * 1 TUBE in 1 BOX (11410-958... | Proactiv MD Kit | Alchemee, LLC | 2024-05-08 |
| 11410-0958-15 | 1 TUBE in 1 BOX (11410-958-15) / 15 g in 1 TUBE | Proactiv MD Adapalene Acne Treatment | Alchemee, LLC | 2023-11-16 |
| 11410-0958-45 | 1 TUBE in 1 BOX (11410-958-45) / 45 g in 1 TUBE | Proactiv MD Adapalene Acne Treatment | Alchemee, LLC | 2023-11-16 |
| 11822-0062-01 | 1 TUBE in 1 CARTON (11822-0062-1) / 15 g in 1 TUBE | ADAPALENE | RITE AID | 2024-04-15 |
| 21130-0754-05 | 1 TUBE in 1 CARTON (21130-754-05) / 15 g in 1 TUBE | Adapalene | Safeway, Inc. | 2024-01-31 |
| 30142-0725-05 | 1 TUBE in 1 CARTON (30142-725-05) / 15 g in 1 TUBE | Adapalene | The Kroger Co. | 2024-03-15 |
| 36800-0088-05 | 1 TUBE in 1 CARTON (36800-088-05) / 15 g in 1 TUBE | Adapalene | TOP CARE (Topco Associates LLC) | 2020-07-30 |
| 41250-0288-05 | 1 TUBE in 1 CARTON (41250-288-05) / 15 g in 1 TUBE | Adapalene | MEIJER, INC. | 2019-11-29 |
| 46122-0768-36 | 1 TUBE in 1 CARTON (46122-768-36) / 15 g in 1 TUBE | Adapalene | AMERISOURCE BERGEN | 2024-02-26 |
| 49967-0354-01 | 1 TUBE in 1 CARTON (49967-354-01) / 45 g in 1 TUBE | Adapalene | LOreal USA Products Inc | 2019-11-29 |
| 49967-0354-02 | 1 TUBE in 1 CARTON (49967-354-02) / 15 g in 1 TUBE | Adapalene | LOreal USA Products Inc | 2019-09-18 |
| 49967-0591-01 | 1 TUBE in 1 CARTON (49967-591-01) / 45 g in 1 TUBE | Effaclar | LOreal USA Products Inc | 2019-08-23 |
| 49967-0591-02 | 1 TUBE in 1 CARTON (49967-591-02) / 3 g in 1 TUBE | Effaclar | LOreal USA Products Inc | 2019-10-22 |
| 49967-0592-01 | 1 TUBE in 1 CARTON (49967-592-01) / 45 g in 1 TUBE | Effaclar | LOreal USA Products Inc | 2024-09-16 |
| 49967-0592-02 | 1 TUBE in 1 CARTON (49967-592-02) / 3 g in 1 TUBE | Effaclar | LOreal USA Products Inc | 2024-09-16 |
| 51316-0114-05 | 1 TUBE in 1 CARTON (51316-114-05) / 15 g in 1 TUBE | Adapalene | CVS PHARMACY, INC | 2023-10-31 |
| 51316-0114-16 | 1 TUBE in 1 CARTON (51316-114-16) / 45 g in 1 TUBE | Adapalene | CVS PHARMACY, INC | 2023-10-31 |
| 51672-2150-01 | 1 TUBE in 1 CARTON (51672-2150-1) / 15 g in 1 TUBE | Adapalene | Sun Pharmaceutical Industries, Inc. | 2022-01-14 |
| 51672-2150-06 | 1 TUBE in 1 CARTON (51672-2150-6) / 45 g in 1 TUBE | Adapalene | Sun Pharmaceutical Industries, Inc. | 2022-01-14 |
| 55910-0880-05 | 1 TUBE in 1 CARTON (55910-880-05) / 15 g in 1 TUBE | Adapalene | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | 2019-11-29 |
| 59726-0114-05 | 1 TUBE in 1 CARTON (59726-114-05) / 15 g in 1 TUBE | Adapalene | P & L Development, LLC | 2023-11-30 |
| 59726-0888-05 | 1 TUBE in 1 CARTON (59726-888-05) / 15 g in 1 TUBE | Adapalene | P & L Development, LLC | 2021-05-28 |
| 69842-0088-05 | 1 TUBE in 1 CARTON (69842-088-05) / 15 g in 1 TUBE | Adapalene | CVS Pharmacy | 2019-08-01 |
| 69842-0088-16 | 1 TUBE in 1 CARTON (69842-088-16) / 45 g in 1 TUBE | Adapalene | CVS Pharmacy | 2019-08-01 |
| 69968-0826-01 | 1 TUBE in 1 CARTON (69968-0826-1) / 45 g in 1 TUBE | Neutrogena Adapalene 0.1% Acne Treatment | Kenvue Brands LLC | 2023-12-04 |
| 69968-0945-02 | 1 TUBE in 1 CARTON (69968-0945-2) / 15 g in 1 TUBE | Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatment | Kenvue Brands LLC | 2025-11-25 |
| 69968-1004-02 | 1 TUBE in 1 CARTON (69968-1004-2) / 15 g in 1 TUBE | Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatment | Kenvue Brands LLC | 2025-11-25 |
| 70000-0666-01 | 1 TUBE in 1 CARTON (70000-0666-1) / 15 g in 1 TUBE | ADAPALENE | Cardinal Health | 2024-03-17 |
| 70000-0666-02 | 1 TUBE in 1 CARTON (70000-0666-2) / 45 g in 1 TUBE | ADAPALENE | Cardinal Health | 2024-03-17 |
| 72559-0015-13 | 1 TUBE in 1 CARTON (72559-015-13) / 45 g in 1 TUBE | Curist Acne Relief | Little Pharma, Inc. | 2022-08-15 |
| 72559-0015-17 | 2 CARTON in 1 PACKAGE, COMBINATION (72559-015-17) / 1 TUBE... | Curist Acne Relief | Little Pharma, Inc. | 2024-06-21 |
| 72657-0158-15 | 1 BOTTLE, PUMP in 1 CARTON (72657-158-15) / 15 g in 1 BOTTL... | Adapalene | GLENMARK THERAPEUTICS INC., USA | 2025-03-14 |
| 72657-0158-17 | 1 TUBE in 1 CARTON (72657-158-17) / 15 g in 1 TUBE | Adapalene | GLENMARK THERAPEUTICS INC., USA | 2023-03-10 |
| 72657-0158-45 | 1 BOTTLE, PUMP in 1 CARTON (72657-158-45) / 45 g in 1 BOTTL... | Adapalene | GLENMARK THERAPEUTICS INC., USA | 2025-03-14 |
| 72657-0158-55 | 1 TUBE in 1 CARTON (72657-158-55) / 45 g in 1 TUBE | Adapalene | GLENMARK THERAPEUTICS INC., USA | 2023-03-10 |
Observed labelers:
LOreal USA Products Inc (6) ·
Walgreens (6) ·
Galderma Laboratories, L.P. (5) ·
GLENMARK THERAPEUTICS INC., USA (4) ·
YYBA Corp (4) ·
Alchemee, LLC (3)
· +21 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.